Research output per year
Research output per year
- 20 results
Search results
-
2022
Rubicon-regulated beta-1 adrenergic receptor recycling protects the heart from pressure overload
Akazawa, Y., Taneike, M., Ueda, H., Kitazume-Taneike, R., Murakawa, T., Sugihara, R., Yorifuji, H., Nishida, H., Mine, K., Hioki, A., Omiya, S., Nakayama, H., Yamaguchi, O., Yoshimori, T., Sakata, Y. & Otsu, K., 7 Jan 2022, (E-pub ahead of print) In: Scientific Reports. 12, 1, 41.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
2021
Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice
Ito, J., Omiya, S., Rusu, M-C., Ueda, H., Murakawa, T., Tanada, Y., Abe, H., Nakahara, K., Asahi, M., Taneike, M., Nishida, K., Shah, A. & Otsu, K., 2 Feb 2021, In: eLife. 10, p. 1-23 23 p., e62174.Research output: Contribution to journal › Article › peer-review
Open AccessFile60 Citations (Scopus)37 Downloads (Pure) -
2020
Cytokine mRNA degradation in cardiomyocytes restrains sterile inflammation in pressure overloaded hearts
Omiya, S., Omori, Y., Taneike, M., Murakawa, T., Ito, J., Tanada, Y., Nishida, K., Yamaguchi, O., Satoh, T., Shah, A. M., Akira, S. & Otsu, K., 25 Feb 2020, In: Circulation. 141, 8, p. 667-677 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)186 Downloads (Pure) -
2019
Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice
Kitazume-Taneike, R., Taneike, M., Omiya, S., Misaka, T., Nishida, K., Yamaguchi, O., Akira, S., Shattock, M. J., Sakata, Y. & Otsu, K., 30 Jul 2019, In: Biochemical and Biophysical Research Communications. 515, 3, p. 442-447Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)132 Downloads (Pure) -
A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy
Murakawa, T., Okamoto, K., Omiya, S., Taneike, M., Yamaguchi, O. & Otsu, K., 8 Jan 2019, In: Cell Reports. 26, 2, p. 338-345.e6Research output: Contribution to journal › Article › peer-review
Open AccessFile59 Citations (Scopus)90 Downloads (Pure) -
2018
FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice
Misaka, T., Murakawa, T., Nishida, K., Omori, Y., Taneike, M., Omiya, S., Molenaar, C., Uno, Y., Yamaguchi, O., Takeda, J., Shah, A. M. & Otsu, K., Jan 2018, In: Journal of Molecular and Cellular Cardiology. 114, p. 93-104Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)188 Downloads (Pure) -
2016
MTOR hyperactivation by ablation of tuberous sclerosis complex 2 in the mouse heart induces cardiac dysfunction with the increased number of small mitochondria mediated through the down-regulation of autophagy
Taneike, M., Nishida, K., Omiya, S., Zarrinpashneh, E., Misaka, T., Kitazume-Taneike, R., Austin, R., Takaoka, M., Yamaguchi, O., Gambello, M. J., Shah, A. M. & Otsu, K., 29 Mar 2016, In: PL o S One . 11, 3, e0152628.Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Citations (Scopus)220 Downloads (Pure) -
Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation
Omiya, S., Omori, Y., Taneike, M., Protti, A., Yamaguchi, O., Akira, S., Shah, A., Nishida, K. & Otsu, K., Dec 2016, In: American Journal of Physiology (Heart and Circulatory Physiology). 311, 6, p. H1485-H1497Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
2015
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
Murakawa, T., Yamaguchi, O., Hashimoto, A., Hikoso, S., Takeda, T., Oka, T., Yasui, H., Ueda, H., Akazawa, Y., Nakayama, H., Taneike, M., Misaka, T., Omiya, S., Shah, A. M., Yamamoto, A., Nishida, K., Ohsumi, Y., Okamoto, K., Sakata, Y. & Otsu, K., 6 Jul 2015, In: Nature Communications. 6, 1, p. 1-14 14 p., 7527.Research output: Contribution to journal › Article › peer-review
Open AccessFile332 Citations (Scopus)200 Downloads (Pure) -
The role of autophagic degradation in the heart
Nishida, K., Taneike, M. & Otsu, K., 1 Jan 2015, In: Journal of Molecular and Cellular Cardiology. 78, p. 73-79 7 p.Research output: Contribution to journal › Article › peer-review
47 Citations (Scopus) -
2013
Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading
