Kinya Otsu
  • 12756

Personal profile

Research interests (short)

Identification of therapeutic targets for heart failure; cardiomyocyte death; mitochondria

Research interests

Heart failure can be defined as “cardiomyocyte-deficiency syndrome”. Three types of cell death, namely apoptosis, necrosis and autophagic death, have been reported. Various types of cardiomyocyte death may play an important role in the development and progression of heart failure. Our research aims to (a) characterize various types of cardiomyocyte death and test the above hypothesis, (b) elucidate underlying mechanisms that are involved (c) examine whether the regulation of cell death may be a novel therapeutic approach to treat patients with heart failure. Our research involves the application of integrated in vivo physiological studies, molecular, cell biological, imaging and signalling studies using gene-targeting mice to investigate the role of cardiomyocyte death in development of heart failure.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being


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