King's College London

Research portal

Dr Katherine Aitchison

  1. Trajectories of suicidal ideation during 12 weeks of escitalopram or nortriptyline antidepressant treatment among 811 patients with major depressive disorder

    Madsen, T., Buttenschøn, H. N., Uher, R., Behrendt-Møller, I., Perroud, N., Maier, W., Hauser, J., Dernovsek, M. Z., Henigsberg, N., Souery, D., Rietschel, M., McGuffin, P., Aitchison, K. J., Mors, O. & Köhler-Forsberg, O., 16 Jul 2019, In : Journal of Clinical Psychiatry. 80, 4, 18m12575.

    Research output: Contribution to journalArticle

  2. Differential gene expression analysis in blood of first episode psychosis patients

    Leirer, D. J., Iyegbe, C. O., Di Forti, M., Patel, H., Carra, E., Fraietta, S., Colizzi, M., Mondelli, V., Quattrone, D., Lally, J., Ajnakina, O., Lee, S. H., Curtis, C. J., Breen, G., Pariante, C., Aitchison, K., Dazzan, P., Murray, R. M., Dobson, R. J. B. & Newhouse, S. J., 1 Jul 2019, In : Schizophrenia Research. 209, p. 88-97 10 p.

    Research output: Contribution to journalArticle

  3. Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder

    Köhler-Forsberg, O., Larsen, E. R., Buttenschon, H. N., Rietschel, M., Hauser, J., Souery, D., Maier, W., Farmer, A., McGuffin, P., Aitchison, K. J., Uher, R. & Mors, O., 2019, In : British Journal of Psychiatry. 215, 2, p. 494-501 8 p.

    Research output: Contribution to journalArticle

  4. Accepted/In press

    Psychosocial risk factors for suicidality in children and adolescents

    the STOP Consortium, 20 Dec 2018, (Accepted/In press) In : European Child and Adolescent Psychiatry.

    Research output: Contribution to journalArticle

  5. Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

    Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O., Henigsberg, N., Hauser, J., Zobel, A., Maier, W., Dernovsek, M. Z., Souery, D., Cattaneo, A., Breen, G., Craig, I. W., Farmer, A. E., McGuffin, P., Lewis, C. M. & Aitchison, K. J., 1 Dec 2018, In : Translational psychiatry. 8, 1, 150.

    Research output: Contribution to journalArticle

  6. Interaction between the FTOgene, body mass index and depression: meta-analysis of 13701 individuals

    Rivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J-J., Korszun, A., Kutalik, Z., Lucae, S. & 18 others, Maier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., 1 Aug 2017, In : British Journal of Psychiatry. 211, 2, p. 70-76 7 p.

    Research output: Contribution to journalArticle

  7. Combining clinical variables to optimize prediction of antidepressant treatment outcomes

    Iniesta, R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovsek, M. Z., Souery, D., Stahl, D., Dobson, R., Aitchison, K. J., Farmer, A., Lewis, C. M., McGuffin, P. & Uher, R., Jul 2016, In : Journal of psychiatric research. 78, p. 94-102 9 p.

    Research output: Contribution to journalArticle

  8. Phenotypic Association Analyses with Copy Number Variation in Recurrent Depressive Disorder

    Rucker, J. J. H., Tansey, K. E., Rivera, M., Pinto, D., Cohen-Woods, S., Uher, R., Aitchison, K. J., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Barnes, M. R., Preisig, M., Mors, O., Maier, W., Rice, J., Rietschel, M., Holsboer, F., Farmer, A. E. & 4 others, Craig, I. W., Scherer, S. W., McGuffin, P. & Breen, G., 15 Feb 2016, In : Biological psychiatry. 79, 4, p. 329–336

    Research output: Contribution to journalArticle

  9. Transcriptomics and the mechanisms of antidepressant efficacy

    Hodgson, K., Tansey, K. E., Powell, T., Coppola, G., Uher, R., Zvezdana Dernovšek, M., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Aitchison, K. J., Craig, I. W., Farmer, A. E., Breen, G., Mcguffin, P. & Dobson, R., 1 Jan 2016, In : European Neuropsychopharmacology. 26, 1, p. 105-112 8 p.

