Projects per year
- 1 - 50 out of 52 results
Search results
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Active
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A comprehensive approach to the genetic, molecular and functional impact of rare titin missense variants in dilated cardiomyopathy
Gautel, M. (Primary Investigator), Fraternali, F. (Co-Investigator) & Zelezniak, A. (Co-Investigator)
9/01/2023 → 8/01/2027
Project: Research
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Structure and Cellular Dynamics of the Sarcomere
Gautel, M. (Primary Investigator)
1/02/2020 → 31/01/2026
Project: Research
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MUSCLEAUTOPHAGY
Jungbluth, H. (Primary Investigator), Gautel, M. (Co-Investigator) & Miller, C. (Co-Investigator)
1/01/1950 → …
Project: Research
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Finished
Quantitative Multidimensional Imaging: A centre for Fluorescence Lifetime Imaging Microscopy
Ameer-Beg, S. (Primary Investigator), Burrone, J. (Co-Investigator), Gautel, M. (Co-Investigator), Krause, M. (Co-Investigator), Mann, Z. (Co-Investigator), Martin Serrano, J. (Co-Investigator), Neves, J. (Co-Investigator), Padilla Parra, S. (Co-Investigator), Parsons, M. (Co-Investigator), Poland, S. (Co-Investigator), Serio, A. (Co-Investigator) & academic, A. (Co-Investigator)
1/11/2022 → 31/03/2023
Project: Research
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A cryo-electron microscope for structural biology (including single-particle and tomography) at KCL.
Conte, M. (Primary Investigator), Atherton, J. (Co-Investigator), Beavil, A. (Co-Investigator), Bergeron, J. (Co-Investigator), Booth, P. (Co-Investigator), Burrone, J. (Co-Investigator), Carlton, J. (Co-Investigator), De Nicola, G. (Co-Investigator), Ehler, E. (Co-Investigator), Fleck, R. (Co-Investigator), Fraternali, F. (Co-Investigator), Garnett, J. (Co-Investigator), Gautel, M. (Co-Investigator), Isaacson, R. (Co-Investigator), Kampourakis, T. (Co-Investigator), Malim, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Neil, S. (Co-Investigator), Odendall, C. (Co-Investigator), Pfuhl, M. (Co-Investigator), Politis, A. (Co-Investigator), Steiner, R. (Co-Investigator) & Sutton, B. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/08/2022 → 31/07/2023
Project: Research
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BHF Centre Gover PhD Studentship
Gautel, M. (Primary Investigator)
1/01/2022 → 31/01/2025
Project: Research
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BHF Centre pump-prime Gautel
Gautel, M. (Primary Investigator)
1/06/2021 → 31/05/2022
Project: Research
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Isothermal titration calorimetry instrumentation for structural biology, biological mechanisms and drug discovery
Conte, M. (Primary Investigator), Gautel, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Isaacson, R. (Co-Investigator), M. Barry, S. (Co-Investigator), Garnett, J. (Co-Investigator), Steiner, R. (Co-Investigator), Muller, M. (Co-Investigator), Pfuhl, M. (Co-Investigator), Bergeron, J. (Co-Investigator), Malim, M. (Co-Investigator), Naglik, J. (Co-Investigator), Kampourakis, T. (Co-Investigator), Burgoyne, J. (Co-Investigator), Pastore, A. (Co-Investigator) & De Nicola, G. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/10/2020 → 30/09/2021
Project: Research
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A Bessel beam light sheet microscope
Cox, S. (Primary Investigator), Gautel, M. (Co-Investigator), Parsons, M. (Co-Investigator), Stramer, B. (Co-Investigator), Ehler, E. (Co-Investigator), Oliferenko, S. (Co-Investigator), Eggert, U. (Co-Investigator), Lieberam, I. (Co-Investigator), Habib, S. (Co-Investigator), Srivastava, D. (Co-Investigator), Arnold, J. (Co-Investigator), Carlton, J. (Co-Investigator), Shah, A. (Co-Investigator), Ivetic, A. (Co-Investigator) & Ng, T. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/07/2019 → 30/06/2020
Project: Research
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BHF Research Excellence Award
