Search results

• Active

  Development of Novel 18F-labelled Molecular Probes for Long-Term CAR T-cell Tracking with Positron Emission Tomography (CART_PET)

  Yan, R. (Primary Investigator), Arnold, J. (Co-Investigator) & Maher, J. (Co-Investigator)

  CRUK Cancer Research UK

  1/12/2023 → 30/11/2026

  Project: Research

• Finished

  CARiMs: Development of chimeric antigen receptor-iPS-derived macrophages (CARiMs)

  Apolonia, L. (Primary Investigator) & Maher, J. (Co-Investigator)

  MRC Medical Research Council

  1/02/2022 → 31/03/2023

  Project: Research

• Assessing a flexible, one-step, gene-editing platform for CAR T-cells

  Davies, D. (Primary Investigator) & Maher, J. (Co-Investigator)

  KHP King's Health Partners

  20/05/2020 → 31/03/2021

  Project: Research

• Immunotherapy of head and neck cancer using T4 CAR T-cells potentiated by lymphodepletion and nivolumab

  Maher, J. (Primary Investigator), Papa, S. (Co-Investigator), Spicer, J. (Co-Investigator) & Reid, F. (Co-Investigator)

  J P Moulton Charitable Foundation

  2/01/2020 → 31/12/2023

  Project: Research

• Immunotherapy for malignant mesothelioma using IL-6-neutralising CAR T-cells

  Maher, J. (Primary Investigator), Davies, D. (Co-Investigator) & Hull, C. (Co-Investigator)

  Asthma and Lung UK

  1/03/2019 → 28/02/2021

  Project: Research

• CAR T-cell mediated co-targeting of MUC1 and HER2 to achieve precision immunotherapy of breast cancer

  Maher, J. (Primary Investigator) & Burchell, J. (Co-Investigator)

  Breast Cancer Now

  2/01/2019 → 10/08/2022

  Project: Research

• Combination immunotherapy for solid tumours with oncolytic virus & cognate CAR T-cells

  Maher, J. (Primary Investigator) & Ajina, A. (Co-Investigator)

  MRC Medical Research Council

  1/10/2017 → 30/06/2021

  Project: Research

• KHP Centre Award - Non-Clinical Training Award

  Parker, P. (Primary Investigator), Spicer, J. (Primary Investigator), Ciccarelli, F. (Co-Investigator), Dazzi, F. (Co-Investigator), Farzaneh, F. (Co-Investigator), Hayday, A. (Co-Investigator), Maher, J. (Co-Investigator), Ng, T. (Co-Investigator), Papa, S. (Co-Investigator), Purushotham, A. (Co-Investigator) & Sarker, D. (Co-Investigator)

  CRUK Cancer Research UK

  1/04/2017 → 31/03/2025

  Project: Research

  • Awards 100%
  • Training 80%
  • Award 20%

• NIHR Biomedical Research Centre. Funding for Financial Years 2017/18, 2018/19

  Wolfe, C. (Primary Investigator), Parsons, M. (Primary Investigator), Gould, H. (Primary Investigator), Corrigan, C. (Primary Investigator), Greenough, A. (Primary Investigator), Peakman, M. (Primary Investigator), Vyse, T. (Primary Investigator), Antoniou, M. (Primary Investigator), Oakey, R. (Primary Investigator), McGrath, J. (Primary Investigator), Karagiannis, S. (Primary Investigator), Barker, J. (Primary Investigator), Flohr, C. (Primary Investigator), Tziotzios, C. (Primary Investigator), Whittaker, S. (Primary Investigator), Spector, T. (Primary Investigator), Watt, F. (Primary Investigator), Hayday, A. (Primary Investigator), Spencer, J. (Primary Investigator), Cope, A. (Primary Investigator), Malim, M. (Primary Investigator), Martin Serrano, J. (Primary Investigator), Edgeworth, J. (Primary Investigator), Cason, J. (Primary Investigator), Lord, G. (Primary Investigator), Dorling, A. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Lombardi, G. (Primary Investigator), Ostermann, M. (Primary Investigator), Shah, A. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Wells, C. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Sawyer, E. (Primary Investigator), Maher, J. (Primary Investigator), Daniels, R. T. (Primary Investigator), Ilic, D. (Primary Investigator), Poston, L. (Primary Investigator), Rutherford, M. (Primary Investigator), Gee, T. (Primary Investigator), Blower, P. (Primary Investigator), Edwards, D. (Primary Investigator), Sharpe, P. (Primary Investigator), Streit, A. (Primary Investigator), Naglik, J. (Primary Investigator), Tavassoli, M. (Primary Investigator) & McNaughton, P. (Primary Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2017 → 31/03/2022