Oyabu, J., Yamaguchi, O., Hikoso, S., Takeda, T., Oka, T., Murakawa, T., Yasui, H., Ueda, H., Nakayama, H., Taneike, M., Omiya, S., Shah, A. M., Nishida, K. & Otsu, K., 29 Nov 2013, In: Biochemical and Biophysical Research Communications. 441, 4, p. 787-792 6 p.Research output: Contribution to journal › Article › peer-review
45 Citations (Scopus) -
Rheb (Ras Homologue Enriched in Brain)-dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Becomes Indispensable for Cardiac Hypertrophic Growth after Early Postnatal Period
Tamai, T., Yamaguchi, O., Hikoso, S., Takeda, T., Taneike, M., Oka, T., Oyabu, J., Murakawa, T., Nakayama, H., Uno, Y., Horie, K., Nishida, K., Sonenberg, N., Shah, A. M., Takeda, J., Komuro, I. & Otsu, K., 5 Apr 2013, In: Journal of Biological Chemistry. 288, 14, p. 10176-10187 12 p., N/A.Research output: Contribution to journal › Article › peer-review
39 Citations (Scopus) -
2012
Cooperation between proteolytic systems in cardiomyocyte recycling
Yamaguchi, O., Taneike, M. & Otsu, K., 1 Oct 2012, In: Cardiovascular Research. 96, 1, p. 46-52 7 p.Research output: Contribution to journal › Literature review › peer-review
24 Citations (Scopus) -
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
Oka, T., Hikoso, S., Yamaguchi, O., Taneike, M., Takeda, T., Tamai, T., Oyabu, J., Murakawa, T., Nakayama, H., Nishida, K., Akira, S., Yamamoto, A., Komuro, I. & Otsu, K., 10 May 2012, In: NATURE. 485, 7397, p. 251-255 6 p.Research output: Contribution to journal › Article › peer-review
874 Citations (Scopus) -
2011
Calpain protects the heart from hemodynamic stress
Taneike, M., Mizote, I., Morita, T., Watanabe, T., Hikoso, S., Yamaguchi, O., Takeda, T., Oka, T., Tamai, T., Oyabu, J., Murakawa, T., Nakayama, H., Nishida, K., Takeda, J., Mochizuki, N., Komuro, I. & Otsu, K., 16 Sept 2011, In: Nucleic Acids research and the Journal of Biological Chemistry. 286, 37, p. 32170-7 8 p.Research output: Contribution to journal › Article › peer-review
47 Citations (Scopus) -
Rheb-mTOR Signaling Pathway Regulates Protein Synthesis but Not Degradation in Post Neonatal Cardiomyocyte Growth
Tamai, T., Hikoso, S., Murakawa, T., Oyabu, J., Oka, T., Taneike, M., Takeda, T., Yamaguchi, O., Nakayama, H., Nishida, K., Komuro, I. & Otsu, K., 22 Nov 2011, In: Circulation (Baltimore). 124, 21, p. - 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
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2010
Activation of MTK1/MEKK4 induces cardiomyocyte death and heart failure
Mizote, I., Yamaguchi, O., Hikoso, S., Takeda, T., Taneike, M., Oka, T., Tamai, T., Oyabu, J., Matsumura, Y., Nishida, K., Komuro, I., Hori, M. & Otsu, K., Feb 2010, In: Journal of Molecular and Cellular Cardiology. 48, 2, p. 302-309 8 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Inhibition of autophagy in the heart induces age-related cardiomyopathy
Taneike, M., Yamaguchi, O., Nakai, A., Hikoso, S., Takeda, T., Mizote, I., Oka, T., Tamai, T., Oyabu, J., Murakawa, T., Nishida, K., Shimizu, T., Hori, M., Komuro, I., Shirasawa, T., Mizushima, N. & Otsu, K., 1 Jul 2010, In: Autophagy. 6, 5, p. 600-606 7 p.Research output: Contribution to journal › Article › peer-review
355 Citations (Scopus) -
2009
Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes
Omiya, S., Hikoso, S., Imanishi, Y., Saito, A., Yamaguchi, O., Takeda, T., Mizote, I., Oka, T., Taneike, M., Nakano, Y., Matsumura, Y., Nishida, K., Sawa, Y., Hori, M. & Otsu, K., Jan 2009, In: Journal of Molecular and Cellular Cardiology. 46, 1, p. 59-66 8 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
The IκB Kinase β/Nuclear Factor κB Signaling Pathway Protects the Heart From Hemodynamic Stress Mediated by the Regulation of Manganese Superoxide Dismutase Expression
Hikoso, S., Yamaguchi, O., Nakano, Y., Takeda, T., Omiya, S., Mizote, I., Taneike, M., Oka, T., Tamai, T., Oyabu, J., Uno, Y., Matsumura, Y., Nishida, K., Suzuki, K., Kogo, M., Hori, M. & Otsu, K., 2 Jul 2009, In: Circulation Research. 105, 1, p. 70-79 10 p.Research output: Contribution to journal › Article › peer-review
58 Citations (Scopus)