Shah, A. (Primary Investigator), Botnar, R. (Co-Investigator), Chowienczyk, P. (Co-Investigator), Eaton, P. (Co-Investigator), Garcia-Manyes, S. (Co-Investigator), Gautel, M. (Co-Investigator), Giacca, M. (Co-Investigator), Irving, M. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), Otsu, K. (Co-Investigator), Ourselin, S. (Co-Investigator), Parsons, M. (Co-Investigator), Razavi, R. (Co-Investigator), Schnabel, J. (Co-Investigator), Shanahan, C. (Co-Investigator), Xu, Q. (Co-Investigator) & Phinikaridou, A. (Co-Investigator)
1/04/2019 → 31/03/2024
Project: Research
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Cellular and sub-cellular sampling using laser capture microdissection to understand disease mechanisms
Gautel, M. (Primary Investigator), Ellison, G. (Co-Investigator), Ochala, J. (Co-Investigator), Oakey, R. (Co-Investigator), Zammit, P. (Co-Investigator), Tucker, A. (Co-Investigator), Meyer, M. (Co-Investigator), Knight, R. (Co-Investigator), Green, J. (Co-Investigator) & Shanahan, C. (Co-Investigator)
1/10/2018 → 30/09/2023
Project: Research
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Dissecting the activation mechanism of titin kinase by NMR spectroscopy
Pfuhl, M. (Primary Investigator) & Gautel, M. (Co-Investigator)
1/09/2018 → 3/09/2022
Project: Research
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Sarcomere proteostasis in titinopathies
Gautel, M. (Primary Investigator)
1/04/2018 → 31/03/2023
Project: Research
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AHEAD - The Actin cytoskeleton in striated muscle during HEalth And Disease
Gautel, M. (Primary Investigator)
1/10/2017 → 30/09/2021
Project: Research
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DRIVE - Driving next generation autophagy researchers towards translation
Jungbluth, H. (Primary Investigator) & Gautel, M. (Co-Investigator)
1/10/2017 → 30/04/2022
Project: Research
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Role of prion-like proteins in cell fate and cell memory
Caudron, F. (Primary Investigator) & Gautel, M. (Co-Investigator)
1/09/2017 → 31/08/2022
Project: Research
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When is a titin mutation pathogenic? - Interactions between titin missense and truncating variant in zebrafish
Gautel, M. (Primary Investigator) & academic, A. (Co-Investigator)
1/08/2017 → 31/07/2020
Project: Research
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King’s NMR Facility for structural biology, metabolic profiling and drug discovery
Conte, M. (Primary Investigator), Avkiran, M. (Co-Investigator), Blower, P. (Co-Investigator), Dodding, M. (Co-Investigator), Eaton, P. (Co-Investigator), Gautel, M. (Co-Investigator), Irving, M. (Co-Investigator), Malim, M. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Otsu, K. (Co-Investigator), Pastore, A. (Co-Investigator), Pfuhl, M. (Co-Investigator), Poston, L. (Co-Investigator), Shah, A. (Co-Investigator), Shanahan, C. (Co-Investigator), Shattock, M. (Co-Investigator) & Williamson, C. (Co-Investigator)
BHF British Heart Foundation, Wellcome Trust
1/01/2017 → 31/12/2021
Project: Research
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AHEAD - The Actin cytoskeleton in striated muscle during Health And Disease
Gautel, M. (Primary Investigator)
1/10/2016 → 30/09/2020
Project: Research
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An integrated approach to the muscle Z-disk: from atomic structure to human disease
Gautel, M. (Primary Investigator)
1/09/2016 → 1/10/2021
Project: Research
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Myosin Binding Protein-C: a key regulator of cardiac output
Kampourakis, T. (Primary Investigator), Gautel, M. (Co-Investigator) & Irving, M. (Co-Investigator)
1/03/2016 → 31/03/2020
Project: Research
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Physiological role of RSK-mediated cardiac myosin-binding protein C phosphorylation
Avkiran, M. (Primary Investigator), Gautel, M. (Co-Investigator) & Marber, M. (Co-Investigator)
1/10/2015 → 30/09/2018
Project: Research
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Unravelling the mystery of the hierarchical phosphorylation of MyBP-C and its importance for differential interactions with actin and myosin
Pfuhl, M. (Primary Investigator) & Gautel, M. (Co-Investigator)
1/09/2015 → 31/08/2018
Project: Research
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A comprehensive approach to the genetic, molecular and functional impact of rare titinvariants in hypertrophic cardiomyopathy
