Research output per year
Research output per year
- 23 results
Search results
-
2020
Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement
Brayson, D., Holohan, S. J., Bardswell, S. C., Arno, M., Lu, H., Jensen, H. K., Tran, P. K., Barallobre-Barreiro, J., Mayr, M., Dos Remedios, C. G., Tsang, V. T., Frigiola, A. & Kentish, J. C., 18 Aug 2020, In: Journal of the American Heart Association. 9, 16, p. e015342Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
The right ventricle of Tetralogy of Fallot patients undergoing pulmonary valve replacement has normal myofilament function but shows perturbations to the expression of extracellular matrix genes
Brayson, D., Holohan, S.-J., Bardswell, S. C., Arno, M., Lu, H., Jensen, H. K., Kiet Tran, P., Barallobre-Barreiro, J., Mayr, M., G.dos Remedios, C., T. Tsang, V., Frigiola, A. & Kentish, J., 28 May 2020, (Accepted/In press) In: Journal of the American Heart Association.Research output: Contribution to journal › Article › peer-review
Open AccessFile162 Downloads (Pure) -
2018
Monophosphorylation of cardiac troponin-I at Ser23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis
Martin-garrido, A., Biesiadecki, B. J., Salhi, H. E., Shaifta, Y., Dos Remedios, C. G., Ayaz-guner, S., Cai, W., Ge, Y., Avkiran, M. & Kentish, J. C., 1 Jun 2018, In: Journal of Biological Chemistry. 293, 22, p. 8588-8599Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)244 Downloads (Pure) -
2017
A model of cardiac contraction based on novel measurements of tension development in human cardiomyocytes
Land, S., Park-Holohan, S. J., Smith, N. P., dos Remedios, C. G., Kentish, J. C. & Niederer, S. A., 1 May 2017, In: Journal of Molecular and Cellular Cardiology. 106, 0, p. 68-83 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile104 Citations (Scopus)680 Downloads (Pure) -
Reduced First-Phase Ejection Fraction and Sustained Myocardial Wall Stress in Hypertensive Patients with Diastolic Dysfunction: A Manifestation of Impaired Shortening Deactivation That Links Systolic to Diastolic Dysfunction and Preserves Systolic Ejection Fraction
Gu, H., Li, Y., Fok, H., Simpson, J., Kentish, J., Shah, A. & Chowienczyk, P., 1 Apr 2017, In: Hypertension. 69, 4, p. 633-640 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)135 Downloads (Pure) -
2012
Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice
Fraysse, B., Weinberger, F., Bardswell, S. C., Cuello, F., Vignier, N., Geertz, B., Starbatty, J., Kraemer, E., Coirault, C., Eschenhagen, T., Kentish, J. C., Avkiran, M. & Carrier, L., Jun 2012, In: Journal of Molecular and Cellular Cardiology. 52, 6, p. 1299-1307 9 p.Research output: Contribution to journal › Article › peer-review
117 Citations (Scopus) -
2011
Novel Role for p90 Ribosomal S6 Kinase in the Regulation of Cardiac Myofilament Phosphorylation
Cuello, F., Bardswell, S. C., Haworth, R. S., Ehler, E., Sadayappan, S., Kentish, J. C. & Avkiran, M., 18 Feb 2011, In: Journal of Biological Chemistry. 286, 7, p. 5300 - 5310 11 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
2010
Distinct Sarcomeric Substrates Are Responsible for Protein Kinase D-mediated Regulation of Cardiac Myofilament Ca2+ Sensitivity and Cross-bridge Cycling
Bardswell, S. C., Cuello, F., Rowland, A. J., Sadayappan, S., Robbins, J., Gautel, M., Walker, J. W., Kentish, J. C. & Avkiran, M., 19 Feb 2010, In: Journal of Biological Chemistry. 285, 8, p. 5674 - 5682 9 p.Research output: Contribution to journal › Article › peer-review
94 Citations (Scopus) -
Enhanced length-dependent Ca2+ activation in fish cardiomyocytes permits a large operating range of sarcomere lengths
Patrick, S. M., Hoskins, A. C., Kentish, J. C., White, E., Shiels, H. A. & Cazorla, O., May 2010, In: Journal of Molecular and Cellular Cardiology. 48, 5, p. 917 - 924 8 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Esmolol cardioplegia: the cellular mechanism of diastolic arrest
Fallouh, H. B., Bardswell, S. C., McLatchie, L. M., Shattock, M. J., Chambers, D. & Kentish, J. C., Aug 2010, In: Cardiovascular Research. 87, 3, p. 552 - 560 9 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy
