King's College London

Research portal

Dr Katherine Morley

  1. Demonstrating trustworthiness when collecting and sharing genomic data: public views across 22 countries

    Milne, R., Morley, K. I., Almarri, M. A., Anwer, S., Atutornu, J., Baranova, E. E., Bevan, P., Cerezo, M., Cong, Y., Costa, A., Critchley, C., Fernow, J., Goodhand, P., Hasan, Q., Hibino, A., Houeland, G., Howard, H. C., Hussain, S. Z., Malmgren, C. I., Izhevskaya, V. L. & 30 others, Jędrzejak, A., Jinhong, C., Kimura, M., Kleiderman, E., Leach, B., Liu, K., Mascalzoni, D., Mendes, Á., Minari, J., Nicol, D., Niemiec, E., Patch, C., Pollard, J., Prainsack, B., Rivière, M., Robarts, L., Roberts, J., Romano, V., Sheerah, H. A., Smith, J., Soulier, A., Steed, C., Stefànsdóttir, V., Tandre, C., Thorogood, A., Voigt, T. H., Wang, N., West, A. V., Yoshizawa, G. & Middleton, A., Dec 2021, In: Genome medicine. 13, 1, p. 92 1 p., 92.

    Research output: Contribution to journalArticlepeer-review

  2. The association of acute alcohol use and dynamic suicide risk with variation in onward care after psychiatric crisis

    Robins, J., Kalk, N., Curtis, V., Pritchard, M., Ross, K. & Morley, K., Mar 2021, In: Drug and Alcohol Review. 40, 3, p. 499-508 10 p., DOI: 10.1111/dar.13231.

    Research output: Contribution to journalArticlepeer-review

  3. Global Public Perceptions of Genomic Data Sharing: What Shapes the Willingness to Donate DNA and Health Data?

    Middleton, A., Milne, R., Almarri, M. A., Anwer, S., Atutornu, J., Baranova, E. E., Bevan, P., Cerezo, M., Cong, Y., Critchley, C., Fernow, J., Goodhand, P., Hasan, Q., Hibino, A., Houeland, G., Howard, H. C., Hussain, S. Z., Malmgren, C. I., Izhevskaya, V. L., Jędrzejak, A. & 29 others, Jinhong, C., Kimura, M., Kleiderman, E., Leach, B., Liu, K., Mascalzoni, D., Mendes, Á., Minari, J., Wang, N., Nicol, D., Niemiec, E., Patch, C., Pollard, J., Prainsack, B., Rivière, M., Robarts, L., Roberts, J., Romano, V., Sheerah, H. A., Smith, J., Soulier, A., Steed, C., Stefànsdóttir, V., Tandre, C., Thorogood, A., Voigt, T. H., West, A. V., Yoshizawa, G. & Morley, K. I., 1 Oct 2020, In: American Journal of Human Genetics. 107, 4, p. 743-752 10 p.

    Research output: Contribution to journalArticlepeer-review

  4. Incidence and treatment costs of severe bacterial infections among people who inject heroin: A cohort study in South London, England

    Lewer, D., Hope, V. D., Harris, M., Kelleher, M., Jewell, A., Pritchard, M., Strang, J. & Morley, K., 1 Jul 2020, In: Drug and alcohol dependence. 212, 108057.

    Research output: Contribution to journalArticlepeer-review

  5. Frequency of health-care utilization by adults who use illicit drugs: a systematic review and meta-analysis

    Lewer, D., Freer, J., King, E., Larney, S., Degenhardt, L., Tweed, E. J., Hope, V. D., Harris, M., Millar, T., Hayward, A., Ciccarone, D. & Morley, K. I., 1 Jun 2020, In: Addiction. 115, 6, p. 1011-1023 13 p.

    Research output: Contribution to journalReview articlepeer-review

  6. Substance use in psychiatric crisis: Relationship to violence

    Kalk, N. J., Robins, J. E., Ross, K. R., Pritchard, M., Lynskey, M. T., Curtis, V. A. & Morley, K. I., 2020, (Accepted/In press) In: Psychological Medicine.

    Research output: Contribution to journalArticlepeer-review

  7. Trust in genomic data sharing among members of the general public in the UK, USA, Canada and Australia

    on behalf of the Participant Values Work Stream of the Global Alliance for Genomics and Health, 1 Dec 2019, In: Human Genetics. 138, 11-12, p. 1237-1246 10 p.

    Research output: Contribution to journalArticlepeer-review

  8. Causes of hospital admission and mortality among 6683 people who use heroin: A cohort study comparing relative and absolute risks

    Lewer, D., Tweed, E. J., Aldridge, R. W. & Morley, K. I., 1 Nov 2019, In: Drug and alcohol dependence. 204, 107525.

