King's College London

Research portal

Manu Shankar-Hari

  1. Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis

    WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, 6 Jul 2021, In: JAMA.

    Research output: Contribution to journalArticlepeer-review

  2. Impact of differences in acute respiratory distress syndrome randomised controlled trial inclusion and exclusion criteria: systematic review and meta-analysis

    Saha, R., Assouline, B., Mason, G., Douiri, A., Summers, C. & Shankar-Hari, M., Jul 2021, In: British Journal of Anaesthesia. 127, 1, p. 85-101 17 p.

    Research output: Contribution to journalReview articlepeer-review

  3. The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

    Osuchowski, M. F., Winkler, M. S., Skirecki, T., Cajander, S., Shankar-Hari, M., Lachmann, G., Monneret, G., Venet, F., Bauer, M., Brunkhorst, F. M., Weis, S., Garcia-Salido, A., Kox, M., Cavaillon, J-M., Uhle, F., Weigand, M. A., Flohé, S. B., Wiersinga, W. J., Almansa, R., de la Fuente, A. & 14 others, Martin-Loeches, I., Meisel, C., Spinetti, T., Schefold, J. C., Cilloniz, C., Torres, A., Giamarellos-Bourboulis, E. J., Ferrer, R., Girardis, M., Cossarizza, A., Netea, M. G., van der Poll, T., Bermejo-Martín, J. F. & Rubio, I., Jun 2021, In: The Lancet Respiratory Medicine. 9, 6, p. 622-642 21 p.

    Research output: Contribution to journalReview articlepeer-review

  4. Virological and serological characterization of critically ill patients with COVID-19 in the UK: Interactions of viral load, antibody status and B.1.1.7 variant infection

    Ratcliff, J., Nguyen, D., Fish, M., Rynne, J., Jennings, A., Williams, S., Al-Beidh, F., Bonsall, D., Evans, A., Golubchik, T., Gordon, A. C., Lamikanra, A., Tsang, P., Ciccone, N. A., Leuscher, U., Slack, W., Laing, E., Mouncey, P. R., Ziyenge, S., Oliveira, M. & 8 others, Ploeg, R., Rowan, K. M., Shankar-Hari, M., Roberts, D. J., Menon, D. K., Estcourt, L., Simmonds, P. & Harvala, H., 24 May 2021, In: The Journal of infectious diseases.

    Research output: Contribution to journalArticlepeer-review

  5. Changes in temperature management and outcome after out-of-hospital cardiac arrest in United Kingdom intensive care units following publication of the Targeted Temperature Management trial

    Nolan, J. P., Orzechowska, I., Harrison, D. A., Soar, J., Perkins, G. D. & Shankar-Hari, M., May 2021, In: Resuscitation. 162, p. 304-311 8 p.

    Research output: Contribution to journalArticlepeer-review

  6. Immunological subpopulations within critically ill COVID-19 patients

    Wilson, J. & Shankar-Hari, M., May 2021, In: Chest. 159, 5, p. 1706-1708 3 p.

    Research output: Contribution to journalEditorialpeer-review

  7. Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

    REMAP-CAP Investigators, 22 Apr 2021, In: New England Journal of Medicine. 384, 16, p. 1491-1502 12 p.

    Research output: Contribution to journalArticlepeer-review

  8. Utilising mass cytometry with CD45 barcoding and standardised leucocyte phenotyping for immune trajectory assessment in critically ill patients

    Fish, M., Ellis, R., Bishop, C., Todd, K., Petrov, N., Singer, M., Swanson, C. M. & Shankar-Hari, M., Apr 2021, In: British Journal of Anaesthesia. 126, 4, p. e149-e152

    Research output: Contribution to journalLetterpeer-review

  9. Precision medicine in acute respiratory distress syndrome: workshop report and recommendations for future research

    Bos, L. D. J., Artigas, A., Constantin, J-M., Hagens, L. A., Heijnen, N., Laffey, J. G., Meyer, N., Papazian, L., Pisani, L., Schultz, M. J., Shankar-Hari, M., Smit, M. R., Summers, C., Ware, L. B., Scala, R. & Calfee, C. S., 31 Mar 2021, In: European Respiratory Review. 30, 159, p. 1-11 11 p., 200317.