    Research output: Contribution to journalArticle

  10. Exploring the role of drug-metabolising enzymes in antidepressant side effects

    Hodgson, K., Tansey, K. E., Uher, R., Dernovšek, M. Z., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Craig, I. W., Aitchison, K. J., Farmer, A., Dobson, R. J. B. & McGuffin, P., Jul 2015, In : Psychopharmacology. 232, 14, p. 2609-2617 9 p.

    Research output: Contribution to journalArticle

  11. Interaction Between Functional Genetic Variation of DRD2 and Cannabis Use on Risk of Psychosis

    Colizzi, M., Iyegbe, C., Powell, J., Ursini, G., Porcelli, A., Bonvino, A., Taurisano, P., Romano, R., Masellis, R., Blasi, G., Morgan, C., Aitchison, K., Mondelli, V., Luzi, S., Kolliakou, A., David, A., Murray, R. M., Bertolino, A. & Forti, M. D., 31 Mar 2015, In : Schizophrenia Bulletin. 41, 5, p. 1171-1182 12 p.

    Research output: Contribution to journalArticle

  12. Phenotypic Association Analyses with Copy Number Variation in Recurrent Depressive Disorder.

    Rucker, J. J. H., Tansey, K. E., Rivera, M., Pinto, D., Cohen-Woods, S., Uher, R., Aitchison, K. J., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Barnes, M. R., Preisig, M., Mors, O., Maier, W., Rice, J., Rietschel, M., Holsboer, F., Farmer, A. E. & 4 others, Craig, I. W., Scherer, S. W., McGuffin, P. & Breen, G., 1 Feb 2015, In : Biological psychiatry.

    Research output: Contribution to journalArticle

  13. Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

    Ferentinos, P., Koukounari, A., Power, R., Rivera, M., Uher, R., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Ising, M., Maier, W., Mors, O., Rietschel, M., Preisig, M., Binder, E. B., Aitchison, K. J., Mendlewicz, J. & 9 others, Souery, D., Hauser, J., Henigsberg, N., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M., 2015, In : Psychological Medicine. 11 p.

    Research output: Contribution to journalArticle

  14. Association of KIBRA rs17070145 polymorphism with episodic memory in the early stages of a human neurodevelopmental disorder

    Vyas, N. S., Ahn, K., Stahl, D. R., Caviston, P., Simic, M., Netherwood, S., Puri, B. K., Lee, Y. & Aitchison, K. J., 15 Dec 2014, In : Psychiatry Research. Neuroimaging. 220, 1-2, p. 37-43 7 p.

    Research output: Contribution to journalArticle

  15. Effects of Antidepressant Drug Exposure on Gene Expression in the Developing Cerebral Cortex

    Tsapakis, E. M., Fernandes, C., Moran-Gates, T., Basu, A., Sugden, K., Aitchison, K. J. & Tarazi, F. I., May 2014, In : Synapse. 68, 5, p. 209-220 12 p., N/A.

    Research output: Contribution to journalArticle

  16. Genetic predictors of antidepressant side effects: A grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study

    Hodgson, K., Uher, R., Crawford, A. A., Lewis, G., O'Donovan, M. C., Keers, R., Dernovsek, M. Z., Mors, O., Hauser, J., Souery, D., Maier, W., Henigsberg, N., Rietschel, M., Placentino, A., Aitchison, K., Farmer, A., Davis, O. & McGuffin, P., Feb 2014, In : Journal of Psychopharmacology. 28, 2, p. 142-150 9 p., N/A.

    Research output: Contribution to journalArticle

  17. Copy number variants and therapeutic response to antidepressant medication in major depressive disorder.

    Tansey, K. E., Rucker, J. J. H., Kavanagh, D. H., Guipponi, M., Perroud, N., Bondolfi, G., Domenici, E., Evans, D. M., Hauser, J., Henigsberg, N., Jerman, B., Maier, W., Mors, O., O'Donovan, M., Peters, T. J., Placentino, A., Rietschel, M., Souery, D., Aitchison, K. J., Craig, I. & 7 others, Farmer, A., Wendland, J. R., Malafosse, A., Lewis, G., Kapur, S., McGuffin, P. & Uher, R., 1 Jan 2014, In : PHARMACOGENOMICS JOURNAL. 14, 4, p. 395-399 5 p.

