King's College London

Research portal

Dr Manish Sinha

  1. Intensive compared with less intensive blood pressure control to prevent adverse cardiac remodelling in children with chronic kidney disease (HOT-KID): a parallel-group, open-label, multicentre, randomised, controlled trial

    Sinha, M. D., Gu, H., Douiri, A., Cansick, J., Finlay, E., Gilbert, R., Kerecuk, L., Lunn, A., Maxwell, H., Morgan, H., Shenoy, M., Shroff, R., Subramaniam, P., Tizard, J., Tse, Y., Rezavi, R., Simpson, J. M. & Chowienczyk, P. J., 4 Jan 2023, In: The Lancet Child & Adolescent Health. 7, 1, p. 26-36 11 p.

    Research output: Contribution to journalArticlepeer-review

  2. Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT

    UPBEAT Consortium, Dec 2022, In: International Journal of Obesity. 46, 12, p. 2145-2155 11 p.

    Research output: Contribution to journalArticlepeer-review

  3. Percutaneous Venous Reconstruction for Central Thrombosis-Associated Chylothorax: A Safe and Efficacious Option

    Deogaonkar, G., Sinha, M. D., Jones, M., Calder, F., Karunanithy, N. & Qureshi, S. A., 20 Oct 2021, In: JACC: Case Reports. 3, 14, p. 1569-1575 7 p.

    Research output: Contribution to journalArticlepeer-review

  4. Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease—A Pediatric Perspective

    Grund, A., Sinha, M. D., Haffner, D. & Leifheit-Nestler, M., 4 Aug 2021, In: Frontiers in Pediatrics. 9, 702719.

    Research output: Contribution to journalReview articlepeer-review

  5. Hemodiafiltration maintains a sustained improvement in blood pressure compared to conventional hemodialysis in children—the HDF, heart and height (3H) study

    De Zan, F., Smith, C., Duzova, A., Bayazit, A., Stefanidis, C. J., Askiti, V., Azukaitis, K., Canpolat, N., Agbas, A., Anarat, A., Aoun, B., Bakkaloglu, S. A., Borzych-Dużałka, D., Bulut, I. K., Habbig, S., Krid, S., Licht, C., Litwin, M., Obrycki, L., Paglialonga, F., & 11 othersRanchin, B., Samaille, C., Shenoy, M., Sinha, M. D., Spasojevic, B., Yilmaz, A., Fischbach, M., Schmitt, C. P., Schaefer, F., Vidal, E. & Shroff, R., Aug 2021, In: Pediatric Nephrology. 36, 8, p. 2393-2403 11 p.

    Research output: Contribution to journalArticlepeer-review

  6. Measurement of SBP at home by parents using hand-held Doppler device and aneroid sphygmomanometer: a single-centre experience

    Newton, J., Singh, C. & Sinha, M. D., 1 May 2021, In: Journal of hypertension. 39, 5, p. 904-910 7 p.

    Research output: Contribution to journalArticlepeer-review

  7. Early ventricular contraction in children with primary hypertension relates to left ventricular mass

    Gu, H., Singh, C., Li, Y., Simpson, J., Chowienczyk, P. & Sinha, M. D., 1 Apr 2021, In: Journal of hypertension. 39, 4, p. 711-717 7 p.

    Research output: Contribution to journalArticlepeer-review

  8. Acute Kidney Injury in Critically Ill Children Is Not all Acute: Lessons Over the Last 5 Years

    Hessey, E., Melhem, N., Alobaidi, R., Ulrich, E., Morgan, C., Bagshaw, S. M. & Sinha, M. D., 15 Mar 2021, In: Frontiers in Pediatrics. 9, 648587.

    Research output: Contribution to journalReview articlepeer-review

  9. Associations between deprivation, geographic location, and access to pediatric kidney care in the United Kingdom

    Plumb, L. A., Sinha, M. D., Casula, A., Inward, C. D., Marks, S. D., Caskey, F. J. & Ben-Shlomo, Y., 2021, In: Clinical Journal Of The American Society Of Nephrology. 16, 2, p. 194-203 10 p.