Gautel, M. (Primary Investigator), Alexandrovich, A. (Co-Investigator), Fraternali, F. (Co-Investigator) & Rees, M. (Co-Investigator)
1/09/2015 → 30/06/2021
Project: Research
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C-terminal phosphorylation of the sarcomeric Z-disk protein telethonin in the heart: Functional role and molecular mechanisms
Avkiran, M. (Primary Investigator), Gautel, M. (Co-Investigator) & Marber, M. (Co-Investigator)
1/07/2015 → 30/06/2019
Project: Research
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Mechano-regulation of myofibril formation and cardiac remodelling
Gautel, M. (Primary Investigator), Garcia-Manyes, S. (Co-Investigator) & Iskratsch, T. (Co-Investigator)
1/01/2015 → 31/12/2018
Project: Research
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The molecular mechanisms of governing the reversible mechanical folding of cardian titin
Garcia-Manyes, S. (Primary Investigator) & Gautel, M. (Co-Investigator)
1/09/2013 → 31/08/2016
Project: Research
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The molecular mechanisms governing the reversible mechanical folding of cardian titin
Garcia-Manyes, S. (Primary Investigator) & Gautel, M. (Co-Investigator)
1/09/2013 → 31/08/2016
Project: Research
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Secondary pathogenetic mechanisms in XLMTM and CNM
Jungbluth, H. (Primary Investigator) & Gautel, M. (Co-Investigator)
1/07/2013 → 30/06/2016
Project: Research
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Multiparametric advanced fluorescence imaging strategies for in situ analysis of live cell signalling
Irving, M. (Primary Investigator), Ameer-Beg, S. (Co-Investigator), Cox, S. (Co-Investigator), Gautel, M. (Co-Investigator), Geissmann, F. (Co-Investigator), Hughes, S. (Co-Investigator), Jones, G. E. (Co-Investigator), Owen, D. (Co-Investigator), Parsons, M. (Co-Investigator), Ridley, A. (Co-Investigator), Suhling, K. (Co-Investigator) & Watt, F. (Co-Investigator)
1/02/2013 → 12/02/2018
Project: Research
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Muscle Failure and Weakness in Critical Illness: Systems Medicine Approach toPathophysiological Mechanisms, novel Clinical Management and Diagnostics - ICUweak
Gautel, M. (Primary Investigator)
1/01/2013 → 31/12/2016
Project: Research
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Sarcomeric signalling by giant muscle M-band proteins in health and disease
Gautel, M. (Primary Investigator)
1/04/2012 → 30/04/2017
Project: Research
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MURF2: an overlooked nuclear player in cardiac development and remodelling?
Gautel, M. (Primary Investigator) & Mankoo, B. (Primary Investigator)
1/02/2012 → 31/01/2015
Project: Research
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Proteotoxicity: an unappreciated mechanism of heart disease and its potential for novel therapeutics
Gautel, M. (Primary Investigator)
1/10/2011 → 30/09/2017
Project: Research
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The cariac kinome: an unexpected regulatory netwrok with high therapeutic potential - KINOCOR
Gautel, M. (Primary Investigator)
1/09/2011 → 31/08/2015
Project: Research
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The interaction of myosin binding protein C with the myosin regulatory light chain: new leverage to address an old problem
Gautel, M. (Primary Investigator) & Pfuhl, M. (Primary Investigator)
1/01/2011 → 31/12/2013
Project: Research
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The role of Nbr1 and SQSTM1 in striated muscle protein turnover
Gautel, M. (Primary Investigator), Solomon, E. (Co-Investigator) & Whitehouse, C. (Co-Investigator)
1/11/2010 → 31/12/2013
Project: Research
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A structural understanding of how the sarcomeric M-band works and is held together
Gautel, M. (Primary Investigator), Steiner, R. (Primary Investigator) & Rief, M. (Co-Investigator)
1/11/2010 → 31/10/2013
Project: Research
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Muscle Z-disk Protein Complexes: from atomic structure to physiological function: MUZIC
Gautel, M. (Primary Investigator)
1/11/2009 → 31/10/2013
Project: Research
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King's Centre for Biomolecular Spectroscopy
