Research output per year
Research output per year
- 150 - 181 out of 181 results
Search results
-
2012
Nerve growth factor gene therapy using adeno-associated viral vectors prevents cardiomyopathy in type 1 diabetic mice
Meloni, M., Descamps, B., Caporali, A., Zentilin, L., Floris, I., Giacca, M. & Emanueli, C., 1 Jan 2012, In: Diabetes. 61, 1, p. 229-240 12 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Neuropilin-1 identifies a subset of bone marrow Gr1-monocytes that can induce tumor vessel normalization and inhibit tumor growth
Carrer, A., Moimas, S., Zacchigna, S., Pattarini, L., Zentilin, L., Ruozi, G., Mano, M., Sinigaglia, M., Maione, F., Serini, G., Giraudo, E., Bussolino, F. & Giacca, M., 15 Dec 2012, In: Cancer Research. 72, 24, p. 6371-6381 11 p.Research output: Contribution to journal › Article › peer-review
49 Citations (Scopus) -
Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer
Bortolussi, G., Zentilin, L., Baj, G., Giraudi, P., Bellarosa, C., Giacca, M., Tiribelli, C. & Muro, A. F., 1 Mar 2012, In: Faseb Journal. 26, 3, p. 1052-1063 12 p.Research output: Contribution to journal › Article › peer-review
73 Citations (Scopus) -
Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice
Maione, F., Capano, S., Regano, D., Zentilin, L., Giacca, M., Casanovas, O., Bussolino, F., Serini, G. & Giraudo, E., 1 May 2012, In: Journal of Clinical Investigation. 122, 5, p. 1832-1848 17 p.Research output: Contribution to journal › Article › peer-review
150 Citations (Scopus) -
Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins
Lovric, J., Mano, M., Zentilin, L., Eulalio, A., Zacchigna, S. & Giacca, M., 1 Jan 2012, In: Molecular Therapy. 20, 11, p. 2087-2097 11 p.Research output: Contribution to journal › Article › peer-review
54 Citations (Scopus) -
VEGF gene therapy: Therapeutic angiogenesis in the clinic and beyond
Giacca, M. & Zacchigna, S., 1 Jun 2012, In: Gene Therapy. 19, 6, p. 622-629 8 p.Research output: Contribution to journal › Review article › peer-review
212 Citations (Scopus) -
Virus-mediated gene delivery for human gene therapy
Giacca, M. & Zacchigna, S., 20 Jul 2012, In: Journal of Controlled Release. 161, 2, p. 377-388 12 p.Research output: Contribution to journal › Review article › peer-review
259 Citations (Scopus) -
2011
A candidate approach implicates the secreted Salmonella effector protein SpvB in P-body disassembly
Eulalio, A., Fröhlich, K. S., Mano, M., Giacca, M. & Vogel, J., 10 Mar 2011, In: PLoS ONE. 6, 3, e17296.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
Erratum: Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle (Gene Therapy (2011) DOI: 10.1038/gt.2011.66)
Karvinen, H., Pasanen, E., Rissanen, T. T., Korpisalo, P., Vähäkangas, E., Jazwa, A., Giacca, M. & Ylä-Herttuala, S., 1 Dec 2011, In: Gene Therapy. 18, 12, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
1 Citation (Scopus) -
Heartening results: The CUPID gene therapy trial for heart failure
Giacca, M. & Baker, A. H., 1 Jul 2011, In: Molecular Therapy. 19, 7, p. 1181-1182 2 p.Research output: Contribution to journal › Editorial › peer-review
8 Citations (Scopus) -
Insulin downregulates SIRT1 and AMPK activation and is associated with changes in liver fat, but not in inflammation and mitochondrial oxidative capacity, in streptozotocin-diabetic rat