    Research output: Contribution to journalArticlepeer-review

  10. Hemodiafiltration Is Associated With Reduced Inflammation and Increased Bone Formation Compared With Conventional Hemodialysis in Children: The HDF, Hearts and Heights (3H) Study

    Fischer, D. C., Smith, C., De Zan, F., Bacchetta, J., Bakkaloglu, S. A., Agbas, A., Anarat, A., Aoun, B., Askiti, V., Azukaitis, K., Bayazit, A., Bulut, I. K., Canpolat, N., Borzych-Dużałka, D., Duzova, A., Habbig, S., Krid, S., Licht, C., Litwin, M., Obrycki, L., & 14 othersPaglialonga, F., Rahn, A., Ranchin, B., Samaille, C., Shenoy, M., Sinha, M. D., Spasojevic, B., Stefanidis, C. J., Vidal, E., Yilmaz, A., Fischbach, M., Schaefer, F., Schmitt, C. P. & Shroff, R., 2021, (Accepted/In press) In: Kidney International Reports.

    Research output: Contribution to journalArticlepeer-review

  11. Identifying Isolated Systolic Hypertension from Upper-Arm Cuff Blood Pressure Compared with Invasive Measurements

    Picone, D. S., Schultz, M. G., Armstrong, M. K., Black, J. A., Bos, W. J. W., Chen, C. H., Cheng, H. M., Cremer, A., Dwyer, N., Hughes, A. D., Kim, H. L., Lacy, P. S., Laugesen, E., Liang, F., Ohte, N., Okada, S., Omboni, S., Ott, C., Pereira, T., Pucci, G., & 10 othersSchmieder, R. E., Sinha, M. D., Stouffer, G. A., Takazawa, K., Roberts-Thomson, P., Wang, J. G., Weber, T., Westerhof, B. E., Williams, B. & Sharman, J. E., 2021, (Accepted/In press) In: Hypertension. p. 632-639 8 p.

    Research output: Contribution to journalArticlepeer-review

  12. Associations with kidney transplant survival and eGFR decline in children and young adults in the United Kingdom: a retrospective cohort study

    Hamilton, A. J., Plumb, L. A., Casula, A. & Sinha, M. D., Dec 2020, In: BMC Nephrology. 21, 1, 492.

    Research output: Contribution to journalArticlepeer-review

  13. The incidence of and risk factors for late presentation of childhood chronic kidney disease: A systematic review and meta-analysis

    Plumb, L., Boother, E. J., Caskey, F. J., Sinha, M. D. & Ben-Shlomo, Y., Dec 2020, In: PLoS ONE. 15, 12 December, e0244709.

    Research output: Contribution to journalReview articlepeer-review

  14. Haemodynamics of Hypertension in Children

    Li, Y., Haseler, E., Chowienczyk, P. & Sinha, M. D., 1 Aug 2020, In: CURRENT HYPERTENSION REPORTS. 22, 8, 60.

    Research output: Contribution to journalReview articlepeer-review

  15. Vitamin and trace element concentrations in infants and children with chronic kidney disease

    Joyce, T., Rasmussen, P., Melhem, N., Clothier, J., Booth, C. & Sinha, M. D., 1 Aug 2020, In: Pediatric Nephrology. 35, 8, p. 1463-1470 8 p.

    Research output: Contribution to journalArticlepeer-review

  16. Hemodynamic Characterization of Primary Hypertension in Children and Adolescents

    Li, Y., Gu, H., Sinha, M. D. & Chowienczyk, P., 16 Jun 2020, In: Journal of the American Heart Association. 9, 12, p. e015097

    Research output: Contribution to journalArticlepeer-review

  17. Cardiac Function in Young Patients with Elevated Blood Pressure

    Simpson, J. M. & Sinha, M. D., 1 Jun 2020, In: Hypertension. 75, 6, p. 1417-1418 2 p.

    Research output: Contribution to journalEditorialpeer-review

  18. The Incidence of Paediatric Acute Kidney Injury Identified Using an AKI E-Alert Algorithm in Six English Hospitals

    British Association for Paediatric Nephrology, 11 Feb 2020, In: Frontiers in Pediatrics. 8, 29.

    Research output: Contribution to journalArticlepeer-review

  19. Renal replacement therapy and conservative management: NICE guideline (NG 107) October 2018

    Arslan, Z., Khurram, M. A. & Sinha, M. D., 1 Jan 2020, (Accepted/In press) In: Archives of Disease in Childhood: Education and Practice Edition.

