Personal profile
Research interests
The focus of the Bateman Laboratory is to understand basic processes in neural development and function by identifying key pathways and genes involved and to use this information to provide novel insight into neuropathological disease.
Our two main areas of interest are:
Education/Academic qualification
Doctor of Philosophy, UCL University College London
Award Date: 1 Jan 1999
Bachelor of Science, UCL University College London
Award Date: 1 Jan 1995
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 16 Peace, Justice and Strong Institutions
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Collaborations and top research areas from the last five years
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mTOR pathway diseases: challenges and opportunities from bench to bedside and the mTOR node
Mantoan Ritter, L., Annear, N. M. P., Baple, E. L., Ben-Chaabane, L. Y., Bodi, I., Brosson, L., Cadwgan, J. E., Coslett, B., Crosby, A. H., Davies, D. M., Daykin, N., Dedeurwaerdere, S., Dühring Fenger, C., Dunlop, E. A., Elmslie, F. V., Girodengo, M., Hambleton, S., Jansen, A. C., Johnson, S. R. & Kearley, K. C. & 23 others, , Dec 2025, In: Orphanet Journal of Rare Diseases. 20, 1, 256.Research output: Contribution to journal › Review article › peer-review
Open Access5 Citations (Scopus) -
A Drosophila model of mitochondrial disease phenotypic heterogeneity
Granat, L., Knorr, D., Ranson, D., Prosad Chakrabarty, R., Chandel, N. & Bateman, J., Feb 2024, In: Biology Open. 13, 2, bio060278.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Regulation by the RNA-binding protein Unkempt at its effector interface
Shah, K., He, S., Turner, D. J., Corbo, J., Rebbani, K., Dominguez, D., Bateman, J. M., Cheloufi, S., Igreja, C., Valkov, E. & Murn, J., Dec 2024, In: Nature Communications. 15, 1, 3159.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis
Baskaran, P., Mihaylov, S. R., Vinsland, E., Shah, K., Granat, L., Ultanir, S. K., Tee, A. R., Murn, J. & Bateman, J. M., Jan 2023, In: Journal of Biological Chemistry. 299, 1, 102788.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency
Granat, L., Ranson, D., Knorr, D., Hamer, E., Chakrabarty, R. P., Mattedi, F., Fort-Aznar, L., Hirth, F., Sweeney, S., Vagnoni, A., Chandel, N. S. & Bateman, J., 3 Jul 2023, In: PLoS genetics. 19, 7, e1010793.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus)
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Parallelised ultra high-density electrophysiological assays to power epilepsy precision medicine
Bateman, J. (Primary Investigator)
1/12/2024 → 30/11/2026
Project: Research
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mTOR Pathway Diseases node
Bateman, J. (Primary Investigator) & Pal, D. (Co-Investigator)
3/07/2023 → 2/07/2028
Project: Research
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Identification of novel mTOR targets in the TSC brain
Bateman, J. (Primary Investigator)
1/12/2021 → 30/11/2023
Project: Research
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Investigating polyamines as a treatment target for mitochondrial disease
Bateman, J. (Primary Investigator) & Fernandes, C. (Co-Investigator)
1/06/2021 → 28/02/2026
Project: Research
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Alzheimer’s Research UK King’s College London Network Centre Grant
Bateman, J. (Primary Investigator), Aarsland, D. (Co-Investigator), Cash, D. (Co-Investigator), Fanto, M. (Co-Investigator), Giese, P. (Co-Investigator), Hanger, D. (Co-Investigator), Hirth, F. (Co-Investigator), Malcangio, M. (Co-Investigator), Miller, C. (Co-Investigator), Mitchell, J. (Co-Investigator), Mondal, M. (Co-Investigator), Noble, W. (Co-Investigator), Parsons, R. (Co-Investigator), Ruepp, M.-D. (Co-Investigator), Serrano Navacerrada, M. E. (Co-Investigator), So, P.-W. (Co-Investigator), Sreedharan, J. (Co-Investigator), Troakes, C. (Co-Investigator), Vagnoni, A. (Co-Investigator), Vance, C. (Co-Investigator), Vernon, A. (Co-Investigator) & academic, A. (Co-Investigator)
1/09/2020 → 30/09/2022
Project: Research
Activities
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the 'Tuberous Sclerosis Complex: From Genes to New Therapeutics’ international TSC Research Symposium in Annapolis, Maryland
Bateman, J. (Keynote/plenary speaker)
2007 → …Activity: Participating in or organising an event › Participation in conference
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Secretary of the London Fly Group
Bateman, J. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
Prizes
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Won a Cancer Research UK postdoctoral fellowship
Bateman, J. (Recipient), 2002
Prize: Fellowship awarded competitively
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Won a Royal Society Research grant
Bateman, J. (Recipient), 2005
Prize: Fellowship awarded competitively