Search results

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  The role of aberrant O-linked glycosylation in breast cancer

  Burchell, J. (Primary Investigator), Graham, R. (Co-Investigator), Purushotham, A. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/05/2015 → 30/04/2020

  Project: Research

• Control of expression of cavelolin-1 by KDM5B in breast cancer

  Burchell, J. (Primary Investigator), Grigoriadis, A. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/01/2015 → 31/12/2015

  Project: Research

• Targeting DNGR-1 with antibody/tumour-associated peptide fusion proteins for immunotherapy of cancer

  Burchell, J. (Primary Investigator), Diebold, S. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/10/2014 → 30/09/2017

  Project: Research

• Immonocytokine targeted CAR T-cell immunotherapy of breast cancer

  Maher, J. (Primary Investigator), Burchell, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2014 → 30/06/2015

  Project: Research

• Combining histone demethylase inhibitors with HER-2 antibodies for therapy of HER-2+ve breast cancer

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2014 → 31/03/2017

  Project: Research

• Drug repurposing for combination therapy of HER2+ breast cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/06/2014 → 31/05/2015

  Project: Research

• Combining histone demethylase inhibitors with HER-2 antibodies for improved therapy of HER-2 + ve breast cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/02/2014 → 31/01/2015

  Project: Research

• GLYCO-IMMUNE: Defining important glycan interaction for enhancement of the immune response

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/01/2014 → 31/12/2016

  Project: Research

• Evaluation of targeting DNGR-1 (a novel C-type lectin) with antibody/tumour-associated epitopes as a therapy for breast cancer patients

  Burchell, J. (Primary Investigator), Diebold, S. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2013 → 30/06/2016

  Project: Research

• Knocking out of KDM5B in breast cnacer cell lines using zinc finger nuclease technology

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  2/01/2013 → 1/07/2013

  Project: Research

• An epigenetic approach to the characterisation of stem cells in ER+ve breast cancers aiming to identify therapeutic targets

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Primary Investigator)

  1/12/2012 → 30/11/2015

  Project: Research

• Carbohydrate biomarkers for epithelial cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  NIH National Institutes of Health

  4/09/2012 → 30/06/2017

  Project: Research

• Carbohydrate Biomarkers for Epithelial Cancers

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/07/2012 → 30/06/2017

  Project: Research

• Characterisation of stem cells in ER+ cancer

  Taylor-Papadimitriou, J. (Primary Investigator)

  1/05/2012 → 31/01/2013

  Project: Research

• Knock down of JARID1B: effects on growth of breast cancer stem cells

  Taylor-Papadimitriou, J. (Primary Investigator)

  1/04/2012 → 30/09/2012

  Project: Research

• Changes in H3K4me3, H3K4me2 and H3K27me3 marks in differentiation in the human mammary gland.

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/01/2012 → 31/12/2014

  Project: Research

• Involvement of the JARID1B H3K4 demythlase in Eralpha signalling

  Burchell, J. (Primary Investigator), Gee, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/05/2011 → 30/04/2014

  Project: Research

• Involvement of the JARID1B H3K4 demethylase in ERalpha signalling

  Burchell, J. (Primary Investigator), Carroll, J. (Co-Investigator), Gee, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  Worldwide Cancer Research

  1/10/2010 → 31/03/2014

  Project: Research

• Involvement of the PLU-1/JARID1b H3K4 demethylase in ER signalling

  Burchell, J. (Primary Investigator), Carroll, B. (Co-Investigator), Taylor-Papadimitriou, J. (Co-Investigator) & Thomas, S. (Co-Investigator)

  1/04/2010 → 31/12/2010

  Project: Research

• Detection of auto-antibodies to aberrantly glycosylated glycoproteins as a screening assay for breast cancer

  Burchell, J. (Primary Investigator), Blixt, O. (Co-Investigator), Clausen, H. (Co-Investigator), Fentiman, I. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/03/2010 → 28/02/2013

  Project: Research

• Mutually assured destruction of breast cancer using genetically targeted T-cells that produce reciprocally supportive cytokines

  Maher, J. (Primary Investigator), Antoniou, M. (Co-Investigator), Burchell, J. (Co-Investigator), Harries, M. (Co-Investigator), Lombardi, G. (Co-Investigator), Mullen, G. (Co-Investigator), Purushotham, A. (Co-Investigator), Spicer, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  6/01/2010 → 5/01/2013

  Project: Research

• Control of cell fate by the H3K4 histone demethlases PLU-1/JAIRD1B in breast cancer