  Project: Research

  • Biomedical Research 100%

• Immunotherapy for mesothelioma using ErbB re-targeted CAR T-cells in combination with PD-1 checkpoint inhibition

  Maher, J. (Primary Investigator), Davies, D. (Co-Investigator) & Spicer, J. (Co-Investigator)

  Asthma and Lung UK

  1/04/2017 → 31/05/2020

  Project: Research

• Harnessing parallel (p)CAR technology to target T-cells against tumour-associated MUC1

  Maher, J. (Primary Investigator), Burchell, J. (Co-Investigator) & Owen, D. (Co-Investigator)

  1/01/2017 → 31/12/2019

  Project: Research

• Combinatory αvβ6 integrin -targeted nanomedicines and immunotherapy for breast cancer therapy

  Al-Jamal, K. (Primary Investigator), Maher, J. (Co-Investigator) & Marshall, J. (Co-Investigator)

  1/01/2017 → 31/12/2019

  Project: Research

• Pharmaco-immunotherapy of triple negative breast cancer using Vγ9Vδ2 Tcellslsand liposomal encapsulated drugs

  Maher, J. (Primary Investigator), Parente Pereira, A. (Co-Investigator), T. M. de Rosales, R. (Co-Investigator) & Tutt, A. (Co-Investigator)

  MRC Medical Research Council

  1/11/2016 → 31/08/2017

  Project: Research

• Development of CAR T-cell immunotherapy

  Maher, J. (Primary Investigator)

  1/10/2016 → 30/09/2018

  Project: Research

• In vivo tracking of therapeutic cells with dual nuclear and fluorescence imaging

  Yan, R. (Primary Investigator) & Maher, J. (Co-Investigator)

  Rosetrees Trust

  1/07/2016 → 31/12/2020

  Project: Research

• Integrating imaging into immunotherapy - developing PET traceable CAR T-cells

  Fruhwirth, G. (Primary Investigator), Lombardi, G. (Co-Investigator) & Maher, J. (Co-Investigator)

  Worldwide Cancer Research

  1/07/2016 → 14/09/2018

  Project: Research

• Engineering avb6-targeted fourth generation chimeric antigen receptor (CAR) T-cells for immunotherapy of pancreaticductal adenocarcinoma (PDAC).

  Maher, J. (Primary Investigator), Sarker, D. (Co-Investigator) & Whilding, L. (Co-Investigator)

  1/06/2016 → 31/05/2018

  Project: Research

• Engineering αvβ6-targeted fourth generation chimeric antigen receptor (CAR) T-cells for immunotherapy of pancreatic ductal adenocarcinoma.

  Maher, J. (Primary Investigator), Sarker, D. (Co-Investigator) & Whilding, L. (Co-Investigator)

  1/06/2016 → 31/05/2018

  Project: Research

• Improving Efficacy and Reducing Toxicity of Chimeric Antigen Receptor Driven Immunotherapy for Prostate Cancer

  Papa, S. (Primary Investigator) & Maher, J. (Co-Investigator)

  1/05/2016 → 1/05/2019

  Project: Research

• Development and evaluation of chimeric antigen receptor T cells (CAR-T Cells) for treatment of cancers

  Maher, J. (Primary Investigator)

  British Council

  1/04/2016 → 31/03/2017

  Project: Research

• Engineering avß6-targeted fourth generation chimeric antigen receptor (CAR) T-cells for immunotherapy of pancreatic ductal adenocarcinoma

  Maher, J. (Primary Investigator), Sarker, D. (Co-Investigator) & Whilding, L. (Co-Investigator)

