Mano Runglall

2022

Pretransplant FLT3-ITD MRD assessed by high-sensitivity PCR-NGS determines posttransplant clinical outcome

Loo, S., Dillon, R., Ivey, A., Anstee, N. S., Othman, J., Tiong, I. S., Potter, N., Jovanovic, J., Runglall, M., Chong, C. C., Bajel, A., Ritchie, D., Gray, K., Yeoh, Z. H., McBean, M., Gilkes, A., Thomas, I., Johnson, S., Russell, N. H. & Wei, A. H., 1 Dec 2022, In: Blood. 140, 22, p. 2407-2411 5 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

34 Citations (Scopus)

2021

Patients with triple-negative, JAK2V617F- and CALR-mutated essential thrombocythemia share a unique gene expression signature

Alimam, S., Villiers, W., Dillon, R., Simpson, M., Runglall, M., Smith, A., Chatzikyriakou, P., Lavender, P., Kanda, A., Mills, K., Bellosillo Paricio, B., Kaufman-Cook, J., Ord, S., Kordasti, S., Radia, D., Woodley, C., Francis, Y., Mufti, G., McLornan, D. P. & Harrison, C. N., 23 Feb 2021, In: Blood Advances. 5, 4, p. 1059-1068 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Citations (Scopus)

2020

Development and validation of the first consensus gene-expression signature of operational tolerance in kidney transplantation, incorporating adjustment for immunosuppressive drug therapy

Christakoudi, S., Runglall, M., Mobillo, P., Rebollo-Mesa, I., Tjir-Li, T., Viklický, O., Stahl, D., Lechler, R., Lord, G. & Hernandez Fuentes, M., 1 Aug 2020, In: EBioMedicine. 58, 102899.

Research output: Contribution to journal › Article › peer-review

Open Access

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16 Citations (Scopus)

93 Downloads (Pure)

Molecular MRD status and outcome after transplantation in NPM1 mutated AML

Dillon, R., Hills, R. K., Freeman, S. D., Potter, N., Jovanovic, J., Ivey, A., Kanda, A., Runglall, M., Foot, N., Valganon, M., Khwaja, A., Cavenagh, J., Smith, M. L., Ommen, H. B., Overgaard, U., Dennis, M., Knapper, S., Kaur, H., Taussig, D. C., Mehta, P., & 19 othersRaj, K., Novitzky-Basso, I., Nikolousis, E., Danby, R. D., Krishnamurthy, P., Hill, K., Finnegan, D., Alimam, S., Hurst, E., Johnson, P., Khan, A. B., Salim, R., Craddock, C. F., Spearing, R. L., Gilkes, A. F., Gale, R. E., Burnett, A. K., Russell, N. H. & Grimwade, D., 27 Feb 2020, In: Blood. 135, 9, p. 680-688 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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114 Citations (Scopus)

113 Downloads (Pure)

Venetoclax induces rapid elimination of NPM1 mutant measurable residual disease in combination with low-intensity chemotherapy in acute myeloid leukaemia

Tiong, I. S., Dillon, R., Ivey, A., Teh, T-C., Nguyen, P., Cummings, N., Taussig, D. C., Latif, A-L., Potter, N. E., Runglall, M., Russell, N. H., Raj, K., Schwarer, A. P., Fong, C. Y., Grigg, A. P. & Wei, A. H., 26 May 2020, (E-pub ahead of print) In: British Journal of Haematology.

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

2019

Development of a multivariable geneexpression signature targeting T-cell-mediated rejection in peripheral blood of kidney transplant recipients validated in crosssectional and longitudinal samples

Christakoudi, S., Runglall, M., Mobillo, P. A., Tsui, T-L., Duff, C., Domingo Vila, C., Kamra, Y. K., Delaney, F., Montero, R., Spiridou, A., Kassimatis, T., Phin Kon, S., Tucker, B., Farmer, C., Strom, T. B., Lord, G. M., Rebollo-Mesa, I., Stahl, D., Sacks, S., Hernandez-Fuentes, M. P., & 1 othersChowdhury, P., 1 Mar 2019, In: EBioMedicine. 41, 0, p. 571-583 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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27 Citations (Scopus)

99 Downloads (Pure)

Gene expression biomarkers for kidney transplant rejection-The entire landscape–Author's reply

Christakoudi, S., Runglall, M., Chowdhury, P. & Hernandez-Fuentes, M., 1 Apr 2019, In: EBioMedicine. 42, 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

