Research output per year
Research output per year
Personal profile
Research interests
Regulation of pulmonary vascular tone and airways smooth muscle constriction; beta adrenoceptor- and nitric oxide-mediated relaxation of pulmonary arteries; pathophysiologic mechansims of hypoxic vasomotor responses; vascular effects of sphingolipids; smooth muscle signalling pathways, ion channels and calcium sensitisation; asthma and airway smooth muscle function.
Research interests (short)
Regulation of pulmonary vascular tone; regulation of airways smooth muscle.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Similar Profiles
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Phenotype and Functional Features of Human Telomerase Reverse Transcriptase Immortalized Human Airway Smooth Muscle Cells from Asthmatic and Non-Asthmatic Donors
Burgess, J. K., Ketheson, A., Faiz, A., Limbert Rempel, K. A., Oliver, B. G., Ward, J. P. T. & Halayko, A. J., 16 Jan 2018, (E-pub ahead of print) In: Scientific Reports. 8, 1, 805.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)140 Downloads (Pure) -
Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries
Prieto-Lloret, J., Snetkov, V., Shaifta, Y. M., Docio, I., Connolly, M., MacKay, C. E., Knock, G. A., Ward, J. P. T. & Aaronson, P. I., Apr 2018, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 4, p. L670-L685Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)224 Downloads (Pure) -
Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1
Shaifta, Y., MacKay, C. E., Irechukwu, N. I., O'Brien, K., Wright, D. B., Ward, J. P. T. & Knock, G. A., 1 Jan 2018, In: The Journal of Physiology. 595, 1, p. 47-66Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)176 Downloads (Pure) -
From physiological redox signalling to oxidant stress
Ward, J. P. T., 18 Oct 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 967. p. 335-342 8 p. (Advances in Experimental Medicine and Biology; vol. 967).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
10 Citations (Scopus) -
ROS-dependent activation of RhoA/Rho-kinase in pulmonary artery: Role of Src-family kinases and ARHGEF1
MacKay, C. E., Shaifta, Y., Snetkov, V. V., Francois, A. A., Ward, J. P. T. & Knock, G. A., Sept 2017, In: Free Radical Biology and Medicine. 110, p. 316-331Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)257 Downloads (Pure)
Projects
- 29 Finished
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Development of a novel therapeutic for inflammatory lung disorders
1/01/2016 → 31/12/2019
Project: Research
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Src as a key mediator of multiple oxidant signalling pathways in vascular smooth muscle
1/01/2013 → 31/12/2015
Project: Research
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B-catenin as a novel mediator of nitric oxide-regulated gene transcription in vascular endothelium
1/06/2012 → 31/08/2015
Project: Research
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Role of SERCA-2 in airway remodelling in hyperresponsiveness in asthma
1/10/2011 → 31/05/2013
Project: Research
Activities
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Experimental Physiology (Journal)
Jeremy Ward (Editor)
2013 → …Activity: Publication peer-review and editorial work › Editorial activity
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Physiology Reports (Journal)
Jeremy Ward (Editorial board member)
2013 → …Activity: Publication peer-review and editorial work › Editorial activity
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Nominating Committee for the International Union of Physiological Sciences Congress
Jeremy Ward (Member)
2013Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
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PULMONARY PHARMACOLOGY AND THERAPEUTICS (Journal)
Jeremy Ward (Editor)
2008 → 2013Activity: Publication peer-review and editorial work › Editorial activity
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Policy Committee and member of Executive
Jeremy Ward (Chair)
2007 → 2012Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups