Research output per year
Research output per year
Personal profile
Research interests
Regulation of intracellular Ca2+ in platelets and vascular cells. Mechanisms of platelet activation. Characterisation of TRP channels, STIM proteins, Orai and IP3R.
Research interests (short)
Ca2+ signalling in platelets and related cells; platelet activation.
Biographical details
Dr. Kalwant Authi is an inventor and author of non-exclusive licence agreements regarding platelet related materials between King’s College London and two biotechnology companies (Sigma- Aldrich Israel Ltd., and Santa Cruz Biotechnology Inc. USA.)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Development of small-molecule fluorescent probes targeting neutrophils via N-formyl peptide receptors
Xu, Q., Authi, K. S., Kirpotina, L. N., Schepetkin, I. A., Quinn, M. T. & Cilibrizzi, A., 2025, (Accepted/In press) In: RSC Medicinal Chemistry.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of small-molecule fluorescent probes targeting neutrophils via N-formyl peptide receptors
Xu, Q., Authi, K. S., Kirpotina, L. N., Schepetkin, I. A., Quinn, M. T. & Cilibrizzi, A., 14 Jan 2025, In: RSC Medicinal Chemistry. 16, 3, p. 1397-1409 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
P2Y14 receptor activation of platelets induces Ca2+ mobilization and Rho-GTPase-dependent motility that requires an interaction with P2Y1 receptors
Hossain, M. M., Pan, D., Arkless, K. L., Rahman, K. M., Page, C. P., Authi, K. S. & Pitchford, S. C., 18 Feb 2025, (E-pub ahead of print) In: British Journal of Pharmacology. 182, 13, p. 2950-2967 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Professor Neville Crawford: An inspirational platelet scientist, 1927–2015
Authi, K., 17 Aug 2016, In: PLATELETS. 27, 6, p. 603-604 2 p.Research output: Contribution to journal › Editorial › peer-review
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Phosphatidylinositol-3,4,5-trisphosphate stimulates Ca2+ elevation and Akt phosphorylation to constitute a major mechanism of thromboxane A2 formation in human platelets
Kassouf, N., Ambily, A., Watson, S., Hassock, S., Authi, H. S., Srivastava, S., Watson, S. P. & Authi, K. S., Jul 2015, In: Cellular Signalling. 27, 7, p. 1488-1498 11 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus)
Projects
- 10 Finished
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Characterisation of RASA3 interaction with integrin andcytoskeletal protein in platelets
Brain, S. (Co-Investigator) & Authi, K. (Primary Investigator)
20/01/2020 → 19/09/2023
Project: Research
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The role of Inositol (1,4,5)trisphosphate receptor 2 ( IP3R2) in platelet function, thrombus formation and vascular permeability
Authi, K. (Primary Investigator), Fraser, P. (Co-Investigator) & Mann, G. (Co-Investigator)
1/02/2017 → 31/01/2019
Project: Research
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The role of inositol (1,4,5) trisphosphate receptor 2 in platelet function, thrombus formation and vascular permeability
Authi, K. (Primary Investigator), Fraser, P. (Co-Investigator) & Mann, G. (Co-Investigator)
1/05/2016 → 1/04/2018
Project: Research
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The organisation of plasma membrane STIM1 and Orai1 in human platelets and their role in thrombus formation.
Authi, K. (Primary Investigator) & Mann, G. (Co-Investigator)
1/10/2014 → 1/09/2017
Project: Research
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Organisation of stim1 and orai1 in human platelets
Authi, K. (Primary Investigator), Aaronson, P. (Co-Investigator) & Mayr, M. (Co-Investigator)
1/09/2013 → 31/08/2015
Project: Research
Activities
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Nottingham Platelet Conference
Authi, K. (Chair)
15 Jul 2012 → 16 Jul 2012Activity: Participating in or organising an event › Participation in conference
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9th UK platelet meeting to be held at King's College London
Authi, K. (Organiser)
Sept 2007 → …Activity: Participating in or organising an event › Participation in conference
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Chaired session in 8th UK Platelet meeting, University of Reading 7-8 September 2006
Authi, K. (Chair)
Sept 2006 → …Activity: Participating in or organising an event › Participation in conference
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one session
Authi, K. (Chair)
Oct 2004 → …Activity: Participating in or organising an event › Participation in conference
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XIX European Platelet meeting, Bad Bruckenau, Germany. Invited speaker
Authi, K. (Invited speaker)
Oct 2004 → …Activity: Participating in or organising an event › Participation in conference