  Taylor-Papadimitriou, J. (Primary Investigator) & Burchell, J. (Co-Investigator)

  Breast Cancer Campaign

  1/05/2009 → 31/07/2010

  Project: Research

• Control of gene expression and cell fate by the H3K4 histone demethylase PLU-1/JARID1B in breast cancer

  Taylor-Papadimitriou, J. (Primary Investigator), Barrett, A. (Co-Investigator) & Burchell, J. (Co-Investigator)

  1/01/2009 → 31/12/2011

  Project: Research

• Investigations intothe function of the H3K4 demethylase, PLU-1/JARID1B, in breast cancer

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  1/10/2008 → 30/09/2012

  Project: Research

• PLU-1/JARID1B and signalling from the ER nuclear receptor

  Catchpole, S. (Primary Investigator) & Taylor-Papadimitriou, J. (Primary Investigator)

  Breast Cancer Campaign

  1/07/2008 → 30/06/2009

  Project: Research

• Discovery of novel cancer serum biomarkers based on aberrant post translational modifications of O-glycoproteins (O-PTM biomarkers) and their application to early detection of cancer

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Primary Investigator)

  EC European Commission

  1/01/2008 → 31/03/2011

  Project: Research

• Investigations into the function of the H3K4 demethylase, PLU-1JARID1B, in breast cancer

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Primary Investigator)

  Breast Cancer Campaign

  1/12/2007 → 31/03/2011

  Project: Research

• Interactions of tumour-associated immungenic glycoforms of MUC1 with lectins of the immune system.

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  Breast Cancer Campaign

  1/10/2007 → 30/09/2010

  Project: Research

• Autoantibodies against glycopeptide epitodes as werum biomarkers of cancer

  Burchell, J. (Primary Investigator), Taylor-Papadimitriou, J. (Primary Investigator), Blixt, O. (Co-Investigator), Clausen, H. (Co-Investigator), Fentiman, I. (Co-Investigator) & Hollingsworth, M. (Co-Investigator)

  NIH National Institutes of Health

  21/09/2007 → 31/03/2013

  Project: Research

• Epigenetic regulation of expression of BRCA1 and checkpoint genes by PLU-1/JARID1B

  Taylor-Papadimitriou, J. (Primary Investigator)

  Breast Cancer Campaign

  16/07/2007 → 15/02/2008

  Project: Research

• Dual targeting of MUC1 and ErbB2 in the adoptive immunotherapy of breast cancer

  Maher, J. (Primary Investigator), Burchell, J. (Co-Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  Breast Cancer Campaign

  1/06/2007 → 5/06/2010

  Project: Research

• Identification of lectin-like receptors that bind specific tumour-associated glycoforms of muc1 and the functional consequences

  Burchell, J. (Primary Investigator) & Taylor-Papadimitriou, J. (Co-Investigator)

  CRUK Cancer Research UK

  1/09/2006 → 30/09/2010

  Project: Research

• King's Experimental Cancer Centre

  Parker, P. (Primary Investigator), Purushotham, A. (Primary Investigator), Blower, P. (Co-Investigator), Burchell, J. (Co-Investigator), Diebold, S. (Co-Investigator), Ellis, P. (Co-Investigator), Farzaneh, F. (Co-Investigator), Gillett, C. (Co-Investigator), Grimwade, D. (Co-Investigator), Harries, M. (Co-Investigator), Hayday, A. (Co-Investigator), Lewis, C. (Co-Investigator), Marsden, P. (Co-Investigator), Mufti, G. (Co-Investigator), Møller, H. (Co-Investigator), Nestle, F. (Co-Investigator), Ng, T. (Co-Investigator), O'Doherty, M. (Co-Investigator), Sawyer, E. (Co-Investigator), Schey, S. (Co-Investigator), Solomon, E. (Co-Investigator), Spencer, J. (Co-Investigator), Taylor-Papadimitriou, J. (Co-Investigator), Tutt, A. (Co-Investigator) & Whittaker, S. (Co-Investigator)

  CRUK Cancer Research UK

  1/08/2006 → 31/03/2012

  Project: Research

• Changes in glycosylationof tumour antigen

  Taylor-Papadimitriou, J. (Primary Investigator)

  CRUK Cancer Research UK

  1/03/2005 → 16/05/2008

  Project: Research

• Expression and function of a novel gene PLU-1 with DNA/chromatin binding motifs in breast cancer

  Taylor-Papadimitriou, J. (Primary Investigator)

  Guy's & St Thomas' Charity

  18/12/1998 → 30/09/2002

  Project: Research