    Research output: Contribution to journalArticlepeer-review

  10. Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method

    Nasa, P., Azoulay, E., Khanna, A. K., Jain, R., Gupta, S., Javeri, Y., Juneja, D., Rangappa, P., Sundararajan, K., Alhazzani, W., Antonelli, M., Arabi, Y. M., Bakker, J., Brochard, L. J., Deane, A. M., Du, B., Einav, S., Esteban, A., Gajic, O., Galvagno, S. M. & 29 others, Guérin, C., Jaber, S., Khilnani, G. C., Koh, Y., Lascarrou, J-B., Machado, F. R., Malbrain, M. L. N. G., Mancebo, J., McCurdy, M. T., McGrath, B. A., Mehta, S., Mekontso-Dessap, A., Mer, M., Nurok, M., Park, P. K., Pelosi, P., Peter, J. V., Phua, J., Pilcher, D. V., Piquilloud, L., Schellongowski, P., Schultz, M. J., Shankar-Hari, M., Singh, S., Sorbello, M., Tiruvoipati, R., Udy, A. A., Welte, T. & Myatra, S. N., 16 Mar 2021, In: Critical care (London, England). 25, 1, p. 106 1 p., 106.

    Research output: Contribution to journalArticlepeer-review

  11. Sepsis Subclasses: A Framework for Development and Interpretation

    DeMerle, K. M., Angus, D. C., Baillie, J. K., Brant, E., Calfee, C. S., Carcillo, J., Chang, C-C. H., Dickson, R., Evans, I., Gordon, A. C., Kennedy, J., Knight, J. C., Lindsell, C. J., Liu, V., Marshall, J. C., Randolph, A. G., Scicluna, B. P., Shankar-Hari, M., Shapiro, N. I., Sweeney, T. E. & 10 others, Talisa, V. B., Tang, B., Thompson, B. T., Tsalik, E. L., van der Poll, T., van Vught, L. A., Wong, H. R., Yende, S., Zhao, H. & Seymour, C. W., 15 Feb 2021, In: Critical Care Medicine. p. 748-759 12 p.

    Research output: Contribution to journalArticlepeer-review

  12. Current Understanding of Leukocyte Phenotypic and Functional Modulation During Extracorporeal Membrane Oxygenation: A Narrative Review

    Ki, K. K., Millar, J. E., Langguth, D., Passmore, M. R., McDonald, C. I., Shekar, K., Shankar-Hari, M., Cho, H. J., Suen, J. Y. & Fraser, J. F., 8 Jan 2021, In: Frontiers in Immunology. 11, p. 600684 600684.

    Research output: Contribution to journalReview articlepeer-review

  13. Prognostic Factors for 30-Day Mortality in Critically Ill Patients With Coronavirus Disease 2019: An Observational Cohort Study

    ICNARC COVID-19 Team, 1 Jan 2021, In: Critical Care Medicine. 49, 1, p. 102-111 10 p.

    Research output: Contribution to journalArticlepeer-review

  14. Delirium in COVID-19: can we make the unknowns knowns?

    Wilcox, M. E., Shankar-Hari, M. & McAuley, D. F., 2021, (Accepted/In press) In: Intensive Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  15. Initial setting of high-flow nasal oxygen post extubation based on mean inspiratory flow during a spontaneous breathing trial

    Butt, S., Pistidda, L., Floris, L., Liperi, C., Vasques, F., Glover, G., Barrett, N. A., Sanderson, B., Grasso, S., Shankar-Hari, M. & Camporotaa, L., 27 Dec 2020, In: Journal of Critical Care. 63, p. 40-44 5 p.

    Research output: Contribution to journalArticlepeer-review

  16. Trends in Intensive Care for Patients with COVID-19 in England, Wales and Northern Ireland: American Journal of Respiratory and Critical Care Medicine

    Doidge, J. C., Gould, D. W., Ferrando-Vivas, P., Mouncey, P. R., Thomas, K., Shankar-Hari, M., Harrison, D. A. & Rowan, K. M., 12 Dec 2020, (Accepted/In press) In: American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  17. Genetic mechanisms of critical illness in Covid-19