2018

Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation

Christakoudi, S., Runglall, M., Mobillo, P., Rebollo-Mesa, I., Tsui, T-L., Nova-Lamperti, E., Norris, S., Kamra, Y., Hilton, R., Bhandari, S., Baker, R., Berglund, D., Carr, S., Game, D., Griffin, S., Kalra, P. A., Lewis, R., Mark, P. B., Marks, S. D., Macphee, I., & 12 othersMcKane, W., Mohaupt, M. G., Pararajasingam, R., Kon, S. P., Serón, D., Sinha, M., Tucker, B., Viklický, O., Lechler, R. I., Lord, G. M., Stahl, D. & Hernandez-Fuentes, M. P., 15 Sept 2018, In: Molecular and Cellular Endocrinology. 473, p. 205-216 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (Scopus)

2017

Reduced TCR-signalling contributes to impaired Th17 responses in tolerant kidney transplant recipients

Nova-Lamperti, E., Romano, M., Christakoudi, S., Runglall, M., McGregor, R., Mobillo, P., Kamra, Y., Tsui, T-L., Norris, S., John, S., Boardman, D. A., Lechler, R. I., Lombardi, G., Hernandez-Fuentes, M. P. & www.GAMBITstudy.co.uk, 12 Sept 2017, (E-pub ahead of print) In: Transplantation.

Research output: Contribution to journal › Article › peer-review

Open Access

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10 Citations (Scopus)

208 Downloads (Pure)

2016

Biomarkers of tolerance in kidney transplantation – are we predicting tolerance or response to immunosuppressive treatment?

Rebollo-Mesa, I., Nova-Lamperti, E., Mobillo, P., Runglall, M., Christakoudi, S., Norris, S., Smallcombe, N., Kamra, Y., Hilton, R., Consortium, I. O. T. EU., Bhandari, S., Baker, R., Berglund, D., Carr, S., Game, D., Griffin, S., Kalra, P. A., Lewis, R., Mark, P. B., Marks, S., & 12 othersMacphee, I., McKane, W., Mohaupt, M. G., Pararajasingam, R., Kon, S. P., Serón, D., Sinha, M., Tucker, B., Viklický, O., Lechler, R. I., Lord, G. M. & Hernandez-Fuentes, M. P., 21 Jun 2016, (E-pub ahead of print) In: American Journal of Transplantation.

Research output: Contribution to journal › Article › peer-review

Open Access

File

88 Citations (Scopus)

207 Downloads (Pure)

Candidalysin is a fungal peptide toxin critical for mucosal infection

Moyes, D. L., Wilson, D., Richardson, J. P., Mogavero, S., Tang, S. X., Wernecke, J., Hofs, S., Gratacap, R. L., Robbins, J., Runglall, M., Murciano, C., Blagojevic, M., Thavaraj, S., Forster, T. M., Hebecker, B., Kasper, L., Vizcay-Barrena, G., Iancu, S. I., Kichik, N., Hader, A., & 11 othersKurzai, O., Luo, T., Kruger, T., Kniemeyer, O., Cota, E., Bader, O., Bader, O., Wheeler, R. T., Gutsmann, T., Hube, B. & Naglik, J. R., 7 Apr 2016, In: NATURE. 532, 7597, p. 64-68 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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619 Citations (Scopus)

273 Downloads (Pure)

Increased CD40 ligation and reduced BCR signalling leads to higher IL-10 production in B-cells from tolerant kidney transplant patients

www.GAMBITstudy.co.uk, Lord, G. M., Lechler, R. I. & Lombardi, G., 28 Jul 2016, In: Transplantation. TPA-2016-0165R1 .

Research output: Contribution to journal › Article › peer-review

Open Access

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31 Citations (Scopus)

174 Downloads (Pure)

2014

2014 British Transplant Society Conference (Oral)

Runglall, M., Rebollo-Mesa, I., Kamra, Y., Mobillo, P., Duff, C., Lo, J., Jenkins, M., Beswick, L., Willis, J., Phin Kon, S., Tucker, B., Farmer, C., Strom, T., Lord, G., Sacks, S., Hernandez Fuentes, M. & Chowdhury, P., Feb 2014, 2014 British Transplant Society Conference .

