Kenneth Bruce

Webb, K., Zain, N. M. M., Stewart, I., Fogarty, A., Nash, E. F., Whitehouse, J. L., Smyth, A. R., Lilley, A. K., Knox, A., Williams, P., Cámara, M., Bruce, K. & Barr, H. L., 1 Feb 2022, In: Journal of medical microbiology. 71, 2, 001481.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Rifaximin reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial

Patel, V. C., Lee, S., McPhail, M. J. W., Zamalloa, A., Witherden, E., Stoy, S., Vijay, G. M., Huang, X., Gencer, S., Coen, M., Tranah, T., Wendon, J., Bruce, K., Ehrlich, D., Edwards, L. A., Shoaie, S. & Shawcross, D. L., Feb 2022, In: Journal of Hepatology. 76, 2, p. 332-342 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

112 Citations (Scopus)

2021

2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis

Zain, N. M. M., Webb, K., Stewart, I., Halliday, N., Barrett, D. A., Nash, E. F., Whitehouse, J. L., Honeybourne, D., Smyth, A. R., Forrester, D. L., Knox, A. J., Williams, P., Fogarty, A., Cámara, M., Bruce, K. D. & Barr, H. L., Oct 2021, In: Journal of Medical Microbiology. 70, 10, 001420.

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Gut microbiota development during infancy: Impact of introducing allergenic foods

Marrs, T., Jo, J. H., Perkin, M. R., Rivett, D. W., Witney, A. A., Bruce, K. D., Logan, K., Craven, J., Radulovic, S., Versteeg, S. A., van Ree, R., McLean, W. H. I., Strachan, D. P., Lack, G., Kong, H. H. & Flohr, C., Feb 2021, In: Journal of Allergy and Clinical Immunology. 147, 2, p. 613-621.e9

Research output: Contribution to journal › Article › peer-review

Open Access

66 Citations (Scopus)

Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis

Webb, K., Cámara, M., Zain, N. M. M., Halliday, N., Bruce, K. D., Nash, E. F., Whitehouse, J. L., Knox, A., Forrester, D., Smyth, A. R., Williams, P., Fogarty, A. & Barr, H. L., 2021, (Accepted/In press) In: Journal Of Cystic Fibrosis.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Peripheral airways type 2 inflammation, neutrophilia and microbial dysbiosis in severe asthma

Azim, A., Green, B., Lau, L., Rupani, H., Jayasekera, N., Bruce, K. & Howarth, P., Jul 2021, In: Allergy: European Journal of Allergy and Clinical Immunology. 76, 7, p. 2070-2078 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

2020

Amoebae in Chronic, Polymicrobial Endodontic Infections Are Associated with Altered Microbial Communities of Increased Virulence

Koller, G., Foschi, F., Witherden, L., Mitchell, P., Bruce, K. & Mannocci, F., 19 Nov 2020, In: Journal of Clinical Medicine. J. Clin. Med. 2020, 9(11), 3700;

Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

75 Downloads (Pure)

Antibiotic-in-cyclodextrin-in-liposomes: formulation development and interactions with model bacterial membranes

Vandera, K-K. A., Picconi, P., Valero, M., González-Gaitano, G., Woods, A., Zain, N. M., Bruce, K., Clifton, L. A., Skoda, M. W. A., Rahman, K. M., Harvey, R. D. & Dreiss, C., 6 Jul 2020, In: Molecular Pharmaceutics. 17, 7, p. 2354-2369 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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11 Citations (Scopus)

256 Downloads (Pure)

Lung function and microbiota diversity in cystic fibrosis

Cuthbertson, L., Walker, A. W., Oliver, A. E., Rogers, G. B., Rivett, D. W., Hampton, T. H., Ashare, A., Elborn, J. S., De Soyza, A., Carroll, M. P., Hoffman, L. R., Lanyon, C., Moskowitz, S. M., O'Toole, G. A., Parkhill, J., Planet, P. J., Teneback, C. C., Tunney, M. M., Zuckerman, J. B., Bruce, K. D., & 1 othersVan Der Gast, C. J., 2 Apr 2020, In: Microbiome. 8, 1, 45.