Barazzoni, R., Zanetti, M., Sturnega, M., Stebel, M., Semolic, A., Pirulli, A., Vinci, P., Zentilin, L., Giacca, M., Cattin, L. & Guarnieri, G., 1 Jun 2011, In: CLINICAL NUTRITION. 30, 3, p. 384-390 7 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Intravenous gene therapy with PIM-1 via a cardiotropic viral vector halts the progression of diabetic cardiomyopathy through promotion of prosurvival signaling
Katare, R., Caporali, A., Zentilin, L., Avolio, E., Sala-Newby, G., Oikawa, A., Cesselli, D., Beltrami, A. P., Giacca, M., Emanueli, C. & Madeddu, P., 13 May 2011, In: Circulation Research. 108, 10, p. 1238-1251 14 p.Research output: Contribution to journal › Article › peer-review
108 Citations (Scopus) -
Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycle
Di Stefano, V., Giacca, M., Capogrossi, M. C., Crescenzi, M. & Martelli, F., 11 Mar 2011, In: Journal of Biological Chemistry. 286, 10, p. 8644-8654 11 p.Research output: Contribution to journal › Article › peer-review
69 Citations (Scopus) -
Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle
Karvinen, H., Pasanen, E., Rissanen, T. T., Korpisalo, P., Vähäkangas, E., Jazwa, A., Giacca, M. & Ylä-Herttuala, S., 1 Dec 2011, In: Gene Therapy. 18, 12, p. 1166-1172 7 p.Research output: Contribution to journal › Article › peer-review
71 Citations (Scopus) -
Negative regulation of HIV-1 transcription by a heterodimeric NF-κB1/p50 and C-terminally truncated STAT5 complex
Della Chiara, G., Crotti, A., Liboi, E., Giacca, M., Poli, G. & Lusic, M., 29 Jul 2011, In: Journal of Molecular Biology. 410, 5, p. 933-943 11 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Stimulation of cardiac apoptosis in ovariectomized hypertensive rats: Potential role of the renin-angiotensin system
Fabris, B., Candido, R., Bortoletto, M., Toffoli, B., Bernardi, S., Stebel, M., Bardelli, M., Zentilin, L., Giacca, M. & Carretta, R., 1 Feb 2011, In: Journal of Hypertension. 29, 2, p. 273-281 9 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
The TRIM family protein KAP1 inhibits HIV-1 integration
Allouch, A., Di Primio, C., Alpi, E., Lusic, M., Arosio, D., Giacca, M. & Cereseto, A., 16 Jun 2011, In: Cell Host and Microbe. 9, 6, p. 484-495 12 p.Research output: Contribution to journal › Article › peer-review
94 Citations (Scopus) -
Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation
Zhong, X., Huang, H., Shen, J., Zacchigna, S., Zentilin, L., Giacca, M. & Vinores, S. A., 7 Mar 2011, In: Molecular Vision. 17, p. 492-507 16 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
2010
A novel animal model to study non-spontaneous bisphosphonates osteonecrosis of jaw
Biasotto, M., Chiandussi, S., Zacchigna, S., Moimas, S., Dore, F., Pozzato, G., Cavalli, F., Zanconati, F., Contardo, L., Giacca, M. & Di Lenarda, R., 1 Jan 2010, In: Journal of Oral Pathology and Medicine. 39, 5, p. 390-396 7 p.Research output: Contribution to journal › Article › peer-review
62 Citations (Scopus) -
Characterization of a recombinant adeno-associated virus type 2 reference standard material
Lock, M., McGorray, S., Auricchio, A., Ayuso, E., Beecham, E. J., Blouin-Tavel, V., Bosch, F., Bose, M., Byrne, B. J., Caton, T., Chiorini, J. A., Chtarto, A., Clark, K. R., Conlon, T., Darmon, C., Doria, M., Douar, A., Flotte, T. R., Francis, J. D., Francois, A., & 28 others, 1 Oct 2010, In: Human Gene Therapy. 21, 10, p. 1273-1285 13 p.Research output: Contribution to journal › Article › peer-review