    Research output: Contribution to journalArticle

  18. Investigation of blood mRNA biomarkers for suicidality in an independent sample

    Mullins, N., Hodgson, K., Tansey, K. E., Perroud, N., Maier, W., Mors, O., Rietschel, M., Hauser, J., Henigsberg, N., Souery, D., Aitchison, K., Farmer, A., McGuffin, P., Breen, G., Uher, R. & Lewis, C. M., 2014, In : Translational psychiatry. 4, 4 p., e474.

    Research output: Contribution to journalArticle

  19. Duration of untreated psychosis in adolescents: ethnic differences and clinical profiles

    Dominguez, M-G., Fisher, H. L., Major, B., Chisholm, B., Rahaman, N., Joyce, J., Woolley, J., Lawrence, J., Hinton, M., Marlowe, K., Aitchison, K., Johnson, S. & Hodes, M., Nov 2013, In : Schizophrenia Research. 150, 2-3, p. 526-532 7 p., N/A.

    Research output: Contribution to journalArticle

  20. Genome-wide association analysis accounting for environmental factors through propensity-score matching: Application to stressful live events in major depressive disorder

    Power, R. A., Cohen-Woods, S., Ng, M. Y., Butler, A. W., Craddock, N., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Zobel, A., Mors, O., Placentino, A., Rietschel, M., Aitchison, K. J., Tozzi, F., Muglia, P., Breen, G., Farmer, A. E. & 3 others, McGuffin, P., Lewis, C. M. & Uher, R., Sep 2013, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 162, 6, p. 521-529 9 p., N/A.

    Research output: Contribution to journalArticle

  21. Ethnic variations in pathways into early intervention services for psychosis

    Ghali, S., Fisher, H. L., Joyce, J., Major, B., Hobbs, L., Soni, S., Chisholm, B., Rahaman, N., Papada, P., Lawrence, J., Bloy, S., Marlowe, K., Aitchison, K. J., Power, P. & Johnson, S., Apr 2013, In : British journal of psychiatry. 202, 4, p. 277-283 7 p.

    Research output: Contribution to journalArticle

  22. Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies

    Uher, R., Tansey, K. E., Rietschel, M., Henigsberg, N., Maier, W., Mors, O., Hauser, J., Placentino, A., Souery, D., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Lewis, C. M., Ising, M., Lucae, S., Binder, E. B., Kloiber, S., Holsboer, F., Müller-Myhsok, B. & 8 others, Ripke, S., Hamilton, S. P., Soundy, J., Laje, G., McMahon, F. J., Fava, M., Rush, A. J. & Perlis, R. H., 1 Feb 2013, In : The American Journal of Psychiatry. 170, 2, p. 207-217 11 p.

    Research output: Contribution to journalArticle

  23. Genome-wide association analysis of copy number variation in recurrent depressive disorder

    Rucker, J., Breen, G., Pinto, D., Pedroso, I., Lewis, C. M., Cohen-Woods, S., Uher, R., Schosser, A., Rivera, M., Aitchison, K. J., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Muglia, P., Barnes, M. R., Preisig, M., Mors, O., Gill, M. & 8 others, Maier, W., Rice, J., Rietschel, M., Holsboer, F., Farmer, A. E., Craig, I. W., Scherer, S. W. & McGuffin, P., Feb 2013, In : Molecular Psychiatry. 18, 2, p. 183-189 7 p., N/A.

    Research output: Contribution to journalArticle

  24. Dissecting the genetic heterogeneity of depression through age at onset

    Power, R., Keers, R., Ng, M. Y., Butler, A. W., Uher, R., Cohen-Woods, S., Ising, M., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Hauser, J., Henigsberg, N., Maier, W., Zobel, A., Mors, O., Placentino, A. S. & 15 others, Rietschel, M., Souery, D., Kozel, D., Preisig, M., Lucae, S., Binder, E. B., Aitchison, K. J., Tozzi, F., Muglia, P., Breen, G., Craig, I. W., Farmer, A. E., Mueller-Myhsok, B., McGuffin, P. & Lewis, C. M., Oct 2012, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 159B, 7, p. 859-868 10 p.