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract

A Multiplatform Biomarker Signature Of Acute Rejection In Renal Allograft Recipients

Merritt, E., Perucha, E., Runglall, M., Rebollo-Mesa, I., Kamra, Y., Mobillo, P., Phin Kon, S., Tucker, B., Farmer, C., Inokuma, M., Heck, S., Strom, T., Sacks, S., Chowdhury, P., Lord, G. & Hernandez Fuentes, M., Feb 2014, 2014 British Transplant Society Conference . British Transplantation Society, P103

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

FRA2 Is a STAT5 Target Gene Regulated by IL-2 in Human CD4 T Cells

Rani, A., Greenlaw, R., Runglall, M., Jurcevic, S. & John, S., 28 Feb 2014, In: PLoS ONE. 9, 2, p. N/A 9 p., e90370.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (Scopus)

Protection Against Epithelial Damage During Candida albicans Infection Is Mediated by PI3K/Akt and Mammalian Target of Rapamycin Signaling

Moyes, D., Shen, C., Murciano, C., Runglall, M., Richardson, J., Arno, M., Aldecoa-Otalora, E. & Naglik, J., 1 Jun 2014, In: Journal of Infectious Diseases. 209, 11, p. 1816–1826 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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70 Citations (Scopus)

69 Downloads (Pure)

Steroid Withdrawal Normalises The Proportion Of Transitional B Cells But Does Not Significantly Change Gene Expression In Renal Transplant Recipients

Runglall, M. & Hernandez Fuentes, M., Feb 2014, 2014 British Transplant Society Conference. British Transplantation Society, P104

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract

2013

Runglall, M., Rebollo-Mesa, I., Kamra, Y., Lo, J., Jenkins, M., Beswick, L., Willis, J., Phin Kon, S., Tucker, B., Farmer, C., Strom, T., Lord, G., Sacks, S., Hernandez Fuentes, M. & Chowdhury, P., Apr 2013, 2013 The 4th International Conference on Transplantomics and Biomarkers in Organ Transplantation.

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

2013 The British Society for Immunology Congress

Smallcombe, N., Nova Lamperti, E., Mobillo, P., Rebollo-Mesa, I., Runglall, M., Kamra, Y., Norris, S., Razae, S., Lombardi, G., Lord, G., Lechler, R., Hernandez Fuentes, M. & Consortium, G. A. M. B. I. T., Dec 2013, 2013 The British Society for Immunology Congress .

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

Corticosteroid withdrawal normalises the proportion of transitional B cells but does not significantly change gene expression in renal transplant recipients

Smallcombe, N., Nova-Lamperti, E., Mobillo, P., Rebollo-Mesa, I., Runglall, M., Kamra, Y., Norris, S., Rezae, S., Hilton, R. & Lombardi, G., Dec 2013, In: Immunology. 140, p. 62-62 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Messenger RNA Levels in Non-invasive Samples Can Potentially Stratify Risk of Rejection in Renal Transplant Recipients

Runglall, M., Rebollo-Mesa, I., Kamra, Y., Phin Kon, S., Tucker, B., Farmer, C., Strom, T., Lord, G., Sacks, S., Hernandez Fuentes, M. & Chowdhury, P., May 2013, 2013 American Transplant Congress .

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

Messenger RNA Levels in Non-Invasive Samples Can Potentially Stratify Risk of Rejection in Renal Transplant Recipients

Runglall, M., Rebollo-Mesa, I., Kamra, Y., Kon, S. P., Tucker, B., Farmer, C., Strom, T., Lord, G., Sacks, S., Hernandez-Fuentes, M. & Chowdhury, P., Apr 2013, In: American Journal of Transplantation. 13, p. 233-233 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Open Access

Three-gene signature of tolerance for clinical application in kidney transplant recipients

Rebollo-Mesa, I., Mobillo, P., Nova Lamperti, E., Norris, S., Kamra, Y., Runglall, M., Consortium, G. A. M. B. I. T., ITN, I. T. N., Consortium, I. O. T., Lord, G., Lechler, R. & Hernandez Fuentes, M., May 2013, 2013 American Transplant Congress .

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

Three-Gene Signature of Tolerance for Clinical Application in Kidney Transplant Recipients

Rebollo-Mesa, I., Mobillo, P., Nova-Lamperti, E., Norris, S., Kamra, Y., Runglall, M., Lord, G., Lechler, R., Hernandez-Fuentes, M., GAMBIT Consortium, Immune Tolerance Network & Indices Tolerance Consortium, Apr 2013, In: American Journal of Transplantation. 13, p. 102-102 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Tolerance Related Gene Expression in Urine from Kidney Transplant Recipients

Jenkins, M., Runglall, M., Rebollo-Mesa, I., Mobillo, P., Kamra, Y., Nova Lamperti, E., Norris, S., Consortium, G. A. M. B. I. T., Lord, G., Lechler, R. & Hernandez Fuentes, M., May 2013, 2013 American Transplant Congress .

