Konstantinos Theofilatos

2023

Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

Romeo, S., Secco, I., Schneider, E., Reumiller, C. M., Santos, C. X. C., Zoccarato, A., Musale, V., Pooni, A., Yin, X., Theofilatos, K., Cellone Trevelin, S., Zeng, L., Mann, G., Pathak, V., Harkin, K., Stitt, A. W., Medina, R. J., Margariti, A., Mayr, M., Shah, A., & 2 othersGiacca, M. & Zampetaki, A., 30 Aug 2023, (Accepted/In press) In: Nature Communications. 19 p.

Research output: Contribution to journal › Article › peer-review

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2 Downloads (Pure)

Optimisation Models for Pathway Activity Inference in Cancer

Chen, Y., Liu, S., Papageorgiou, L. G., Theofilatos, K. & Tsoka, S., 15 Mar 2023, In: Cancers. 15, 6, 1787.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Editorial: Non-coding RNAs in heart failure

Booz, G. W. & Theofilatos, K. A., 24 Aug 2022, In: Frontiers in Cardiovascular Medicine. 9, 1016139.

Research output: Contribution to journal › Editorial › peer-review

Open Access

Precision Medicine Approach for Cardiometabolic Risk Factors in Therapeutic Apheresis

Yin, X., Takov, K., Straube, R., Voit-Bak, K., Graessler, J., Julius, U., Tselmin, S., Rodionov, R., Barbir, M., Walls, M., Theofilatos, K., Mayr, M. & Bornstein, S. R., 12 Apr 2022, (E-pub ahead of print) In: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 54, 4, p. 238-249 12 p.

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Reduced secretion of neuronal growth regulator 1 contributes to impaired adipose-neuronal crosstalk in obesity

Duregotti, E., Reumiller, C. M., Mayr, U., Hasman, M., Schmidt, L. E., Burnap, S. A., Theofilatos, K., Barallobre-Barreiro, J., Beran, A., Grandoch, M., Viviano, A., Jahangiri, M. & Mayr, M., Dec 2022, In: Nature Communications. 13, 1, 7269.

Research output: Contribution to journal › Article › peer-review

Open Access

Serial measurements of protein and microRNA biomarkers to specify myocardial infarction subtypes

Schulte, C., Singh, B., Theofilatos, K., Sörensen, N. A., Lehmacher, J., Hartikainen, T., Haller, P. M., Westermann, D., Zeller, T., Blankenberg, S., Neumann, J. T. & Mayr, M., Sept 2022, In: Journal of molecular and cellular cardiology plus. 1, p. None

Research output: Contribution to journal › Article › peer-review

2021

Association of cardiometabolic microRNAs with COVID-19 severity and mortality

Gutmann, C., Khamina, K., Theofilatos, K., Diendorfer, A. B., Burnap, S. A., Nabeebaccus, A., Fish, M., McPhail, M. J. W., O'Gallagher, K., Schmidt, L. E., Cassel, C., Auzinger, G., Napoli, S., Mujib, S. F., Trovato, F., Sanderson, B., Merrick, B., Roy, R., Edgeworth, J. D., Shah, A. M., & 6 othersHayday, A. C., Traby, L., Hackl, M., Eichinger, S., Shankar-Hari, M. & Mayr, M., 10 Nov 2021, (E-pub ahead of print) In: Cardiovascular Research.

Research output: Contribution to journal › Article › peer-review

Open Access

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32 Citations (Scopus)

83 Downloads (Pure)

Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling

Barallobre-Barreiro, J., Radovits, T., Fava, M., Mayr, U., Lin, W. Y., Ermolaeva, E., Martínez-López, D., Lindberg, E. L., Duregotti, E., Daróczi, L., Hasman, M., Schmidt, L. E., Singh, B., Lu, R., Baig, F., Siedlar, A. M., Cuello, F., Catibog, N., Theofilatos, K., Shah, A. M., & 5 othersCrespo-Leiro, M. G., Doménech, N., Hübner, N., Merkely, B. & Mayr, M., 21 Dec 2021, In: Circulation. 144, 25, p. 2021-2034 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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9 Citations (Scopus)

77 Downloads (Pure)

HDL COMPARTMENTALISATION REGULATES PCSK9 ACTIVITY

Burnap, S. A., Sattler, K., Pechlaner, R., Theofilatos, K., Takov, K., Heusch, G., Tsimikas, S., Fernandez-Hernando, C., Berry, S. E., Hall, W., Notdurfter, M., Rungger, G., Willeit, J., Kiechl, S., Levkau, B. & Mayr, M., Aug 2021, In: Atherosclerosis. 331, p. E39-E39