Research output: Contribution to journal › Article › peer-review

Open Access

147 Citations (Scopus)

The airways microbiome of individuals with asthma treated with high and low doses of inhaled corticosteroids

Martin, M. J., Zain, N. M. M., Hearson, G., Rivett, D. W., Koller, G., Wooldridge, D. J., Rose, G., Gharbia, S. E., Forbes, B., Bruce, K. D. & Harrison, T. W., Dec 2020, In: PLoS ONE. 15, 12 December, e0244681.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Citations (Scopus)

The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo.

Amison, R. T., Faure, M-E. Y. L., O'Shaughnessy, B. G., Bruce, K., Hu, Y., Coates, A. & Page, C. P., 1 Apr 2020, In: Pulmonary pharmacology & therapeutics. 61, 101884.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

2019

Circadian leaf movements facilitate overtopping of neighbors

Woodley of Menie, M. A., Pawlik, P., Webb, M. T., Bruce, K. D. & Devlin, P. F., 1 Sept 2019, In: Progress in Biophysics and Molecular Biology. 146, p. 104-111 8 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Selection and assembly of indigenous bacteria and methanogens from spent metalworking fluids and their potential as a starting culture in a fluidized bed reactor

Vyrides, I., Rivett, D. W., Bruce, K. D. & Lilley, A. K., 1 Nov 2019, In: Microbial Biotechnology. 12, 6, p. 1302-1312 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

2018

Clinical and symptom scores are significantly correlated with fecal microbiota features in patients with symptomatic uncomplicated diverticular disease: A pilot study

Kvasnovsky, C. L., Leong, L. E. X., Choo, J. M., Abell, G. C. J., Papagrigoriadis, S., Bruce, K. D. & Rogers, G. B., 1 Jan 2018, In: European Journal of Gastroenterology and Hepatology. 30, 1, p. 107-112 6 p.

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Self-Limiting versus Conventional Caries Removal: A Randomized Clinical Trial

Ali, A. H., Koller, G., Foschi, F., Andiappan, M., Bruce, K. D., Banerjee, A. & Mannocci, F., 2018, In: Journal of Dental Research.

Research output: Contribution to journal › Article › peer-review

Open Access

File

33 Citations (Scopus)

641 Downloads (Pure)

2017

Bacterial Contamination of Endodontic Materials before and after Clinical Storage

Saeed, M., Koller, G., Niazi, S., Patel, S., Mannocci, F., Bruce, K. & Foschi, F., Nov 2017, In: JOURNAL OF ENDODONTICS. 43, 11, p. 1852-1856 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

12 Citations (Scopus)

274 Downloads (Pure)

Contributions of Composition and Interactions to Bacterial Respiration Are Reliant on the Phylogenetic Similarity of the Measured Community

Rivett, D. W., Lilley, A. K., Connett, G. J., Carroll, M. P., Legg, J. P. & Bruce, K. D., 27 Apr 2017, (E-pub ahead of print) In: MICROBIAL ECOLOGY. p. 1-4 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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3 Citations (Scopus)

172 Downloads (Pure)

Divergent Relationships between Fecal Microbiota and Metabolome following Distinct Antibiotic-Induced Disruptions

Choo, J. M., Kanno, T., Zain, N. M., Leong, L. E. X., Abell, G. C. J., Keeble, J. E., Bruce, K. D., Mason, A. J. & Rogers, G. B., 8 Feb 2017, In: mSphere. 2, 16 p., 2:e00005-17.

Research output: Contribution to journal › Article › peer-review

Open Access

File

35 Citations (Scopus)

226 Downloads (Pure)

Fungal and Bacterial Diversity of Airway Microbiota in Adults with Cystic Fibrosis: Concordance Between Conventional Methods and Ultra-Deep Sequencing, and Their Practical use in the Clinical Laboratory

Botterel, F., Angebault, C., Cabaret, O., Stressmann, F. A., Costa, J-M., Wallet, F., Wallaert, B., Bruce, K. & Delhaes, L., 1 Aug 2017, (E-pub ahead of print) In: Mycopathologia. p. 1-13 13 p.

