Search results

• Active

  HERD: Multimodality Early Detection of Head and Neck Cancer Recurrence

  Ng, T. (Primary Investigator), Barber, P. (Co-Investigator), Burchell, J. (Co-Investigator), Curtis, M. (Co-Investigator), Kordasti, S. (Co-Investigator), Mathew, C. (Co-Investigator), Neves, J. (Co-Investigator), Sawyer, E. (Co-Investigator), Sinkus, R. (Co-Investigator) & Thavaraj, S. (Co-Investigator)

  CRUK Cancer Research UK

  1/03/2021 → 28/02/2026

  Project: Research

• Not started

  O-linked Bca

  Burchell, J. (Primary Investigator)

  Project: Research

• Finished

  CAR T-cell mediated co-targeting of MUC1 and HER2 to achieve precision immunotherapy of breast cancer

  Maher, J. (Primary Investigator) & Burchell, J. (Co-Investigator)

  Breast Cancer Now

  2/01/2019 → 10/08/2022

  Project: Research

• Development of a specific cancer immunotherapeutic that targets an innate immune checkpoint

  Burchell, J. (Primary Investigator), Karagiannis, S. (Co-Investigator) & Beavil, A. (Co-Investigator)

  MRC Medical Research Council

  1/02/2018 → 31/03/2019

  Project: Research

  • Malignant Neoplasm 100%

• The MUC1-ST/Siglec-9 innate check point axis in cancer: prevalence, prognostic significance and potential therapeutics

  Burchell, J. (Primary Investigator) & academic, A. (Co-Investigator)

  MRC Medical Research Council

  1/08/2017 → 31/10/2020

  Project: Research

• Harnessing parallel (p)CAR technology to target T-cells against tumour-associated MUC1

  Maher, J. (Primary Investigator), Burchell, J. (Co-Investigator) & Owen, D. (Co-Investigator)

  1/01/2017 → 31/12/2019

  Project: Research

• Modulation of the immune microenvironment of breast cancers by aberrantlyglycosylated MUC1

  Burchell, J. (Primary Investigator)

  1/01/2017 → 31/12/2019

  Project: Research

• The role of aberrant O-linked glycosylation in breast cancer metastasis

  Burchell, J. (Primary Investigator), Garcia-Manyes, S. (Co-Investigator), Ivetic, A. (Co-Investigator) & academic, A. (Co-Investigator)

  1/02/2016 → 31/01/2019

  Project: Research

• Development of antibody-based therapy for Borrmann's type 4 gastric cancer targeting glycoproteins carrying a cancer specific O-glycan (GlycoGastric Ab)

  Burchell, J. (Primary Investigator)

  1/01/2016 → 31/12/2018

  Project: Research

• Metallo-drugs and Bioinspired Nano-filomicelles for Targeting Breast Cancer Stem Cells

  Suntharalingam, R. (Primary Investigator) & Burchell, J. (Co-Investigator)

  1/10/2015 → 30/09/2018

  Project: Research

• Molecular mechanisms of breast cancer related lymphoedema

  Burchell, J. (Primary Investigator) & Purushotham, A. (Co-Investigator)

  1/08/2015 → 31/07/2016

  Project: Research

• The role of aberrant O-linked glycosylation in breast cancer

  Burchell, J. (Primary Investigator), Graham, R. (Co-Investigator), Purushotham, A. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/05/2015 → 30/04/2020

  Project: Research

• Control of expression of cavelolin-1 by KDM5B in breast cancer

  Burchell, J. (Primary Investigator), Grigoriadis, A. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/01/2015 → 31/12/2015

  Project: Research

• Targeting DNGR-1 with antibody/tumour-associated peptide fusion proteins for immunotherapy of cancer

  Burchell, J. (Primary Investigator), Diebold, S. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/10/2014 → 30/09/2017

  Project: Research

• Immonocytokine targeted CAR T-cell immunotherapy of breast cancer

  Maher, J. (Primary Investigator), Burchell, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2014 → 30/06/2015

  Project: Research

• Combining histone demethylase inhibitors with HER-2 antibodies for therapy of HER-2+ve breast cancer