    Research output: Contribution to journalArticle

  25. Genetic Predictors of Response to Serotonergic and Noradrenergic Antidepressants in Major Depressive Disorder: A Genome-Wide Analysis of Individual-Level Data and a Meta-Analysis

    Tansey, K. E., Guipponi, M., Perroud, N., Bondolfi, G., Domenici, E., Evans, D., Hall, S. K., Hauser, J., Henigsberg, N., Hu, X., Jerman, B., Maier, W., Mors, O., O'Donovan, M., Peters, T. J., Placentino, A., Rietschel, M., Souery, D., Aitchison, K. J., Craig, I. & 10 others, Farmer, A., Wendland, J. R., Malafosse, A., Holmans, P., Lewis, G., Lewis, C. M., Stensbol, T. B., Kapur, S., McGuffin, P. & Uher, R., Oct 2012, In : PL o S Medicine. 9, 10, p. - 10 p., e1001326.

    Research output: Contribution to journalArticle

  26. Depressive disorder moderates the effect of the FTO gene on body mass index

    Rivera Sanchez, M., Cohen-Woods, S., Kapur, K., Breen, G., Ng, M. Y., Butler, A. W., Craddock, N., Gill, M., Korszun, A., Maier, W., Mors, O., Owen, M. J., Preisig, M., Bergmann, S., Tozzi, F., Rice, J., Rietschel, M., Rucker, J., Schosser, A., Aitchison, K. J. & 5 others, Uher, R., Craig, I. W., Lewis, C. M., Farmer, A. E. & McGuffin, P., Jun 2012, In : Molecular Psychiatry. 17, 6, p. 604-611 8 p., N/A.

    Research output: Contribution to journalArticle

  27. Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms

    Uher, R., Perlis, R. H., Henigsberg, N., Zobel, A., Rietschel, M., Mors, O., Hauser, J., Dernovsek, M. Z., Souery, D., Bajs, M., Maier, W., Aitchison, K. J., Farmer, A. & McGuffin, P., May 2012, In : Psychological Medicine. 42, 5, p. 967 - 980 14 p.

    Research output: Contribution to journalArticle

  28. CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP

    Huezo-Diaz, P., Perroud, N., Spencer, E. P., Smith, R., Sim, S., Virding, S., Uher, R., Gunasinghe, C., Gray, J., Campbell, D., Hauser, J., Maier, W., Marusic, A., Rietschel, M., Perez, J., Giovannini, C., Mors, O., Mendlewicz, J., McGuffin, P., Farmer, A. E. & 3 others, Ingelman-Sundberg, M., Craig, I. W. & Aitchison, K. J., Mar 2012, In : Journal of psychopharmacology (Oxford, England). 26, 3, p. 398-407 10 p.

    Research output: Contribution to journalArticle

  29. Can genetics inform the management of cognitive deficits in schizophrenia?

    Vyas, N. S., Shamsi, S. A., Malhotra, A. K., Aitchison, K. J. & Kumari, V., Mar 2012, In : Journal of Psychopharmacology. 26, 3, p. 334 - 348 15 p.

    Research output: Contribution to journalLiterature review

  30. Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project

    Perroud, N., Uher, R., Ng, M. Y. M., Guipponi, M., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Gennarelli, M., Rietschel, M., Souery, D., Dernovsek, M. Z., Stamp, A. S., Lathrop, M., Farmer, A., Breen, G., Aitchison, K. J., Lewis, C. M., Craig, I. W. & McGuffin, P., Feb 2012, In : PHARMACOGENOMICS JOURNAL. 12, 1, p. 68 - 77 10 p.

    Research output: Contribution to journalArticle

  31. Antidepressants and the resilience to early-life stress in inbred mouse strains

    Binder, E., Malki, K., Paya-Cano, J. L., Fernandes, C., Aitchison, K. J., Mathe, A. A., Sluyter, F. & Schalkwyk, L. C., Dec 2011, In : PHARMACOGENETICS AND GENOMICS. 21, 12, p. 779-789 11 p.