    Pairo-Castineira, E., Clohisey, S., Klaric, L., Bretherick, A. D., Rawlik, K., Pasko, D., Walker, S., Parkinson, N., Fourman, M. H., Russell, C. D., Furniss, J., Richmond, A., Gountouna, E., Wrobel, N., Harrison, D., Wang, B., Wu, Y., Meynert, A., Griffiths, F., Oosthuyzen, W. & 248 others, Kousathanas, A., Moutsianas, L., Yang, Z., Zhai, R., Zheng, C., Grimes, G., Beale, R., Millar, J., Shih, B., Keating, S., Zechner, M., Haley, C., Porteous, D. J., Hayward, C., Yang, J., Knight, J., Summers, C., Shankar-Hari, M., Klenerman, P., Turtle, L., Ho, A., Moore, S. C., Hinds, C., Horby, P., Nichol, A., Maslove, D., Ling, L., McAuley, D., Montgomery, H., Walsh, T., Pereira, A., Renieri, A., Millar, J., Walsh, T., Openshaw, P. J. M., Ponting, C., Meikle, J., Finernan, P., Mcmaster, E., Law, A., Baillie, J. K., Paterson, T., Wackett, T., Armstrong, R., Clark, R., Coutts, A., Donnelly, L., Gilchrist, T., Hafezi, K., Macgillivray, L., Maclean, A., McCafferty, S., Morrice, K., Weaver, J., Boz, C., Golightly, A., Ward, M., Mal, H., Szoor-McElhinney, H., Brown, A., Hendry, R., Stenhouse, A., Cullum, L., Law, D., Law, S., Law, R., Swets, M., Day, N., Taneski, F., Duncan, E., Parkinson, N., Collier, D., Wood, S., Zak, A., Borra, C., Matharu, M., May, P., Alldis, Z., Mitchelmore, O., Bowles, R., Easthorpe, A., Bibi, F., Lancoma-Malcolm, I., Gurasashvili, J., Pheby, J., Shiel, J., Bolton, M., Patel, M., Taylor, M., Zongo, O., Ebano, P., Harding, P., Astin-Chamberlain, R., Choudhury, Y., Cox, A., Kallon, D., Burton, M., Hall, R., Blowes, S., Prime, Z., Biddle, J., Prysyazhna, O., Newman, T., Tierney, C., Kassam, J., Shankar-Hari, M., Ostermann, M., Campos, S., Bociek, A., Lim, R., Grau, N., Jones, T. O., Whitton, C., Marotti, M., Arbane, G., Bonner, S., Hugill, K., Welters, I., Waugh, V., Roman, J. F., Martinez, M. L., Waite, A., Hamilton, O., Mulla, S., McPhail, M., Smith, J., Baillie, J. K., Barclay, L., McCulloch, C., McQuillan, L., Singleton, J., Priestley, K., Rea, N., Callaghan, M., Andrew, G., Hutton, P., Bashyal, A., Davidson, N., Summers, C., Polgarova, P., Stroud, K., Pathan, N., Elston, K., Battle, C., Newey, L., Rees, T., Harford, R., Brinkworth, E., Croft, M., Bandla, N., Gellamucho, M., Turner, H., Quinn, A., Hussain, I., Bradley, R., Griffiths, R., Scriven, J., Puxty, A., Cathcart, S., Salutous, D., Duffy, K., Puxty, K., Joseph, A., Herdman-Grant, R., Simms, R., Swain, A., Naranjo, A., Crowe, R., Sollesta, K., Loveridge, A., Baptista, D., Morino, E., Davey, M., Golden, D., Cuesta, J. M., Haldeos, A., Bakthavatsalam, D., Elhassan, M., Xavier, K., Ganesan, A., Abdelrazik, D. P. M., Akeroyd, L., Bano, S., Bromley, M., Sellick, K., Gurr, L., Nagarajan, V., Szedlak, P., Cupitt, J., Stoddard, E., Benham, L., Slawson, N., Bradshaw, Z., Caswell, M., Melling, S., Bamford, P., Cawley, K., Jeffrey, H., London, E., Sainsbury, H., Nagra, I., Nasir, F., Dunmore, C., Abraheem, A., Al-Moasseb, M., Girach, R., Brantwood, C., Alexander, P., Bradley-Potts, J., Felton, T., Manna, S., Farnell-Ward, S., Leaver, S., Queiroz, J., Maccacari, E., Dawson, D., Delgado, C. C., Saluzzio, R. P., Ezeobu, O., Ding, L., Sicat, C., Kanu, R., Investigators, T. GMICC., Consortium, GMICC., co-investigators, GMICC., team, C. M. A. L., team, D. A., Barts Health NHS Trust London, UK., Guys and St Thomas’ Hospital London, UK., James Cook University Hospital Middlesburgh, UK., The Royal Liverpool University Hospital Liverpool, UK., King’s College Hospital London, UK., Royal Infirmary of Edinburgh Edinburgh, UK., John Radcliffe Hospital Oxford, UK., Addenbrooke’s Hospital Cambridge, UK., Morriston Hospital Swansea, UK., Ashford and St Peter’s Hospital Surrey, UK., Royal Stoke University Hospital Staffordshire, UK., Queen Elizabeth Hospital Birmingham, UK., Glasgow Royal Infirmary Glasgow, UK., Kingston Hospital Surrey, UK., The Tunbridge Wells Hospital and Maidstone Hospital Kent, UK., North Middlesex University Hospital NHS Trust London, UK., Bradford Royal Infirmary Bradford, UK., Blackpool Victoria Hospital Blackpool, UK., Countess of Chester Hospital Chester, UK., Wythenshawe Hospital Manchester, UK. & St George’s Hospital London, UK., 11 Dec 2020, In: Nature.

