Personal profile
Research interests
Education/Academic qualification
Doctor of Philosophy, Studies on the Structure of the Genome of <i>Haloferax volcanii</i>, Dalhousie University
Award Date: 1 Jan 1991
Bachelor of Science, University of Alberta
Award Date: 1 Jan 1983
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education
Fingerprint
- 1 Similar Profiles
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Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., Bretherick, A. D., Richardson, T. G., Klughammer, J., Iotchkova, V., Sharp, G., Al Khleifat, A., Shatunov, A., Iacoangeli, A., McArdle, W. L. & Ho, K. M. & 31 others, , Sept 2021, In: Nature Genetics. 53, 9, p. 1311-1321 11 p.Research output: Contribution to journal › Article › peer-review
346 Citations (Scopus) -
Recalibrating the epigenetic clock: Implications for assessing biological age in the human cortex
Shireby, G. L., Davies, J. P., Francis, P. T., Burrage, J., Walker, E. M., Neilson, G. W. A., Dahir, A., Thomas, A. J., Love, S., Smith, R. G., Lunnon, K., Kumari, M., Schalkwyk, L. C., Morgan, K., Brookes, K., Hannon, E. & Mill, J., 1 Dec 2020, In: Brain. 143, 12, p. 3763-3775 13 p.Research output: Contribution to journal › Article › peer-review
Open Access148 Citations (Scopus) -
Bigmelon: Tools for analysing large DNA methylation datasets
Gorrie-Stone, T. J., Smart, M. C., Saffari, A., Malki, K., Hannon, E., Burrage, J., Mill, J., Kumari, M. & Schalkwyk, L. C., 15 Mar 2019, In: BIOINFORMATICS. 35, 6, p. 981-986 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (Scopus)176 Downloads (Pure) -
DNA methylation aging clocks: Challenges and recommendations
Bell, C. G., Lowe, R., Adams, P. D., Baccarelli, A. A., Beck, S., Bell, J. T., Christensen, B. C., Gladyshev, V. N., Heijmans, B. T., Horvath, S., Ideker, T., Issa, J. P. J., Kelsey, K. T., Marioni, R. E., Reik, W., Relton, C. L., Schalkwyk, L. C., Teschendorff, A. E., Wagner, W. & Zhang, K. & 1 others, , 25 Nov 2019, In: Genome Biology. 20, 1, 249.Research output: Contribution to journal › Review article › peer-review
Open Access748 Citations (Scopus) -
Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue
Wong, C. C. Y., Smith, R., Hannon, E., Ramaswami, G., Parikshak, N. N., Assary, E., Troakes, C., Poschmann, J., Schalkwyk, L. C., Sun, W., Prabhakar, S., Geschwind, D. H. & Mill, J., 1 Jul 2019, In: Human Molecular Genetics. 28, 13, p. 2201-2211 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile73 Citations (Scopus)233 Downloads (Pure)
Projects
- 43 Finished
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An animal model to identify common biological mechanisms for type 2 diabetes mellitus and depression
Schalkwyk, L. (Primary Investigator), Fernandes, C. (Co-Investigator), Ismail, K. (Co-Investigator), Thuret, S. (Co-Investigator) & academic, A. (Co-Investigator)
1/01/2015 → 31/12/2017
Project: Research
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Trans-Generational Study of the Effects of Sex and Development Stage on the Behaviour of the Offspring of Aged Fathers
Fernandes, C. (Primary Investigator), Mill, J. (Co-Investigator), Reichenberg, A. (Co-Investigator) & Schalkwyk, L. (Co-Investigator)
Icahn School of Medicine at Mount Sinai
1/06/2014 → 31/05/2016
Project: Research
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Gene regulatory variation in the developing human brain and its role in neuropsychiatric disorders
Bray, N. (Primary Investigator), Dobson, R. (Co-Investigator), Lewis, C. (Co-Investigator) & Schalkwyk, L. (Co-Investigator)
3/03/2014 → 2/03/2017
Project: Research
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Disentangling Heterogeneity in Autism Spectrum Disorder
Bolton, P. (Primary Investigator) & Schalkwyk, L. (Co-Investigator)
1/09/2013 → 31/08/2014
Project: Research
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Methylomic profiling in schizophrenia: Towards an integrated genetic-epigenetic approach.
Schalkwyk, L. (Primary Investigator), Breen, G. (Co-Investigator) & Murray, R. (Co-Investigator)
31/08/2013 → 30/08/2016
Project: Research
Activities
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BMC GENOMICS (Journal)
Schalkwyk, L. (Editor)
2010 → …Activity: Publication peer-review and editorial work › Editorial activity
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European systems genetics network (SYSGENET) Co
Schalkwyk, L. (Chair)
2008 → 2013Activity: Other › Types of External academic engagement - Membership of external research organisation
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Mammalian Genome (Journal)
Schalkwyk, L. (Editorial board member)
2007 → …Activity: Publication peer-review and editorial work › Editorial activity
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Frontiers in Neurogenomics (Journal)
Schalkwyk, L. (Editorial board member)
2007 → …Activity: Publication peer-review and editorial work › Editorial activity
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Complex Trait Consortium
Schalkwyk, L. (Member)
2002 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
Datasets
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Tissue-specific patterns of allelically-skewed DNA methylation
Marzi, S. J., Meaburn, E. L., Dempster, E. L., Lunnon, K., Paya-Cano, J. L., Smith, R. G., Volta, M., Troakes, C., Schalkwyk, L. C. & Mill, J., Taylor & Francis, 20 Jan 2016
DOI: 10.6084/m9.figshare.2065608
Dataset