Research output: Contribution to journal › Meeting Abstract › peer-review

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

Cuello, F., Knaust, A. E., Saleem, U., Loos, M., Raabe, J., Mosqueira, D., Laufer, S., Schweizer, M., van der Kraak, P., Flenner, F., Ulmer, B. M., Braren, I., Yin, X., Theofilatos, K., Ruiz-Orera, J., Patone, G., Klampe, B., Schulze, T., Piasecki, A., Pinto, Y., & 7 othersVink, A., Hübner, N., Harding, S., Mayr, M., Denning, C., Eschenhagen, T. & Hansen, A., 7 Jun 2021, In: EMBO Molecular Medicine. 13, 6, e13074.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Citations (Scopus)

Neutrophil Derived Protein S100A8/A9 Alters the Platelet Proteome in Acute Myocardial Infarction and Is Associated with Changes in Platelet Reactivity

Joshi, A., Schmidt, L., Burnap, S., Lu, R., Chan, M. V., Armstrong, P. C., Baig, F., Gutmann, C., Willeit, P., Santer, P., Barwari, T., Theofilatos, K., Kiechl, S., Willeit, J., Warner, T. D., Mathur, A. & Mayr, M., 1 Nov 2021, (Accepted/In press) In: ATVB.

Research output: Contribution to journal › Article › peer-review

Open Access

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PCSK9 Activity Is Potentiated Through HDL Binding

Burnap, S. A., Sattler, K., Pechlaner, R., Duregotti, E., Lu, R., Theofilatos, K., Takov, K., Heusch, G., Tsimikas, S., Fernandez-Hernando, C., Berry, S. E., Hall, W. L., Notdurfter, M., Rungger, G., Paulweber, B., Willeit, J., Kiechl, S., Levkau, B. & Mayr, M., 12 Nov 2021, In: Circulation Research. 129, 11, p. 1039-1053 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy: Development of PLN-R14del-Related Cardiomyopathy

Eijgenraam, T. R., Boogerd, C. J., Stege, N. M., Oliveira Nunes Teixeira, V., Dokter, M. M., Schmidt, L. E., Yin, X., Theofilatos, K., Mayr, M., van der Meer, P., van Rooij, E., van der Velden, J., Silljé, H. H. W. & de Boer, R. A., 1 Nov 2021, In: Circulation-Heart Failure. 14, 11, p. e008532

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

Gutmann, C., Takov, K., Burnap, S. A., Singh, B., Ali, H., Theofilatos, K., Reed, E., Hasman, M., Nabeebaccus, A., Fish, M., McPhail, M. J., O'Gallagher, K., Schmidt, L. E., Cassel, C., Rienks, M., Yin, X., Auzinger, G., Napoli, S., Mujib, S. F., Trovato, F., & 17 othersSanderson, B., Merrick, B., Niazi, U., Saqi, M., Dimitrakopoulou, K., Fernández-Leiro, R., Braun, S., Kronstein-Wiedemann, R., Doores, K. J., Edgeworth, J. D., Shah, A. M., Bornstein, S. R., Tonn, T., Hayday, A. C., Giacca, M., Shankar-Hari, M. & Mayr, M., Dec 2021, In: Nature Communications. 12, 1, 3406.

Research output: Contribution to journal › Article › peer-review

Open Access

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81 Citations (Scopus)

136 Downloads (Pure)

2020

Identification of Important Biological Pathways for Ischemic Stroke Prediction through a Mathematical Programming Optimisation Model-DIGS

Chen, Y., Theofilatos, K., Papageorgiou, L. G. & Tsoka, S., 22 May 2020, Proceedings of the 2020 12th International Conference on Bioinformatics and Biomedical Technology, ICBBT 2020. Association for Computing Machinery, p. 25-31 7 p. (ACM International Conference Proceeding Series).

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

1 Citation (Scopus)

Metabolic recovery after weight loss surgery is reflected in serum microRNAs

Sangiao-Alvarellos, S., Theofilatos, K., Barwari, T., Gutmann, C., Takov, K., Singh, B., Juiz-Valiña, P., Varela-Rodríguez, B. M., Outeiriño-Blanco, E., Duregotti, E., Zampetaki, A., Lunger, L., Ebenbichler, C., Tilg, H., García-Brao, M. J., Willeit, P., Mena, E., Kiechl, S., Cordido, F. & Mayr, M., 28 Oct 2020, In: BMJ Open Diabetes Research & Care. 8, 2, e001441.

Research output: Contribution to journal › Article › peer-review

Open Access