Marzia Malcangio

Reinhold, A. K., Krug, S. M., Salvador, E., Sauer, R. S., Karl-Schöller, F., Malcangio, M., Sommer, C. & Rittner, H. L., 1 Sept 2022, In: Annals of the New York Academy of Sciences. 1515, 1, p. 184-195 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Pain-resolving microglia

Sideris-Lampretsas, G. & Malcangio, M., 1 Apr 2022, In: Science. 376, 6588, p. 33-34 2 p.

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

2021

Changes in blood–spinal cord barrier permeability and neuroimmune interactions in the underlying mechanisms of chronic pain

Montague-Cardoso, K. & Malcangio, M., 2021, In: Pain Reports. 6, 1, e879.

Research output: Contribution to journal › Review article › peer-review

Open Access

20 Citations (Scopus)

Microglial heterogeneity in chronic pain

Sideris-Lampretsas, G. & Malcangio, M., Aug 2021, In: Brain, Behavior, and Immunity. 96, p. 279-289 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Citations (Scopus)

Pain in the neurodegenerating brain: insights into pharmacotherapy for Alzheimer disease and Parkinson disease

Lawn, T., Aman, Y., Rukavina, K., Sideris-Lampretsas, G., Howard, M., Ballard, C., Ray Chaudhuri, K. & Malcangio, M., 1 Apr 2021, In: Pain. 162, 4, p. 999-1006 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Citations (Scopus)

2020

Cathepsin S as a potential therapeutic target for chronic pain

Montague-Cardoso, K. & Malcangio, M., 11 May 2020, In: Medicine in Drug Discovery. 5 p., 100047.

Research output: Contribution to journal › Review article › peer-review

Changes in vascular permeability in the spinal cord contribute to chemotherapy-induced neuropathic pain

Montague-Cardoso, K., Pitcher, T., Chisolm, K., Salera, G., Lindstrom, E., Hewitt, E., Solito, E. & Malcangio, M., 1 Jan 2020, In: Brain Behavior and Immunity. 83, p. 248-259 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Citations (Scopus)

Imbalance of pro-resolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis

Malcangio, M., Allen, B., Montague-Cardoso, K., Simeoli, R., Colas, R. A., Oggero, S., Villar, B., McNaughton, P., Dalli, J., Perretti, M. & Sher, E., 23 Apr 2020, (Accepted/In press) In: Pain.

Research output: Contribution to journal › Article › peer-review

Open Access

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29 Citations (Scopus)

65 Downloads (Pure)

The role of microRNAs in neurons and neuroimmune communication in the dorsal root ganglia in chronic pain

Montague-Cardoso, K. & Malcangio, M., 14 Sept 2020, In: Neuroscience Letters. 735, 135230.

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Translational value of preclinical models for rheumatoid arthritis pain

Malcangio, M., 1 Jul 2020, In: Pain. 161, 7, p. 1399-1400 2 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

2019

Cathepsin S acts via protease-activated receptor 2 to activate sensory neurons and induce itch-like behaviour

Chung, K., Pitcher, T., Grant, A., Hewitt, E., Lindstrom, E. & Malcangio, M. A. M., Aug 2019, In: Neurobiology of Pain. 6, 100032.

Research output: Contribution to journal › Article › peer-review

Open Access

File

23 Citations (Scopus)

133 Downloads (Pure)

Pain in Parkinson's disease: new concepts in pathogenesis and treatment

Rukavina, K., Leta, V., Sportelli, C., Buhidma, Y., Duty, S., Malcangio, M. & Ray Chaudhuri, K., Aug 2019, In: Current Opinion in Neurology. 32, 4, p. 579-588 10 p.

Research output: Contribution to journal › Review article › peer-review

64 Citations (Scopus)

Role of the immune system in neuropathic pain

Malcangio, M., 1 Jan 2019, In: Scandinavian Journal of Pain.