    Research output: Contribution to journalArticlepeer-review

  9. Overlap of heritable influences between cannabis use disorder, frequency of use and opportunity to use cannabis: trivariate twin modelling and implications for genetic design

    Hines, L. A., Morley, K. I., Rijsdijk, F., Strang, J., Agrawal, A., Nelson, E. C., Statham, D., Martin, N. G. & Lynskey, M. T., 31 Dec 2018, In: Psychological Medicine. 48, 16, p. 2786-2793 8 p.

    Research output: Contribution to journalArticlepeer-review

  10. Using Clinical Natural Language Processing for Health Outcomes Research: Overview and Actionable Suggestions for Future Advances

    Velupillai, S., Suominen, H., Liakata, M., Roberts, A., Shah, A. D., Morley, K., Osborn, D., Hayes, J. F., Stewart, R., Downs, J., Chapman, W. & Dutta, R., Dec 2018, In: JOURNAL OF BIOMEDICAL INFORMATICS. 88, p. 11-19

    Research output: Contribution to journalArticlepeer-review

  11. Attitudes of publics who are unwilling to donate DNA data for research

    Middleton, A., Milne, R., Thorogood, A., Kleiderman, E., Niemiec, E., Prainsack, B., Farley, L., Bevan, P., Steed, C., Smith, J., Vears, D., Atutornu, J., Howard, H. C. & Morley, K. I., 23 Nov 2018, In: EUROPEAN JOURNAL OF MEDICAL GENETICS.

    Research output: Contribution to journalArticlepeer-review

  12. Addressing substance misuse: a missed opportunity in suicide prevention

    Kalk, N. J., Kelleher, M. J., Curtis, V. & Morley, K. I., 11 Oct 2018, In: Addiction.

    Research output: Contribution to journalArticlepeer-review

  13. 'Your DNA, Your Say': global survey gathering attitudes toward genomics: design, delivery and methods

    Middleton, A., Niemiec, E., Prainsack, B., Bobe, J., Farley, L., Steed, C., Smith, J., Bevan, P., Bonhomme, N., Kleiderman, E., Thorogood, A., Schickhardt, C., Garattini, C., Vears, D., Littler, K., Banner, N., Scott, E., Kovalevskaya, N. V., Levin, E., Morley, K. I. & 1 others, Howard, H. C., 1 Jun 2018, In: Personalized Medicine.

    Research output: Contribution to journalArticlepeer-review

  14. SemEHR: A General-purpose Semantic Search System to Surface Semantic Data from Clinical Notes for Tailored Care, Trial Recruitment and Clinical Research

    Wu, H., Toti, G., Morley, K. I., Ibrahim, Z., Folarin, A., Jackson, R., Kartoglu, I., Agrawal, A., Stringer, C., Gale, D., Gorrell, G., Roberts, A., Broadbent, M., Stewart, R. & Dobson, R. JB., May 2018, In: Journal of the American Medical Informatics Association : JAMIA. 25, 5, p. 530-537

    Research output: Contribution to journalArticlepeer-review

  15. Reply

    Morley, K. I., Ferris, J., Winstock, A. R. & Lynskey, M. T., Nov 2017, In: Pain. 158, 11, p. 2277-2278 2 p.

    Research output: Contribution to journalArticle

  16. SemEHR: surfacing semantic data from clinical notes in electronic health records for tailored care, trial recruitment, and clinical research

    Wu, H., Toti, G., Morley, K. I., Ibrahim, Z., Folarin, A., Kartoglu, I. E., Jackson, R., Agrawal, A., Stringer, C., Gale, D., Gorrell, G., Roberts, A., Broadbent, M., Stewart, R. J. & Dobson, R. J. B., 12 Sep 2017, (Accepted/In press) In: The Lancet.

    Research output: Contribution to journalMeeting abstractpeer-review

  17. Cannabis and Depression: A Twin Model Approach to Co-morbidity

    Smolkina, M., Morley, K. I., Rijsdijk, F., Agrawal, A., Bergin, J. E., Nelson, E. C., Statham, D., Martin, N. G. & Lynskey, M. T., 1 Jul 2017, In: Behavior Genetics. p. 394-404

    Research output: Contribution to journalArticlepeer-review

  18. Polysubstance use and misuse or abuse of prescription opioid analgesics: a multi-level analysis of international data

    Morley, K. I., Ferris, J. A., Winstock, A. R. & Lynskey, M. T., Jun 2017, In: Pain. 158, 6, p. 1138-1144

    Research output: Contribution to journalArticlepeer-review

  19. Are cardiovascular risk factors also associated with the incidence of atrial fibrillation? A systematic review and field synopsis of 23 factors in 32 population based cohorts of 20 million participants

    Allan, V., Honarbakhsh, S., Casas, J-P., Wallace, J., Hunter, R., Schilling, R., Perel, P., Morley, K., Banerjee, A. & Hemingway, H., 23 Feb 2017, In: Thrombosis and Haemostasis.

