King's College London

Research portal

Dr Laura Bertolaccini

  1. Development of New International Antiphospholipid Syndrome Classification Criteria Phase I/II Report: Generation and Reduction of Candidate Criteria

    New APS Classification Criteria Collaborators, Oct 2021, In: Arthritis care & research.

    Research output: Contribution to journalArticlepeer-review

  2. Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION): 10-Year Update

    APS ACTION Executive Committee, Jun 2021, In: Current Rheumatology Reports. 23, 6, 45.

    Research output: Contribution to journalReview articlepeer-review

  3. Identifying phenotypes of patients with antiphospholipid antibodies: results from a cluster analysis in a large cohort of patients

    Sciascia, S., Radin, M., Cecchi, I., Bertolaccini, M. L., Bertero, M. T., Rubini, E., Vaccarino, A., Bazzan, M., Giachino, O., Baldovino, S., Rossi, D., Mengozzi, G. & Roccatello, D., 2 Mar 2021, In: Rheumatology (Oxford, England). 60, 3, p. 1106-1113 8 p.

    Research output: Contribution to journalReview articlepeer-review

  4. Antiphospholipid Antibody Profile Stability Over Time: Prospective Results From the APS ACTION Clinical Database and Repository

    APS ACTION+, 1 Sep 2020, (E-pub ahead of print) In: Journal of Rheumatology.

    Research output: Contribution to journalArticlepeer-review

  5. Cluster analysis for the identification of clinical phenotypes among antiphospholipid antibody-positive patients from the APS ACTION Registry

    APS ACTION Investigators, 23 Jul 2020, (E-pub ahead of print) In: Lupus. 961203320940776.

    Research output: Contribution to journalArticlepeer-review

  6. Antiphosphatidylserine/Prothrombin Antibodies: An Update on Their Association with Clinical Manifestations of Antiphospholipid Syndrome

    Radin, M., Foddai, S. G., Cecchi, I., Rubini, E., Schreiber, K., Roccatello, D., Bertolaccini, M. L. & Sciascia, S., 1 Apr 2020, In: Thrombosis and Haemostasis. 120, 4, p. 592-598 7 p.

    Research output: Contribution to journalArticlepeer-review

  7. The adjusted global antiphospholipid syndrome score (aGAPSS)and the risk of recurrent thrombosis: Results from the APS ACTION cohort

    APS ACTION, 1 Dec 2019, In: Seminars in Arthritis and Rheumatism. 49, 3, p. 464-468 5 p.

    Research output: Contribution to journalArticlepeer-review

  8. Treatment in thrombotic antiphospholipid syndrome: a review

    Vadgama, T. S., Smith, A. & Bertolaccini, M. L., 1 Sep 2019, In: Lupus. 28, 10, p. 1181-1188 8 p.

    Research output: Contribution to journalReview articlepeer-review

  9. Aspectos destacados del Taller de Laboratorio de Anticuerpos Antifosfolípidos: XIII Congreso Argentino de Hemostasia y Trombosis, organizado por el GRUPO CAHT

    Adamczuk, Y., Annetta, E., Bertolaccini, M. L., Blanco, A. N., Duboscq, C., Mainetti, G., Martinuzzo, M., Remotti, L., Rossi, A. & Scazziota, A., 21 Jan 2019, (E-pub ahead of print) In: Hematologia. 22, 3, p. 326-347 22 p.

    Research output: Contribution to journalArticlepeer-review

  10. Clinical utility of the global anti-phospholipid syndrome score for risk stratification: A pooled analysis

    Sciascia, S., Radin, M., Sanna, G., Cecchi, I., Roccatello, D. & Bertolaccini, M. L., 1 Apr 2018, In: Rheumatology (United Kingdom). 57, 4, p. 661-665 5 p.

    Research output: Contribution to journalArticlepeer-review

  11. Recent advances in the management of systemic lupus erythematosus

    Sciascia, S., Radin, M., Roccatello, D., Sanna, G. & Bertolaccini, M. L., 2018, In: F1000Research. 7

    Research output: Contribution to journalReview articlepeer-review

  12. Closing the serological gap in the antiphospholipid syndrome: The value of "non-criteria" antiphospholipid antibodies

    Zohoury, N., Bertolaccini, M. L., Rodriguez-Garcia, J. L., Shums, Z., Ateka-Barrutia, O., Sorice, M., Norman, G. L. & Khamashta, M., Nov 2017, In: Journal of Rheumatology. 44, 11, p. 1597-1602 6 p.

