King's College London

Research portal

Dr Jane Howard

  1. Accepted/In press

    Dominant regulation of long-term allograft survival is mediated by microRNA-142

    Anandagoda, N., Roberts, L. B., Willis, J. C. D., Sarathchandra, P., Xiao, F., Jackson, I., Hertweck, A., Kapoor, P., Jenner, R. G., Howard, J. K. & Lord, G. M., 1 Jan 2020, (Accepted/In press) In : American Journal of Transplantation.

    Research output: Contribution to journalArticle

  2. T-bet controls intestinal mucosa immune responses via repression of type 2 innate lymphoid cell function

    Garrido-Mesa, N., Schroeder, J-H., Stolarczyk, E., Gallagher, A. L., Lo, J. W., Bailey, C., Campbell, L., Sexl, V., Macdonald, T. T., Howard, J. K., Grencis, R. K., Powell, N. & Lord, G. M., Jan 2019, In : Mucosal Immunology. 12, 1, p. 51-63 13 p.

    Research output: Contribution to journalArticle

  3. Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety

    Brooks, L., Viardot, A., Tsakmaki, A., Stolarczyk, E., Howard, J. K., Cani, P. D., Everard, A., Sleeth, M. L., Psichas, A., Anastasovskaj, J., Bell, J. D., Bell-Anderson, K., Mackay, C. R., Ghatei, M. A., Bloom, S. R., Frost, G. & Bewick, G. A., Jan 2017, In : Molecular Metabolism. 6, 1, p. 48-60 13 p.

    Research output: Contribution to journalArticle

  4. Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

    Canavan, J. B., Scottà, C., Vossenkämper, A., Goldberg, R., Elder, M. J., Shoval, I., Marks, E., Stolarczyk, E., Lo, J. W., Powell, N., Fazekasova, H., Irving, P. M., Sanderson, J. D., Howard, J. K., Yagel, S., Afzali, B., MacDonald, T. T., Hernandez-Fuentes, M. P., Shpigel, N. Y., Lombardi, G. & 1 others, Lord, G. M., 9 Mar 2016, In : Gut. 65, 4, p. 584-594 11 p.

    Research output: Contribution to journalArticle

  5. Interleukin 6 increases production of cytokines by colonic innate lymphoid cells in mice and patients with chronic intestinal inflammation

    Powell, N., Lo, J. W., Biancheri, P., Vossenkämper, A., Pantazi, E., Walker, A. W., Stolarczyk, E., Ammoscato, F., Goldberg, R., Scott, P., Canavan, J. B., Perucha, E., Garrido-Mesa, N., Irving, P. M., Sanderson, J. D., Hayee, B., Howard, J. K., Parkhill, J., MacDonald, T. T. & Lord, G. M., 1 Aug 2015, In : Gastroenterology. 149, 2, p. 456-467.e15

    Research output: Contribution to journalArticle

  6. The immune cell transcription factor T-bet: A novel metabolic regulator

    Stolarczyk, E., Lord, G. & Howard, J., Jan 2014, In : Adipocyte. 3, 1, p. 58-62 50 p., N/A.

    Research output: Contribution to journalComment/debate

  7. Improved Insulin Sensitivity despite Increased Visceral Adiposity in Mice Deficient for the Immune Cell Transcription Factor T-bet

    Stolarczyk, E., Vong, C. T., Perucha, E., Jackson, I., Cawthorne, M. A., Wargent, E. T., Powell, N., Canavan, J. B., Lord, G. M. & Howard, J. K., 2 Apr 2013, In : CELL METABOLISM. 17, 4, p. 520-533 14 p.

    Research output: Contribution to journalArticle

  8. LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice

    Archer, A., Stolarczyk, E., Doria, M. L., Helguero, L., Domingues, R., Howard, J. K., Mode, A., Korach Andre, M. & Gustafsson, J-A., 27 Feb 2013, In : Journal of Lipid Research. 54, p. 1300-1311 12 p.

    Research output: Contribution to journalArticle

  9. Genome-wide regulatory analysis reveals that T-bet controls Th17 lineage differentiation through direct suppression of IRF4

    Gökmen, M. R., Dong, R., Kanhere, A., Powell, N., Perucha, E., Jackson, I., Howard, J. K., Hernandez-Fuentes, M., Jenner, R. G. & Lord, G. M., 2013, In : Journal of Immunology. 191, 12, p. 5925-5932 8 p.

    Research output: Contribution to journalArticle

  10. The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor(+) Innate Lymphoid Cells

    Powell, N., Walker, A. W., Stolarczyk, E., Canavan, J. B., Goekmen, M. R., Marks, E., Jackson, I., Hashim, A., Curtis, M. A., Jenner, R. G., Howard, J. K., Parkhill, J., MacDonald, T. T. & Lord, G. M., 19 Oct 2012, In : Immunity. 37, 4, p. 674-684 11 p.

