King's College London

Research portal

Dr Kathryn Lester

  1. Therapygenetic effects of 5-HTTLPR on cognitive-behavioral therapy in anxiety disorders: A meta-analysis

    Schiele, M. A., Reif, A., Lin, J., Alpers, G. W., Andersson, E., Andersson, G., Arolt, V., Bergström, J., Carlbring, P., Eley, T. C., Esquivel, G., Furmark, T., Gerlach, A. L., Hamm, A., Helbig-Lang, S., Hudson, J. L., Lang, T., Lester, K. J., Lindefors, N., Lonsdorf, T. B., & 11 othersPauli, P., Richter, J., Rief, W., Roberts, S., Rück, C., Schruers, K. R. J., Thiel, C., Wittchen, H. U., Domschke, K., Weber, H. & Lueken, U., Mar 2021, In: European Neuropsychopharmacology. 44, p. 105-120 16 p.

    Research output: Contribution to journalArticlepeer-review

  2. Large-scale remote fear conditioning: demonstration of associations with anxiety using the FLARe smartphone app

    McGregor, T., Purves, K., Constantinou, E., Baas, J., Barry, T., Craske, M. G., Carr, E., Lester, K., Palaiologou, E., Breen, G., Young, K. & Eley, T., 14 Feb 2021, (Accepted/In press) In: Depression and Anxiety.

    Research output: Contribution to journalArticlepeer-review

  3. Validating the use of a smartphone app for remote administration of a fear conditioning paradigm

    Purves, K. L., Constantinou, E., McGregor, T., Lester, K. J., Barry, T. J., Treanor, M., Sun, M., Margraf, J., Craske, M. G., Breen, G. & Eley, T. C., 1 Dec 2019, In: Behaviour Research and Therapy. 123, 103475.

    Research output: Contribution to journalArticlepeer-review

  4. The utility of the SCAS-C/P to detect specific anxiety disorders among clinically anxious children

    Reardon, T., Creswell, C., Lester, K., Arendt, K., Blatter-Meunier, J., Bögels, S. M., Coleman, J. R. I., Cooper, P., Heiervang, E., Herren, C., Hogendoorn, S. M., Hudson, J. L., Keers, R., Lyneham, H. J., Marin, C., Nauta, M., Rapee, R. M., Roberts, S., Schneider, S., Silverman, W. K., & 4 othersThastum, M., Thirlwall, K., Wergeland, G. J. & Eley, T. C., 31 Dec 2018, (Accepted/In press) In: Psychological Assessment.

    Research output: Contribution to journalArticlepeer-review

  5. DNA methylation of FKBP5 and response to exposure-based psychological therapy

    Roberts, S., Keers, R., Breen, G., Coleman, J. R. I., Jöhren, P., Kepa, A., Lester, K. J., Margraf, J., Scheider, S., Teismann, T., Wannemüller, A., Eley, T. C. & Wong, C. C. Y., 18 Oct 2018, (E-pub ahead of print) In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics.

    Research output: Contribution to journalArticlepeer-review

  6. Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

    Culverhouse, R. C., Saccone, N. L., Horton, A. C., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M., Araya, R., & 64 othersBowes, L., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J-J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Zu Schwabedissen, H. M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Tian, Y., Toben, C., Van der Auwera, S., Wainwright, N., Willemsen, G., Anderson, I. M., Arolt, V., Åslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., de Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Laucht, M., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J. I., Breslau, N. & Bierut, L. J., 1 Jan 2018, In: Molecular Psychiatry. 23, 1, p. 133-142

    Research output: Contribution to journalArticlepeer-review

  7. Genome-wide expression and response to exposure-based psychological therapy for anxiety disorders

    Roberts, S., Wong, C. C. Y., Breen, G., Coleman, J. R. I., De Jong, S., Jöhren, P., Keers, R., Curtis, C., Lee, S. H., Margraf, J., Schneider, S., Teismann, T., Wannemüller, A., Lester, K. J. & Eley, T. C., 29 Aug 2017, (E-pub ahead of print) In: Translational psychiatry. 7, 8, 1219.

    Research output: Contribution to journalArticlepeer-review

  8. The role of KIBRA in reconstructive episodic memory

    Zlomuzica, A., Preusser, F., Roberts, S. L., Woud, M. L., Lester, K. J., Dere, E., Eley, T. C. & Margraf, J., 28 Aug 2017, (Accepted/In press) In: Molecular Medicine.

