Personal profile
Biographical details
Professor Lucy Chappell is Professor in Obstetrics at King’s College London, Honorary Consultant Obstetrician at Guy’s and St Thomas’ NHS Foundation Trust and an NIHR Senior Investigator. She runs a research programme investigating prediction and prevention of adverse pregnancy outcomes, particularly in women with pre-existing co-morbidities such as chronic hypertension and chronic kidney disease, using randomised controlled trials and observational studies. She has subspecialty training in maternal-fetal medicine and a Masters in higher education, supervising higher degree students from obstetric, nephrology, general practice and midwifery backgrounds. She is Chair of the NIHR HTA Clinical Evaluation and Trials committee, Chair of the NIHR Artificial Intelligence for Multiple Long-Term Conditions committee and Deputy Chair of the MRC/ NIHR Clinical Academic Research Partnership committee. She is national pregnancy lead for the RECOVERY trial in COVID-19 and vaccine lead for the Royal College of Obstetricians and Gynaecologists.
Research interests
Pregnancy hypertension
Education/Academic qualification
Master of Education, King's College London
Award Date: 1 Jan 2011
Doctor of Philosophy, University of London
Award Date: 1 Jan 2001
Bachelor of Medicine and Bachelor of Surgery, University of Cambridge
Award Date: 1 Jan 1992
Bachelor of Science, University of London
Award Date: 1 Jan 1990
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 5 Gender Equality -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities -
SDG 11 Sustainable Cities and Communities -
SDG 15 Life on Land -
SDG 16 Peace, Justice and Strong Institutions -
SDG 17 Partnerships for the Goals
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Collaborations and top research areas from the last five years
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Ethnic disparities in hypertensive disorders of pregnancy
Conti-Ramsden, F., de Marvao, A. & Chappell, L. C., Jun 2025, In: REPRODUCTION. 169, 6, e250049.Research output: Contribution to journal › Review article › peer-review
Open Access5 Citations (Scopus) -
Evaluating the real-world scale-up of the CRADLE Vital Signs Alert intervention into routine maternity care in Sierra Leone (CRADLE-5): a stepped-wedge, type 2 hybrid implementation–effectiveness, cluster-randomised controlled trial
Ridout, A., L Moses, F., Fernandez Turienzo, C., Herm-Singh, S., Beoku-Betts, C., Businge, E., Goodhart, V., Hurrell, A., Kamara, D., Kamara, J., Koroma, K., Kuhrt, K., Martin, A., Momoh, M., Seed, P., Sam, B., Samura, S., Williams, P. T., Chappell, L. & Smart, F. & 6 others, , Dec 2025, In: The Lancet Obstetrics, Gynaecology, & Woman's Health. 1, 4, p. e270-e280 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Point-of-Care Placental Growth Factor for Predicting Adverse Outcomes in Sierra Leone
Kuhrt, K., Cole, R., M'Bayoh, M., Mabula-Bwalya, C., Hurrell, A., Ridout, A., Fernandez-Turienzo, C., Seed, P. T., Chappell, L. C., Bramham, K., Shennan, A. H. & Pineapple Study Group, Oct 2025, In: Hypertension (Dallas, Tex. : 1979). 82, 10, p. 1719-1728 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus) -
The Contribution of Hypertensive Disorders of Pregnancy to Neonatal Unit Admissions and Iatrogenic Preterm Delivery at < 34+0 Weeks' Gestation in the UK: A Population-Based Study Using the National Neonatal Research Database
Conti-Ramsden, F., Fleminger, J., Lanoue, J., Chappell, L., Battersby, C. & the UK Neonatal Collaborative, 6 Jan 2025, In: BJOG: An International Journal of Obstetrics and Gynaecology. 132, 3, p. 306-317 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)2 Downloads (Pure) -
What matters to you? Improving the adoption of shared decision-making for birth planning in women with chronic hypertension: a multicentre multiple methods study
Whybrow, R., Chappell, L., Webster, L., Girling, J., Brown, H., Wilson, H., Green, M. & Sandall, J., 17 Jun 2025, (E-pub ahead of print) In: BMJ Open. 15, 6, e094607.Research output: Contribution to journal › Article › peer-review
Open AccessFile
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CRADLE-B: Community-based Research for Assessment, Detection and management of hypertension after pregnancy for LifetimE Benefit (CRADLE-B)
Bramham, K. (Primary Investigator), Chappell, L. (Co-Investigator), Charakida, M. (Co-Investigator), Fernandez Turienzo, C. (Co-Investigator), Shennan, A. (Co-Investigator) & de Marvao, A. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/03/2025 → 28/02/2030
Project: Research
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PAPAGAIO: Preterm pre-eclampsiA: PlAcental Growth factor testing for reduction of Adverse Outcomes
Shennan, A. (Primary Investigator), Bramham, K. (Co-Investigator), Chappell, L. (Co-Investigator) & Ridout, A. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/07/2024 → 30/06/2027
Project: Research
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Optimising the management of blood pressure following following hypertensive pregnancy to reduce the cardiovascular risk.
Chappell, L. (Primary Investigator)
NIHR National Institute For Health & Care Research
1/07/2022 → 30/06/2027
Project: Research
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Cardiac and vascular disease prevention after hypertensive pregnancy: insights from AI-derived, multi-organ, hypertensive disease progression models
Lamata de la Orden, P. (Primary Investigator) & Chappell, L. (Co-Investigator)
1/02/2022 → 31/01/2027
Project: Research
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CRIBS: NIHR Global Health Research Group: Implementation of simple solutions to reduce maternal and neonatal mortality and build research capacity in Sierra Leone
Shennan, A. (Primary Investigator), Boulding, H. (Co-Investigator), Bramham, K. (Co-Investigator), Chappell, L. (Co-Investigator), Fernandez Turienzo, C. (Co-Investigator), Leather, A. (Co-Investigator), November, L. (Co-Investigator) & Sandall, J. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/09/2021 → 31/03/2026
Project: Research
Activities
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RCOG Annual Academic Meeting
Chappell, L. (Organiser)
25 Feb 2021 → 26 Feb 2021Activity: Participating in or organising an event › Participation in conference
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Delivery timing for preterm preeclampsia
Chappell, L. (Speaker)
Jan 2021Activity: Talk or presentation › Invited talk
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Management of women with late preterm pre-eclampsia (PHOENIX trial) – journal club
Chappell, L. (Speaker)
Dec 2020Activity: Talk or presentation › Invited talk
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Update on PlGF testing in suspected pre-eclampsia
Chappell, L. (Speaker)
Nov 2020Activity: Talk or presentation › Invited talk
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NIHR Artificial Intelligence in Multiple Long-Term Conditions committee (External organisation)
Chappell, L. (Chair)
Nov 2020 → …Activity: Membership › Membership of committee
Prizes
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Best supervisor, Academic Foundation Programme 2018-19, Guy's & St Thomas' NHS Trust
Chappell, L. (Recipient), Aug 2019
Prize: Prize (including medals and awards)
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BMFMS Annual Meeting late breaking oral presentation prize (PITCHES)
Chappell, L. (Recipient), Mar 2019
Prize: Prize (including medals and awards)
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BMJ Awards 2020: Women's Health Category - highly commended
Chappell, L. (Recipient), Feb 2020
Prize: Prize (including medals and awards)
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Fellowship of the Academy of Medical Sciences
Chappell, L. (Recipient), May 2020
Prize: Election to learned society