    Research output: Contribution to journalArticlepeer-review

  18. Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

    Seow, J., Graham, C., Merrick, B., Acors, S., Pickering, S., Steel, K. J. A., Hemmings, O., O’Byrne, A., Kouphou, N., Galao, R. P., Betancor, G., Wilson, H. D., Signell, A. W., Winstone, H., Kerridge, C., Huettner, I., Jimenez-Guardeño, J. M., Lista, M. J., Temperton, N., Snell, L. B. & 22 others, Bisnauthsing, K., Moore, A., Green, A., Martinez, L., Stokes, B., Honey, J., Izquierdo-Barras, A., Arbane, G., Patel, A., Tan, M. K. I., O’Connell, L., O’Hara, G., MacMahon, E., Douthwaite, S., Nebbia, G., Batra, R., Martinez-Nunez, R., Shankar-Hari, M., Edgeworth, J. D., Neil, S. J. D., Malim, M. H. & Doores, K. J., 1 Dec 2020, In: Nature Microbiology. 5, 12, p. 1598-1607 10 p.

    Research output: Contribution to journalArticlepeer-review

  19. Outcomes in mechanically ventilated patients with hypoxaemic respiratory failure caused by COVID-19

    Camporota, L., Sanderson, B., Dixon, A., Vasques, F., Jones, A. & Shankar-Hari, M., Dec 2020, In: British Journal of Anaesthesia. 125, 6, p. e480-e483

    Research output: Contribution to journalLetterpeer-review

  20. Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study

    Sinha, P., Calfee, C. S., Cherian, S., Brealey, D., Cutler, S., King, C., Killick, C., Richards, O., Cheema, Y., Bailey, C., Reddy, K., Delucchi, K. L., Shankar-Hari, M., Gordon, A. C., Shyamsundar, M., O'Kane, C. M., McAuley, D. F. & Szakmany, T., Dec 2020, In: The Lancet Respiratory Medicine. 8, 12, p. 1209-1218 10 p.

    Research output: Contribution to journalArticlepeer-review

  21. COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland

    ICNARC COVID-19 Team, 1 Nov 2020, In: Intensive Care Medicine. 46, 11, p. 2035-2047 13 p.

    Research output: Contribution to journalArticlepeer-review

  22. A dynamic COVID-19 immune signature includes associations with poor prognosis

    Laing, A. G., Lorenc, A., del Molino del Barrio, I., Das, A., Fish, M., Monin, L., Muñoz-Ruiz, M., McKenzie, D. R., Hayday, T. S., Francos-Quijorna, I., Kamdar, S., Joseph, M., Davies, D., Davis, R., Jennings, A., Zlatareva, I., Vantourout, P., Wu, Y., Sofra, V., Cano, F. & 30 others, Greco, M., Theodoridis, E., Freedman, J., Gee, S., Chan, J. N. E., Ryan, S., Bugallo-Blanco, E., Peterson, P., Kisand, K., Haljasmägi, L., Chadli, L., Moingeon, P., Martinez, L., Merrick, B., Bisnauthsing, K., Brooks, K., Ibrahim, M. A. A., Mason, J., Lopez Gomez, F., Babalola, K., Abdul-Jawad, S., Cason, J., Mant, C., Seow, J., Graham, C., Doores, K. J., Di Rosa, F., Edgeworth, J., Shankar-Hari, M. & Hayday, A. C., 1 Oct 2020, In: Nature Medicine. 26, 10, p. 1623-1635 13 p.

