Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 5 Gender Equality -
SDG 10 Reduced Inequalities
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Collaborations and top research areas from the last five years
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Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection
Yang, F., Beltran-Lobo, P., Sung, K., Goldrick, C., Croft, C. L., Nishimura, A., Hedges, E., Mahiddine, F., Troakes, C., Golde, T. E., Perez-Nievas, B. G., Hanger, D. P., Noble, W. & Jimenez-Sanchez, M., Mar 2024, In: Science Advances. 10, 12, p. eadk9884 eadk9884.Research output: Contribution to journal › Article › peer-review
Open Access31 Citations (Scopus) -
Truncated tau disrupts autophagy and endolysosomal systems
Pollack, S., Hanger, D., Noble, W. & Jimenez Sanchez, M., 8 Oct 2024, In: Autophagy Reports. 3, 1Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Truncated tau interferes with the autophagy and endolysosomal pathway and results in lipid accumulation
Pollack, S. J., Dakkak, D., Guo, T., Chennell, G., Gomez-Suaga, P., Noble, W., Jimenez-Sanchez, M. & Hanger, D. P., 15 Jul 2024, In: Cellular and molecular life sciences : CMLS. 81, 1, 16 p., 304.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)23 Downloads (Pure) -
Astrocyte adaptation in Alzheimer's disease: a focus on astrocytic P2X7R
Beltran-Lobo, P., Reid, M. J., Jimenez-Sanchez, M., Verkhratsky, A., Perez-Nievas, B. G. & Noble, W., Mar 2023, In: Essays in Biochemistry. 67, 1, p. 119-130 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access26 Citations (Scopus) -
Microglial cytokines poison neuronal autophagy via CCR5, a druggable target
Festa, B. P., Siddiqi, F. H., Jimenez-Sanchez, M. & Rubinsztein, D. C., 26 Jun 2023, (E-pub ahead of print) In: Autophagy. p. 1-3 3 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (Scopus)
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Tau biosensor models to elucidate astrocyte vulnerability to tau disease conformations
Jimenez Sanchez, M. (Primary Investigator)
1/04/2026 → 30/09/2027
Project: Research
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Halting prion-like propagation of tau by astrocyte-secreted chaperones
Jimenez Sanchez, M. (Primary Investigator) & Mitchell, J. (Co-Investigator)
1/06/2025 → 31/05/2028
Project: Research
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Elucidating the non-cell autonomous role of FTD/ALS-linked mutations in p62 in iPSCs-derived astrocytes
Jimenez Sanchez, M. (Primary Investigator), Mizielinska, S. (Co-Investigator) & Ruepp, M.-D. (Co-Investigator)
1/10/2024 → 31/03/2026
Project: Research
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Alzheimer’s Research UK London Network Centre Grant Sub-project: Maria Jimenez Sanchez
Jimenez Sanchez, M. (Primary Investigator)
29/01/2024 → 15/06/2024
Project: Research
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MRC Transition Support Award [CDA] [Maria Jimenez-Sanchez]
Jimenez Sanchez, M. (Primary Investigator)
23/02/2022 → 23/02/2025
Project: Research