Research output: Contribution to journal › Review article › peer-review

140 Citations (Scopus)

2018

A novel interaction between CX3CR1 and CCR2 signalling in monocytes constitutes an underlying mechanism for persistent vincristine-induced pain

Montague, K., Simeoli, R., Sousa-Valente, J. & Malcangio, M., 2018, In: Journal of neuroinflammation. 15, 101

Research output: Contribution to journal › Article › peer-review

Open Access

File

43 Citations (Scopus)

228 Downloads (Pure)

A refined rat primary neonatal microglial culture method that reduces time, cost and animal use

Georgieva, M., Leeson-Payne, A., Dumitrascuta, M., Rajnicek, A., Malcangio, M. & Huang, W., 27 Apr 2018, (E-pub ahead of print) In: Journal of Neuroscience Methods.

Research output: Contribution to journal › Article › peer-review

Open Access

File

8 Citations (Scopus)

155 Downloads (Pure)

Impaired chronic pain-like behaviour and disruption of the opioidergic system in the TASTPM mouse model of Alzheimer’s disease

Malcangio, M. A. M., Ballard, C. G., Aman, Y. & Pitcher, T., 10 Jul 2018, (E-pub ahead of print) In: EUROPEAN JOURNAL OF PAIN.

Research output: Contribution to journal › Article › peer-review

Open Access

File

14 Citations (Scopus)

113 Downloads (Pure)

2017

Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG

Nascimento, D. S. M., Potes, C. S., Soares, M. L., Ferreira, A. C., Malcangio, M., Castro-Lopes, J. M. & Neto, F. L. M., 26 May 2017, (E-pub ahead of print) In: Molecular Neurobiology. p. 1-17 17 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma

Simeoli, R., Montague, K., Jones, H. R., Castaldi, L., Chambers, D., Kelleher, J. H., Vacca, V., Pitcher, T., Grist, J., Al-Ahdal, H., Wong, L-F., Perretti, M., Lai, J., Mouritzen, P., Heppenstall, P. & Malcangio, M., 24 Nov 2017, In: Nature Communications. 8, 1, p. 1778 1 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

228 Citations (Scopus)

225 Downloads (Pure)

GABAB receptors and pain

Malcangio, M., 11 May 2017, (E-pub ahead of print) In: Neuropharmacology.

Research output: Contribution to journal › Article › peer-review

Open Access

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54 Citations (Scopus)

544 Downloads (Pure)

Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

Oehler, B., Kistner, K., Martin, C., Schiller, J., Mayer, R., Mohammadi, M., Sauer, R. S., Filipovic, M. R., Nieto, F. R., Kloka, J., Pflücke, D., Hill, K., Schaefer, M., Malcangio, M., Reeh, P. W., Brack, A., Blum, R. & Rittner, H. L., 14 Jul 2017, In: Scientific Reports. 7, 1, 5447.

Research output: Contribution to journal › Article › peer-review

Open Access

File

50 Citations (Scopus)

190 Downloads (Pure)

Role of TrkA signalling and mast cells in the initiation of osteoarthritis pain in the monoiodoacetate model

De Sousa Valente, J., Calvo, L., Vacca, V., Simeoli, R., Arévalo, J. C. & Malcangio, M., 24 Aug 2017, (E-pub ahead of print) In: Osteoarthritis and Cartilage.

Research output: Contribution to journal › Article › peer-review

Open Access

File

45 Citations (Scopus)

268 Downloads (Pure)

Spinal mechanisms of neuropathic pain: Is there a P2X4-BDNF controversy?

Malcangio, M., 17 May 2017, (E-pub ahead of print) In: Neurobiology of Pain. 1, p. 1-5 5 p.

Research output: Contribution to journal › Short survey › peer-review

Open Access

20 Citations (Scopus)

The therapeutic potential of targeting chemokine signalling in the treatment of chronic pain

Montague, K. & Malcangio, M., 24 Feb 2017, (E-pub ahead of print) In: Journal of Neurochemistry.

