Projects per year
Projects
- 40 Finished
Search results
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Finished
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Targeting the myofilaments to correct heart muscle dysfunction
1/09/2019 → 31/08/2022
Project: Research
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BHF Research Excellence Award
Shah, A., Botnar, R., Chowienczyk, P., Eaton, P., Garcia-Manyes, S., Gautel, M., Giacca, M., Irving, M., Lamata de la Orden, P., Marber, M., Mayr, M., Otsu, K., Ourselin, S., Parsons, M., Razavi, R., Schnabel, J., Shanahan, C., Xu, Q. & Phinikaridou, A.
1/04/2019 → 31/03/2024
Project: Research
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Regulation of Contraction by the thick filaments in skeletal muscle
1/12/2018 → 3/09/2023
Project: Research
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Cardiac thick filament modulators: A potential new class of heart failure therapeutics
1/10/2017 → 31/12/2018
Project: Research
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Dual-filament regulation optimises the performance of heart muscle
1/04/2017 → 31/03/2022
Project: Research
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King’s NMR Facility for structural biology, metabolic profiling and drug discovery
Conte, M., Avkiran, M., Blower, P., Dodding, M., Eaton, P., Gautel, M., Irving, M., Malim, M., Marber, M., Mayr, M., McDonnell, J., Otsu, K., Pastore, A., Pfuhl, M., Poston, L., Shah, A., Shanahan, C., Shattock, M. & Williamson, C.
BHF British Heart Foundation, Wellcome Trust
1/01/2017 → 31/12/2021
Project: Research
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A novel signaling pathway in the regulation of cardiac contractility: mechano-sensing in the myosin filaments
1/09/2016 → 31/08/2019
Project: Research
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Myosin Binding Protein-C: a key regulator of cardiac output
Kampourakis, T., Gautel, M. & Irving, M.
1/03/2016 → 31/03/2020
Project: Research
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King's NMR Facility for metabolic profiling, structural biology and drug discovery
Conte, M., Dodding, M., Irving, M., Malim, M. & Mason, J.
1/10/2015 → 30/09/2020
Project: Research
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Myosin-linked mechanisms for the regulation of muscle contraction
1/09/2015 → 31/08/2018
Project: Research
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High Resolution Ultrastructural Imaging Core Facility. A multiplatform electron microscopyfacility, with enabling high-resolution 3D and cryo-EM imaging from the nano to meso scale atKing's College London
Fleck, R., Botnar, R., Burrone, J., Houart, C., Irving, M., McGrath, J., Miller, C., Ng, T., Steel, K. & Watt, F.
1/07/2014 → 30/06/2019
Project: Research
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Cypher Scanning Probe Microscope (SPM) System
Garcia-Manyes, S. & Irving, M.
31/01/2014 → 31/03/2014
Project: Research
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The in situ mechanism of calcium sensitization by cardiovascular drugs that target troponon
CIHR Canadian Institutes of Health Research
1/06/2013 → 31/05/2016
Project: Research
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Multiparametric advanced fluorescence imaging strategies for in situ analysis of live cell signalling
Irving, M., Ameer-Beg, S., Cox, S., Gautel, M., Geissmann, F., Hughes, S., Jones, G. E., Owen, D., Parsons, M., Ridley, A., Suhling, K. & Watt, F.
1/02/2013 → 12/02/2018
Project: Research
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In silico and in vitro studies of cell-cell interactions leading to neoplasia
1/11/2012 → 31/10/2017
Project: Research
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Myosin regulatory light chain: modulator of cardiac function in health and disease
1/11/2012 → 30/11/2015
Project: Research
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Coupling the molecular motor Kinesin-1 to new cargo, functions and diseases
1/07/2012 → 30/06/2017
Project: Research
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A chemical approach to understanding cell division
Eggert, U., Irving, M. & Roth, F.
1/06/2011 → 31/05/2016
Project: Research
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Fluorescent probes of protein conformation in cells
Fraternali, F., Irving, M. & Sun, Y.
1/10/2010 → 30/09/2013
Project: Research
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Non-muscle myosin II as an integrator of pliability, integrin-mediated adhesion and growth factors in cell migration
1/10/2009 → 30/09/2014
Project: Research
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New tools for optical proteomics
Richards, D., Coolen, T., Irving, M., Ng, T., Suhling, K. & Watson, T.
1/10/2009 → 31/03/2011
Project: Research
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Control of myofilament calcium-sensitivity: a key determinant of the physiology and pathology of heart muscle
1/03/2009 → 28/02/2014
Project: Research
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BHF Centre of Research Excellence
Avkiran, M., Blower, P., Botnar, R., Chowienczyk, P., Eaton, P., Ehler, E., Garcia-Manyes, S., Gautel, M., Geissmann, F., Hussain, M., Irving, M., Kalra, L., Marber, M., Mayr, M., Nagel, E., Otsu, K., Razavi, R., Ridley, A., Shah, A., Shanahan, C., Smith, N., Xu, Q., Alastruey, J., Ameer-Beg, S., Bishop, M., Brain, S., Burgoyne, J., Conte, M., Dhanjal, T., Eminaga, S., Eykyn, T., Gee, T., Heintzmann, R., Hughes, S., Iskratsch, T., Ivetic, A., Jones, G. E., Kentish, J., Lamata de la Orden, P., Lombardi, G., Mullen, G., Okonko, D., Parsons, M., Pfuhl, M., Phinikaridou, A., Rodaway, A., Shattock, M., Sinkus, R., Springett, R., Steiner, R., Stroud, M., Sun, Y., Wardle, F., Warren, D., Webb, A., Zampetaki, A., Zeng, L. & academic, A.
1/01/2008 → 31/03/2019
Project: Research
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Optical proteomic technology for in-situ analysis of protein interaction networks
Irving, M., Heintzmann, R., Ng, T., Richards, D. & Suhling, K.
EPSRC Engineering and Physical Sciences Research Council
24/10/2005 → 23/02/2010
Project: Research
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Interdisciplinary Research Network: in situ functional proteomic technology
Irving, M., Ng, T. & Richards, D.
EPSRC Engineering and Physical Sciences Research Council
15/08/2005 → 14/08/2008
Project: Research
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Molecular mechanisms of cardiac muscle regulation: role of change in the conformation of Troponin C in situ
1/03/2005 → 28/02/2009
Project: Research
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Energy Transduction in Muscle and related motility systems - structure, function and mechanics
1/09/2000 → 31/08/2004
Project: Research
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Molecular basis of contraction in skeletal muscle: synchrotron X-ray diffraction studies with isolated muscle fibres
1/09/2000 → 31/08/2005
Project: Research
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Coupling between force production and ATP utilisation in skeletal muscle
1/10/1997 → 30/09/2000
Project: Research