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  1. The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

    Krastev, D. B., Li, S., Sun, Y., Wicks, A. J., Hoslett, G., Weekes, D., Badder, L. M., Knight, E. G., Marlow, R., Pardo, M. C., Yu, L., Talele, T. T., Bartek, J., Choudhary, J. S., Pommier, Y., Pettitt, S. J., Tutt, A. N. J., Ramadan, K. & Lord, C. J., 10 Jan 2022, In: Nature Cell Biology. 24, 1, p. 62-73 12 p.

    Research output: Contribution to journalArticlepeer-review

  2. Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

    Zatreanu, D., Robinson, H. M. R., Alkhatib, O., Boursier, M., Finch, H., Geo, L., Grande, D., Grinkevich, V., Heald, R. A., Langdon, S., Majithiya, J., McWhirter, C., Martin, N. M. B., Moore, S., Neves, J., Rajendra, E., Ranzani, M., Schaedler, T., Stockley, M., Wiggins, K., & 41 othersBrough, R., Sridhar, S., Gulati, A., Shao, N., Badder, L. M., Novo, D., Knight, E. G., Marlow, R., Haider, S., Callen, E., Hewitt, G., Schimmel, J., Prevo, R., Alli, C., Ferdinand, A., Bell, C., Blencowe, P., Bot, C., Calder, M., Charles, M., Curry, J., Ekwuru, T., Ewings, K., Krajewski, W., MacDonald, E., McCarron, H., Pang, L., Pedder, C., Rigoreau, L., Swarbrick, M., Wheatley, E., Willis, S., Wong, A. C., Nussenzweig, A., Tijsterman, M., Tutt, A., Boulton, S. J., Higgins, G. S., Pettitt, S. J., Smith, G. C. M. & Lord, C. J., Dec 2021, In: Nature Communications. 12, 1, 3636.

    Research output: Contribution to journalArticlepeer-review

  3. Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer

    Yeow, Z. Y., Lambrus, B. G., Marlow, R., Zhan, K. H., Durin, M. A., Evans, L. T., Scott, P. M., Phan, T., Park, E., Ruiz, L. A., Moralli, D., Knight, E. G., Badder, L. M., Novo, D., Haider, S., Green, C. M., Tutt, A. N. J., Lord, C. J., Chapman, J. R. & Holland, A. J., 17 Sep 2020, In: Nature. 585, 7825, p. 447-452 6 p.

    Research output: Contribution to journalArticlepeer-review

  4. Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer

    Cheung, A., Opzoomer, J. W., Ilieva, K. M., Gazinska, P., Hoffmann, R. M., Mirza, H., Marlow, R., Francesch-Domenech, E., Fittall, M. W., Dominguez Rodriguez, D., Clifford, A., Badder, L., Patel, N., Mele, S., Pellizzari, G., Bax, H. J., Crescioli, S., Petranyi, G., Larcombe-Young, D., Josephs, D. H., & 9 othersCanevari, S., Figini, M., Pinder, S. E., Nestle, F. O., Gillett, C., Spicer, J., Grigoriadis, A., Tutt, A. & Karagiannis, S. N., 15 Oct 2018, In: Clinical Cancer Research. 24, 20, p. 5098-5111

    Research output: Contribution to journalArticlepeer-review

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