Projects per year
Search results
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Active
KHP Experimental Cancer Medicine Centre
Spicer, J. (Primary Investigator), Gillett, C. (Co-Investigator), Purushotham, A. (Co-Investigator) & Sarker, D. (Co-Investigator)
1/04/2023 → 31/03/2028
Project: Research
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CoL: CRUK City of London Centre renewal (COLMC)
Ng, T. (Primary Investigator), Arnold, J. (Co-Investigator), Blower, P. (Co-Investigator), Ciccarelli, F. (Co-Investigator), Dazzi, F. (Co-Investigator), Farzaneh, F. (Co-Investigator), Grigoriadis, A. (Co-Investigator), Hayday, A. (Co-Investigator), Irshad, S. (Co-Investigator), Kong, A. (Co-Investigator), Kordasti, S. (Co-Investigator), Lawrence, T. (Co-Investigator), Mishto, M. (Co-Investigator), Papa, S. (Co-Investigator), Purushotham, A. (Co-Investigator), Quek, L. (Co-Investigator), Ramsay, A. (Co-Investigator), Reis Ferreira, M. (Co-Investigator), Sarker, D. (Co-Investigator), Sinkus, R. (Co-Investigator), Spicer, J. (Co-Investigator) & Witney, T. (Co-Investigator)
1/04/2022 → 31/03/2027
Project: Research
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Finished
A Cancer Research UK study of MOv18 IgE, a first in class chimeric IgE antibody against folate receptor-α, effects on monocyte phenotype and function
Karagiannis, S. (Primary Investigator), Bax, H. (Co-Investigator) & Spicer, J. (Co-Investigator)
15/01/2024 → 31/01/2025
Project: Research
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Heme oxygenase-1 inhibition for the immunotherapy treatment of cancer
Arnold, J. (Primary Investigator), Rahman, M. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/01/2021 → 31/12/2021
Project: Research
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Antibody-drug conjugates (ADCs) for the treatment of solid tumours
Karagiannis, S. (Primary Investigator) & Spicer, J. (Co-Investigator)
1/10/2020 → 30/01/2025
Project: Research
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Immunotherapy of head and neck cancer using T4 CAR T-cells potentiated by lymphodepletion and nivolumab
Maher, J. (Primary Investigator), Papa, S. (Co-Investigator), Spicer, J. (Co-Investigator) & Reid, F. (Co-Investigator)
J P Moulton Charitable Foundation
2/01/2020 → 31/12/2023
Project: Research
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VAPER: A Phase 1 Cancer Vaccine Trial
Spicer, J. (Primary Investigator) & Farzaneh, F. (Co-Investigator)
11/09/2018 → 4/06/2021
Project: Research
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PET metallomics in cancer: predicting response to platinum drugs
Blower, P. (Primary Investigator), Spicer, J. (Co-Investigator) & Barrington, S. (Co-Investigator)
28/02/2018 → 27/02/2019
Project: Research
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Immunotherapy for mesothelioma using ErbB re-targeted CAR T-cells in combination with PD-1 checkpoint inhibition
Maher, J. (Primary Investigator), Davies, D. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/04/2017 → 31/05/2020
Project: Research
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Preclinical efficacy of an antibody of the IgE class against a melanoma-associated antigen
Karagiannis, S. (Primary Investigator) & Spicer, J. (Primary Investigator)
1/04/2017 → 31/12/2021
Project: Research
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KHP Centre Award - Non-Clinical Training Award
Parker, P. (Primary Investigator), Spicer, J. (Primary Investigator), Ciccarelli, F. (Co-Investigator), Dazzi, F. (Co-Investigator), Farzaneh, F. (Co-Investigator), Hayday, A. (Co-Investigator), Maher, J. (Co-Investigator), Ng, T. (Co-Investigator), Papa, S. (Co-Investigator), Purushotham, A. (Co-Investigator) & Sarker, D. (Co-Investigator)
1/04/2017 → 31/03/2025
Project: Research
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Immunoglobulin E targeted against Folate Receptor alpha for the treatment of triple-negative breast cancer
academic, A. (Primary Investigator), Karagiannis, S. (Co-Investigator), Spicer, J. (Co-Investigator) & Tutt, A. (Co-Investigator)
5/09/2016 → 4/09/2019
Project: Research
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Monitoring the response of the tumour to novel drug combinations
Arnold, J. (Primary Investigator) & Spicer, J. (Co-Investigator)
1/06/2016 → 28/02/2017
Project: Research
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An interdisciplinary approach for elucidating signalling pathways in cancer immunotherapy
Tsoka, S. (Primary Investigator), Karagiannis, S. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/01/2016 → 31/12/2019
Project: Research
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Delineating Signalling Pathways in Cancer Immunotherapy
Tsoka, S. (Primary Investigator), Karagiannis, S. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/12/2015 → 30/11/2018