    Research output: Contribution to journalReview articlepeer-review

  20. UK national study of barriers to renal transplantation in children

    Kim, J. S., Marlais, M., Balasubramanian, R., Muorah, M., Inward, C., Smith, G. C., Reynolds, B. C., Yadav, P., Morgan, H., Shenoy, M., Tse, Y., Hussain, F., Grylls, S., Kessaris, N., Sinha, M. D. & Marks, S. D., 1 Jan 2020, (Accepted/In press) In: Archives of Disease in Childhood. 318272.

    Research output: Contribution to journalArticlepeer-review

  21. Acute kidney injury in children with chronic kidney disease is associated with faster decline in kidney function

    Melhem, N., Rasmussen, P., Joyce, T., Clothier, J., Reid, C. J. D., Booth, C. & Sinha, M. D., 2020, (Accepted/In press) In: Pediatric Nephrology.

    Research output: Contribution to journalArticlepeer-review

  22. Silent and dangerous: catheter-associated right atrial thrombus (CRAT) in children on chronic haemodialysis

    Garcia-Nicoletti, M., Sinha, M. D., Savis, A., Adalat, S., Karunanithy, N. & Calder, F., 2020, (Accepted/In press) In: Pediatric Nephrology.

    Research output: Contribution to journalArticlepeer-review

  23. International consensus statement on the diagnosis and management of autosomal dominant polycystic kidney disease in children and young people

    Gimpel, C., Bergmann, C., Bockenhauer, D., Breysem, L., Cadnapaphornchai, M. A., Cetiner, M., Dudley, J., Emma, F., Konrad, M., Harris, T., Harris, P. C., König, J., Liebau, M. C., Marlais, M., Mekahli, D., Metcalfe, A. M., Oh, J., Perrone, R. D., Sinha, M. D., Titieni, A., & 4 othersTorra, R., Weber, S., Winyard, P. J. D. & Schaefer, F., 1 Nov 2019, In: Nature Reviews Nephrology. 15, 11, p. 713-726 14 p.

    Research output: Contribution to journalReview articlepeer-review

  24. Central blood pressure and measures of early vascular disease in children with ADPKD

    Marlais, M., Rajalingam, S., Gu, H., Savis, A., Sinha, M. D. & Winyard, P. J., 1 Oct 2019, In: Pediatric Nephrology. 34, 10, p. 1791-1797 7 p.

    Research output: Contribution to journalArticlepeer-review

  25. Improved blood pressure and left ventricular remodelling in children on chronic intermittent haemodialysis: a longitudinal study

    Melhem, N., Savis, A., Wheatley, A., Copeman, H., Willmott, K., Reid, C. J. D., Simpson, J. & Sinha, M. D., 1 Oct 2019, In: Pediatric Nephrology. 34, 10, p. 1811-1820 10 p.

    Research output: Contribution to journalArticlepeer-review

  26. Renal disease in pregnancy: Fetal, neonatal and long-term outcomes

    Haseler, E., Melhem, N. & Sinha, M. D., 1 May 2019, In: Best Practice and Research: Clinical Obstetrics and Gynaecology. 57, p. 60-76 17 p.

    Research output: Contribution to journalReview articlepeer-review

  27. Effects of hemodiafiltration versus conventional hemodialysis in children with ESKD: The HDF, heart and height study

    Shroff, R., Smith, C., Ranchin, B., Bayazit, A. K., Stefanidis, C. J., Askiti, V., Azukaitis, K., Canpolat, N., Agba, A., Aitkenhead, H., Anarat, A., Aoun, B., Aofolaju, D., Bakkaloglu, S. A., Bhowruth, D., Borzych-Duza, D., Bulut, I. K., Büscher, R., Deanfield, J., Dempster, C., & 25 othersDuzova, A., Habbig, S., Hayes, W., Hegde, S., Krid, S., Licht, C., Litwin, M., Mayes, M., Mir, S., Nemec, R., Obrycki, L., Paglialonga, F., Picca, S., Samaille, C., Shenoy, M., Sinha, M. D., Spasojevic, B., Stronach, L., Vidal, E., Vondrák, K., Yilmaz, A., Zaloszyc, A., Fischbach, M., Schmitt, C. P. & Schaefer, F., 1 Apr 2019, In: Journal of the American Society of Nephrology. 30, 4, p. 678-691 14 p.