    Research output: Contribution to journalArticle

  11. Absence of CC Chemokine Ligand 2 Does Not Limit Obesity -Associated Infiltration of Macrophages into Adipose Tissue

    Inouye, KE., Shi, H., Howard, JK., Daly, CH., Lord, GM., Rollins, BJ. & Flier, JS., Sep 2007, In : Diabetes. 56, 9, p. 2242-2250 9 p.

    Research output: Contribution to journalArticle

  12. Attenuation of leptin and insulin signaling by SOCS proteins

    Howard, JK. & Flier, JS., Nov 2006, In : TRENDS IN ENDOCRINOLOGY AND METABOLISM. 17, 9, p. 365 - 371 7 p.

    Research output: Contribution to journalArticle

  13. Enhanced Leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells

    Kievit, P., Howard, JK., Badman, MK., Balthasar, N., Coppari, R., Mori, H., Lee, CE., Elmquist, JK., Yoshimura, A. & Flier, JS., Aug 2006, In : CELL METABOLISM. 4, 2, p. 123 - 132 10 p.

    Research output: Contribution to journalArticle

  14. Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3

    Howard, JK., Cave, BJ., Oksanen, LJ., Tzameli, I., Bjorbaek, C. & Flier, JS., Jul 2004, In : Nature Medicine. 10, 7, p. 734 - 738 5 p.

    Research output: Contribution to journalArticle

  15. Leptin prevents the fall in plasma osteocalcin during starvation in male mice

    Goldstone, A. P., Howard, J. K., Lord, G. M., Ghatei, M. A., Gardiner, J. V., Wang, Z. L., Wang, R. M., Girgis, S. I., Bailey, C. J. & Bloom, S. R., 2002, In : Biochemical and Biophysical Research Communications. 295, 2, p. 475 - 481 7 p.

    Research output: Contribution to journalArticle

  16. Visceral adipose tissue and metabolic complications of obesity are reduced in Prader-Willi syndrome female adults: Evidence for novel influences on body fat distribution

    Goldstone, A. P., Thomas, E. L., Brynes, A. E., Bell, J. D., Frost, G., Saeed, N., Hajnal, J. V., Howard, J. K., Holland, A. & Bloom, S. R., Sep 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 9, p. 4330-4338 9 p.

    Research output: Contribution to journalArticle

  17. Requirement for leptin in the induction and progression of autoimmune encephalomyelitis

    Matarese, G., Di Giacomo, A., Sanna, V., Lord, G. M., Howard, J. K., Di Tuoro, A., Bloom, S. R., Lechler, R. I., Zappacosta, S. & Fontana, S., 15 May 2001, In : Journal of Immunology. 166, 10, p. 5909 - 5916 8 p.

    Research output: Contribution to journalArticle

  18. The bioenergetics of the immune system [3]

    Lord, G. M., Matarese, G., Howard, J. K., Lechler, R., Moret, Y. & Schmid-Hempel, P., 4 May 2001, In : Science. 292, 5518, p. 856 1 p.

    Research output: Contribution to journalArticle

  19. Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males

    Matarese, G., Sanna, V., Di Giacomo, A., Lord, G. M., Howard, J. K., Bloom, S. R., Lechler, R. I., Fontana, S. & Zappacosta, S., 2001, In : European Journal of Immunology. 31, 5, p. 1324 - 1332 9 p.

    Research output: Contribution to journalArticle

  20. Increased leptin levels in serum and peritoneal fluid of patients with pelvic endometriosis.[see comment]

    Matarese, G., Alviggi, C., Sanna, V., Howard, J. K., Lord, G. M., Carravetta, C., Fontana, S., Lechler, R. I., Bloom, S. R. & De Placido, G., 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 7, p. 2483 - 2487 5 p.

    Research output: Contribution to journalArticle

  21. Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

    Howard, J., Lord, G., Matarese, G., Vendetti, S., Ghatei, MA., Ritter, MA., Lechler, R. & Bloom, SR., Oct 1999, In : The Journal of clinical investigation. 104, 8, p. 1051 - 1059 9 p.

    Research output: Contribution to journalArticle

  22. Leptin modulates the T-Cell immune response and reverses starvation-induced immunosuppression.

    Lord, GM., Matarese, G., Howard, JK., Baker, RJ., Bloom, SR. & Lechler, RI., 27 Aug 1998, In : NATURE. 394, 6696, p. 897-901 5 p.

    Research output: Contribution to journalArticle

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