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

Howlin, R. P., Cathie, K., Hall-Stoodley, L., Cornelius, V., Duignan, C., Allan, R. N., Fernandez, B. O., Barraud, N., Bruce, K. D., Jefferies, J., Kelso, M., Kjelleberg, S., Rice, S. A., Rogers, G. B., Pink, S., Smith, C., Sukhtankar, P. S., Salib, R., Legg, J., Carroll, M., & 7 othersDaniels, T., Feelisch, M., Stoodley, P., Clarke, S. C., Connett, G., Faust, S. N. & Webb, J. S., 6 Sept 2017, In: Molecular Therapy. 25, 9, p. 2104-2116 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

157 Citations (Scopus)

2016

Isolation of Propionibacterium acnes among the microbiota of primary endodontic infections with and without intraoral communication

Niazi, S. A., Al Kharusi, H. S., Patel, S., Bruce, K., Beighton, D., Foschi, F. & Mannocci, F., 9 Feb 2016, (E-pub ahead of print) In: CLINICAL ORAL INVESTIGATIONS.

Research output: Contribution to journal › Article › peer-review

Open Access

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13 Citations (Scopus)

205 Downloads (Pure)

Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention

Cuthbertson, L., Rogers, G. B., Walker, A. W., Oliver, A., Green, L. E., Daniels, T. W. V., Carroll, M. P., Parkhill, J., Bruce, K. D. & Van Der Gast, C. J., 30 May 2016, In: Isme Journal. 10, 5, p. 1081-1091

Research output: Contribution to journal › Article › peer-review

Open Access

File

86 Citations (Scopus)

194 Downloads (Pure)

2015

Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice

Rogers, G. B., Kozlowska, J., Keeble, J., Metcalfe, K., Fao, M., Dowd, S. E., Mason, A. J., McGuckin, M. A. & Bruce, K. D., 2015, In: Scientific Reports. 4, 5 p., 5437.

Research output: Contribution to journal › Article › peer-review

Open Access

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45 Citations (Scopus)

113 Downloads (Pure)

Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses

Cuthbertson, L., Rogers, G. B., Walker, A. W., Oliver, A., Hoffman, L. R., Carroll, M. P., Parkhill, J., Bruce, K. D. & van der Gast, C. J., 1 Jul 2015, In: Journal Of Cystic Fibrosis. 14, 4, p. 464-467 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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29 Citations (Scopus)

234 Downloads (Pure)

In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery

Woods, A., Patel, A., Spina, D., Riffo-Vasquez, Y., Babin-Morgan, A., De Rosales, R. T. M., Sunassee, K., Clark, S., Collins, H., Bruce, K., Dailey, L. A. & Forbes, B., 28 Jul 2015, In: JOURNAL OF CONTROLLED RELEASE. 210, p. 1-9 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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75 Citations (Scopus)

152 Downloads (Pure)

Republished: Respiratory microbiota: Addressing clinical questions, informing clinical practice

Rogers, G. B., Shaw, D., Marsh, R. L., Carroll, M. P., Serisier, D. J. & Bruce, K. D., 8 Jan 2015, In: Postgraduate Medical Journal. 91, 1078, p. 463-470 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2 Citations (Scopus)

223 Downloads (Pure)

Respiratory microbiota: Addressing clinical questions, informing clinical practice

Rogers, G. B., Shaw, D., Marsh, R. L., Carroll, M. P., Serisier, D. J. & Bruce, K. D., 1 Jan 2015, In: Thorax. 70, 1, p. 74-81 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

72 Citations (Scopus)

175 Downloads (Pure)

2014

A novel microbiota stratification system predicts future exacerbations in bronchiectasis

Rogers, G. B., Zain, N. M. M., Bruce, K. D., Burr, L. D., Chen, A. C., Rivett, D. W., McGuckin, M. A. & Serisier, D. J., May 2014, In: Annals of the American Thoracic Society. 11, 4, p. 496-503 8 p.