    Research output: Contribution to journalArticlepeer-review

  28. Vitamin B6 blood concentrations in paediatric dialysis patients

    Joyce, T., Brown, F. C., Adalat, S., Reid, C. J. D. & Sinha, M. D., 1 Nov 2018, In: Pediatric Nephrology. 33, 11, p. 2161-2165 5 p.

    Research output: Contribution to journalArticlepeer-review

  29. Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management

    Bierzynska, A., McCarthy, H. J., Soderquest, K., Sen, E. S., Colby, E., Ding, W. Y., Nabhan, M. M., Kerecuk, L., Hegde, S., Hughes, D., Marks, S., Feather, S., Jones, C., Webb, N. J. A., Ognjanovic, M., Christian, M., Gilbert, R. D., Sinha, M. D., Lord, G. M., Simpson, M., & 3 othersKoziell, A. B., Welsh, G. I. & Saleem, M. A., 20 Jan 2017, In: Kidney International.

    Research output: Contribution to journalArticlepeer-review

  30. Fifteen-minute consultation: The child with systemic arterial hypertension

    Singh, C., Jones, H., Copeman, H. & Sinha, M. D., 2017, In: Archives of Disease in Childhood: Education and Practice Edition. 102, 1, p. 2-7 6 p.

    Research output: Contribution to journalArticlepeer-review

  31. Biomarkers of tolerance in kidney transplantation – are we predicting tolerance or response to immunosuppressive treatment?

    Rebollo-Mesa, I., Nova-Lamperti, E., Mobillo, P., Runglall, M., Christakoudi, S., Norris, S., Smallcombe, N., Kamra, Y., Hilton, R., Consortium, I. O. T. EU., Bhandari, S., Baker, R., Berglund, D., Carr, S., Game, D., Griffin, S., Kalra, P. A., Lewis, R., Mark, P. B., Marks, S., & 12 othersMacphee, I., McKane, W., Mohaupt, M. G., Pararajasingam, R., Kon, S. P., Serón, D., Sinha, M., Tucker, B., Viklický, O., Lechler, R. I., Lord, G. M. & Hernandez-Fuentes, M. P., 21 Jun 2016, (E-pub ahead of print) In: American Journal of Transplantation.

    Research output: Contribution to journalArticlepeer-review

  32. Relationship of FGF23 to indexed left ventricular mass in children with non-dialysis stages of chronic kidney disease

    Sinha, M. D., Turner, C., Booth, C. J., Waller, S., Rasmussen, P., Goldsmith, D. J. A. & Simpson, J. M., 28 Oct 2015, In: Pediatric Nephrology. 30, 10, p. 1843-1852 10 p.

    Research output: Contribution to journalArticlepeer-review

  33. Elevated Myocardial Wall Stress in Children with Chronic Kidney Disease

    Gu, H., Sinha, M. D., Li, Y., Simpson, J. & Chowienczyk, P. J., 31 Aug 2015, (E-pub ahead of print) In: Hypertension. 15 p.

    Research output: Contribution to journalArticlepeer-review

  34. Central aortic blood pressure from ultrasound wall-tracking of the carotid artery in children: Comparison with invasive measurements and radial tonometry

    Milne, L., Keehn, L., Guilcher, A., Reidy, J. F., Karunanithy, N., Rosenthal, E., Qureshi, S., Chowienczyk, P. J. & Sinha, M. D., 21 May 2015, In: Hypertension. 65, 5, p. 1141-1146 6 p.

    Research output: Contribution to journalArticlepeer-review

  35. Response to Validation of Devices and Methods for Noninvasive Estimation of Central Aortic Blood Pressure in Children

    Milne, L., Keehn, L., Guilcher, A., Reidy, J. F., Karunanithy, N., Rosenthal, E., Qureshi, S., Chowienczyk, P. J. & Sinha, M. D., 1 Jan 2015, In: Hypertension. 66, 2, p. e8

    Research output: Contribution to journalLetterpeer-review

  36. UK Renal Registry 16th Annual Report: Chapter 13 Clinical, Haematological and Biochemical Parameters in Patients Receiving Renal Replacement Therapy in Paediatric Centres in the UK in 2012: National and Centre-specific Analyses

    Pruthi, R., Maxwell, H., Casula, A., Braddon, F., Lewis, M., O'Brien, C., Stojanovic, J., Tse, Y., Inward, C. & Sinha, M., Feb 2014, In: NEPHRON CLINICAL PRACTICE. 125, 1-4, p. 259-273 15 p.