Research output: Contribution to journal › Article › peer-review

Open Access

File

35 Citations (Scopus)

219 Downloads (Pure)

2016

Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner

Fernandes, E. S., Russell, F. A., Alawi, K. M., Sand, C., Liang, L., Salamon, R., Bodkin, J. V., Aubdool, A. A., Arno, M., Gentry, C., Smillie, S. J., Bevan, S., Keeble, J. E., Malcangio, M. & Brain, S. D., 11 Jan 2016, In: Arthritis Research and Therapy. 18, 1, 7.

Research output: Contribution to journal › Article › peer-review

Open Access

File

38 Citations (Scopus)

188 Downloads (Pure)

Microglia and chronic pain

Malcangio, M., May 2016, 2 p.

Research output: Other contribution

19 Citations (Scopus)

Neuron-immune mechanisms contribute to pain in early stages of arthritis

Nieto, F. R., Clark, A. K., Grist, J., Hathway, G. J., Chapman, V. & Malcangio, M., 29 Apr 2016, In: Journal of neuroinflammation. 13, 1, 96.

Research output: Contribution to journal › Article › peer-review

Open Access

File

84 Citations (Scopus)

181 Downloads (Pure)

Recent advances in neuroimmune interactions in neuropathic pain: The role of microglia

Old, E. A., Nicol, L. S. C. & Malcangio, M., 5 Mar 2016, An Introduction to Pain and Nervous System Disorders. WILEY-BLACKWELL, p. 123-147 25 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Reduced thermal sensitivity and increased opioidergic tone in the TASTPM mouse model of Alzheimer's disease

Aman, Y., Pitcher, T., Simeoli, R., Ballard, C. & Malcangio, M., Oct 2016, In: Pain. 157, 10, p. 2285-2296

Research output: Contribution to journal › Article › peer-review

Open Access

File

22 Citations (Scopus)

194 Downloads (Pure)

Role of extracellular calcitonin gene-related peptide in spinal cord mechanisms of cancer-induced bone pain

Hansen, R. R., Vacca, V., Pitcher, T., Clark, A. K. & Malcangio, M., 1 Mar 2016, In: Pain. 157, 3, p. 666-676 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

27 Citations (Scopus)

415 Downloads (Pure)

The monoiodoacetate model of osteoarthritis pain in the mouse

Pitcher, T., Sousa-Valente, J. & Malcangio, M., 16 May 2016, In: Journal of Visualized Experiments. 2016, 111, e53746.

Research output: Contribution to journal › Article › peer-review

Open Access

File

136 Citations (Scopus)

200 Downloads (Pure)

2015

Calcitonin gene-related peptide-expressing sensory neurons and spinal microglial reactivity contribute to pain states in collagen-induced arthritis

Nieto, F. R., Clark, A. K., Grist, J., Chapman, V. & Malcangio, M., Jun 2015, In: Arthritis and Rheumatology. 67, 6, p. 1668-1677 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

53 Citations (Scopus)

143 Downloads (Pure)

Chronic pain: New insights in molecular and cellular mechanisms

Luongo, L., Malcangio, M., Salvemini, D. & Starowicz, K., 2015, In: BioMed Research International. 2015, 676725.

Research output: Contribution to journal › Article › peer-review

Open Access

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11 Citations (Scopus)

182 Downloads (Pure)

Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice

Ogbonna, A. C., Clark, A. K. & Malcangio, M., 28 Jun 2015, In: AGE. 37, 3, 54.

Research output: Contribution to journal › Article › peer-review

Open Access

File

24 Citations (Scopus)

139 Downloads (Pure)

Selective activation of microglia facilitates synaptic strength

Clark, A. K., Gruber-Schoffnegger, D., Drdla-Schutting, R., Gerhold, K. J., Malcangio, M. & Sandkühler, J., 18 Mar 2015, In: Journal of Neuroscience. 35, 11, p. 4552-4570 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

140 Citations (Scopus)

275 Downloads (Pure)

The role of glia in the spinal cord in neuropathic and inflammatory pain

Amy Old, E., Clark, A. K. & Malcangio, M., Jan 2015, Handbook of Experimental Pharmacology. Vol. 227. p. 145-170 26 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

