King's College London

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Dr Kuang Lin

  1. A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

    Ranlund, S. , Calafato, S. , Thygesen, J. H. , Lin, K. , Cahn, W. , Crespo-Facorro, B. , de Zwarte, S. M. C. , Díez, Á. , Di Forti, M. , Iyegbe, C. , Jablensky, A. , Jones, R. , Hall, M. H. , Kahn, R. , Kalaydjieva, L. , Kravariti, E. , Mcdonald, C. , Mcintosh, A. M. , Mcquillin, A. , Picchioni, M. & 13 others Prata, D. P., Rujescu, D., Schulze, K., Shaikh, M., Toulopoulou, T., van Haren, N., van Os, J., Vassos, E., Walshe, M., Lewis, C., Murray, R. M., Powell, J. & Bramon, E. 29 Aug 2017 In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics.

    Research output: Contribution to journalArticle

  2. Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

    van Rheenen, W. , Shatunov, A. , Dekker, A. M. , McLaughlin, R. L. , Diekstra, F. P. , Pulit, S. L. , van der Spek, R. A. A. , Võsa, U. , de Jong, S. , Robinson, M. R. , Yang, J. , Fogh, I. , van Doormaal, P. T. , Tazelaar, G. H. P. , Koppers, M. , Blokhuis, A. M. , Sproviero, W. , Jones, A. R. , Kenna, K. P. , van Eijk, K. R. & 158 others Harschnitz, O., Schellevis, R. D., Brands, W. J., Medic, J., Menelaou, A., Vajda, A., Ticozzi, N., Lin, K., Rogelj, B., Vrabec, K., Ravnik-Glavač, M., Koritnik, B., Zidar, J., Leonardis, L., Grošelj, L. D., Millecamps, S., Salachas, F., Meininger, V., de Carvalho, M., Pinto, S., Mora, J. S., Rojas-García, R., Polak, M., Chandran, S., Colville, S., Swingler, R., Morrison, K. E., Shaw, P. J., Hardy, J., Orrell, R. W., Pittman, A., Sidle, K., Fratta, P., Malaspina, A., Topp, S., Petri, S., Abdulla, S., Drepper, C., Sendtner, M., Meyer, T., Ophoff, R. A., Staats, K. A., Wiedau-Pazos, M., Lomen-Hoerth, C., Van Deerlin, V. M., Trojanowski, J. Q., Elman, L., McCluskey, L., Basak, A. N., Tunca, C., Hamzeiy, H., Parman, Y., Meitinger, T., Lichtner, P., Radivojkov-Blagojevic, M., Andres, C. R., Maurel, C., Bensimon, G., Landwehrmeyer, B., Brice, A., Payan, C. A. M., Saker-Delye, S., Dürr, A., Wood, N. W., Tittmann, L., Lieb, W., Franke, A., Rietschel, M., Cichon, S., Nöthen, M. M., Amouyel, P., Tzourio, C., Dartigues, J-F., Uitterlinden, A. G., Rivadeneira, F., Estrada, K., Hofman, A., Curtis, C., Blauw, H. M., van der Kooi, A. J., de Visser, M., Goris, A., Weber, M., Shaw, C. E., Smith, B. N., Pansarasa, O., Cereda, C., Del Bo, R., Comi, G. P., D'Alfonso, S., Bertolin, C., Sorarù, G., Mazzini, L., Pensato, V., Gellera, C., Tiloca, C., Ratti, A., Calvo, A., Moglia, C., Brunetti, M., Arcuti, S., Capozzo, R., Zecca, C., Lunetta, C., Penco, S., Riva, N., Padovani, A., Filosto, M., Muller, B., Stuit, R. J., Blair, I., Zhang, K., McCann, E. P., Fifita, J. A., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Grosskreutz, J., Witte, O. W., Ringer, T., Prell, T., Stubendorff, B., Kurth, I., Hübner, C. A., Leigh, P. N., Casale, F., Chio, A., Beghi, E., Pupillo, E., Tortelli, R., Logroscino, G., Powell, J., Ludolph, A. C., Weishaupt, J. H., Robberecht, W., Van Damme, P., Franke, L., Pers, T. H., Brown, R. H., Glass, J. D., Landers, J. E., Hardiman, O., Andersen, P. M., Corcia, P., Vourc'h, P., Silani, V., Wray, N. R., Visscher, P. M., de Bakker, P. I. W., van Es, M. A., Pasterkamp, R. J., Lewis, C. M., Breen, G., Al-Chalabi, A., van den Berg, L. H., Veldink, J. H. & PARALS Registry 25 Jul 2016 In : Nature Genetics.

    Research output: Contribution to journalArticle

  3. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

    Fogh, I. , Lin, K. , Tiloca, C. , Rooney, J. , Gellera, C. , Diekstra, F. P. , Ratti, A. , Shatunov, A. , Van Es, M. A. , Proitsi, P. , Jones, A. , Sproviero, W. , Chiò, A. , McLaughlin, R. L. , Sorarù, G. , Corrado, L. , Stahl, D. , Del Bo, R. , Cereda, C. , Castellotti, B. & 29 others Glass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J. 1 Jul 2016 In : JAMA Neurology. 73, 7, p. 812-820 9 p.

