Jordi Alastruey
    • SE1 7EH

      United Kingdom

    • 3798
      Citations

    Personal profile

    Biographical details

    Dr Alastruey is a Senior Lecturer of Biomedical Engineering at King's College London. He graduated with an MSc in Civil Engineering (Structures, First Class) from the Polytechnic University of Catalonia and obtained a PhD in Bioengineering from Imperial College London. His thesis focused on the development, validation and application of a nonlinear one-dimensional model of pulse wave propagation the arterial network. He then conducted postdoctoral research on computational flow modelling in the cardiovascular system at the Departments of Aeronautics and Bioengineering, Imperial College. In 2009 he was awarded a British Heart Foundation research fellowship; he started his fellowship research at Imperial before moving to King's College in 2011. He was promoted to Lecturer in 2013 and to Senior Lecturer in 2017.

    Research interests

    Dr Alastruey's lab (www.haemod.uk) specialises in cardiovascular haemodynamics. They investigate methods to assess cardiovascular (CV) function based on the analysis of pulse wave signals, such as blood pressure, blood flow and PPG waves. These signals can be measured in vivo using a variety of devices (including wearable sensors) and are influenced by the heart, the vasculature, and the respiratory and autonomic nervous systems, making them a rich source of information. 

    The lab develops novel models for simulating pulse wave signals under a variety of physiological and patho-physiological conditions, methods for calibrating these models and understanding physical mechanisms underlying their results, and signal processing techniques to support clinical decision making.

    An important computational tool for the group's research activities is the in-house code Nektar1D, which Dr Alastruey started developing during his PhD. Nektar1D simulates blood pressure, blood flow and luminal area waves in a given network of compliant vessels using the nonlinear, one-dimensional (1D) formulation of blood flow in compliant vessels. Nektar1D has allowed us to show that fast and accurate calculation of pulse wave signals in large arteries is feasible on a standard PC.

    Additional information on Dr Alastruey's research can be found here. Complete lists of his peer-reviewed journal papers with citations can be found in his ScopusGoogle Scholar and Research Gate profiles.

    Research interests (short)

    Dr Alastruey's lab (www.haemod.uk) specialises in cardiovascular haemodynamics. They develop novel models for simulating pulse wave signals - such as blood pressure, blood flow and PPG waves - under a variety of physiological and patho-physiological conditions, methods for calibrating these models and understanding physical mechanisms underlying their results, as well as signal processing techniques to assess the functions of the cardiovascular, respiratory and autonomic nervous systems from pulse wave signals acquired by a variety of devices (including wearable sensors).

    Additional information on Dr Alastruey's research can be found here. Complete lists of his peer-reviewed journal papers with citations can be found in his ScopusGoogle Scholar and Research Gate profiles.

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    • SDG 3 - Good Health and Well-being

    Education/Academic qualification

    Doctor of Philosophy, Numerical Modelling of Pulse Wave Propagation in the Cardiovascular System: Development, Validation and Applications, Imperial College London

    Award Date: 1 Jan 2006

    Master of Engineering, Numerical Modelling of Pulse Wave Propagation in the Vascular System, Universitat Politècnica de Catalunya

    Award Date: 1 Jan 2002

    External positions

    Leader for the Working Group "Physiological and Technical Background - from Bench to Bedside", COST Action Network for Research in Vascular Ageing

    Nov 2019 → …

    Keywords

    • TA Engineering (General). Civil engineering (General)
    • Biomedical Engineering
    • Cardiovascular modelling
    • Arterial haemodynamics
    • Pulse wave analysis
    • Blood pressure
    • Hypertension
    • Vascular ageing

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