Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Marc-David Ruepp is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons
Hölbling, B. V., Gupta, Y., Marchi, P. M., Atilano, M. L., Flower, M., Ureña, E., Goulden, R. A., Dobbs, H. K., Katona, E., Mikheenko, A., Giblin, A., Awan, A. R., Fisher-Ward, C. L., O'Brien, N., Vaizoglu, D., Kempthorne, L., Wilson, K. M., Gittings, L. M., Carcolé, M. & Ruepp, M.-D. & 9 others, , 27 May 2025, In: Cell Reports. 44, 5, p. 115695 115695.Research output: Contribution to journal › Article › peer-review
Open Access -
Cognition on the move: Examining the role of physical exercise and neurogenesis in counteracting cognitive aging
Farmand, S., Du Preez, A., Kim, C., de Lucia, C., Ruepp, M. D., Stubbs, B. & Thuret, S., 8 Apr 2025, In: AGEING RESEARCH REVIEWS. 107, 102725.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS
Schweingruber, C., Nijssen, J., Mechtersheimer, J., Reber, S., Lebœuf, M., O’Brien, N. L., Mei, I., Hedges, E., Keuper, M., Benitez, J. A., Radoi, V., Jastroch, M., Ruepp, M.-D. & Hedlund, E., 19 May 2025, In: Nature communications. 16, 1, 4633.Research output: Contribution to journal › Article › peer-review
Open Access -
G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes
Giraud, G., Rodà, M., Huchon, P., Michelet, M., Maadadi, S., Jutzi, D., Montserret, R., Ruepp, M. D., Parent, R., Combet, C., Zoulim, F. & Testoni, B., 21 Mar 2024, In: Nucleic Acids Research. 52, 5, p. 2290-2305 16 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons
Shum, C., Hedges, E. C., Allison, J., Lee, Y. B., Arias, N., Cocks, G., Chandran, S., Ruepp, M. D., Shaw, C. E. & Nishimura, A. L., 18 Jan 2024, In: Stem cell reports. 19, 2, p. 187-195 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus)
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RNA-trans-splicing as therapeutic modality for C9orf72 Amyotrophic Lateral Sclerosis
Ruepp, M.-D. (Primary Investigator), Mizielinska, S. (Co-Investigator) & academic, A. (Co-Investigator)
UKDRI UK Dementia Research Institute
1/05/2025 → 30/04/2027
Project: Research
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Nuclear to synaptic signalling dysregulation by Annexin A11 in ALS
Smith, B. (Primary Investigator), Mitchell, J. (Co-Investigator), Mizielinska, S. (Co-Investigator), Ruepp, M.-D. (Co-Investigator), Troakes, C. (Co-Investigator) & Vance, C. (Co-Investigator)
MNDA Motor Neurone Disease Association
1/04/2025 → 31/03/2026
Project: Research
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Decoding spatio-temporal kinetics of local mRNA translation in neurons using a new single-molecule imaging platform
Ruepp, M.-D. (Primary Investigator) & Khuperkar, D. (Co-Investigator)
UKDRI UK Dementia Research Institute
1/04/2025 → 31/03/2026
Project: Research
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Synaptic dysfunction in ALS-FUS
Vance, C. (Primary Investigator), Ruepp, M.-D. (Co-Investigator) & Shaw, C. (Co-Investigator)
MNDA Motor Neurone Disease Association
1/03/2025 → 29/02/2028
Project: Research
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UKDRI MND Theme Funding - Contribution to PhD Studentship TDP-43 Cell Models
Mizielinska, S. (Primary Investigator) & Ruepp, M.-D. (Co-Investigator)
UKDRI UK Dementia Research Institute
1/02/2025 → 31/01/2026
Project: Research