    Research output: Contribution to journalArticle

  4. Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

    Proitsi, P. , Lupton, M. K. , Velayudhan, L. , Hunter, G. , Newhouse, S. , Lin, K. , Fogh, I. , Tsolaki, M. , Daniilidou, M. , Pritchard, M. , Craig, D. , Todd, S. , Johnston, J. A. , McGuinness, B. , Kloszewska, I. , Soininen, H. , Mecocci, P. , Vellas, B. , Passmore, P. A. , Sims, R. & 7 others Williams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S., Powell, J. F. & Alzheimer's Disease Neuroimaging Initiative Dec 2014 In : Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p., 2883

    Research output: Contribution to journalArticle

  5. A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis

    Fogh, I. , Ratti, A. , Gellera, C. , Lin, K. , Tiloca, C. , Moskvina, V. , Corrado, L. , Sorarù, G. , Cereda, C. , Corti, S. , Gentilini, D. , Calini, D. , Castellotti, B. , Mazzini, L. , Querin, G. , Gagliardi, S. , Del Bo, R. , Conforti, F. L. , Siciliano, G. , Inghilleri, M. & 46 others Saccà, F., Bongioanni, P., Penco, S., Corbo, M., Sorbi, S., Filosto, M., Ferlini, A., Di Blasio, A. M., Signorini, S., Shatunov, A., Jones, A., Shaw, P. J., Morrison, K. E., Farmer, A. E., Van Damme, P., Robberecht, W., Chiò, A., Traynor, B. J., Sendtner, M., Melki, J., Meininger, V., Hardiman, O., Andersen, P. M., Leigh, N. P., Glass, J. D., Overste, D., Diekstra, F. P., Veldink, J. H., van Es, M. A., Shaw, C. E., Weale, M. E., Lewis, C. M., Williams, J., Brown, R. H., Landers, J. E., Ticozzi, N., Ceroni, M., Pegoraro, E., Comi, G. P., D'Alfonso, S., van den Berg, L. H., Taroni, F., Al-Chalabi, A., Powell, J., Silani, V. & the SLAGEN Consortium Collaborators 15 Apr 2014 In : Human Molecular Genetics. 23, 8, p. 2220-2231 12 p., N/A

    Research output: Contribution to journalArticle

  6. A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation

    Bramon, E. , Pirinen, M. , Strange, A. , Lin, K. , Freeman, C. , Bellenguez, C. , Su, Z. , Band, G. , Pearson, R. , Vukcevic, D. , Langford, C. , Deloukas, P. , Hunt, S. , Gray, E. , Dronov, S. , Potter, S. C. , Tashakkori-Ghanbaria, A. , Edkins, S. , Bumpstead, S. J. , Arranz, M. J. & 63 others Bakker, S., Bender, S., Bruggeman, R., Cahn, W., Chandler, D., Collier, D. A., Crespo-Facorro, B., Dazzan, P., de Haan, L., Di Forti, M., Dragović, M., Giegling, I., Hall, J., Iyegbe, C., Jablensky, A., Kahn, R. S., Kalaydjieva, L., Kravariti, E., Lawrie, S., Linszen, D. H., Mata, I., McDonald, C., McIntosh, A., Myin-Germeys, I., Ophoff, R. A., Pariante, C. M., Paunio, T., Picchioni, M., Ripke, S., Rujescu, D., Sauer, H., Shaikh, M., Sussmann, J., Suvisaari, J., Tosato, S., Toulopoulou, T., Van Os, J., Walshe, M., Weisbrod, M., Whalley, H., Wiersma, D., Blackwell, J. M., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J. A. Z., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Wood, N. W., Barroso, I., Peltonen, L., Lewis, C. M., Murray, R. M., Donnelly, P., Powell, J., Spencer, C. C. A. & Psychosis Endophenotypes International Consortium 1 Mar 2014 In : Biological Psychiatry. 75, 5, p. 386-397 12 p.