    Research output: Contribution to journalArticlepeer-review

  9. The dopamine D2 receptor mediates approach-avoidance tendencies in smokers

    Zlomuzica, A., Machulska, A., Roberts, S., von Glischinski, M., Rinck, M., Lester, K. J., Eley, T. C. & Margraf, J., 31 Mar 2017, (E-pub ahead of print) In: European Archives Of Psychiatry And Clinical Neuroscience. p. 1-8 8 p.

    Research output: Contribution to journalArticlepeer-review

  10. Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders

    Lester, K. J., Coleman, J., Roberts, S., Keers, R., Breen, G., Bögels, S., Creswell, C., Hudson, J. L., Mckinnon, A., Nauta, M., Rapee, R. M., Schneider, S., Silverman, W. K., Thastum, M., Waite, P., Wergeland, G. J. H. & Eley, T. C., 27 Jun 2016, (E-pub ahead of print) In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics.

    Research output: Contribution to journalArticlepeer-review

  11. A genome-wide test of the differential susceptibility hypothesis reveals a genetic predictor of differential response to psychological treatments for child anxiety disorders

    Keers, R., Coleman, J., Lester, K. J., Roberts, S. L., Breen, G. D., Thastum, M., Bögels, S., Schneider, S., Heiervang, E., Meiser-Stedman, R., Nauta, M., Creswell, C., Thirlwall, K., Rapee, R. M., Hudson, J. L., Lewis, C. M., Plomin, R. J. & Eley, T. C., 5 Apr 2016, In: Psychotherapy and Psychosomatics. 85, 3, p. 146-158 13 p.

    Research output: Contribution to journalArticlepeer-review

  12. Genome-wide association study of response to cognitive behavioural therapy in children with anxiety disorders

    Coleman, J., Lester, K. J., Keers, R., Roberts, S., Curtis, C. J., Arendt, K., Bogels, S., Cooper, P., Creswell, C., Dalgleish, T., Hartman, C., Heiervang, E., Hötzel, K., Hudson, J. L., In-Albon, T., Lavallee, K., Lyneham, H., Marin, C., Meiser-Stedman, R., Morris, T., & 11 othersNauta, M., Rapee, R. M., Schneider, S., Schneider, S. C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J., Breen, G. D. & Eley, T. C., 17 Mar 2016, (E-pub ahead of print) In: British Journal of Psychiatry. 208, 3

    Research output: Contribution to journalArticlepeer-review

  13. Cognitive Vulnerabilities for Depression and Anxiety in Childhood: Specificity of Anxiety Sensitivity and Rumination

    Brown, H. M., Meiser-Stedman, R., Woods, H. & Lester, K. J., 1 Jan 2016, In: Behavioural and Cognitive Psychotherapy. 44, 1, p. 30-42

    Research output: Contribution to journalArticlepeer-review

  14. HPA axis related genes and response to psychological therapies: Genetics and epigenetics

    Roberts, S., Keers, R., Lester, K. J., Coleman, J., Breen, G., Arendt, K., Blatter-Meunier, J., Cooper, P., Creswell, C., Fjermestad, K., Havik, O. E., Herren, C., Hogendoorn, S. M., Hudson, J. L., Krause, K., Lyneham, H. J., Morris, T., Nauta, M., Rapee, R. M., Rey, Y., & 8 othersSchneider, S., Schneider, S. C., Silverman, W. K., Thastum, M., Thirlwall, K., Waite, P., Eley, T. C. & Wong, C. C. Y., 7 Oct 2015, (E-pub ahead of print) In: Depression and Anxiety. 10 p.

    Research output: Contribution to journalArticlepeer-review

  15. Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders

    Lester, K., Roberts, S., Keers, R., Coleman, J., Breen, G., Wong, C., Xu, X., Arendt, K., Blatter-Meunier, J., Bögels, S., Cooper, P., Creswell, C., Heiervang, E., Herren, C., Hogendoorn, S., Hudson, J., Krause, K., Lyneham, H., McKinnon, A., Morris, T., & 12 othersNauta, M., Rapee, R., Rey, Y., Schneider, S., Schneider, S., Silverman, W., Smith, P., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J. & Eley, T., 20 Aug 2015, In: British Journal of Psychiatry. 7 p.

    Research output: Contribution to journalArticlepeer-review

  16. Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study

    Hudson, J., Keers, R., Roberts, S., Coleman, J., Breen, G., Arendt, K., Bogels, S., Cooper, P., Creswell, C., Hartman, C. A., Heiervang, E., Hotzel, K., In-Albon, T., Lavallee, K., Lyneham, H. J., Marin, C. E., McKinnon, A., Meiser-Stedman, R., Morris, T., Nauta, M., & 10 othersRapee, R., Schneider, S., Schneider, S., Silverman, W., Thastum, M., Thirlwall, K., Waite, P., Wergeland, G. J., Lester, K. & Eley, T., 1 Jun 2015, In: Journal of the American Academy of Child and Adolescent Psychiatry. 54, 6, p. 454–463

    Research output: Contribution to journalArticlepeer-review

  17. Epigenome-wide DNA methylation analysis of monozygotic twins discordant for diurnal preference

    Wong, C. C. Y., Parsons, M. J., Lester, K. J., Burrage, J., Eley, T. C., Mill, J., Dempster, E. & Gregory, A., 2015, (Accepted/In press) In: TWIN RESEARCH AND HUMAN GENETICS.