  CRUK Cancer Research UK

  1/02/2016 → 31/07/2019

  Project: Research

• Integrating medical imaging into cancer immunotherapy: Development of clinically traceable CAR and GammaDelta T-cells

  Blower, P. (Primary Investigator), Fruhwirth, G. (Primary Investigator), Maher, J. (Primary Investigator) & T. M. de Rosales, R. (Primary Investigator)

  CRUK Cancer Research UK

  1/01/2016 → 30/11/2019

  Project: Research

• Advancing the UCOE-based gene expression platform for improved biomanufacturing and gene therapy applications

  Antoniou, M. (Primary Investigator) & Maher, J. (Co-Investigator)

  EMD Millipore Corporation

  1/10/2015 → 30/09/2019

  Project: Research

• Combinatory αvβ6 integrin -targeted nanomedicines and immunotherapy for pancreatic cancer therapy

  Al-Jamal, K. (Primary Investigator) & Maher, J. (Co-Investigator)

  1/09/2015 → 30/08/2016

  Project: Research

• Combinatory αvβ6 integrin -targeted nanomedicines and immunotherapy for pancreatic cancer therapy

  Al-Jamal, K. (Primary Investigator) & Maher, J. (Co-Investigator)

  1/09/2015 → 31/08/2016

  Project: Research

• Integrating imaging into Immunotherapy - Developing in vivo traceable CAR T-cells

  Fruhwirth, G. (Primary Investigator), Lombardi, G. (Co-Investigator) & Maher, J. (Co-Investigator)

  1/08/2015 → 31/01/2017

  Project: Research

• Improving Efficacy and Reducing Toxicity of Chimeric Antigen Receptor Driven Immunotherapy for Prostate Cancer

  Papa, S. (Primary Investigator), Chowdhury, S. (Co-Investigator) & Maher, J. (Co-Investigator)

  1/07/2015 → 1/07/2019

  Project: Research

• Immunotherapy of pancreatic cancer using avB6 targeted chimeric antigen receptor (CAR) T-cells

  Maher, J. (Primary Investigator), Sarker, D. (Co-Investigator) & Whilding, L. (Co-Investigator)

  MRC Medical Research Council

  1/06/2015 → 31/05/2016

  Project: Research

• Integrating imaging into Immunotherapy - Developing in vivo traceable CAR T-cells

  Fruhwirth, G. (Primary Investigator), Lombardi, G. (Co-Investigator) & Maher, J. (Co-Investigator)

  KHP King's Health Partners

  1/04/2015 → 7/07/2016

  Project: Research

• Modulation of tumoural TNF and IFN-y signalling to permit efficient immunotherapy for the treatment of breast cancer

  Arnold, J. (Primary Investigator) & Maher, J. (Co-Investigator)

  1/04/2015 → 31/03/2018

  Project: Research

• Phase 1 trial: T4 immunotherapy of head and neck cancer

  Maher, J. (Primary Investigator), Papa, S. (Co-Investigator), Peacock, J. (Co-Investigator) & Spicer, J. (Co-Investigator)

  Wellcome Trust

  1/03/2015 → 1/04/2023

  Project: Research

• Is the F-actin-binding protein drebrin important for prostatic cancer cell metastasis?

  Gordon-Weeks, P. (Primary Investigator) & Maher, J. (Co-Investigator)

  15/02/2015 → 14/08/2015

  Project: Research

• Immunotherapy of Epithelial Ovarian Cancer using Autologous Gamma Delta T-cells

  Maher, J. (Primary Investigator) & Parente Pereira, A. (Co-Investigator)

  MRC Medical Research Council

  1/12/2014 → 30/04/2017

  Project: Research

• Development of gamma delta (gd) T-cell immunotherapy for triple negative breast cancer (TNBC)

  Maher, J. (Primary Investigator), Parente Pereira, A. (Co-Investigator) & Tutt, A. (Co-Investigator)

  CRUK Cancer Research UK

  1/11/2014 → 31/01/2017

  Project: Research

• Pre-Clinical Development of MUC1 and ErbB Dual-Targeting Chimeric Antigen Receptor (CAR) Immunotherapy for Malignant Pleural Mesothelioma (MPM)