    Research output: Contribution to journalArticlepeer-review

  13. Can we withdraw anticoagulation in patients with antiphospholipid syndrome after seroconvertion?

    Sciascia, S., Coloma-Bazán, E., Radin, M., Bertolaccini, M. L., López-Pedrera, C., Espinosa, G., Meroni, P. L., Cervera, R. & Cuadrado, M. J., 9 Sep 2017, (E-pub ahead of print) In: AUTOIMMUNITY REVIEWS. 16, 11, p. 1109-1114

    Research output: Contribution to journalArticlepeer-review

  14. Application of different lupus anticoagulant diagnostic algorithms to the same assay data leads to interpretive discrepancies in some samples

    Moore, G. W., Maloney, J. C., de Jager, N., Dunsmore, C. L., Gorman, D. K., Polgrean, R. F. & Bertolaccini, M. L., Jul 2017, In: Research and Practice in Thrombosis and Haemostasis. 1, 1, p. 62-68 7 p.

    Research output: Contribution to journalArticlepeer-review

  15. The Clinical Relevance of Noncriteria Antiphospholipid Antibodies

    Bertolaccini, M. L. & Sanna, G., 3 May 2017, In: Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticlepeer-review

  16. Evaluation of phosphatidylserine-dependent antiprothrombin antibody testing for the diagnosis of antiphospholipid syndrome: results of an international multicentre study

    Amengual, O., Forastiero, R., Sugiura-Ogasawara, M., Otomo, K., Oku, K., Favas, C., Delgado Alves, J., Žigon, P., Ambrožič, A., Tomšič, M., Ruiz-Arruza, I., Ruiz-Irastorza, G., Bertolaccini, M. L., Norman, G. L., Shums, Z., Arai, J., Murashima, A., Tebo, A. E., Gerosa, M., Meroni, P. L., & 5 othersRodriguez-Pintó, I., Cervera, R., Swadzba, J., Musial, J. & Atsumi, T., 1 Mar 2017, In: Lupus. 26, 3, p. 266-276 11 p.

    Research output: Contribution to journalArticlepeer-review

  17. Recent advances in understanding antiphospholipid syndrome

    Bertolaccini, M. L. & Sanna, G., 22 Dec 2016, (E-pub ahead of print) In: F1000Research. 5, 2908.

    Research output: Contribution to journalReview articlepeer-review

  18. Complement inhibition by hydroxychloroquine prevents placental and fetal brain abnormalities in antiphospholipid syndrome

    Bertolaccini, M. L., Contento, G., Lennen, R., Sanna, G., Blower, P. J., Ma, M. T., Sunassee, K. & Girardi, G., 1 Dec 2016, In: Journal of Autoimmunity. 75, p. 30-38

    Research output: Contribution to journalArticlepeer-review

  19. Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial

    Cohen, H., Hunt, B. J., Efthymiou, M., Arachchillage, D. R. J., Mackie, I. J., Clawson, S., Sylvestre, Y., Machin, S. J., Bertolaccini, M. L., Ruiz-Castellano, M., Muirhead, N., Doré, C. J., Khamashta, M. & Isenberg, D. A., 30 Sep 2016, In: The Lancet Haematology. 3, 9, p. e426-e436

    Research output: Contribution to journalArticlepeer-review

  20. Autoantibodies to domain 1 of beta 2 glycoprotein i determined using a novel chemiluminescence immunoassay demonstrate association with thrombosis in patients with antiphospholipid syndrome

    Mahler, M., Albesa, R., Zohoury, N., Bertolaccini, M. L., Ateka-Barrutia, O., Rodriguez-Garcia, J. L., Norman, G. L. & Khamashta, M., 1 Jul 2016, In: Lupus. 25, 8, p. 911-916 6 p.

    Research output: Contribution to journalArticlepeer-review

  21. Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: A multicentre prospective study of 1000 patients

    Euro-Phospholipid Project Group (European Forum on Antiphospholipid Antibodies), Bertolaccini, M. L. & Khamashta, M. A., 1 Jun 2015, In: Annals of the rheumatic diseases. 74, 6, p. 1011-1018 8 p.

