Research output per year
Research output per year
Personal profile
Research interests
Molecular basis of inherited skin disorders: discovering genes for specific diseases, understanding disease mechanisms and determining relevance to diseased and healthy skin; translational research therapies - developing new gene, protein, cell and drug therapies for patients with inherited skin diseases such as epidermolysis bullosa (inherited skin fragility); prenatal diagnosis - development of preimplantation genetic haplotyping for severe inherited skin diseases
Research interests (short)
Molecular basis of inherited skin disorders; translational research therapies; prenatal diagnosis
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Non-Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First-In-Class IgE Antibody Recognising Folate Receptor Alpha
Stavraka, C., Chauhan, J., Crescioli, S., McSweeney, S. M., Pope, A., Gillett, C., Di Meo, A., Prassas, I., Laddach, R., Stoker, K., McCraw, A. J., Adams, R., Tull, T. J., Naban, N., Willsmore, Z., Semkova, K. V., Grattan, C. E. H., McGrath, J., Till, S. J. & Corrigan, C. J. & 9 others, , 6 Mar 2025, (E-pub ahead of print) In: Allergy. 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Downloads (Pure) -
Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa
Mustfa, S. A., Dimitrievska, M., Wang, C., Gu, C., Sun, N., Romańczuk, K., Karpinski, P., Łaczmański, Ł., McGrath, J. A., Jacków‐Malinowska, J. & Chiappini, C., 12 Mar 2025, (E-pub ahead of print) In: ADVANCED MATERIALS.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Downloads (Pure) -
Costs of UK community care for individuals with recessive dystrophic epidermolysis bullosa: Findings of the Prospective Epidermolysis Bullosa Longitudinal Evaluation Study
Jeffs, E., Pillay, E., Ledwaba-Chapman, L., Bisquera, A., Robertson, S., McGrath, J., Wang, Y., Martinez, A., Patel, A. & Mellerio, J. E., Feb 2024, In: Skin Health and Disease. 4, 1, e314.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)109 Downloads (Pure) -
Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria
McSweeney, S. M., Saklatvala, J., Rispoli, R., Ganier, C., Woszczek, G., Thomas, L., Hveem, K., Løset, M., Dand, N., Tziotzios, C., Simpson, M. & McGrath, J. A., Feb 2024, In: Journal of Allergy and Clinical Immunology. 153, 2, p. 521-526.e11Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)39 Downloads (Pure) -
Highly efficient biallelic correction of homozygous COL7A1 mutation using ABE8e adenine base editor
Brooks, I. R., Alrokh, Y., Kazemizadeh, A., Balon, K., Newby, G., Liu, D. R., Łaczmański, Ł., McGrath, J. A. & Jacków-Malinowska, J., Apr 2024, In: British Journal of Dermatology. 190, 4, p. 583-585 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Citation (Scopus)
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Development and testing of gene editing for epidermolytic ichthyosis
McGrath, J. (Primary Investigator) & Jackow, J. (Co-Investigator)
1/02/2025 → 31/01/2028
Project: Research
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Genomic and lipidomic approaches to identify therapeutic targets in solar urticaria
McGrath, J. (Primary Investigator), Dand, N. (Co-Investigator), Simpson, M. (Co-Investigator) & academic, A. (Co-Investigator)
EADV European Academy of Dermatology and Venereology
1/01/2025 → 30/09/2026
Project: Research
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Investigation of lipid-mediated disease mechanisms underpinning solar urticaria
McGrath, J. (Primary Investigator), Jackow, J. (Co-Investigator) & McSweeney, S. (Co-Investigator)
1/09/2024 → 31/08/2025
Project: Research
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Genotype-phenotype correlation to identify lipid-mediated pathogenic mechanisms in solar urticaria
McGrath, J. (Primary Investigator)
15/06/2024 → 1/09/2026
Project: Research
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Investigating the role of marginal zone B cells in the pathogenesis of pemphigus vulgaris
Tull, T. (Primary Investigator) & McGrath, J. (Co-Investigator)
6/05/2024 → 5/05/2029
Project: Research