    Research output: Contribution to journalArticlepeer-review

  20. Onset of opportunity to use cannabis and progression from opportunity to dependence: Are influences consistent across transitions?

    Hines, L. A., Morley, K. I., Strang, J., Agrawal, A., Nelson, E. C., Statham, D., Martin, N. G. & Lynskey, M. T., 1 Mar 2016, In: Drug and alcohol dependence. 160, p. 57-64 8 p.

    Research output: Contribution to journalArticlepeer-review

  21. Prevention, early intervention, harm reduction, and treatment of substance use in young people

    Stockings, E., Hall, W. D., Lynskey, M., Morley, K. I., Reavley, N., Strang, J., Patton, G. & Degenhardt, L., Mar 2016, In: The Lancet Psychiatry. 3, 3, p. 280–296

    Research output: Contribution to journalArticlepeer-review

  22. Why young people's substance use matters for global health

    Hall, W. D., Patton, G., Stockings, E., Weier, M., Lynskey, M., Morley, K. I. & Degenhardt, L., Mar 2016, In: The Lancet Psychiatry. 3, 3, p. 265–279

    Research output: Contribution to journalArticlepeer-review

  23. International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

    Cordell, H. J., Han, Y., Mells, G. F., Li, Y., Hirschfield, G. M., Greene, C. S., Xie, G., Juran, B. D., Zhu, D., Qian, D. C., Floyd, J. A. B., Morley, K. I., Prati, D., Lleo, A., Cusi, D., Gershwin, M. E., Anderson, C. A., Lazaridis, K. N., Invernizzi, P., Seldin, M. F. & 5 others, Sandford, R. N., Amos, C. I., Siminovitch, K. A., Canadian-US PBC Consortium & Srirajaskanthan, R., 24 Sep 2015, In: Nature Communications. 6, 11 p., 8019.

    Research output: Contribution to journalArticlepeer-review

  24. Potential research participants support the return of raw sequence data

    Middleton, A., Wright, C. F., Morley, K. I., Bragin, E., Firth, H. V., Hurles, M. E., Parker, M. & DDD Study, 1 Aug 2015, In: Journal of Medical Genetics. 52, 8, p. 571-574 4 p.

    Research output: Contribution to journalArticlepeer-review

  25. The association between speed of transition from initiation to subsequent use of cannabis and later problematic cannabis use, abuse and dependence

    Hines, L. A., Morley, K. I., Strang, J., Agrawal, A., Nelson, E. C., Statham, D., Martin, N. G. & Lynskey, M. T., 1 Aug 2015, In: Addiction. 110, 8, p. 1311-1320 10 p.

    Research output: Contribution to journalArticlepeer-review

  26. Big biomedical data and cardiovascular disease research: opportunities and challenges

    Denaxas, S. C. & Morley, K. I., 1 Jul 2015, In: European Heart Journal - Quality of Care and Clinical Outcomes. 1, 1, p. 9-16 8 p.

    Research output: Contribution to journalArticlepeer-review

  27. Polysubstance use, mental health and high-risk behaviours: Results from the 2012 Global Drug Survey

    Morley, K. I., Lynskey, M. T., Moran, P., Borschmann, R. & Winstock, A. R., 1 Jul 2015, In: Drug and Alcohol Review. 34, 4, p. 427-437 11 p.

    Research output: Contribution to journalArticlepeer-review

  28. Genetic and environmental interplay in adolescent drug use disorders

    Hines, L. A., Morley, K. I., Mackie, C. & Lynskey, M., Jun 2015, In: Current addiction reports. 2, 2, p. 122-129 8 p.

    Research output: Contribution to journalArticlepeer-review

  29. Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data

    Wright, C. F., Fitzgerald, T. W., Jones, W. D., Clayton, S., McRae, J. F., van Kogelenberg, M., King, D. A., Ambridge, K., Barrett, D. M., Bayzetinova, T., Bevan, A. P., Bragin, E., Chatzimichali, E. A., Gribble, S., Jones, P., Krishnappa, N., Mason, L. E., Miller, R., Morley, K. I., Parthiban, V. & 13 others, Prigmore, E., Rajan, D., Sifrim, A., Swaminathan, G. J., Tivey, A. R., Middleton, A., Parker, M., Carter, N. P., Barrett, J. C., Hurles, M. E., FitzPatrick, D. R., Firth, H. V. & on behalf of the DDD study, 4 Apr 2015, In: Lancet. 385, 9975, p. 1305-1314 10 p.