    Research output: Contribution to journalArticlepeer-review

  22. Antibodies to domain I of β-2-glycoprotein I and IgA antiphospholipid antibodies in patients with 'seronegative' antiphospholipid syndrome

    Cousins, L., Pericleous, C., Khamashta, M., Bertolaccini, M. L., Ioannou, Y., Giles, I. & Rahman, A., Jan 2015, In: Annals of the rheumatic diseases. 74, 1, p. 317-319 3 p.

    Research output: Contribution to journalArticlepeer-review

  23. Antibodies to phosphatidylserine/prothrombin complex and the antiphospholipid syndrome

    Sciascia, S. & Bertolaccini, M., Oct 2014, In: Lupus. 23, 12, p. 1309-1312 4 p.

    Research output: Contribution to journalArticlepeer-review

  24. Thrombotic risk assessment in APS: the Global APS Score (GAPSS)

    Sciascia, S. & Bertolaccini, M., Oct 2014, In: Lupus. 23, 12, p. 1286-1287 2 p.

    Research output: Contribution to journalArticlepeer-review

  25. Validation of a commercially available kit to detect anti-phosphatidylserine/prothrombin antibodies in a cohort of systemic lupus erythematosus patients

    Sciascia, S., Sanna, G., Murru, V., Khamashta, M. A. & Bertolaccini, M. L., Mar 2014, In: Thrombosis Research. 133, 3, p. 451-454 4 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  26. Low-dose aspirin vs low-dose aspirin plus low-intensity warfarin in thromboprophylaxis: a prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies (ALIWAPAS)

    Cuadrado, M. J., Bertolaccini, M. L., Seed, P. T., Tektonidou, M. G., Aguirre, A., Mico, L., Gordon, C., Ruiz-Irastorza, G., Egurbide, M. V., Gil, A., Espinosa, G., Houssiau, F., Rahman, A., Martin, H., McHugh, N., Galindo, M., Akil, M., Amigo, M. C., Murru, V. & Khamashta, M. A., 2 Feb 2014, In: Rheumatology (Oxford, England). 53, 2, p. 275-284 10 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  27. Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome: A systematic review

    Sciascia, S., Sanna, G., Murru, V., Roccatello, D., Khamashta, M. A. & Bertolaccini, M. L., Feb 2014, In: Thrombosis and Haemostasis. 111, 2, p. 354-364 11 p.

    Research output: Contribution to journalReview articlepeer-review

  28. 14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends

    Bertolaccini, M. L., Amengual, O., Andreoli, L., Atsumi, T., Chighizola, C. B., Forastiero, R., de Groot, P., Lakos, G., Lambert, M., Meroni, P., Ortel, T. L., Petri, M., Rahman, A., Roubey, R., Sciascia, S., Snyder, M., Tebo, A. E., Tincani, A. & Willis, R., 2014, (E-pub ahead of print) In: AUTOIMMUNITY REVIEWS. 14 p.

    Research output: Contribution to journalArticlepeer-review

  29. Atherosclerosis and cardiovascular disease in systemic lupus erythematosus: effects of in vivo statin treatment

    Ruiz-Limon, P., Barbarroja, N., Perez-Sanchez, C., Aguirre, M. A., Bertolaccini, M. L., Khamashta, M. A., Rodriguez-Ariza, A., Almadén, Y., Segui, P., Khraiwesh, H., Gonzalez-Reyes, J. A., Villalba, J. M., Collantes-Estevez, E., Cuadrado, M. J. & Lopez-Pedrera, C., 2014, (E-pub ahead of print) In: Annals of the Rheumatic Diseases. 9 p.

    Research output: Contribution to journalArticlepeer-review

  30. Autoantibodies involved in neuropsychiatric manifestations associated with systemic lupus erythematosus: a systematic review

    Sciascia, S., Bertolaccini, M. L., Roccatello, D., Khamashta, M. A. & Sanna, G., 2014, (E-pub ahead of print) In: Journal of Neurology.

    Research output: Contribution to journalReview articlepeer-review

  31. The estimated frequency of antiphospholipid antibodies in young adults with cerebrovascular events: a systematic review

    Sciascia, S., Sanna, G., Khamashta, M. A., Cuadrado, M. J., Erkan, D., Andreoli, L., Bertolaccini, M. L. & on behalf of APS Action, 2014, (E-pub ahead of print) In: Annals of the Rheumatic Diseases. 6 p.