Research output: Contribution to journal › Article › peer-review

181 Citations (Scopus)

Combined Systems Approaches Reveal Highly Plastic Responses to Antimicrobial Peptide Challenge in Escherichia coli

Kozlowska, J., Vermeer, L., Rogers, G., Rehnnuma, N., Amos, S-B., Koller, G., McArthur, M., Bruce, K. & Mason, J., 1 May 2014, In: PLoS Pathogens. 10, 5, 14 p., e1004104.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Citations (Scopus)

Environmentally determined differences in the murine lung microbiota and their relation to alveolar architecture

Yun, Y., Srinivas, G., Kuenzel, S., Linnenbrink, M., Alnahas, S., Bruce, K. D., Steinhoff, U., Baines, J. F. & Schaible, U. E., 3 Dec 2014, In: PL o S One . 9, 12, 0113466.

Research output: Contribution to journal › Article › peer-review

Open Access

File

115 Citations (Scopus)

204 Downloads (Pure)

Neutrophil elastase-mediated increase in airway temperature during inflammation

Schmidt, A., Belaaouaj, A., Bissinger, R., Koller, G., Malleret, L., D'Orazio, C., Facchinelli, M., Schulte-Hubbert, B., Molinaro, A., Holst, O., Hammermann, J., Schniederjans, M., Meyer, K. C., Damkiaer, S., Piacentini, G., Assael, B., Bruce, K., Häußler, S., LiPuma, J. J., Seelig, J., & 2 othersWorlitzsch, D. & Doring, G., Dec 2014, In: Journal Of Cystic Fibrosis. 13, 6, p. 623-631 9 p.

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Potentially Pathogenic Airway Bacteria and Neutrophilic Inflammation in Treatment Resistant Severe Asthma

Green, B. J., Wiriyachaiporn, S., Grainge, C., Rogers, G. B., Kehagia, V., Lau, L., Carroll, M. P., Bruce, K. D. & Howarth, P. H., 23 Jun 2014, In: PL o S One . 9, 6, 7 p., 100645.

Research output: Contribution to journal › Article › peer-review

Open Access

File

251 Citations (Scopus)

88 Downloads (Pure)

The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: An analysis from the randomised, double-blind, placebo-controlled BLESS trial

Rogers, G. B., Bruce, K. D., Martin, M. L., Burr, L. D. & Serisier, D. J., 1 Dec 2014, In: The Lancet Respiratory Medicine. 2, 12, p. 988-996 9 p.

Research output: Contribution to journal › Article › peer-review

152 Citations (Scopus)

Three clinically distinct chronic pediatric airway infections share a common core microbiota

Van Der Gast, C. J., Cuthbertson, L., Rogers, G. B., Pope, C., Marsh, R. L., Redding, G. J., Bruce, K. D., Chang, A. B. & Hoffman, L. R., 30 Sept 2014, In: Annals of the American Thoracic Society. 11, 7, p. 1039-1048 10 p.

Research output: Contribution to journal › Article › peer-review

83 Citations (Scopus)

Time between Collection and Storage Significantly Influences Bacterial Sequence Composition in Sputum Samples from Cystic Fibrosis Respiratory Infections

Cuthbertson, L., Rogers, G. B., Walker, A. W., Oliver, A., Hafiz, T., Hoffman, L. R., Carroll, M. P., Parkhill, J., Bruce, K. D. & van der Gast, C. J., Aug 2014, In: Journal of Clinical Microbiology. 52, 8, p. 3011-3016 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Citations (Scopus)

2013

A relationship between Pseudomonal growth behaviour and cystic fibrosis patient lung function identified in a metabolomic investigation

Kozlowska, J., Rivett, D., Vermeer, L., Carroll, M. P., Bruce, K., Mason, J. & Rogers, G., 1 Dec 2013, In: Metabolomics. 9, 6, p. 1262-1273 12 p., N/A.

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition

Rogers, G., van der Gast, C. J., Cuthbertson, L., Thomson, S. K., Bruce, K. D., Martin, M. L. & Serisier, D. J., Aug 2013, In: Thorax. 68, 8, p. 731-737

Research output: Contribution to journal › Article › peer-review

163 Citations (Scopus)

Comparison of the Distal Gut Microbiota from People and Animals in Africa

Ellis, R. J., Bruce, K. D., Jenkins, C., Stothard, J. R., Ajarova, L., Mugisha, L. & Viney, M. E., 23 Jan 2013, In: PL o S One . 8, 1, 11 p., 54783.