Project: Research
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Tumour genomic profiling and quantitative detection of circulating biomarkers in patients with non-small cell lung cancer
McCaughan, F. (Primary Investigator) & Spicer, J. (Co-Investigator)
1/10/2015 → 1/10/2018
Project: Research
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Quantitative detection of circulating biomarkers and tumour genomic profiling in patients with non-small cell lung cancer
academic, A. (Primary Investigator), McCaughan, F. (Co-Investigator), Sethi, T. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/10/2015 → 1/10/2018
Project: Research
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Personalised ex-vivo optical proteomics assay to predict treatment response in lung cancer
Santis, G. (Primary Investigator), Ng, T. (Co-Investigator), Ortiz-Zapater, E. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/07/2015 → 30/06/2016
Project: Research
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Development of Novel Antibody Drug Conjugates (ADCs) for the Treatment of Cancer
Karagiannis, S. (Primary Investigator), Rahman, M. (Co-Investigator), Spicer, J. (Co-Investigator) & Thurston, D. (Co-Investigator)
1/07/2015 → 31/03/2016
Project: Research
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In Vivo Generation of Optimal Tumour Antigen-specific Anticancer Immune Responses, by Vaccination with Human Telomerase Reverse Transcriptase (hTERT) Peptides, in Combination with Specific Adjuvants and Elimination of Immunosuppressive Regulatory Cells, in Patients with Advanced Cancer. Phase 1 Study (VAPER)
Spicer, J. (Primary Investigator) & Farzaneh, F. (Co-Investigator)
1/07/2015 → 31/12/2019
Project: Research
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Personalised ex-vivo optical proteomics assay to predict treatment response in lung cancer
Santis, G. (Primary Investigator), Ng, T. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/07/2015 → 30/06/2016
Project: Research
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A Phase 1 dose escalation and pharmacodynamic trial of SGI-110 in combination with pemetrexedand cisplatin chemotherapy
Spicer, J. (Primary Investigator) & Gillett, C. (Co-Investigator)
1/06/2015 → 30/11/2016
Project: Research
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An evaluation of the role of circulating nucleic acid biomarkers in the management of advanced lungcancer
Spicer, J. (Primary Investigator), Goh, V. (Co-Investigator), McCaughan, F. (Co-Investigator) & Sethi, T. (Co-Investigator)
1/06/2015 → 31/05/2018
Project: Research
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A Phase 1 dose escalation and pharmacodynamic trial of SGI-110 in combination with pemetrexed and cisplatin chemotherapy
Spicer, J. (Primary Investigator) & Gillett, C. (Co-Investigator)
1/06/2015 → 30/11/2016
Project: Research
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Phase I study of MOV18, a first in class chimeric IgE antibody against folate receptor-α, in patients with advanced solid tumours: pre-clinical and clinical evaluations.
Karagiannis, S. (Primary Investigator), Spicer, J. (Primary Investigator), Bax, H. (Co-Investigator) & Gillett, C. (Co-Investigator)
1/05/2015 → 31/07/2022
Project: Research
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Preclinical and clinical assay development for CRUK DDO
Spicer, J. (Primary Investigator) & Heck, S. (Co-Investigator)
1/04/2015 → 30/06/2018
Project: Research
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Mechanisms of a tumour specific IgE antibody for ovarian cancer immunotherapy
Bax, H. (Primary Investigator), Josephs, D. (Primary Investigator), Karagiannis, S. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/04/2015 → 1/04/2016
Project: Research
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Phase 1 trial: T4 immunotherapy of head and neck cancer
Maher, J. (Primary Investigator), Papa, S. (Co-Investigator), Peacock, J. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/03/2015 → 1/04/2023
Project: Research
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Pre-Clinical Development of MUC1 and ErbB Dual-Targeting Chimeric Antigen Receptor (CAR) Immunotherapy for Malignant Pleural Mesothelioma (MPM)
Klabatsa, A. (Primary Investigator), Maher, J. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/10/2014 → 30/09/2018
Project: Research
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Intrapleural T4 immunotherapy of malignant pleural mesothelioma
Maher, J. (Primary Investigator) & Spicer, J. (Co-Investigator)
June Hancock Mesothelioma Research Fund
1/05/2014 → 30/04/2017
Project: Research
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Development of immunocyokine-focused and clinically trackable immunotherapy for prostate cancer using genetically enhanced T-cells