    Research output: Contribution to journalReview articlepeer-review

  32. The global anti-phospholipid syndrome score in primary APS

    Sciascia, S., Sanna, G., Murru, V., Roccatello, D., Khamashta, M. A. & Bertolaccini, M. L., 2014, (E-pub ahead of print) In: Rheumatology (Oxford, England). 5 p.

    Research output: Contribution to journalArticlepeer-review

  33. Thrombotic Risk Assessment in Systemic Lupus Erythematosus: Validation of the Global Antiphospholipid Syndrome Score (GAPSS) in a prospective cohort

    Sciascia, S., Cuadrado, M. J., Sanna, G., Murru, V., Roccatello, D., Khamashta, M. A. & Bertolaccini, M. L., 2014, (E-pub ahead of print) In: Arthritis care & research.

    Research output: Contribution to journalArticlepeer-review

  34. Antiphosphatidylserine/prothrombin antibodies in systemic lupus erythematosus

    Bertolaccini, M. L., Sciascia, S., Sanna, G. & Khamashta, M. A., Sep 2013, In: Journal of Rheumatology. 40, 9, p. 1620-1620 1 p., N/A.

    Research output: Contribution to journalLetterpeer-review

  35. GAPSS: the Global Anti-Phospholipid Syndrome Score

    Sciascia, S., Sanna, G., Murru, V., Roccatello, D., Khamashta, M. A. & Bertolaccini, M. L., Aug 2013, In: Rheumatology (Oxford, England). 52, 8, p. 1397-1403 7 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  36. Long-term follow-up of young adults with stroke

    Sciascia, S., Bertolaccini, M. L. & Ateka-Barrutia, O., 17 Jul 2013, In: JAMA : the journal of the American Medical Association. 310, 3, p. 321-321 1 p., N/A.

    Research output: Contribution to journalComment/debatepeer-review

  37. Prevalence of antibodies to prothrombin in solid phase (aPT) and to phosphatidylserine-prothrombin complex (aPS/PT) in patients with and without lupus anticoagulant

    Bertolaccini, M. L., Sciascia, S., Murru, V., Garcia-Fernandez, C., Sanna, G. & Khamashta, M. A., Feb 2013, In: Thrombosis and Haemostasis. 109, 2, p. 207-213 7 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  38. Central nervous system involvement in systemic lupus erythematosus: Overview on classification criteria

    Sciascia, S., Bertolaccini, M. L., Baldovino, S., Roccatello, D., Khamashta, M. A. & Sanna, G., Jan 2013, In: AUTOIMMUNITY REVIEWS. 12, 3, p. 426-429 4 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  39. Independent validation of the antiphospholipid score for the diagnosis of antiphospholipid syndrome

    Sciascia, S., Bertolaccini, M. L., Roccatello, D. & Khamashta, M. A., Jan 2013, In: Annals of the Rheumatic Diseases. 72, 1, p. 142-143 2 p., N/A.

    Research output: Contribution to journalLetterpeer-review

  40. The clinical relevance of IgA anticardiolipin and IgA anti-β2 glycoprotein I antiphospholipid antibodies: a systematic review

    Meijide, H., Sciascia, S., Sanna, G., Khamashta, M. A. & Bertolaccini, M. L., Jan 2013, In: AUTOIMMUNITY REVIEWS. 12, 3, p. 421-425 5 p., N/A.

    Research output: Contribution to journalReview articlepeer-review

  41. Anti-phosphatidylethanolamine antibody, thromboembolic events and the antiphospholipid syndrome

    Staub, H. L., Bertolaccini, M. L. & Khamashta, M. A., Dec 2012, In: AUTOIMMUNITY REVIEWS. 12, 2, p. 230-234 5 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  42. Clinical accuracy for diagnosis of antiphospholipid syndrome in systemic lupus erythematosus: evaluation of 23 possible combinations of antiphospholipid antibody specificities

    Sciascia, S., Murru, V., Sanna, G., Roccatello, D., Khamashta, M. A. & Bertolaccini, M. L., Dec 2012, In: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 10, 12, p. 2512-2518 7 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  43. The clinical value of testing for antibodies to phosphatidylethanolamine (aPE) in patients with systemic lupus erythematosus (SLE)

    Bertolaccini, M. L., Murru, V., Sciascia, S., Sanna, G. & Khamashta, M. A., Dec 2012, In: Thrombosis Research. 130, 6, p. 914-918 5 p., N/A.

    Research output: Contribution to journalArticlepeer-review

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