    Research output: Contribution to journalArticlepeer-review

  30. No expectation to share incidental findings in genomic research

    Middleton, A., Morley, K. I., Bragin, E., Firth, H. V., Hurles, M. E., Wright, C. F., Parker, M. & on behalf of the Deciphering Developmental Disorders Study, 4 Apr 2015, In: Lancet. 385, 9975, p. 1289-1290 2 p.

    Research output: Contribution to journalLetter

  31. Large-scale discovery of novel genetic causes of developmental disorders

    The Deciphering Developmental Disorders Study, 12 Mar 2015, In: NATURE. 519, 7542, p. 223-228

    Research output: Contribution to journalArticlepeer-review

  32. Attitudes of nearly 7000 health professionals, genomic researchers and publics toward the return of incidental results from sequencing research

    Middleton, A., Morley, K. I., Bragin, E., Firth, H. V., Hurles, M. E., Wright, C. F. & Parker, M., 2015, In: European journal of human genetics : EJHG. 9 p.

    Research output: Contribution to journalArticlepeer-review

  33. Possible causes and consequences of reduced perceptions of the risks of using cannabis

    Hall, W. & Morley, K., 2015, In: Clinical toxicology (Philadelphia, Pa.). p. 1-2 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  34. Defining disease phenotypes using national linked electronic health records: A case study of atrial fibrillation

    Morley, K. I., Wallace, J., Denaxas, S. C., Hunter, R. J., Patel, R. S., Perel, P., Shah, A. D., Timmis, A. D., Schilling, R. J. & Hemingway, H., Nov 2014, In: PLOS One. 9, 11, p. 1-10 e110900.

    Research output: Contribution to journalArticlepeer-review

  35. Improving the Transparency of Prognosis Research: The Role of Reporting, Data Sharing, Registration, and Protocols

    Peat, G., Riley, R. D., Croft, P., Morley, K. I., Kyzas, P. A., Moons, K. G. M., Perel, P., Steyerberg, E. W., Schroter, S., Altman, D. G. & Hemingway, H., 8 Jul 2014, In: PL o S Medicine. 11, 7, 8 p., e1001671.

    Research output: Contribution to journalArticlepeer-review

  36. Red Blood Cell Transfusion and Mortality in Trauma Patients: Risk-Stratified Analysis of an Observational Study

    Perel, P., Clayton, T., Altman, D. G., Croft, P., Douglas, I., Hemingway, H., Hingorani, A., Morley, K. I., Riley, R., Timmis, A., Van der Windt, D., Roberts, I. & for the PROGRESS Partnership, 17 Jun 2014, In: PL o S Medicine. 11, 6, 9 p., e1001664.

    Research output: Contribution to journalArticlepeer-review

  37. Online questionnaire development: Using film to engage participants and then gather attitudes towards the sharing of genomic data

    Middleton, A., Bragin, E., Morley, K. I., Parker, M. & DDD Study, Mar 2014, In: SOCIAL SCIENCE RESEARCH. 44, p. 211-223 13 p.

    Research output: Contribution to journalArticlepeer-review

  38. Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets

    Jostins, L., Morley, K. I. & Barrett, J. C., Jun 2011, In: European journal of human genetics : EJHG. 19, 6, p. 662-6 5 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  39. Systematic review of early cardiometabolic outcomes of the first treated episode of psychosis

    Foley, D. L. & Morley, K. I., Jun 2011, In: Archives of General Psychiatry. 68, 6, p. 609-616 8 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  40. Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

    Mells, G. F., Floyd, J. A. B., Morley, K., Cordell, H. J., Franklin, C. S., Shin, S-Y., Heneghan, M. A., Neuberger, J. M., Donaldson, P. T., Day, D. B., Ducker, S. J., Muriithi, A. W., Wheater, E. F., Hammond, C. J., Dawwas, M. F., Jones, D. E., Peltonen, L., Alexander, G. J., Sandford, R. N., Anderson, C. A. & 1 others, UK PBC Consortium, Apr 2011, In: Nature Genetics. 43, 4, p. 329-332 4 p.