151 Citations (Scopus)

The role of G-protein receptor 84 in experimental neuropathic pain

Nicol, L. S. C., Dawes, J. M., Russa, F. L., Didangelos, A., Clark, A. K., Gentry, C., Grist, J., Davies, J. B., Malcangio, M. & McMahon, S. B., 10 Jun 2015, In: Journal of Neuroscience. 35, 23, p. 8959-8969 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

51 Citations (Scopus)

208 Downloads (Pure)

2014

Fractalkine/CX3CR1 signaling during neuropathic pain

Clark, A. K. & Malcangio, M., 7 May 2014, In: Frontiers in cellular neuroscience. 8, 7 p., 121.

Research output: Contribution to journal › Literature review › peer-review

Open Access

128 Citations (Scopus)

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

Old, E. A., Nadkarni, S., Grist, J., Gentry, C., Bevan, S., Kim, K-W., Mogg, A. J., Perretti, M. & Malcangio, M., 31 May 2014, In: Journal of Clinical Investigation. 124, 5, p. 2023-2036 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

139 Citations (Scopus)

2013

Astrocytes-Multitaskers in chronic pain

Hansen, R. R. & Malcangio, M., 15 Sept 2013, In: European Journal of Pharmacology. 716, 1-3, p. 120-128 9 p., N/A.

Research output: Contribution to journal › Literature review › peer-review

49 Citations (Scopus)

microRNAs in nociceptive circuits as predictors of future clinical applications

Kress, M., Hüttenhofer, A., Landry, M., Kuner, R., Favereaux, A., Greenberg, D., Bednarik, J., Heppenstall, P., Kronenberg, F., Malcangio, M., Rittner, H., Üçeyler, N., Trajanoski, Z., Mouritzen, P., Birklein, F., Sommer, C. & Soreq, H., 17 Oct 2013, In: Frontiers in Molecular Neuroscience. 6, OCT

Research output: Contribution to journal › Article › peer-review

70 Citations (Scopus)

Neuropathic pain and cytokines: Current perspectives

Clark, A. K., Old, E. A. & Malcangio, M., 20 Nov 2013, In: Journal of Pain Research. 6, p. 803-814 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

281 Citations (Scopus)

Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice

Ogbonna, A. C., Clark, A. K., Gentry, C., Hobbs, C. & Malcangio, M., Apr 2013, In: EUROPEAN JOURNAL OF PAIN. 17, 4, p. 514-526 13 p., N/A.

Research output: Contribution to journal › Article › peer-review

78 Citations (Scopus)

2012

Assessment and treatment of pain in people with dementia

Corbett, A., Husebo, B., Malcangio, M., Staniland, A., Cohen-Mansfield, J., Aarsland, D. & Ballard, C., May 2012, In: Nature Reviews Neurology. 8, 5, p. 264-274 11 p., N/A.

Research output: Contribution to journal › Article › peer-review

266 Citations (Scopus)

Chemokine mediated neuron-glia communication and aberrant signalling in neuropathic pain states

Old, E. A. & Malcangio, M., Feb 2012, In: Current Opinion in Pharmacology. 12, 1, p. 67 - 73 7 p.

Research output: Contribution to journal › Article › peer-review

98 Citations (Scopus)

Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

Minett, M. S., Nassar, M. A., Clark, A. K., Passmore, G., Dickenson, A. H., Wang, F., Malcangio, M. & Wood, J. N., 24 Apr 2012, In: Nature Communications. 3, N/A, p. N/A 9 p., 791.

Research output: Contribution to journal › Article › peer-review

Open Access

225 Citations (Scopus)

Microglial signalling mechanisms: Cathepsin S and Fractalkine

Clark, A. K. & Malcangio, M., Apr 2012, In: Experimental Neurology. 234, 2, p. 283 - 292 10 p.

Research output: Contribution to journal › Literature review › peer-review

120 Citations (Scopus)

Marzia Malcangio

Research output

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