    Research output: Contribution to journalArticlepeer-review

  37. UK Renal Registry 16th Annual Report: Chapter 7 Demography of the UK Paediatric Renal Replacement Therapy population in 2012

    Pruthi, R., O'Brien, C., Casula, A., Braddon, F., Lewis, M., Maxwell, H., Stojanovic, J., Tse, Y., Inward, C. & Sinha, M. D., Feb 2014, In: NEPHRON CLINICAL PRACTICE. 125, 1-4, p. 127-138 12 p.

    Research output: Contribution to journalArticlepeer-review

  38. Longitudinal changes in body mass index following renal transplantation in UK children

    Plumb, L. A., Pitcher, D., Tse, Y., Shield, J. P., Inward, C., Sinha, M. & British Assoc Paediat Nephrology, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 196-203 8 p.

    Research output: Contribution to journalArticlepeer-review

  39. FGF23 concentrations measured using "intact" assays similar but not interchangeable

    Sinha, M., Turner, C. & Goldsmith, D., Dec 2013, In: International Urology and Nephrology. 45, 6, p. 1821-1823 3 p.

    Research output: Contribution to journalLetterpeer-review

  40. Underweight, overweight and obesity in paediatric dialysis and renal transplant patients

    Bonthuis, M., van Stralen, K. J., Verrina, E., Groothoff, J. W., Alonso Melgar, A., Edefonti, A., Fischbach, M., Mendes, P., Molchanova, E. A., Paripovic, D., Peco-Antic, A., Printza, N., Rees, L., Rubik, J., Stefanidis, C. J., Sinha, M., Zagozdzon, I., Jager, K. J. & Schaefer, F., Nov 2013, In: Nephrology, Dialysis, Transplantation. 28, suppl 4, p. 195-204 10 p.

    Research output: Contribution to journalArticlepeer-review

  41. Intracranial hypertension presenting with severe visual failure, without concurrent headache, in a child with nephrotic syndrome

    Barnett, M., Sinha, M., Morrison, D. & Lim, M., 10 Oct 2013, In: BMC Pediatrics . 13, 4 p., 167.

    Research output: Contribution to journalArticlepeer-review

  42. UK Renal Registry 15th Annual Report: Chapter 4: Demography of the UK Paediatric Renal Replacement Therapy Population in 2011

    Pruthi, R., O'Brien, C., Casula, A., Braddon, F., Lewis, M., Maxwell, H., Tse, Y., Inward, C. & Sinha, M., Jun 2013, In: NEPHRON CLINICAL PRACTICE. 123, Suppl. 1, p. 81-92 12 p.

    Research output: Contribution to journalArticlepeer-review

  43. UK Renal Registry 15th Annual Report: Chapter 7 Clinical, Haematological and Biochemical Parameters in Patients Receiving Renal Replacement Therapy in Paediatric Centres in the UK in 2011: National and Centre-Specific Analyses

    Pruthi, R., Maxwell, H., Casula, A., Braddon, F., Lewis, M., O'Brien, C., Tse, Y., Inward, C. & Sinha, M., Jun 2013, In: NEPHRON CLINICAL PRACTICE. 123, Suppl. 1, p. 151-164 14 p.

    Research output: Contribution to journalArticlepeer-review

  44. Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome

    McCarthy, H. J., Bierzynska, A., Wherlock, M., Ognjanovic, M., Kerecuk, L., Hegde, S., Feather, S., Gilbert, R. D., Krischock, L., Jones, C., Sinha, M. D., Webb, N. J. A., Christian, M., Williams, M. M., Marks, S., Koziell, A., Welsh, G. I., Saleem, M. A. & RADAR the UK SRNS Study Group, Apr 2013, In: Clinical Journal Of The American Society Of Nephrology. 8, 4, p. 637-48 12 p.

    Research output: Contribution to journalArticlepeer-review

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