Papa, S. (Primary Investigator), Maher, J. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/03/2014 → 28/02/2019
Project: Research
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Novel mechanistic insights into the macrophage-activating functions of a tumour antigen-specific IgE antibody for cancer immunotherapy
Josephs, D. (Primary Investigator), Karagiannis, S. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/03/2014 → 1/03/2018
Project: Research
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Phase 1 trial: T4 immunotherapy of head and neck cancer
Maher, J. (Primary Investigator), Papa, S. (Co-Investigator) & Spicer, J. (Co-Investigator)
2/01/2014 → 1/07/2016
Project: Research
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Development of a comprehensive cell-free DNA biomarker approach for all patients with advanced lung cancer
McCaughan, F. (Primary Investigator), Sethi, T. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/10/2013 → 28/02/2015
Project: Research
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Strengthening the cancer patient immune system
Spicer, J. (Primary Investigator) & Maher, J. (Co-Investigator)
1/10/2013 → 30/09/2016
Project: Research
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Immunotherapy of mesothelioma using dual targeted ErbB and met-specific T-cells
Maher, J. (Primary Investigator) & Spicer, J. (Co-Investigator)
1/09/2012 → 30/09/2015
Project: Research
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Pre-clinical efficacy and safety evaluation of MOv18 IgE, a novel class of antibody targeting alpha folate receptor
Karagiannis, S. (Primary Investigator) & Spicer, J. (Primary Investigator)
1/06/2012 → 31/12/2016
Project: Research
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Experimental Cancer Medicine Centre
Purushotham, A. (Primary Investigator), Spicer, J. (Primary Investigator), Farzaneh, F. (Co-Investigator), Hayday, A. (Co-Investigator), Holmberg, L. (Co-Investigator), Karagiannis, S. (Co-Investigator), Nestle, F. (Co-Investigator), Ng, T. (Co-Investigator), Parker, P. (Co-Investigator), Pinder, S. (Co-Investigator) & Sarker, D. (Co-Investigator)
1/04/2012 → 31/03/2017
Project: Research
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'T4 immunotherapy' of head and neck cancer using genetically engineered T-cells
Maher, J. (Primary Investigator), Farzaneh, F. (Co-Investigator) & Spicer, J. (Co-Investigator)
J P Moulton Charitable Foundation
1/02/2012 → 30/04/2021
Project: Research
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Use of anti-FAP-IL4 to support prostate cancer immunotherapy using PSMA-targeted patient T-cells
Papa, S. (Primary Investigator), Maher, J. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/01/2012 → 30/06/2015
Project: Research
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Mutually assured destruction of breast cancer using genetically targeted T-cells that produce reciprocally supportive cytokines
Maher, J. (Primary Investigator), Antoniou, M. (Co-Investigator), Burchell, J. (Co-Investigator), Harries, M. (Co-Investigator), Lombardi, G. (Co-Investigator), Mullen, G. (Co-Investigator), Purushotham, A. (Co-Investigator), Spicer, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)
6/01/2010 → 5/01/2013
Project: Research
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Pre-clinical efficacy and safety evaluation of MOv18 IgE, a novel class of antibody targeting alpha folate receptor
Spicer, J. (Primary Investigator), Blower, P. (Co-Investigator), Gould, H. (Co-Investigator) & Karagiannis, S. (Co-Investigator)
1/11/2009 → 30/06/2012
Project: Research
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Telephone support and information for self-management of sentinel symptoms in people having chemotherapy for lung cancer: an exploratory trial
Ream, E. (Primary Investigator), Grieve, A. (Co-Investigator), Richardson, A. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/04/2009 → 31/03/2011
Project: Research
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A Comprehensive Cancer Imaging Centre (CCIC)
Blower, P. (Primary Investigator), Ng, T. (Primary Investigator), Ameer-Beg, S. (Co-Investigator), Ellis, P. (Co-Investigator), Goh, V. (Co-Investigator), Green, M. (Co-Investigator), Marsden, P. (Co-Investigator), O'Doherty, M. (Co-Investigator), Pinder, S. (Co-Investigator), Purushotham, A. (Co-Investigator), Schaeffter, T. (Co-Investigator), Spicer, J. (Co-Investigator), T. M. de Rosales, R. (Co-Investigator) & academic, A. (Co-Investigator)
CRUK Cancer Research UK, GSTT Guy's and St Thomas' NHS Foundation Trust
1/10/2008 → 31/03/2023
Project: Research
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Telephone support and information for self-management of tronbusome symptoms in people having chemotherapy for lung cancer.
