Research output per year
Research output per year
- 22 results
Search results
-
2024
A Versatile Virus-Mimetic Engineering Approach for Concurrent Protein Nanocage Surface-Functionalization and Cargo Encapsulation
Sheng, Y., Chen, Z., Cherrier, M. V., Martin, L., Bui, T. T. T., Li, W., Lynham, S., Nicolet, Y. & Ebrahimi, K. H., 1 Aug 2024, In: Small. 20, 31, 2310913.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
2022
Density dependent regulation of inflammatory responses in macrophages
Vaughan-Jackson, A., Stodolak, S., Ebrahimi, K. H., Johnson, E., Reardon, P. K., Dupont, M., Zhang, S., McCullagh, J. S. O. & James, W. S., 16 Dec 2022, In: Frontiers in Immunology. 13, 895488.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Iron–sulfur clusters as inhibitors and catalysts of viral replication
Honarmand Ebrahimi, K., Ciofi-Baffoni, S., Hagedoorn, P. L., Nicolet, Y., Le Brun, N. E., Hagen, W. R. & Armstrong, F. A., Mar 2022, In: Nature Chemistry. 14, 3, p. 253-266 14 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Citations (Scopus) -
Radical-SAM dependent nucleotide dehydratase (SAND), rectification of the names of an ancient iron-sulfur enzyme using NC-IUBMB recommendations
Ji, Y., Wei, L., Da, A., Stark, H., Hagedoorn, P. L., Ciofi-Baffoni, S., Cowley, S. A., Louro, R. O., Todorovic, S., Mroginski, M. A., Nicolet, Y., Roessler, M. M., Le Brun, N. E., Piccioli, M., James, W. S., Hagen, W. R. & Ebrahimi, K. H., 21 Oct 2022, In: Frontiers in Molecular Biosciences. 9, 1032220.Research output: Contribution to journal › Comment/debate › peer-review
Open Access5 Citations (Scopus) -
Randomised controlled trial of intravenous nafamostat mesylate in COVID pneumonitis: Phase 1b/2a experimental study to investigate safety, Pharmacokinetics and Pharmacodynamics
Quinn, T. M., Gaughan, E. E., Bruce, A., Antonelli, J., O'Connor, R., Li, F., McNamara, S., Koch, O., MacKintosh, C., Dockrell, D., Walsh, T., Blyth, K. G., Church, C., Schwarze, J., Boz, C., Valanciute, A., Burgess, M., Emanuel, P., Mills, B. & Rinaldi, G. & 29 others, , Feb 2022, In: EBioMedicine. 76, 103856.Research output: Contribution to journal › Article › peer-review
Open Access41 Citations (Scopus) -
2021
A lipidomic view of SARS-CoV-2
H. Ebrahimi, K. & McCullagh, J. S., 27 Aug 2021, In: Bioscience Reports. 41, 8, BSR20210953.Research output: Contribution to journal › Editorial › peer-review
Open Access10 Citations (Scopus) -
Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium
Vaughan-Jackson, A., Stodolak, S., H. Ebrahimi, K., Browne, C., K. Reardon, P., Gilbert-Jaramillo, J., A. Cowley, S. & James, W., 13 Jul 2021, In: Stem Cell Reports. 16, 7, p. 1735-1748 14 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Citations (Scopus) -
Ferritin as a Platform for Creating Antiviral Mosaic Nanocages: Prospects for Treating COVID-19
H. Ebrahimi, K., 16 Apr 2021, In: Chembiochem : a European journal of chemical biology. 22, 8, p. 1371-1378 8 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access4 Citations (Scopus) -
Hidden in Plain Sight: Natural Products of Commensal Microbiota as an Environmental Selection Pressure for the Rise of New Variants of SARS‐CoV‐2
Dragelj, J., Mroginski, M. A. & H. Ebrahimi, K., 13 Oct 2021, In: Chembiochem : a European journal of chemical biology. 22, 20, p. 2946-2950 5 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
Interferon-stimulated gene products as regulators of central carbon metabolism
H. Ebrahimi, K., Gilbert-Jaramillo, J., S. James, W. & S. O. McCullagh, J., Jun 2021, In: The FEBS journal. 288, 12, p. 3715-3726 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal
