Research output per year
Research output per year
Personal profile
Research interests
Memory processes, including memory formation, storage, retrieval, and extinction, are fundamental for brain function and they are affected in various psychiatric illnesses such as mental retardation, Alzheimer's disease, and post-traumatic stress disorder. Currently, the biological basis of memory processes is not sufficiently well understood to develop successful treatments for memory dysfunctions. However, the advent of sophisticated molecular techniques now allows for an advanced analysis of memory processes in experimental animals, which promises to be translated for the patients.
Research interests (short)
Neural basis of learning and memory.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, ETH Zurich
Award Date: 1 Jan 1992
Master of Chemistry, Ruhr-University Bochum
Award Date: 1 Jan 1989
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Collaborations and top research areas from the last five years
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A revised view of the role of CaMKII in learning and memory
Bayer, K. U. & Giese, P., 18 Nov 2024, In: Nature neuroscience.Research output: Contribution to journal › Review article › peer-review
2 Citations (Scopus) -
Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia
Peng, X., Wellard, N., Ghosh, A. G., Troakes, C. & Giese, P., Jan 2024, In: Brain Research Bulletin. 206, 110849.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
The intellectual disability risk gene Kdm5b regulates long term memory consolidation in the hippocampus
Perez Sisques, L., Bhatt, S., Matuleviciute, R., Gileadi, T., Kramar, E., Graham, A., Garcia, F. G., Keiser, A., Matheos, D. P., Cain, J., Pittman, A. M., Andreae, L., Fernandes, C., Wood, M. A., Giese, P. & Basson, A., 8 May 2024, (E-pub ahead of print) In: The Journal of neuroscience : the official journal of the Society for Neuroscience.Research output: Contribution to journal › Article › peer-review
Open Access -
Using deep learning to quantify neuronal activation from single-cell and spatial transcriptomic data
Bahl, E., Chatterjee, S., Mukherjee, U., Elsadany, M., Vanrobaeys, Y., Lin, L.-C., McDonough, M., Resch, J., Giese, K. P., Abel, T. & Michaelson, J. J., 26 Jan 2024, In: Nature Communications. 15, 1, 779.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer's disease
Rupawala, H., Shah, K., Davies, C., Rose, J., Colom-Cadena, M., Peng, X., Granat, L., Aljuhani, M., Mizuno, K., Troakes, C., Gomez Perez-Nievas, B., Morgan, A., So, P.-W., Hortobagyi, T., Spires-Jones, T., Noble, W. & Giese, P., 23 Jul 2022, In: Brain Communications. 4, 4, p. fcac192 fcac192.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)155 Downloads (Pure)
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Alzheimer's Research UK London Network Centre Grant Year 4
Giese, P. (Primary Investigator)
1/01/2025 → 31/12/2025
Project: Research
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The Role of Amyloid Pathology in the Thalamus in the Early Stages of Alzheimer's Disease
Delogu, A. (Primary Investigator) & Giese, P. (Co-Investigator)
1/10/2024 → 30/09/2026
Project: Research
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Alzheimer's Research UK London Network Centre Grant
Giese, P. (Primary Investigator)
1/01/2024 → 30/06/2025
Project: Research
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MNKtreat: A novel route for preventing synapse and memory loss in Alzheimer’s disease: Inhibition of MNK
Giese, P. (Primary Investigator) & Srivastava, D. (Co-Investigator)
1/07/2022 → 30/06/2025
Project: Research
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Analysis of Amyloid-beta -induced Protein Synthesis
Giese, P. (Primary Investigator) & Mizielinska, S. (Co-Investigator)
UKDRI UK Dementia Research Institute
1/10/2023 → 30/09/2024
Project: Research