Research output per year
Research output per year
Personal profile
Research interests
Application of human genetics to the study of neurological and psychiatric disorders; in particular the neurological disorders, Alzheimer's disease and motor neurone disease and the psychiatric disorders schizophrenia and autism.
Research interests (short)
Molecular genetics of psychiatric and neurodegenerative disorders
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of Oxford
Award Date: 1 Jan 1978
Bachelor of Arts, University of Oxford
Award Date: 1 Jan 1974
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Indonesia Schizophrenia Consortium, PsychENCODE, Psychosis Endophenotypes International Consortium, SynGO Consortium & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 21 Apr 2022, In: Nature. 604, 7906, p. 502-508 7 p.Research output: Contribution to journal › Article › peer-review
Open Access161 Citations (Scopus) -
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Nov 2021, In: Biological psychiatry. 90, 9, p. 611-620 10 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study
Thygesen, J. H., Presman, A., Harju-seppänen, J., Irizar, H., Jones, R., Kuchenbaecker, K., Lin, K., Alizadeh, B. Z., Austin-zimmerman, I., Bartels-velthuis, A., Bhat, A., Bruggeman, R., Cahn, W., Calafato, S., Crespo-facorro, B., De Haan, L., De Zwarte, S. M. C., Di Forti, M., Díez-revuelta, Á., Hall, J., & 37 others, 1 Sept 2021, In: Molecular Psychiatry. 26, 9, p. 5307-5319Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer’s disease
Ashton, N. J., Nevado-Holgado, A. J., Barber, I. S., Lynham, S., Gupta, V. B., Chatterjee, P., Goozee, K., Hone, E., Pedrini, S., Blennow, K., Schöll, M., Zetterberg, H., Ellis, K. A., Bush, A. I., Rowe, C., Villemagne, V. L., Ames, D., Masters, C. L., Aarsland, D., Powell, J. F., & 3 others, 6 Feb 2019, In: Science Advances. 5, 2, eaau7220.Research output: Contribution to journal › Article › peer-review
Open Access42 Citations (Scopus) -
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease
Baker, E., Sims, R., Leonenko, G., Frizzati, A., Harwood, J. C., Grozeva, D., Morgan, K., Passmore, P., Holmes, C., Powell, J., Brayne, C., Gill, M., Mead, S., Bossù, P., Spalletta, G., Goate, A. M., Cruchaga, C., Maier, W., Heun, R., Jessen, F., & 16 others, 1 Jul 2019, In: PLoS ONE. 14, 7, e0218111.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus)
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Deciphering the causal relationship between blood metabolic biomarkers and Alzheimer's Disease
Proitsi, P., Dobson, R., Legido Quigley, C. & Powell, J.
1/03/2017 → 30/09/2023
Project: Research
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A genetic study of phenotypic modifiers in C9orf72 gene repeat expansions carriers
Shaw, C., Powell, J. & Fogh, I.
Motor Neurone Disease Association
1/01/2019 → 31/12/2021
Project: Research
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Progression of Alzheimer's disease, frailty and dysbiosis: Metagenomic and metabolomic analysis
Powell, J., Proitsi, P. & Steves, C.
1/01/2018 → 31/12/2020
Project: Research
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Progression of Alzheimer's disease, frailty and dysbiosis: Metagenomic and metabolomic analysis
Powell, J., Morgan, P. & Steves, C.
1/01/2018 → 31/12/2020
Project: Research