    Research output: Contribution to journalArticlepeer-review

  23. Development, Validation, and Clinical Utility Assessment of a Prognostic Score for 1-Year Unplanned Rehospitalization or Death of Adult Sepsis Survivors

    Shankar-Hari, M., Rubenfeld, G. D., Ferrando-Vivas, P., Harrison, D. A. & Rowan, K., 14 Sep 2020, In: JAMA Network open. 3, 9, p. e2013580

    Research output: Contribution to journalArticlepeer-review

  24. Microvascular injury and hypoxic damage: emerging neuropathological signatures in COVID-19

    Jaunmuktane, Z., Mahadeva, U., Green, A., Sekhawat, V., Barrett, N. A., Childs, L., Shankar-Hari, M., Thom, M., Jäger, H. R. & Brandner, S., 1 Sep 2020, In: Acta Neuropathologica. 140, 3, p. 397-400 4 p.

    Research output: Contribution to journalLetterpeer-review

  25. Use of Hydrocortisone Based on Plasma Biomarkers in Patients with Septic Shock: Another One Bites the Dust?

    Møller, M. H., Shankar-Hari, M. & Alhazzani, W., 1 Sep 2020, In: American Journal of Respiratory and Critical Care Medicine. 202, 5, p. 644-646 3 p.

    Research output: Contribution to journalEditorialpeer-review

  26. Translational Research in the Time of COVID-19-Dissolving Boundaries

    Edgeworth, J. D., Batra, R., Nebbia, G., Bisnauthsing, K., MacMahon, E., Sudhanva, M., Douthwaite, S., Goldenberg, S., O'Hara, G., Shankar-Hari, M., Doores, K. J., Martinez-Nunez, R., Hemsley, C., Price, N. M., Lockett, J., Lechler, R. I., Neil, S. J. D. & Malim, M. H., Sep 2020, In: PLoS Pathogens. 16, 9, p. e1008898 e1008898.

    Research output: Contribution to journalArticlepeer-review

  27. Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak

    ESICM, 8 Aug 2020, In: Annals of Intensive Care. 10, 1, p. 110 110.

    Research output: Contribution to journalArticlepeer-review

  28. International variation in the management of severe COVID-19 patients

    Azoulay, E., de Waele, J., Ferrer, R., Staudinger, T., Borkowska, M., Povoa, P., Iliopoulou, K., Artigas, A., Schaller, S. J., Shankar-Hari, M., Pellegrini, M., Darmon, M., Kesecioglu, J. & Cecconi, M., 5 Aug 2020, In: CRITICAL CARE. 24, 1, 1 p., s13054-020-03194-w.

    Research output: Contribution to journalArticlepeer-review

  29. Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials

    Shankar-Hari, M., Estcourt, L., Harvala, H., Roberts, D., Menon, D. K. & Consortium, O. B. O. T. U. K. SARS-C. C. P. E. SCE., 20 Jul 2020, In: CRITICAL CARE. 24, 1, 449.

    Research output: Contribution to journalReview articlepeer-review

  30. Rethinking animal models of sepsis - working towards improved clinical translation whilst integrating the 3Rs

    Nandi, M., Jackson, S. K., Macrae, D., Shankar-Hari, M., Tremoleda, J. L. & Lilley, E., 17 Jul 2020, In: Clinical Science. 134, 13, p. 1715-1734 20 p.

    Research output: Contribution to journalReview articlepeer-review

  31. ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial

    Wilkinson, T., Dixon, R., Page, C., Carroll, M., Griffiths, G., Ho, L-P., De Soyza, A., Felton, T., Lewis, K. E., Phekoo, K., Chalmers, J. D., Gordon, A., McGarvey, L., Doherty, J., Read, R. C., Shankar-Hari, M., Martinez-Alier, N., O’Kelly, M., Duncan, G., Walles, R. & 4 others, Sykes, J., Summers, C., Singh, D. & Collaborators, O. B. O. T. ACCORD., 4 Jul 2020, In: Trials. 21, 1, 1 p., 691.

    Research output: Contribution to journalArticlepeer-review

  32. The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study

    McGuigan, P. J., Shankar-Hari, M., Harrison, D. A., Laffey, J. G. & McAuley, D. F., 12 Jun 2020, In: CRITICAL CARE. 24, 1, p. 336 336.

    Research output: Contribution to journalArticlepeer-review

  33. Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial

    Gorman, E., Shankar-Hari, M., Hopkins, P., Tunnicliffe, W. S., Perkins, G. D., Silversides, J., McGuigan, P., Jackson, C., Boyle, R., McFerran, J., McDowell, C., Campbell, C., McFarland, M., Smythe, J., Thompson, J., Williams, B., Curley, G., Laffey, J. G., Clarke, M., O'Kane, C. & 1 others, McAuley, D. F., 3 Jun 2020, In: Trials. 21, 1, 1 p., 462.