112 Citations (Scopus) -
Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes
Manganaro, L., Lusic, M., Gutierrez, M. I., Cereseto, A., Del Sal, G. & Giacca, M., 1 Mar 2010, In: Nature Medicine. 16, 3, p. 329-333 5 p.Research output: Contribution to journal › Article › peer-review
95 Citations (Scopus) -
Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease
Van de Veire, S., Stalmans, I., Heindryckx, F., Oura, H., Tijeras-Raballand, A., Schmidt, T., Loges, S., Albrecht, I., Jonckx, B., Vinckier, S., Van Steenkiste, C., Tugues, S., Rolny, C., De Mol, M., Dettori, D., Hainaud, P., Coenegrachts, L., Contreres, J. O., Van Bergen, T., Cuervo, H., & 30 others, 1 Jan 2010, In: Cell. 141, 1, p. 178-190 13 p.Research output: Contribution to journal › Article › peer-review
237 Citations (Scopus) -
GCN5-dependent acetylation of HIV-1 integrase enhances viral integration
Terreni, M., Valentini, P., Liverani, V., Gutierrez, M. I., Di Primio, C., Di Fenza, A., Tozzini, V., Allouch, A., Albanese, A., Giacca, M. & Cereseto, A., 12 Mar 2010, In: Retrovirology. 7, 18.Research output: Contribution to journal › Article › peer-review
63 Citations (Scopus) -
Gene therapy
Giacca, M., 1 Jan 2010, Springer-Verlag Italia s.r.l. 303 p.Research output: Book/Report › Book › peer-review
9 Citations (Scopus) -
Interaction of the retinoblastoma protein with orc1 and its recruitment to human origins of DNA replication
Mendoza-Maldonado, R., Paolinelli, R., Galbiati, L., Giadrossi, S. & Giacca, M., 9 Dec 2010, In: PLoS ONE. 5, 11, e13720.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy
Pepe, M., Mamdani, M., Zentilin, L., Csiszar, A., Qanud, K., Zacchigna, S., Ungvari, Z., Puligadda, U., Moimas, S., Xu, X., Edwards, J. G., Hintze, T. H., Giacca, M. & Recchia, F. A., 25 Jun 2010, In: Circulation Research. 106, 12, p. 1893-1903 11 p.Research output: Contribution to journal › Article › peer-review
82 Citations (Scopus) -
Nanoparticles from lipid-based liquid crystals: Emulsifier influence on morphology and cytotoxicity
Murgia, S., Falchi, A. M., Mano, M., Lampis, S., Angius, R., Carnerup, A. M., Schmidt, J., Diaz, G., Giacca, M., Talmon, Y. & Monduzzi, M., 18 Mar 2010, In: Journal of Physical Chemistry B. 114, 10, p. 3518-3525 8 p.Research output: Contribution to journal › Article › peer-review
100 Citations (Scopus) -
Non-redundant functions of the protein isoforms arising from alternative splicing of the VEGF-A pre-mRNA
Giacca, M., 1 Jan 2010, In: Transcription. 1, 3, p. 149-153 5 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury
Herrera, J. J., Sundberg, L. M., Zentilin, L., Giacca, M. & Narayana, P. A., 1 Nov 2010, In: Journal of Neurotrauma. 27, 11, p. 2067-2076 10 p.Research output: Contribution to journal › Article › peer-review
57 Citations (Scopus) -
The renaissance of competitive PCR as an accurate tool for precise nucleic acid quantification.
Zentilin, L. & Giacca, M., 1 Jan 2010, In: Methods in molecular biology (Clifton, N.J.). 630, p. 233-248 16 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
2008
Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins
Cervelli, T., Palacios, J. A., Zentilin, L., Mano, M., Schwartz, R. A., Weitzman, M. D. & Giacca, M., 1 Feb 2008, In: Journal of Cell Science. 121, 3, p. 349-357 9 p.Research output: Contribution to journal › Article › peer-review
62 Citations (Scopus)