Ream, E. (Primary Investigator), Richardson, A. (Primary Investigator) & Spicer, J. (Primary Investigator)
1/09/2008 → 31/08/2010
Project: Research
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Studies to demonstrate safety of a novel anticancer strategy using IgE monoclonal antibody
Spicer, J. (Primary Investigator), Gould, H. (Co-Investigator) & Mukherji, D. (Co-Investigator)
1/09/2008 → 31/08/2011
Project: Research
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Signalling Control of CXCR4 Recycling and Ubiquitination: Exploitation for Prognostic Cancer Biomarker Discovery
Ng, T. (Primary Investigator), Ameer-Beg, S. (Co-Investigator), Fruhwirth, G. (Co-Investigator), Gillett, C. (Co-Investigator), Martin Serrano, J. (Co-Investigator) & Spicer, J. (Co-Investigator)
1/04/2008 → 31/03/2013
Project: Research
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Real time imaging of tumour immunotherapy mediated by CEA re-targeted human T-lymphocytes
Maher, J. (Primary Investigator), Mullen, G. (Primary Investigator), Spicer, J. (Primary Investigator) & Blower, P. (Co-Investigator)
1/03/2008 → 28/02/2011
Project: Research
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NIHR Biomedical Research Centre
Afzali, B. (Primary Investigator), Antoniou, M. (Primary Investigator), Barker, J. (Primary Investigator), Barratt, B. (Primary Investigator), Beighton, D. (Primary Investigator), Bevan, S. (Primary Investigator), Blower, P. (Primary Investigator), Burchell, J. (Primary Investigator), Cason, J. (Primary Investigator), Chappell, L. (Primary Investigator), Cope, A. (Primary Investigator), Corrigan, C. (Primary Investigator), Cunninghame Graham, D. (Primary Investigator), Dontu, G. (Primary Investigator), Edgeworth, J. (Primary Investigator), Farzaneh, F. (Primary Investigator), Gee, T. (Primary Investigator), Gould, H. (Primary Investigator), Green, P. (Primary Investigator), Greenough, A. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Hayday, A. (Primary Investigator), Higginson, I. (Primary Investigator), Kalra, L. (Primary Investigator), Karagiannis, S. (Primary Investigator), Kelly, F. (Primary Investigator), Kemper, C. (Primary Investigator), Lau-Walker, M. (Primary Investigator), Lavender, P. (Primary Investigator), Lee, T. (Primary Investigator), Lempp, H. (Primary Investigator), Lewis, C. (Primary Investigator), Lombardi, G. (Primary Investigator), Lord, G. (Primary Investigator), Marber, M. (Primary Investigator), Mason, J. (Primary Investigator), Mathew, C. (Primary Investigator), McGrath, J. (Primary Investigator), Metcalfe, A. (Primary Investigator), Molokhia, M. (Primary Investigator), Mullen, G. (Primary Investigator), Nagel, E. (Primary Investigator), Neil, S. (Primary Investigator), Nestle, F. (Primary Investigator), Oakey, R. (Primary Investigator), Parker, P. (Primary Investigator), Peakman, M. (Primary Investigator), Perera, D. (Primary Investigator), Purushotham, A. (Primary Investigator), Rasekh Ahmadi, K. (Primary Investigator), Rashid, T. (Primary Investigator), Razavi, R. (Primary Investigator), Ridley, A. (Primary Investigator), Robson, M. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Santis, G. (Primary Investigator), Sanz Moreno, V. (Primary Investigator), Sawyer, E. (Primary Investigator), Schaeffter, T. (Primary Investigator), Shah, A. (Primary Investigator), Sharpe, P. (Primary Investigator), Simpson, M. (Primary Investigator), Smith, R. (Primary Investigator), Sorinola, I. (Primary Investigator), Spector, T. (Primary Investigator), Spicer, J. (Primary Investigator), Taams, L. (Primary Investigator), Tavassoli, M. (Primary Investigator), Taylor, D. (Primary Investigator), Tree, T. (Primary Investigator), Trembath, R. (Primary Investigator), Tribe, R. (Primary Investigator), Tutt, A. (Primary Investigator), Waltham, M. (Primary Investigator), Watt, F. (Primary Investigator), Webb, A. (Primary Investigator), Wells, C. (Primary Investigator), Whelan, K. (Primary Investigator), Whitaker, J. (Primary Investigator), Whittlesea, C. (Primary Investigator), Williamson, C. (Primary Investigator), Wolfe, C. (Primary Investigator), Yu, V. (Primary Investigator), academic, A. (Primary Investigator), Hughes, S. (Co-Investigator), Montana, G. (Co-Investigator), Rhode, K. (Co-Investigator), Schnabel, J. (Co-Investigator) & Tziotzios, C. (Co-Investigator)
NIHR National Institute For Health & Care Research, DHSC Department of Health and Social Care
1/04/2007 → 31/03/2017
Project: Research