    Research output: Contribution to journalArticlepeer-review

  18. Genome-wide Methylomic Analysis of Monozygotic Twins Discordant for Adolescent Depression

    Dempster, E. L., Wong, C., Lester, K. J., Burrage, J., Gregory, A. M., Mill, J. & Eley, T. C., 15 Dec 2014, In: Biological psychiatry. 76, 12, p. 977-983 7 p.

    Research output: Contribution to journalArticlepeer-review

  19. Serotonin Transporter Methylation and Response to Cognitive Behaviour Therapy in Children with Anxiety Disorders

    Roberts, S., Lester, K. J., Hudson, J. L., Rapee, R. M., Creswell, C., Cooper, P. J., Thirlwall, K. J., Coleman, J. R. I., Breen, G., Wong, C. C. Y. & Eley, T. C., Sep 2014, In: Translational psychiatry. 4, 5 p., e444.

    Research output: Contribution to journalArticlepeer-review

  20. Paediatric Obsessive-Compulsive Disorder and Depressive Symptoms: Clinical Correlates and CBT Treatment Outcomes

    Brown, H. M., Lester, K. J., Jassi, A., Heyman, I. & Krebs, G., 1 Jul 2014, In: Journal of Abnormal Child Psychology. 43, 5, p. 933-942 10 p.

    Research output: Contribution to journalArticlepeer-review

  21. Psychometric properties of reaction time based experimental paradigms measuring anxiety-related information-processing biases in children

    Brown, H. M., Eley, T. C., Broeren, S., Macleod, C., Rinck, M., Hadwin, J. A. & Lester, K. J., Jan 2014, In: Journal of Anxiety Disorders. 28, 1, p. 97-107 11 p.

    Research output: Contribution to journalArticlepeer-review

  22. Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures

    Parsons, M. J., Lester, K. J., Barclay, N. L., Archer, S. N., Nolan, P. M., Eley, T. C. & Gregory, A. M., 2014, (E-pub ahead of print) In: Journal of Sleep Research.

    Research output: Contribution to journalArticlepeer-review

  23. Predicting outcomes following cognitive behaviour therapy in child anxiety disorders: the influence of genetic, demographic and clinical information

    Hudson, J. L., Lester, K. J., Lewis, C. M., Tropeano, M., Creswell, C., Collier, D. A., Cooper, P., Lyneham, H. J., Morris, T., Rapee, R. M., Roberts, S., Donald, J. A. & Eley, T. C., Oct 2013, In: Journal of Child Psychology and Psychiatry. 54, 10, p. 1086-1094 9 p.

    Research output: Contribution to journalArticlepeer-review

  24. Replication of Genome-Wide association studies (GWAS) loci for sleep in the British G1219 cohort

    Parsons, M. J., Lester, K. J., Barclay, N. L., Nolan, P. M., Eley, T. C. & Gregory, A. M., Jul 2013, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 162, 5, p. 431-438 8 p.

    Research output: Contribution to journalArticlepeer-review

  25. Relevance Is in the Eye of the Beholder: Attentional Bias to Relevant Stimuli in Children

    Broeren, S. & Lester, K. J., Apr 2013, In: EMOTION. 13, 2, p. 262-269 8 p.

    Research output: Contribution to journalArticlepeer-review

  26. Therapygenetics: Predicting response to CBT in child anxiety from specific genetic markers

    Eley, T., Hudson, J., Creswell, C., Tropeano, M., Lester, K., Cooper, P., Farmer, A., Lewis, C., Lyneham, H., Rapee, R., Uher, R., Zavos, H. & Collier, D., Nov 2012, In: Behavior Genetics. 42, 6, p. 932-932 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  27. Maternal anxiety and cognitive biases towards threat in their own and their child's environment

    Lester, K. J., Field, A. P. & Cartwright-hatton, S., Oct 2012, In: Journal of Family Psychology. 26, 5, p. 756-766

    Research output: Contribution to journalArticlepeer-review

  28. Neurotrophic gene polymorphisms and response to psychological therapy

    Lester, K., Hudson, J. L., Tropeano, M., Creswell, C., Collier, D., Farmer, A., Lyneham, H. J., Rapee, R. M. & Eley, T., 1 May 2012, In: Translational psychiatry. 2, e108.