  Klabatsa, A. (Primary Investigator), Maher, J. (Co-Investigator) & Spicer, J. (Co-Investigator)

  1/10/2014 → 30/09/2018

  Project: Research

• Maximising the therapeutic index of CAR T-cell immunotherapy of breast cancer

  Maher, J. (Primary Investigator)

  Breast Cancer Campaign

  1/10/2014 → 30/09/2015

  Project: Research

• Evaluation of vulval tumour avB6 integrin expression

  Maher, J. (Primary Investigator)

  GRACE

  10/09/2014 → 9/09/2016

  Project: Research

• Immonocytokine targeted CAR T-cell immunotherapy of breast cancer

  Maher, J. (Primary Investigator), Burchell, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2014 → 30/06/2015

  Project: Research

• Setting the threshold to target HER2 positive breast cancer using chimeric antigen receptor engineered T-cells

  Maher, J. (Primary Investigator) & Morris, J. (Co-Investigator)

  Breast Cancer Campaign

  1/07/2014 → 30/09/2017

  Project: Research

• Intrapleural T4 immunotherapy of malignant pleural mesothelioma

  Maher, J. (Primary Investigator) & Spicer, J. (Co-Investigator)

  June Hancock Mesothelioma Research Fund

  1/05/2014 → 30/04/2017

  Project: Research

• Development of immunocyokine-focused and clinically trackable immunotherapy for prostate cancer using genetically enhanced T-cells

  Papa, S. (Primary Investigator), Maher, J. (Co-Investigator) & Spicer, J. (Co-Investigator)

  1/03/2014 → 28/02/2019

  Project: Research

• Phase 1 trial: T4 immunotherapy of head and neck cancer

  Maher, J. (Primary Investigator), Papa, S. (Co-Investigator) & Spicer, J. (Co-Investigator)

  2/01/2014 → 1/07/2016

  Project: Research

• Strengthening the cancer patient immune system

  Spicer, J. (Primary Investigator) & Maher, J. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Pre-emptive immune therapy to prevent relapse of myeloid malignancies

  Barber, L. (Primary Investigator), Farzaneh, F. (Primary Investigator), Lombardi, G. (Co-Investigator), Maher, J. (Co-Investigator), Mufti, G. (Co-Investigator) & So, E. (Co-Investigator)

  Blood Cancer UK

  1/08/2013 → 31/12/2017

  Project: Research

• Immunotherapy of pancreatic cancer using chimeric antigen receptor engrafted T-cells targeted against the avß6 integrin

  Maher, J. (Primary Investigator)

  1/06/2013 → 31/05/2014

  Project: Research

• Immunotherapy of pancreatic cancer using chimeric antigen receptor engrafted T-cells targeted against the avß6 integrin

  Maher, J. (Primary Investigator)

  Pancreatic Cancer UK

  1/06/2013 → 31/08/2014

  Project: Research

• Prostate cancer immunotherapy using PSMA-targeted IL-4-responsive T-cells

  Maher, J. (Primary Investigator), Chowdhury, S. (Co-Investigator), Mullen, G. (Co-Investigator) & Papa, S. (Co-Investigator)

  Worldwide Cancer Research

  1/06/2013 → 30/11/2015

  Project: Research

• Pharmaco-immunotherapy of ovarian cancer using T-cells and targeted liposomal amino-bisphosphonates

  Maher, J. (Primary Investigator)

  KHP King's Health Partners

  1/02/2013 → 30/04/2014

  Project: Research

• Prostate specific membrane antigen targeting gene modified adoptive immunotherapy utilising a novel tumour stroma binding immunocytokine T-cell cytotoxicity and longevity

  Papa, S. (Primary Investigator) & Maher, J. (Co-Investigator)

  Prostate Cancer UK

  1/11/2012 → 31/10/2015

  Project: Research

• Pharmaco-immunotherapy of ovarian cancer using gamma delta T-cells and targeted liposomal amino-bisphosphonates

  Maher, J. (Primary Investigator)

  1/10/2012 → 30/09/2014

  Project: Research