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2014 → 31/03/2017

  Project: Research

• Drug repurposing for combination therapy of HER2+ breast cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/06/2014 → 31/05/2015

  Project: Research

• Combining histone demethylase inhibitors with HER-2 antibodies for improved therapy of HER-2 + ve breast cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/02/2014 → 31/01/2015

  Project: Research

• GLYCO-IMMUNE: Defining important glycan interaction for enhancement of the immune response

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/01/2014 → 31/12/2016

  Project: Research

• Evaluation of targeting DNGR-1 (a novel C-type lectin) with antibody/tumour-associated epitopes as a therapy for breast cancer patients

  Burchell, J. (Primary Investigator), Diebold, S. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2013 → 30/06/2016

  Project: Research

• The role of O-linked glycosylation in breast cancer bone marrow metastasis

  Burchell, J. (Primary Investigator) & Dontu, G. (Co-Investigator)

  KHP King's Health Partners

  1/03/2013 → 31/08/2014

  Project: Research

• Chemical validation of Sialyl Lewis Z as a therapeutic target in metastatic breast cancer

  Wagner, G. (Primary Investigator), Burchell, J. (Co-Investigator) & Ivetic, A. (Co-Investigator)

  1/02/2013 → 31/01/2015

  Project: Research

• Knocking out of KDM5B in breast cnacer cell lines using zinc finger nuclease technology

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  2/01/2013 → 1/07/2013

  Project: Research

• An epigenetic approach to the characterisation of stem cells in ER+ve breast cancers aiming to identify therapeutic targets

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Primary Investigator)

  1/12/2012 → 30/11/2015

  Project: Research

• Role of KDM5B in breast cancer: unique among the KDMB5 family?

  Burchell, J. (Primary Investigator)

  1/11/2012 → 31/10/2015

  Project: Research

• Carbohydrate biomarkers for epithelial cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  NIH National Institutes of Health

  4/09/2012 → 30/06/2017

  Project: Research

• Carbohydrate Biomarkers for Epithelial Cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2012 → 30/06/2017

  Project: Research

• CD44 carrying Sialyl Lewis X as a breast stem cell marker and its involvement in metastasis

  Burchell, J. (Primary Investigator), Dontu, G. (Co-Investigator) & Maher, J. (Co-Investigator)

  1/06/2012 → 31/05/2015

  Project: Research

• Growth hormone signalling in mammary stem cells - implications for biomarker development and prevention

  Dontu, G. (Primary Investigator), Burchell, J. (Co-Investigator) & Lombardi, G. (Co-Investigator)

  1/05/2012 → 30/04/2015

  Project: Research

• Dissecting transcriptional networks underlying breast cancer: importance of TFAP2C, Myc and KDM5B centred regulatory systems

  Burchell, J. (Primary Investigator)

  1/04/2012 → 31/03/2019

  Project: Research

• Defining the role of aberrant O-linked glycosylation in breast cancer

  Burchell, J. (Primary Investigator)

  MRC Medical Research Council

  1/04/2012 → 31/01/2016

  Project: Research

• Changes in H3K4me3, H3K4me2 and H3K27me3 marks in differentiation in the human mammary gland.

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/01/2012 → 31/12/2014

  Project: Research

• Characterisation of the immunosuppressive effects of the breast cancer-associated mucin, MUC1

  Burchell, J. (Primary Investigator) & Maher, J. (Primary Investigator)

  Breast Cancer Campaign

  1/01/2012 → 31/07/2015

  Project: Research

• Involvement of the JARID1B H3K4 demythlase in Eralpha signalling

  Burchell, J. (Primary Investigator), Gee, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/05/2011 → 30/04/2014

  Project: Research

• Mapping bivalent histone marks (H3K4me3/H3K27me3) in normal and malignant human mammary gland phenotypes

  Burford, B. (Primary Investigator) & Burchell, J. (Co-Investigator)

  1/04/2011 → 31/03/2014

  Project: Research

• To determine if Sialyl Lex is carried on CD44 in a breast cancer stem cell enriched population

  Burchell, J. (Primary Investigator) & Dontu, G. (Primary Investigator)

  Breast Cancer Campaign

  1/01/2011 → 30/09/2011

  Project: Research

• Involvement of the JARID1B H3K4 demethylase in ERalpha signalling

  Burchell, J. (Primary Investigator), Carroll, J. (Co-Investigator), Gee, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  Worldwide Cancer Research

  1/10/2010 → 31/03/2014

  Project: Research

• The influence of post translational modification, o-linked glycosylation, on tumour progression.