    Research output: Contribution to journalLetterpeer-review

  34. Relationship between norepinephrine dose, tachycardia and outcome in septic shock: A multicentre evaluation

    Domizi, R., Calcinaro, S., Harris, S., Beilstein, C., Boerma, C., Chiche, J-D., D'Egidio, A., Damiani, E., Donati, A., Koetsier, P. M., Madden, M. P., McAuley, D. F., Morelli, A., Pelaia, P., Royer, P., Shankar-Hari, M., Wickboldt, N., Zolfaghari, P. & Singer, M., Jun 2020, In: Journal of Critical Care. 57, p. 185-190 6 p.

    Research output: Contribution to journalArticlepeer-review

  35. Demographic Shifts, Case Mix, Activity, and Outcome for Elderly Patients Admitted to Adult General ICUs in England, Wales, and Northern Ireland

    Jones, A., Toft-Petersen, A. P., Shankar-Hari, M., Harrison, D. A. & Rowan, K. M., 1 Apr 2020, In: Critical Care Medicine. 48, 4, p. 466-474 9 p.

    Research output: Contribution to journalArticlepeer-review

  36. Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis

    Shankar-Hari, M., Saha, R., Wilson, J., Prescott, H. C., Harrison, D., Rowan, K., Rubenfeld, G. D. & Adhikari, N. K. J., 1 Apr 2020, In: Intensive Care Medicine. 46, 4, p. 619-636 18 p.

    Research output: Contribution to journalReview articlepeer-review

  37. Lack of Clinical Benefit of Interferon β-1a Among Patients With Severe Acute Respiratory Distress Syndrome: Time to Overhaul Drug Trials in ARDS?

    Shankar-Hari, M. & Calfee, C. S., 25 Feb 2020, In: JAMA. 323, 8, p. 713-715 3 p.

    Research output: Contribution to journalEditorialpeer-review

  38. Could stress ulcer prophylaxis increase mortality in high-acuity patients?

    Harhay, M. O., Young, P. J. & Shankar-Hari, M., 19 Feb 2020, In: Intensive Care Medicine. 46, 4, p. 793-795 3 p.

    Research output: Contribution to journalEditorialpeer-review

  39. Is T Cell Exhaustion a Treatable Trait in Sepsis?

    Fish, M., Swanson, C. M. & Shankar-Hari, M., 12 Feb 2020, Annual Update in Intensive Care and Emergency Medicine 2020. Vincent, J-L. (ed.). Cham: Springer International Publishing, p. 271-279 9 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  40. Maternal Risk Modeling in Critical Care-Development of a Multivariable Risk Prediction Model for Death and Prolonged Intensive Care

    Simpson, N. B., Shankar-Hari, M., Rowan, K. M., Cecconi, M., von Dadelszen, P., Huning, E. Y-S., Magee, L. A., Payne, B. A., Quinn, A. C. & Harrison, D. A., 9 Jan 2020, In: Critical Care Medicine. p. 663-672 10 p.

    Research output: Contribution to journalArticlepeer-review

  41. Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis?

    Shankar-Hari, M., Fish, M. & Azoulay, E., 1 Jan 2020, In: Intensive Care Medicine. 46, 1, p. 119-121 3 p.

    Research output: Contribution to journalEditorialpeer-review

  42. Trials on oxygen supplementation in sepsis: better late than never

    Perner, A., De Jong, A. & Shankar-Hari, M., 1 Jan 2020, In: Intensive Care Medicine. 46, 1, p. 116-118 3 p.

    Research output: Contribution to journalEditorialpeer-review

  43. Current gaps in sepsis immunology: new opportunities for translational research

    Rubio, I., Osuchowski, M. F., Shankar-Hari, M., Skirecki, T., Winkler, M. S., Lachmann, G., La Rosée, P., Monneret, G., Venet, F., Bauer, M., Brunkhorst, F. M., Kox, M., Cavaillon, J-M., Uhle, F., Weigand, M. A., Flohé, S. B., Wiersinga, W. J., Martin-Fernandez, M., Almansa, R., Martin-Loeches, I. & 10 others, Torres, A., Giamarellos-Bourboulis, E. J., Girardis, M., Cossarizza, A., Netea, M. G., van der Poll, T., Scherag, A., Meisel, C., Schefold, J. C. & Bermejo-Martín, J. F., 1 Dec 2019, In: Lancet Infectious Diseases. 19, 12, p. e422-e436

    Research output: Contribution to journalReview articlepeer-review

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