Rack, J. G. M., Liu, Q., Zorzini, V., Voorneveld, J., Ariza, A., H. Ebrahimi, K., M. Reber, J., C. Krassnig, S., Ahel, D., van der Marel, G. A., Mangerich, A., S. O. McCullagh, J., V. Filippov, D. & Ahel, I., 2021, In: Nature Communications. 12, 1, 4581.Research output: Contribution to journal › Article › peer-review
Open Access43 Citations (Scopus) -
2020
ddhCTP produced by the radical-SAM activity of RSAD2 (viperin) inhibits the NAD+ -dependent activity of enzymes to modulate metabolism
H. Ebrahimi, K., Vowles, J., Browne, C., McCullagh, J. S. & S. James, W., May 2020, In: FEBS Letters. 594, 10, p. 1631-1644 14 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Citations (Scopus) -
Mechanism of Diol Dehydration by a Promiscuous Radical-SAM Enzyme Homologue of the Antiviral Enzyme Viperin (RSAD2)
H. Ebrahimi, K., S. Rowbotham, J., McCullagh, J. S. & James, W., 2 Jun 2020, In: Chembiochem : a European journal of chemical biology. 21, 11, p. 1605-1612 8 p.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
Nanofactories for Controlled Synthesis and Delivery of Nucleoside Analogue Therapeutics
H. Ebrahimi, K., 16 Nov 2020, In: Chembiochem : a European journal of chemical biology. 21, 22, p. 3186-3188 3 p.Research output: Contribution to journal › Comment/debate › peer-review
1 Citation (Scopus) -
SARS-CoV-2 spike glycoprotein-binding proteins expressed by upper respiratory tract bacteria may prevent severe viral infection
H. Ebrahimi, K., Jun 2020, In: FEBS Letters. 594, 11, p. 1651-1660 10 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
Viperin, through its radical‐SAM activity, depletes cellular nucleotide pools and interferes with mitochondrial metabolism to inhibit viral replication
H. Ebrahimi, K., Howie, D., S. Rowbotham, J., McCullagh, J. S., A. Armstrong, F. & James, W., 25 Mar 2020, In: FEBS Letters. 594, 10, p. 1624-1630Research output: Contribution to journal › Article › peer-review
Open Access26 Citations (Scopus) -
2018
A unifying view of the broad-spectrum antiviral activity of RSAD2 (viperin) based on its radical-SAM chemistry
H. Ebrahimi, K., 2018, In: Metallomics. 10, 4, p. 539-552Research output: Contribution to journal › Review article › peer-review
34 Citations (Scopus) -
Evidence for the synthesis of an unusual high spin (S= 7/2)[Cu–3Fe–4S] cluster in the radical-SAM enzyme RSAD2 (viperin)
H. Ebrahimi, K., Silveira, C. & Todorovic, S., 2018, In: Chemical Communications. 54, p. 8614-8617Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Fast and accurate enzyme activity measurements using a chip-based microfluidic calorimeter
M. C. H. van Schie, M., H. Ebrahimi, K., Hagen, W. & Hagedoorn, P.-L., 1 Mar 2018, In: Analytical Biochemistry. 544, p. 57-63Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
2017
The radical‐SAM enzyme Viperin catalyzes reductive addition of a 5′‐deoxyadenosyl radical to UDP‐glucose in vitro
H. Ebrahimi, K., B. Carr, S., McCullagh, J. S., Wickens, J., H. Rees, N., Cantley, J. & A. Armstrong, F., 28 Jul 2017, In: FEBS Letters. 591, 16, p. 2394-2405Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
2015
Unity in the Biochemistry of the Iron-Storage Proteins Ferritin and Bacterioferritin
H. Ebrahimi, K., Hagedoorn, P.-L. & Hagen, W., 2015, In: Chemical Reviews. 115, 1, p. 295-326Research output: Contribution to journal › Review article › peer-review
224 Citations (Scopus) -
2012
The catalytic center of ferritin regulates iron storage via Fe (II)-Fe (III) displacement
H. Ebrahimi, K., Bill, E., Hagedoorn, P.-L. & Technology, D. U., 2012, In: Nature Chemical Biology. 8, p. 941-948Research output: Contribution to journal › Article › peer-review
108 Citations (Scopus)