    Research output: Contribution to journalArticle

  7. Common variant at 16p11.2 conferring risk of psychosis

    Steinberg, S. , De Jong, S. , Mattheisen, M. , Costas, J. , Demontis, D. , Jamain, S. , Pietilainen, O. P. H. , Lin, K. , Papiol, S. , Huttenlocher, J. , Sigurdsson, E. , Vassos, E. , Giegling, I. , Breuer, R. , Fraser, G. , Walker, N. , Melle, I. , Djurovic, S. , Agartz, I. , Tuulio-henriksson, A. & 110 others Suvisaari, J., Lonnqvist, J., Paunio, T., Olsen, L., Hansen, T., Ingason, A., Pirinen, M., Strengman, E., Hougaard, D. M., Orntoft, T., Didriksen, M., Hollegaard, M. V., Nordentoft, M., Abramova, L., Kaleda, V., Arrojo, M., Sanju??n, J., Arango, C., Etain, B., Bellivier, F., M??ary, A., Sch??rhoff, F., Szoke, A., Ribolsi, M., Magni, V., Siracusano, A., Sperling, S., Rossner, M., Christiansen, C., Kiemeney, L. A., Franke, B., Van Den Berg, L. H., Veldink, J., Curran, S., Bolton, P., Poot, M., Staal, W., Rehnstrom, K., Kilpinen, H., Freitag, C. M., Meyer, J., Magnusson, P., Saemundsen, E., Martsenkovsky, I., Bikshaieva, I., Martsenkovska, I., Vashchenko, O., Raleva, M., Paketchieva, K., Stefanovski, B., Durmishi, N., Pejovic Milovancevic, M., Lecic Tosevski, D., Silagadze, T., Naneishvili, N., Mikeladze, N., Surguladze, S., Vincent, J. B., Farmer, A., Mitchell, P. B., Wright, A., Schofield, P. R., Fullerton, J. M., Montgomery, G. W., Martin, N. G., Rubino, I. A., Van Winkel, R., Kenis, G., De Hert, M., R??thelyi, J. M., Bitter, I., Terenius, L., J??nsson, E. G., Bakker, S., Van Os, J., Jablensky, A., Leboyer, M., Bramon, E., Powell, J., Murray, R., Corvin, A., Gill, M., Morris, D., O'Neill, F. A., Kendler, K., Riley, B., Wellcome Trust Case Control Consortium 2, Craddock, N., Owen, M. J., O'donovan, M. C., Thorsteinsdottir, U., Kong, A., Ehrenreich, H., Carracedo, A., Golimbet, V., Andreassen, O. A., B??rglum, A. D., Mors, O., Mortensen, P. B., Werge, T., Ophoff, R. A., N??then, M. M., Rietschel, M., Cichon, S., Ruggeri, M., Tosato, S., Palotie, A., St Clair, D., Rujescu, D. & Collier, D. A. Jan 2014 In : Molecular Psychiatry. 19, 1, p. 108-114 7 p.

    Research output: Contribution to journalArticle

  8. The role of ABCA1 gene sequence variants on risk of Alzheimer's disease

    Lupton, M. K., Proitsi, P., Lin, K., Hamilton, G., Daniilidou, M., Tsolaki, M. & Powell, J. F. 2014 In : Journal of Alzheimer's disease : JAD. 38, 4, p. 897-906 10 p.

    Research output: Contribution to journalArticle

  9. Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Ripke, S. , O'dushlaine, C. , Chambert, K. , Moran, J. L. , K??hler, A. K. , Akterin, S. , Bergen, S. E. , Collins, A. L. , Crowley, J. J. , Fromer, M. , Kim, Y. , Lee, S. H. , Magnusson, P. K. E. , Sanchez, N. , Stahl, E. A. , Williams, S. , Wray, N. R. , Xia, K. , Bettella, F. , Borglum, A. D. & 47 others Bulik-sullivan, B. K., Cormican, P., Craddock, N., De Leeuw, C., Durmishi, N., Gill, M., Golimbet, V., Hamshere, M. L., Holmans, P., Hougaard, D. M., Kendler, K. S., Lin, K., Morris, D. W., Mors, O., Mortensen, P. B., Neale, B. M., O'neill, F. A., Owen, M. J., Milovancevic, M. P., Posthuma, D., Powell, J., Richards, A. L., Riley, B. P., Ruderfer, D., Rujescu, D., Sigurdsson, E., Silagadze, T., Smit, A. B., Stefansson, H., Steinberg, S., Suvisaari, J., Tosato, S., Verhage, M., Walters, J. T., Multicenter Genetic Studies of Schizophrenia Consortium, Psychosis Endophenotypes International Consortium, Wellcome Trust Case Consortium 2, Bramon, E., Corvin, A. P., O'donovan, M. C., Stefansson, K., Scolnick, E., Purcell, S., Mccarroll, S. A., Sklar, P., Hultman, C. M. & Sullivan, P. F. Oct 2013 In : Nature Genetics. 45, 10, p. 1150-1159 10 p.

    Research output: Contribution to journalArticle

  10. C9ORF72 repeat expansion in a large Italian ALS cohort: evidence of a founder effect

    Ratti, A. , Corrado, L. , Castellotti, B. , Del Bo, R. , Fogh, I. , Cereda, C. , Tiloca, C. , D'Ascenzo, C. , Bagarotti, A. , Pensato, V. , Ranieri, M. , Gagliardi, S. , Calini, D. , Mazzini, L. , Taroni, F. , Corti, S. , Ceroni, M. , Oggioni, G. D. , Lin, K. , Powell, J. F. & 7 others Soraru, G., Ticozzi, N., Comi, G. P., D'Alfonso, S., Gellera, C., Silani, V. & SLAGEN Consortium Oct 2012 In : Neurobiology of Aging. 33, 10, p. - 8 p., 2528.e7

    Research output: Contribution to journalArticle

  11. Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris

    Tsang, S. M., Brown, L., Lin, K., Liu, L., Piper, K., O'Toole, E. A., Grose, R., Hart, I. R., Garrod, D. R., Fortune, F. & Wan, H. May 2012 In : Journal of Pathology. 227, 1, p. 81 - 93 13 p.

    Research output: Contribution to journalArticle

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