    Research output: Contribution to journalLetterpeer-review

  41. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

    Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D'Amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagace, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Buening, C. & 93 others, Colombel, J-F., Denson, L. A., De Vos, M., Dubinsky, M., Edwards, C., Ellinghaus, D., Fehrmann, R. S. N., Floyd, J. A. B., Florin, T., Franchimont, D., Franke, L., Georges, M., Glas, J., Glazer, N. L., Guthery, S. L., Haritunians, T., Hayward, N. K., Hugot, J-P., Jobin, G., Laukens, D., Lawrance, I., Lemann, M., Levine, A., Libioulle, C., Louis, E., McGovern, D. P., Milla, M., Montgomery, G. W., Morley, K., Mowat, C., Ng, A., Newman, W., Ophoff, R. A., Papi, L., Palmieri, O., Peyrin-Biroulet, L., Panes, J., Phillips, A., Prescott, N. J., Proctor, D. D., Roberts, R., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Schumm, P., Seibold, F., Sharma, Y., Simms, L. A., Seielstad, M., Steinhart, A. H., Targan, S. R., van den Berg, L. H., Vatn, M., Verspaget, H., Walters, T., Wijmenga, C., Wilson, D. C., Westra, H-J., Xavier, R. J., Zhao, Z. Z., Ponsioen, C. Y., Andersen, V., Torkvist, L., Gazouli, M., Anagnou, N. P., Karlsen, T. H., Kupcinskas, L., Sventoraityte, J., Mansfield, J. C., Kugathasan, S., Silverberg, M. S., Halfvarson, J., Rotter, J. I., Mathew, C. G., Griffiths, A. M., Gearry, R., Ahmad, T., Brant, S. R., Chamaillard, M., Satsangi, J., Cho, J. H., Schreiber, S., Daly, M. J., Barrett, J. C., Parkes, M., Annese, V., Hakonarson, H., Radford-Smith, G., Duerr, R. H., Vermeire, S., Weersma, R. K. & Rioux, J. D., Mar 2011, In: Nature Genetics. 43, 3, p. 246 - U94 7 p.

    Research output: Contribution to journalArticlepeer-review

  42. Being more realistic about the public health impact of genomic medicine

    Hall, W. D., Mathews, R. & Morley, K. I., 12 Oct 2010, In: PL o S Medicine. 7, 10, p. N/A 4 p., e1000347.

    Research output: Contribution to journalArticlepeer-review

  43. Major depression and the metabolic syndrome

    Foley, D. L., Morley, K. I., Madden, P. A. F., Heath, A. C., Whitfield, J. B. & Martin, N. G., Aug 2010, In: TWIN RESEARCH AND HUMAN GENETICS. 13, 4, p. 347-358 12 p.

    Research output: Contribution to journalArticlepeer-review

  44. Multiple common variants for celiac disease influencing immune gene expression

    Dubois, P. C. A., Trynka, G., Franke, L., Hunt, K. A., Romanos, J., Curtotti, A., Zhernakova, A., Heap, G. A. R., Adany, R., Aromaa, A., Bardella, M. T., van den Berg, L. H., Bockett, N. A., de la Concha, E. G., Dema, B., Fehrmann, R. S. N., Fernandez-Arquero, M., Fiatal, S., Grandone, E., Green, P. M. & 47 others, Groen, H. J. M., Gwilliam, R., Houwen, R. H. J., Hunt, S. E., Kaukinen, K., Kelleher, D., Korponay-Szabo, I., Kurppa, K., MacMathuna, P., Maki, M., Mazzilli, M. C., McCann, O. T., Mearin, M. L., Mein, C. A., Mirza, M. M., Mistry, V., Mora, B., Morley, K., Mulder, C. J., Murray, J. A., Nunez, C., Oosterom, E., Ophoff, R. A., Polanco, I., Peltonen, L., Platteel, M., Rybak, A., Salomaa, V., Schweizer, J. J., Sperandeo, M. P., Tack, G. J., Turner, G., Veldink, J. H., Verbeek, W. H. M., Weersma, R. K., Wolters, V. M., Urcelay, E., Cukrowska, B., Greco, L., Neuhausen, S. L., McManus, R., Barisani, D., Deloukas, P., Barrett, J. C., Saavalainen, P., Wijmenga, C. & van Heel, D. A., Apr 2010, In: Nature Genetics. 42, 4, p. 295 - U42 8 p.

    Research output: Contribution to journalArticlepeer-review

  45. Socio-economic status and survival from breast cancer for young, Australian, urban women

    Morley, K. I., Milne, R. L., Giles, G. G., Southey, M. C., Apicella, C., Hopper, J. L. & Phillips, K-A., Apr 2010, In: Australian and New Zealand Journal of Public Health. 34, 2, p. 200-205 6 p., N/A.

    Research output: Contribution to journalArticlepeer-review

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