  Burchell, J. (Primary Investigator)

  1/10/2010 → 30/09/2013

  Project: Research

• Influence of aberrant O-linked glycosylation on primary breast cancer development and sites of metastasis

  Burchell, J. (Primary Investigator)

  1/09/2010 → 31/08/2013

  Project: Research

• Evaluation of targeting DNGR-1, (a novel c-type lectin) with antibody/MUC1 peptide conjugates, as vaccine for carcinomas

  Burchell, J. (Primary Investigator) & Reis E Sousa, C. (Co-Investigator)

  CRUK Cancer Research UK

  1/08/2010 → 31/08/2012

  Project: Research

• Harnessing the tumour-derived cytokine, CSF-1 to support adoptive immunotherapy of ovarian cancer using MUC1-targeted T-cells

  Maher, J. (Primary Investigator), Burchell, J. (Co-Investigator), Hagemann, T. (Co-Investigator), Mullen, G. (Co-Investigator), Wilkie, S. (Co-Investigator) & academic, A. (Co-Investigator)

  1/06/2010 → 31/05/2013

  Project: Research

• Involvement of the PLU-1/JARID1b H3K4 demethylase in ER signalling

  Burchell, J. (Primary Investigator), Carroll, B. (Co-Investigator), Taylor-Papadimitriou, J. (Co-Investigator) & Thomas, S. (Co-Investigator)

  1/04/2010 → 31/12/2010

  Project: Research

• Detection of auto-antibodies to aberrantly glycosylated glycoproteins as a screening assay for breast cancer

  Burchell, J. (Primary Investigator), Blixt, O. (Co-Investigator), Clausen, H. (Co-Investigator), Fentiman, I. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/03/2010 → 28/02/2013

  Project: Research

• Immune reactivity in newly diagnosed breast cancer

  Arif, S. (Primary Investigator), Harries, M. (Primary Investigator), Maher, J. (Primary Investigator) & Burchell, J. (Co-Investigator)

  Guy's & St Thomas' Charity

  1/02/2010 → 31/07/2011

  Project: Research

• Mutually assured destruction of breast cancer using genetically targeted T-cells that produce reciprocally supportive cytokines

  Maher, J. (Primary Investigator), Antoniou, M. (Co-Investigator), Burchell, J. (Co-Investigator), Harries, M. (Co-Investigator), Lombardi, G. (Co-Investigator), Mullen, G. (Co-Investigator), Purushotham, A. (Co-Investigator), Spicer, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  6/01/2010 → 5/01/2013

  Project: Research

• Influence of aberrant o-glysolation on primary breast cancer development and sites of metastases

  Burchell, J. (Primary Investigator)

  1/10/2009 → 30/09/2012

  Project: Research

• Control of expression of glycosyltransferases involved in o-linked glycosylation in breast cancer

  Burchell, J. (Primary Investigator), Gillett, C. (Co-Investigator) & Parker, P. (Co-Investigator)

  1/10/2009 → 30/09/2013

  Project: Research

• Control of expression of glycosyltransferases involved in O-linked glysoylation in breast cancer

  Burchell, J. (Primary Investigator) & Ridley, A. (Co-Investigator)

  1/10/2009 → 30/09/2012

  Project: Research

• Control of expression of glycosyltransferases involved in O-linked glycosylation in breast cancer

  Burchell, J. (Primary Investigator) & Ridley, A. (Co-Investigator)

  Breast Cancer Campaign

  14/09/2009 → 30/09/2012

  Project: Research

• Immunotherapy of ovarian cancer using t-cells engrafted with chimeric antigen and cytokine receptors

  Burchell, J. (Primary Investigator), Maher, J. (Primary Investigator), Farzaneh, F. (Co-Investigator) & Mullen, G. (Co-Investigator)

  1/09/2009 → 31/08/2012

  Project: Research