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Complexity, Temporal Stability, and Clinical Correlates of Airway Bacterial Community Composition in Primary Ciliary Dyskinesia

Rogers, G. B., Carroll, M. P., Zain, N. M. M., Bruce, K. D., Lock, K., Walker, W., Jones, G., Daniels, T. W. V. & Lucas, J. S., Dec 2013, In: Journal of Clinical Microbiology. 51, 12, p. 4029-4035 7 p., N/A.

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Evaluation of a Rapid Lateral Flow Immunoassay for Evaluation of Staphylococcus aureus Detection in Respiratory Samples

Wiriyachaiporn, S., Howarth, P., Bruce, K. & Dailey, L. A., Jan 2013, In: Diagnostic Microbiology and Infectious Disease. 75, 1, p. 28-36 9 p.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Impact of antibiotic treatment for pulmonary exacerbations on bacterial diversity in cystic fibrosis

Daniels, T. W. V., Rogers, G. B., Stressmann, F. A., van der Gast, C. J., Bruce, K. D., Jones, G. R., Connett, G. J., Legg, J. P. & Carroll, M. P., Jan 2013, In: Journal Of Cystic Fibrosis. 12, 1, p. 22-28 7 p.

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Reducing bias in bacterial community analysis of lower respiratory infections

Rogers, G. B., Cuthbertson, L., Hoffman, L. R., Wing, P. A., Pope, C., Hooftman, D. A. P., Lilley, A. K., Oliver, A., Carroll, M. P., Bruce, K. D. & van der Gast, C. J., Apr 2013, In: The ISME journal. 7, 4, p. 697-706 10 p.

Research output: Contribution to journal › Article › peer-review

76 Citations (Scopus)

Staphylococcus aureus Small-Colony Variants Are Independently Associated With Worse Lung Disease in Children With Cystic Fibrosis

Wolter, D. J., Emerson, J. C., McNamara, S., Buccat, A. M., Qin, X., Cochrane, E., Houston, L. S., Rogers, G. B., Marsh, P., Prehar, K., Pope, C. E., Blackledge, M., Deziel, E., Bruce, K. D., Ramsey, B. W., Gibson, R. L., Burns, J. L. & Hoffman, L. R., 1 Aug 2013, In: Clinical Infectious Diseases. 57, 3, p. 384-391 8 p.

Research output: Contribution to journal › Article › peer-review

146 Citations (Scopus)

The Cystic Fibrosis Airway Microbiome

Lynch, S. V. & Bruce, K. D., Mar 2013, In: Cold Spring Harbor perspectives in medicine. 3, 3, 7 p., 009738.

Research output: Contribution to journal › Article › peer-review

88 Citations (Scopus)

2012

A Quantitative Analysis of Ureaplasma urealyticum and Ureaplasma parvum Compared with Host Immune Response in Preterm Neonates at Risk of Developing Bronchopulmonary Dysplasia

Payne, M. S., Goss, K. C. W., Connett, G. J., Legg, J. P., Bruce, K. D. & Chalker, V., Mar 2012, In: Journal of Clinical Microbiology. 50, 3, p. 909 - 914 6 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Genomic Variation among Contemporary Pseudomonas aeruginosa Isolates from Chronically Infected Cystic Fibrosis Patients

Chung, J. C. S., Becq, J., Fraser, L., Schulz-Trieglaff, O., Bond, N. J., Foweraker, J., Bruce, K. D., Smith, G. P. & Welch, M., Sept 2012, In: Journal of Bacteriology. 194, 18, p. 4857-4866 10 p.

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Long-term cultivation-independent microbial diversity analysis demonstrates that bacterial communities infecting the adult cystic fibrosis lung show stability and resilience

Stressmann, F. A., Rogers, G. B., van der Gast, C. J., Marsh, P., Vermeer, L. S., Carroll, M. P., Hoffman, L., Daniels, T. W. V., Patel, N., Forbes, B. & Bruce, K. D., Oct 2012, In: Thorax. 67, 10, p. 867-873 7 p.

Research output: Contribution to journal › Article › peer-review

127 Citations (Scopus)

Kenneth Bruce

Research output

Search results