Hoskins, A. C., Jacques, A., Bardswell, S. C., McKenna, W. J., Tsang, V., dos Remedios, C. G., Ehler, E., Adams, K., Jalilzadeh, S., Avkiran, M., Watkins, H., Redwood, C., Marston, S. B. & Kentish, J. C., Nov 2010, In: Journal of Molecular and Cellular Cardiology. 49, 5, p. 737 - 745 9 p.Research output: Contribution to journal › Article › peer-review
63 Citations (Scopus) -
Passive Stiffness of Myocardium From Congenital Heart Disease and Implications for Diastole
Chaturvedi, R. R., Herron, T., Simmons, R., Shore, D., Kumar, P., Sethia, B., Chua, F., Vassiliadis, E. & Kentish, J. C., Mar 2010, In: Circulation (Baltimore). 121, 8, p. 979 - 988 10 p.Research output: Contribution to journal › Article › peer-review
150 Citations (Scopus) -
2009
Functional Analysis of a Unique Troponin C Mutation, GLY159ASP, that Causes Familial Dilated Cardiomyopathy, Studied in Explanted Heart Muscle
Dyer, E. C., Jacques, A. M., Hoskins, A. C., Ward, D. G., Gallon, C. E., Messer, A. E., Kaski, J. P., Burch, M., Kentish, J. C. & Marston, S. B., Sept 2009, In: Circulation-Heart Failure. 2, 5, p. 456-464 9 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
PP2A activity in sepsis and teh importance of teh experimental model
Marshall, M. & Kentish, J., 2009, In: Cardiovascular Research.Research output: Contribution to journal › Article › peer-review
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Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia
Marshall, M., Anilkumar, N., Layland, J., Walker, S. J., Kentish, J. C., Shah, A. M. & Cave, A. C., Apr 2009, In: Cardiovascular Research. 82, 1, p. 67 - 76 10 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
2007
Protein kinase D selectively targets cardiac troponin I and regulates myofilament Ca2+ sensitivity in ventricular myocytes
Cuello, F., Bardswell, S., Haworth, R., Yin, X., Lutz, S., Wieland, T., Mayr, M., Kentish, J. & Avkiran, M., Mar 2007, In: Circulation Research. 100, 6, p. 864 - 873 10 p.Research output: Contribution to journal › Article › peer-review
90 Citations (Scopus) -
2006
Activation of myocardial contraction by the N-terminal domains of myosin binding protein-C
Herron, T. J., Rostkova, E., Kunst, G., Chaturvedi, R., Gautel, M. & Kentish, J. C., May 2006, In: Circulation Research. 98, 10, p. 1290 - 1298 9 p.Research output: Contribution to journal › Article › peer-review
81 Citations (Scopus) -
Oxidant-induced activation of type I protein kinase a is mediated by RI subunit interprotein disulfide bond formation
Brennan, J. P., Bardswell, S. C., Burgoyne, J., Fuller, W., Schroder, E., Wait, R., Begum, S., Kentish, J. C. & Eaton, P., 4 Aug 2006, In: Journal of Biological Chemistry. 281, 31, p. 21827 - 21836 10 p.Research output: Contribution to journal › Article › peer-review
214 Citations (Scopus) -
2005
Protection against endotoxemia-induced contractile dysfunction in mice with cardiac-specific expression of slow skeletal troponin I
Layland, J., Cave, A. C., Warren, C., Grieve, D. J., Sparks, E., Kentish, J. C., Solaro, R. J. & Shah, A. M., Jul 2005, In: THE FASEB JOURNAL : OFFICIAL PUBLICATION OF THE FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY. 19, 6, p. 1137 - 1139 3 p.Research output: Contribution to journal › Article › peer-review
73 Citations (Scopus) -
2004
Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function
Haworth, R. S., Cuello, F., Herron, T. J., Franzen, G., Kentish, J. C., Gautel, M. & Avkiran, M., 26 Nov 2004, In: Circulation Research. 95, 11, p. 1091 - 1099 9 p.Research output: Contribution to journal › Article › peer-review
135 Citations (Scopus) -
2002
Myofilament-based relaxant effect of isoprenaline revealed during work-loop contractions in rat cardiac trabeculae
Layland, J. & Kentish, J. C., 1 Oct 2002, In: The Journal of Physiology. 544, 1, p. 171 - 182 12 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
2001
Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle
Kentish, J. C., McCloskey, D. T., Layland, J., Palmer, S., Leiden, J. M., Martin, A. F. & Solaro, R. J., 25 May 2001, In: Circulation Research. 88, 10, p. 1059 - 1065 7 p.Research output: Contribution to journal › Article › peer-review
291 Citations (Scopus) -
2000
Effects of alpha(1)- or beta-adrenoceptor stimulation on work-loop and isometric contractions of isolated rat cardiac trabeculae
Layland, J. & Kentish, J. C., 2000, In: The Journal of Physiology. 524, 1, p. 205 - 219 15 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus)