Research output per year
Research output per year
Personal profile
Biographical details
Jernej obtained his BSc in Molecular Biology from the University of Ljubljana, Slovenia in 1999, and PhD and short postdoc with Bob Darnell at the Rockefeller University, New York, during 2000-2006.
Jernej started his research group at the MRC Laboratory of Molecular Biology in Cambridge in July 2006, in April 2013, the group moved to the Queen Square UCL Institute of Neurology in London, and in August 2016 was seconded to The Francis Crick Institute.
In 2020, Jernej started a satellite team at the Institute of Chemistry in Ljubljana funded by ERC advanced grant.
Jernej is an EMBO fellow and member of London RNA club.
In April 2022, Jernej was appointed as UK DRI Centre Director at King's College London based at the Maurice Wohl Clinical Neuroscience Institute.
Research interests (short)
RNA biology and the role of RNA in neurodegenerative diseases.
Development of techniques that integrate biochemistry and computational biology to obtain a comprehensive map of interactions between proteins and their RNA partners within cells.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Group Leader , Natl Inst Chem, National Institute of Chemistry - Slovenia
20 Jan 2020 → 31 Oct 2024
Seconded Group Leader , Francis Crick Institute
16 Aug 2016 → 30 Sept 2022
Professor of Molecular Neuroscience
1 Apr 2013 → 31 Mar 2022
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Collaborations and top research areas from the last five years
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A computationally-enhanced hiCLIP atlas reveals Staufen1 RNA binding features and links 3'UTR structure to RNA metabolism
Ule, J., Chakrabarti, A. M., Lee, F. C. Y., Luscombe, N. M. & Iosub, I., 1 Jan 2022, Cold Spring Harbor Laboratory Press.Research output: Working paper/Preprint › Preprint
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CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1
Hluchý, M., Gajdušková, P., Ruiz de los Mozos, I., Rájecký, M., Kluge, M., Berger, B. T., Slabá, Z., Potěšil, D., Weiß, E., Ule, J., Zdráhal, Z., Knapp, S., Paruch, K., Friedel, C. C. & Blazek, D., 22 Sept 2022, In: Nature. 609, 7928, p. 829-834 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)120 Downloads (Pure) -
Identifying ribosome heterogeneity using ribosome profiling
Alkan, F., Wilkins, O. G., Hernández-Pérez, S., Ramalho, S., Silva, J., Ule, J. & Faller, W. J., 9 Sept 2022, In: Nucleic Acids Research. 50, 16, p. e95Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)31 Downloads (Pure) -
m6A reader Pho92 is recruited co-transcriptionally and couples translation efficacy to mRNA decay to promote meiotic fitness in yeast
Ule, J., Varier, R. A., Sideri, T., Capitanchik, C., Manova, Z., Calvani, E., Rossi, A., Edupuganti, R., Ensinck, I., Chan, V. W. C., Patel, H., Kirkpatrick, J., Faull, P. A., Snijders, A. P., Vermeulen, M., Ralser, M., Luscombe, N. M. & van Werven, F. J., 1 Jan 2022, Cold Spring Harbor Laboratory Press.Research output: Working paper/Preprint › Preprint
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Positional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP
Kuret, K., Amalietti, A. G., Jones, D. M., Capitanchik, C. & Ule, J., Dec 2022, In: Genome biology. 23, 1, 191.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus)
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DRI-PRO20232: Capturing the regulatory RNA-binding proteins on Camk2a and Mapt
UKDRI UK Dementia Research Institute
1/12/2023 → 30/11/2024
Project: Research
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MRC World Class Labs Capital Funding 2023/24 King's DRI
UKDRI UK Dementia Research Institute
1/11/2023 → 31/03/2024
Project: Research
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UK DRI QQ2: UK Dementia Research Institute Centre Award QQ2
Ule, J., Marzi, S., Mizielinska, S., Ruepp, M. & Shaw, C.
UKDRI UK Dementia Research Institute
1/04/2023 → 31/03/2028
Project: Research
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Therapeutic modulation of feedback loops to counteract the molecular TDP-43 pathogenesis
Motor Neurone Disease Association
1/12/2022 → 30/11/2025
Project: Research
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Grant transf: RNA-scaffolded RNP condensation, its physiologic regulation, and therapeutic modulation
1/04/2022 → 31/12/2024
Project: Research
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EMBO European Molecular Biology Organisation (External organisation)
Jernej Ule (Member)
1 Jan 2017 → 31 Dec 2021Activity: Membership › Membership of committee
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EMBO European Molecular Biology Organisation (External organisation)
Jernej Ule (Member)
1 Jan 2016Activity: Membership › Membership of network
Prizes
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Person of the Year 2019
Ule, Jernej (Recipient), 1 Jan 2019
Prize: Prize (including medals and awards)
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RNA society mid-career award 2020
Ule, Jernej (Recipient), 6 Dec 2019
Prize: Prize (including medals and awards)