    Research output: Contribution to journalArticlepeer-review

  29. Therapygenetics: the 5HTTLPR and response to psychological therapy

    Eley, T. C., Hudson, J. L., Creswell, C., Tropeano, M., Lester, K. J., Cooper, P., Farmer, A., Lewis, C. M., Lyneham, H. J., Rapee, R. M., Uher, R., Zavos, H. M. S. & Collier, D. A., Mar 2012, In: Molecular Psychiatry. 17, 3, p. 236 - 237 2 p.

    Research output: Contribution to journalLetterpeer-review

  30. But what about the Empress of Racnoss? The allocation of attention to spiders and Doctor Who in a visual search task is predicted by fear and expertise

    Purkis, H. M., Lester, K. J. & Field, A. P., Dec 2011, In: EMOTION. 11, 6, p. 1484-1488

    Research output: Contribution to journalArticlepeer-review

  31. Training children to approach or avoid novel animals: Effects on self-reported attitudes and fear beliefs and information-seeking behaviors

    Huijding, J., Muris, P., Lester, K. J., Field, A. P. & Joosse, G., 1 Oct 2011, In: Behaviour Research and Therapy. 49, 10, p. 606-613

    Research output: Contribution to journalArticlepeer-review

  32. Modifying cognitive errors promotes cognitive well being: A new approach to bias modification

    Lester, K. J., Mathews, A., Davison, P. S., Burgess, J. L. & Yiend, J., Sep 2011, In: Journal of Behavior Therapy and Experimental Psychiatry. 42, 3, p. 298 - 308 11 p.

    Research output: Contribution to journalArticlepeer-review

  33. Experimental modification of interpretation bias regarding social and animal fear in children

    Lester, K. J., Field, A. P. & Muris, P., Jun 2011, In: Journal of Anxiety Disorders. 25, 5, p. 697-705

    Research output: Contribution to journalArticlepeer-review

  34. Are children's own interpretations of ambiguous situations based on how they perceive their mothers have interpreted ambiguous situations for them in the past?

    Lester, K. J., Seal, K., Nightingale, Z. C. & Field, A. P., Jan 2010, In: Journal of Anxiety Disorders. 24, 1, p. 102-108

    Research output: Contribution to journalArticlepeer-review

  35. Long term outcome of primary care depression

    Yiend, J., Paykel, E., Merritt, R., Lester, K., Doll, H. & Burns, T., 1 Nov 2009, In: Journal of Affective Disorders. 118, 1-3, p. 79-86 8 p.

    Research output: Contribution to journalArticlepeer-review

  36. Short-term serotonergic but not noradrenergic antidepressant administration reduces attentional vigilance to threat in healthy volunteers

    Murphy, S. E., Yiend, J., Lester, K. J., Cowen, P. J. & Harmer, C. J., Mar 2009, In: International Journal of Neuropsychopharmacology . 12, 2, p. 169-179 11 p.

    Research output: Contribution to journalArticlepeer-review

  37. Do anxious parents interpretive biases towards threat extend into their child's environment?

    Lester, K. J., Field, A. P., Oliver, S. & Cartwright-hatton, S., 1 Feb 2009, In: Behaviour Research and Therapy. 47, 2, p. 170-174 5 p.

    Research output: Contribution to journalArticlepeer-review

  38. Evaluative conditioning: missing, presumed dead

    Field, A. P., Lascelles, K. R. R., Lester, K. J., Askew, C. & Davey, G. C. L., 1 Jun 2008, In: Netherlands Journal of Psychology. 64, 2, p. 46-64 19 p.

    Research output: Contribution to journalArticlepeer-review

  39. Communicating risk information in genetic counseling: An observational study

    Michie, S., Lester, K., Pinto, J. & Marteau, T. M., 1 Oct 2005, In: Health Education and Behavior. 32, 5, p. 589-598 10 p.

    Research output: Contribution to journalArticlepeer-review

  40. Words matter: increasing the implementation of clinical guidelines

    Michie, S. & Lester, K., 1 Oct 2005, In: QUALITY AND SAFETY IN HEALTH CARE. 14, 5, p. 367-370 4 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  41. A funding model for a psychological service to plastic and reconstructive surgery in UK practice

    Clarke, A., Lester, K. J., Withey, S. J. & Butler, P. E. M., 1 Jul 2005, In: British Journal of Plastic Surgery. 58, 5, p. 708-713 6 p., N/A.

    Research output: Contribution to journalArticlepeer-review

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