Sutton, B. (Primary Investigator), Conte, M. (Co-Investigator), Drake, A. (Co-Investigator), Gautel, M. (Co-Investigator), McDonnell, J. (Co-Investigator) & Sanderson, M. (Co-Investigator)
1/11/2008 → 30/04/2015
Project: Research
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BHF Chair of Molecular Cardiology
Gautel, M. (Primary Investigator)
1/10/2008 → 30/09/2023
Project: Research
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BHF Centre of Research Excellence
Avkiran, M. (Primary Investigator), Blower, P. (Primary Investigator), Botnar, R. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Eaton, P. (Primary Investigator), Ehler, E. (Primary Investigator), Garcia-Manyes, S. (Primary Investigator), Gautel, M. (Primary Investigator), Geissmann, F. (Primary Investigator), Hussain, M. (Primary Investigator), Irving, M. (Primary Investigator), Kalra, L. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Nagel, E. (Primary Investigator), Otsu, K. (Primary Investigator), Razavi, R. (Primary Investigator), Ridley, A. (Primary Investigator), Shah, A. (Primary Investigator), Shanahan, C. (Primary Investigator), Smith, N. (Primary Investigator), Xu, Q. (Primary Investigator), Alastruey, J. (Co-Investigator), Ameer-Beg, S. (Co-Investigator), Bishop, M. (Co-Investigator), Brain, S. (Co-Investigator), Burgoyne, J. (Co-Investigator), Conte, M. (Co-Investigator), Dhanjal, T. (Co-Investigator), Eminaga, S. (Co-Investigator), Eykyn, T. (Co-Investigator), Gee, T. (Co-Investigator), Heintzmann, R. (Co-Investigator), Hughes, S. (Co-Investigator), Iskratsch, T. (Co-Investigator), Ivetic, A. (Co-Investigator), Jones, G. E. (Co-Investigator), Kentish, J. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Lombardi, G. (Co-Investigator), Mullen, G. (Co-Investigator), Okonko, D. (Co-Investigator), Parsons, M. (Co-Investigator), Pfuhl, M. (Co-Investigator), Phinikaridou, A. (Co-Investigator), Rodaway, A. (Co-Investigator), Shattock, M. (Co-Investigator), Sinkus, R. (Co-Investigator), Springett, R. (Co-Investigator), Steiner, R. (Co-Investigator), Stroud, M. (Co-Investigator), Sun, Y.-B. (Co-Investigator), Wardle, F. (Co-Investigator), Warren, D. (Co-Investigator), Webb, A. (Co-Investigator), Zampetaki, A. (Co-Investigator), Zeng, L. (Co-Investigator) & academic, A. (Co-Investigator)
1/01/2008 → 31/03/2019
Project: Research
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Role of the kinase scaffold Nbr1 in musculoskeletal and regulation of muscle and bone maintenance
Gautel, M. (Primary Investigator), Solomon, E. (Primary Investigator) & Whitehouse, C. (Primary Investigator)
1/01/2008 → 31/12/2010
Project: Research
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Sarcomeric signalling by giant muscle proteins controlling muscle growth and turnover.
Gautel, M. (Primary Investigator)
1/10/2006 → 30/04/2012
Project: Research
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Multi-organismic approach to study normal and aberrant muscle development, function and repair (MYORES)
Dietrich, S. (Primary Investigator), Francis-West, P. (Primary Investigator), Gautel, M. (Primary Investigator), Hughes, S. (Primary Investigator), Mankoo, B. (Primary Investigator) & Zammit, P. (Primary Investigator)
1/01/2005 → 30/06/2010
Project: Research
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Calmodulin regulated protein kinases: molecular and cellular functions of five prototypic members from the human genome by a multidisciplinary approach - CAMKIN
Gautel, M. (Primary Investigator)
1/12/2003 → 31/05/2006
Project: Research
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Pleckstrin domains: allosteric regulation of protein function-new bimolecular tools for structural and biological analysis
Gautel, M. (Primary Investigator)
1/11/2003 → 30/09/2009
Project: Research
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The structure and function of the Mammalian Cytoskeleton - Training Network - CYTONET
Gautel, M. (Primary Investigator)
1/09/2003 → 31/08/2004
Project: Research
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Characterisation of NBR1, a Novel Link of Titin to Stress-Related Signalling in a Muscle
Gautel, M. (Primary Investigator) & Solomon, E. (Primary Investigator)
1/05/2003 → 30/04/2006
Project: Research