Personal profile
Research interests
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Research output
- 13 Article
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ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations
Stoica, R., Paillusson, S., Gomez-Suaga, P., Mitchell, J. C., Lau, D. H. W., Gray, E. H., Sancho, R. M., Vizcay-Barrena, G., De Vos, K. J., Shaw, C., Hanger, D. P., Noble, W. & Miller, C. C. J., 1 Sept 2016, In: EMBO Reports. 17, 9, p. 1326-1342 e201541726.Research output: Contribution to journal › Article › peer-review
Open AccessFile232 Citations (Scopus)299 Downloads (Pure) -
Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons
Rodríguez-Martín, T., Pooler, A. M., Lau, D. H. W., Mórotz, G. M., De Vos, K. J., Gilley, J., Coleman, M. P. & Hanger, D. P., 1 Jan 2016, In: Neurobiology of disease. 85, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile59 Citations (Scopus)279 Downloads (Pure) -
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
Morotz, G. M., De Vos, K. J., Vagnoni, A., Ackerley, S., Shaw, C. E. & Miller, C. C. J., May 2012, In: Human Molecular Genetics. 21, 9, p. 1979 - 1988 10 p., dds011.Research output: Contribution to journal › Article › peer-review
Open AccessFile122 Citations (Scopus)194 Downloads (Pure) -
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
Mórotz, G. M., De Vos, K. J., Vagnoni, A., Ackerley, S., Shaw, C. E. & Miller, C. C. J., 1 May 2012, In: Human Molecular Genetics. 21, 9, p. 1979-88 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo
Manser, C., Guillot, F., Vagnoni, A., Davies, J., Lau, K.-F., McLoughlin, D. M., De Vos, K. J. & Miller, C. C. J., 31 May 2012, In: Oncogene. 31, 22, p. 2773-82 10 p.Research output: Contribution to journal › Article › peer-review
Projects
- 6 Finished
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Defective axonal transport and impaired Ca2+handling in amyotrophic lateral sclerosis caused by mutant SOD1.
De Vos, K. (Primary Investigator)
1/10/2010 → 30/09/2013
Project: Research
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Role of axonal transport in Parkinson's disease
De Vos, K. (Co-Investigator)
1/02/2009 → 31/01/2011
Project: Research
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The X//a adaptor protein, KIF17 & dendric transport and processing of the amyloid precursor protein
De Vos, K. (Co-Investigator), Manser, C. (Co-Investigator) & Miller, C. (Co-Investigator)
1/02/2009 → 31/01/2012
Project: Research
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Role of axonal transport in Parkinson's disease
De Vos, K. (Co-Investigator)
2/07/2007 → 1/07/2012
Project: Research
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Analysis of the role of axonal transport of mitochondria and mitochondrial function in Alzheimer's disease
De Vos, K. (Co-Investigator) & Miller, C. (Co-Investigator)
1/01/2007 → 31/12/2011
Project: Research