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

Tolerance Related Gene Expression in Urine from Kidney Transplant Recipients

Jenkins, M., Runglall, M., Rebollo-Mesa, I., Mobillo, P., Kamra, Y., Nova-Lamperti, E., Norris, S., Consortium, G. A. M. B. I. T., Lord, G., Lechler, R. & Hernandez-Fuentes, M., Apr 2013, In: American Journal of Transplantation. 13, p. 367-368 2 p., B1135.

Research output: Contribution to journal › Conference paper › peer-review

2012

Chowdhury, P., Rebollo-Mesa, I., Runglall, M., Mobillo, P., Norris, S., Phin Kon, S., Tucker, B., Farmer, C., Lord, G., Strom, T., Sacks, S. & Hernandez Fuentes, M., Mar 2012, 2012 The 3rd International Conference on Transplantomics and Biomarkers in Organ Transplantation.

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

Activation of MAPK/c-Fos induced responses in oral epithelial cells is specific to Candida albicans and Candida dubliniensis hyphae

Moyes, D. L., Murciano, C., Runglall, M., Kohli, A., Islam, A. & Naglik, J. R., Feb 2012, In: Medical Microbiology and Immunology. 201, 1, p. 93 - 101 9 p.

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

A Validated RT-PCR Based Gene Signature for Tolerance in Kidney Transplant Recipients

Rebollo-Mesa, I., Norris, S., Nova Lamperti, E., Mobillo, P., Runglall, M., Kamra, Y., Perucha, E., Lord, G., Lechler, R. & Hernandez Fuentes, M., Jul 2012, 2012 The 24th INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY.

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

Evaluation of the Role of Candida albicans Agglutinin-Like Sequence (Als) Proteins in Human Oral Epithelial Cell Interactions

Murciano, C., Moyes, D., Runglall, M., Tobouti, P., Islam, A., Hoyer, L. L. & Naglik, J., 12 Mar 2012, In: PloS one. 7, 3, 9 p., e33362.

Research output: Contribution to journal › Article › peer-review

Open Access

File

93 Citations (Scopus)

165 Downloads (Pure)

From Bench to Clinic: Translating Biomarkers of Tolerance in Renal Allograft Recipients

Norris, S., Nova Lamperti, E., Mobillo, P., Kamra, Y., Runglall, M., Rebollo-Mesa, I., Lord, G., Lechler, R. & Hernandez Fuentes, M., Jul 2012, 2012 The 24th INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY.

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

Messenger RNA Levels in Peripheral Blood and Urine Can Potentially Stratify Risk of Rejection Following Renal Transplantation

Runglall, M., Rebollo-Mesa, I., Mobillo, P., Norris, S., Phin Kon, S., Tucker, B., Farmer, C., Lord, G., Storm, T., Sacks, S., Hernandez Fuentes, M. & Chowdhury, P., Jul 2012, 2012 The 24th INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY.

Research output: Chapter in Book/Report/Conference proceeding › Poster abstract

2011

Candida albicans cell wall glycosylation may be indirectly required for activation of epithelial cell proinflammatory responses

Murciano, C., Moyes, D. L., Runglall, M., Islam, A., Mille, C., Fradin, C., Poulain, D., Gow, N. A. R. & Naglik, J. R., Dec 2011, In: Infection and Immunity. 79, 12, p. 4902-4911 10 p.

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Candida albicans yeast and hyphae are discriminated by MAPK signaling in vaginal epithelial cells

Moyes, D. L., Murciano, C., Runglall, M., Islam, A., Thavaraj, S. & Naglik, J. R., 8 Nov 2011, In: PL o S One . 6, 11, p. e26580 e26580.

Research output: Contribution to journal › Article › peer-review

93 Citations (Scopus)

2010

Activation of AKT but not NFAT or JAK/STAT signaling by Candida albicans infection of oral epithelial cells

Moyes, D. L., Runglall, M., Murciano, C., Shen, C. & Naglik, J. R., 2010, In: Immunology. 131, p. 166 - 167 2 p.

Research output: Contribution to journal › Meeting abstract

Epithelial cell discriminates between commensal and pathogenic Candida albicans via MAPK signaling independently of Dectin1, TLR2 or TLR4

Moyes, D. L., Runglall, M., Murciano, C., Challacombe, S. J. & Naglik, J. R., 2010, In: Immunology. 131, p. 166 - 166 1 p.

Research output: Contribution to journal › Meeting abstract

Mano Runglall

Research output

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