Research output per year
Research output per year
Personal profile
Research interests
The Frost Lab is exploring the regulation and function of transposable elements in the human placenta, and their potential role in pregnancy complications. We are part of the Medical and Molecular Genetics department at KCL.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bachelor of Science, Molecular Biology and Biochemistry, Durham University
Master in Science, Human Reproductive Biology, Imperial College London
Doctor of Philosophy, Genomic imprinting, Imperial College London
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Collaborations and top research areas from the last five years
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Dynamics of DNA methylation and its impact on plant embryogenesis
Frost, J. M., Rhee, J. H. & Choi, Y., Oct 2024, In: CURRENT OPINION IN PLANT BIOLOGY. 81, 102593.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
The evolving genetic landscape of telomere biology disorder dyskeratosis congenita
Tummala, H., Walne, A. J., Badat, M., Patel, M., Walne, A. M., Alnajar, J., Chow, C. C., Albursan, I., Frost, J. M., Ballard, D., Killick, S., Szitányi, P., Kelly, A. M., Raghavan, M., Powell, C., Raymakers, R., Todd, T., Mantadakis, E., Polychronopoulou, S. & Pontikos, N. & 5 others, , 14 Oct 2024, In: EMBO Molecular Medicine. 16, 10, p. 2560-2582 23 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Distinct regulatory pathways contribute to dynamic CHH methylation patterns in transposable elements throughout Arabidopsis embryogenesis
Lee, J., Lee, S., Park, K., Shin, S. Y., Frost, J. M., Hsieh, P. H., Shin, C., Fischer, R. L., Hsieh, T. F. & Choi, Y., 2023, In: Frontiers in plant science. 14, 1204279.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Regulation of human trophoblast gene expression by endogenous retroviruses
Frost, J. M., Amante, S. M., Okae, H., Jones, E. M., Ashley, B., Lewis, R. M., Cleal, J. K., Caley, M. P., Arima, T., Maffucci, T. & Branco, M. R., Apr 2023, In: NATURE STRUCTURAL AND MOLECULAR BIOLOGY. 30, 4, p. 527-538 12 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Citations (Scopus) -
Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation
Cheng, K. C. L., Frost, J. M., Sánchez-Luque, F. J., García-Canãdas, M., Taylor, D., Yang, W. R., Irayanar, B., Sampath, S., Patani, H., Agger, K., Helin, K., Ficz, G., Burns, K. H., Ewing, A., García-Pérez, J. L. & Branco, M. R., Dec 2023, In: Epigenetics and Chromatin. 16, 1, 39.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)