    Research output: Contribution to journalArticle

  32. Early and Delayed Onset of Response to Antidepressants in Individual Trajectories of Change During Treatment of Major Depression: A Secondary Analysis of Data From the Genome-Based Therapeutic Drugs for Depression (GENDEP) Study

    Uher, R., Mors, O., Rietschel, M., Rajewska-Rager, A., Petrovic, A., Zobel, A., Henigsberg, N., Mendlewicz, J., Aitchison, K. J., Farmer, A. & McGuffin, P., Nov 2011, In : Journal of Clinical Psychiatry. 72, 11, p. 1478 - 1484 7 p.

    Research output: Contribution to journalArticle

  33. Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: Clinical description and the role of the 5-HTTLPR

    Strohmaier, J., Wuest, S., Uher, R., Henigsberg, N., Mors, O., Hauser, J., Souery, D., Zobel, A., Dernovsek, M. Z., Streit, F., Schmael, C., Kozel, D., Placentino, A., Farmer, A., Mcguffin, P., Aitchison, K. J. & Rietschel, M., Oct 2011, In : World Journal of Biological Psychiatry. 12, 7, p. 528-538 11 p.

    Research output: Contribution to journalArticle

  34. Melancholic, atypical and anxious depression subtypes and outcome of treatment with escitalopram and nortriptyline

    Uher, R., Dernovsek, M. Z., Mors, O., Hauser, J., Souery, D., Zobel, A., Maier, W., Henigsberg, N., Kalember, P., Rietschel, M., Placentino, A., Mendlewicz, J., Aitchison, K. J., McGuffin, P. & Farmer, A., Jul 2011, In : Journal of Affective Disorders. 132, 1-2, p. 112 - 120 9 p.

    Research output: Contribution to journalArticle

  35. Variation in GNB3 predicts response and adverse reactions to antidepressants

    Keers, R., Bonvicini, C., Scassellati, C., Uher, R., Placentino, A., Giovannini, C., Rietschel, M., Henigsberg, N., Kozel, D., Mors, O., Maier, W., Hauser, J., Souery, D., Mendlewicz, J., Schmäl, C., Zobel, A., Larsen, E. R., Szczepankiewicz, A., Kovacic, Z., Elkin, A. & 5 others, Craig, I., McGuffin, P., Farmer, A. E., Aitchison, K. J. & Gennarelli, M., Jul 2011, In : Journal of Psychopharmacology. 25, 7, p. 867 - 874 8 p.

    Research output: Contribution to journalArticle

  36. Costs and outcomes associated with an aripiprazole add-on or switching open-label study in psychosis

    Aitchison, K. J., Mir, A., Shivakumar, K., McAllister, V. D. M., O'Keane, V. & McCrone, P., May 2011, In : Journal of Psychopharmacology. 25, 5, p. 675 - 684 10 p.

    Research output: Contribution to journalArticle

  37. Depressive disorder moderates the effect of the FTO gene on body mass index.

    Rivera, M., Cohen-Woods, S., Kapur, K., Breen, G., Ng, M. Y., Butler, A. W., Craddock, N., Gill, M., Korszun, A., Maier, W., Mors, O., Owen, M. J., Preisig, M., Bergmann, S., Tozzi, F., Rice, J., Rietschel, M., Rucker, J., Schosser, A., Aitchison, K. J. & 5 others, Uher, R., Craig, I. W., Lewis, C. M., Farmer, A. E. & McGuffin, P., 1 Apr 2011, In : Molecular Psychiatry. 17, 6, p. 604-611 8 p.

    Research output: Contribution to journalArticle

  38. Changes in body weight during pharmacological treatment of depression

    Uher, R., Mors, O., Hauser, J., Rietschel, M., Maier, W., Kozel, D., Henigsberg, N., Souery, D., Placentino, A., Keers, R., Gray, J. M., Dernovsek, M. Z., Strohmaier, J., Larsen, E. R., Zobel, A., Szczepankiewicz, A., Kalember, P., Mendlewicz, J., Aitchison, K. J., McGuffin, P. & 1 others, Farmer, A., Apr 2011, In : International Journal of Neuropsychopharmacology . 14, 3, p. 367 - 375 9 p.

    Research output: Contribution to journalArticle

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