King's College London

Research portal

Dr Matthew White

  1. MRI-guided histology of TDP-43 knock-in mice implicates parvalbumin interneuron loss, impaired neurogenesis and aberrant neurodevelopment in amyotrophic lateral sclerosis-frontotemporal dementia

    Lin, Z., Kim, E., Ahmed, M., Han, G., Simmons, C., Redhead, Y., Bartlett, J., Pena Altamira, E., Callaghan, I., White, M., Singh, N., Sawiak, S., Spires-Jones, T., Vernon, A., Coleman, M. P., Green, J., Henstridge, C. M., Davies, J., Cash, D. & Sreedharan, J., 5 Apr 2021, In: Brain Communications. 3, 2, p. FCAB114 20 p.

    Research output: Contribution to journalArticlepeer-review

  2. Protection against oxaliplatin-induced mechanical and thermal hypersensitivity in Sarm1−/− mice

    Gould, S. A., White, M., Wilbrey, A. L., Pór, E., Coleman, M. P. & Adalbert, R., Apr 2021, In: Experimental Neurology. 338, 113607.

    Research output: Contribution to journalArticlepeer-review

  3. Coexistence of perseveration and apathy in the TDP-43Q331K knock-in mouse model of ALS–FTD

    Kim, E., White, M. A., Phillips, B. U., Lopez-Cruz, L., Kim, H., Heath, C. J., Lee, J. E., Saksida, L. M., Sreedharan, J. & Bussey, T. J., 1 Dec 2020, In: Translational psychiatry. 10, 1, 377.

    Research output: Contribution to journalArticlepeer-review

  4. Distinct effects on mRNA export factor GANP underlie neurological disease phenotypes and alter gene expression depending on intron content

    Woldegebriel, R., Kvist, J., Andersson, N., Õunap, K., Reinson, K., Wojcik, M. H., Bijlsma, E. K., Hoffer, M. J. V., Ryan, M. M., Stark, Z., Walsh, M., Cuppen, I., van den Boogaard, M-J. H., Bharucha-Goebel, D., Donkervoort, S., Winchester, S., Zori, R., Bönnemann, C. G., Maroofian, R., O'Connor, E. & 8 others, Houlden, H., Zhao, F., Carpén, O., White, M., Sreedharan, J., Stewart, M., Ylikallio, E. & Tyynismaa, H., 3 Jun 2020, In: Human Molecular Genetics. 29, 9, p. 1426-1439 14 p.

    Research output: Contribution to journalArticlepeer-review

  5. Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS

    Weskamp, K., Tank, E. M., Miguez, R., McBride, J. P., Gómez, N. B., White, M., Lin, Z., Moreno Gonzalez, C., Serio, A., Sreedharan, J. & Barmada, S. J., 2 Mar 2020, In: Journal of Clinical Investigation. 130, 3, p. 1139-1155 17 p.

    Research output: Contribution to journalArticlepeer-review

  6. Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss

    White, M. A., Lin, Z., Kim, E., Henstridge, C. M., Pena Altamira, E., Hunt, C. K., Burchill, E., Callaghan, I., Loreto, A., Brown-Wright, H., Mead, R., Simmons, C., Cash, D., Coleman, M. P. & Sreedharan, J., 28 Oct 2019, (E-pub ahead of print) In: Acta Neuropathologica Communications. 7, 1, p. 1-16 16 p., 166.

    Research output: Contribution to journalArticlepeer-review

  7. TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation

    Howard, L., Wosnitzka, E., Okakpu, D., White, M. A., Wyatt, S. & Davies, A. M., 19 Nov 2018, In: Development. 145, 22

    Research output: Contribution to journalArticlepeer-review

  8. TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD

    White, M. A., Kim, E., Duffy, A., Adalbert, R., Phillips, B. U., Peters, O. M., Stephenson, J., Yang, S., Massenzio, F., Lin, Z., Andrews, S., Segonds-Pichon, A., Metterville, J., Saksida, L. M., Mead, R., Ribchester, R. R., Barhomi, Y., Serre, T., Coleman, M. P., Fallon, J. & 3 others, Bussey, T. J., Brown, R. H. & Sreedharan, J., 19 Mar 2018, In: Nature Neuroscience. 21, p. 552–563

    Research output: Contribution to journalArticlepeer-review

  9. Amyotrophic lateral sclerosis: recent genetic highlights

    White, M. A. & Sreedharan, J., Oct 2016, In: Current Opinion in Neurology. 29, 5, p. 557-64 8 p.

    Research output: Contribution to journalArticlepeer-review

  10. Selective regulation of axonal growth from developing hippocampal neurons by tumor necrosis factor superfamily member APRIL

    Osório, C., Chacón, P. J., White, M., Kisiswa, L., Wyatt, S., Rodríguez-Tébar, A. & Davies, A. M., Mar 2014, In: Molecular and Cellular Neurosciences. 59, p. 24-36 13 p.

    Research output: Contribution to journalArticlepeer-review

  11. Growth differentiation factor 5 is a key physiological regulator of dendrite growth during development

    Osório, C., Chacón, P. J., Kisiswa, L., White, M., Wyatt, S., Rodríguez-Tébar, A. & Davies, A. M., Dec 2013, In: Development (Cambridge): for advances in developmental biology and stem cells. 140, 23, p. 4751-62 12 p.

    Research output: Contribution to journalArticlepeer-review

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