Melina Hoffmann - Research output - King's College London

759

Citations

6 Article
4 Review article
1 Chapter

11 results

2022
CDK Inhibition Primes for Anti-PD-L1 Treatment in Triple-Negative Breast Cancer Models
Cheung, A., Chenoweth, A. M., Quist, J., Sow, H. S., Malaktou, C., Ferro, R., Hoffmann, R. M., Osborn, G., Sachouli, E., French, E., Marlow, R., Lacy, K. E., Papa, S., Grigoriadis, A. & Karagiannis, S. N., 11 Jul 2022, In: Cancers. 14, 14, 21 p., 3361.
Research output: Contribution to journal › Article › peer-review

Open Access
File
9 Citations (Scopus)

152 Downloads (Pure)
2021
B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies
Willsmore, Z. N., Harris, R. J., Crescioli, S., Hussein, K., Kakkassery, H., Thapa, D., Cheung, A., Chauhan, J., Bax, H. J., Chenoweth, A., Laddach, R., Osborn, G., McCraw, A., Hoffmann, R. M., Nakamura, M., Geh, J. L., MacKenzie-Ross, A., Healy, C., Tsoka, S. & Spicer, J. F. & 4 others, Papa, S., Barber, L., Lacy, K. E. & Karagiannis, S. N., 25 Jan 2021, In: Frontiers in Immunology. 11, 622442.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
45 Citations (Scopus)

181 Downloads (Pure)
Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: treatment of melanoma and immune mechanisms of action
Willsmore, Z. N., Coumbe, B. G. T., Crescioli, S., Reci, S., Gupta, A., Harris, R. J., Chenoweth, A., Chauhan, J., Bax, H. J., McCraw, A., Cheung, A., Osborn, G., Hoffmann, R. M., Nakamura, M., Laddach, R., Geh, J. L. C., Ross, A. M., Healy, C., Tsoka, S. & Spicer, J. F. & 4 others, Josephs, D. H., Papa, S., Lacy, K. E. & Karagiannis, S. N., Mar 2021, In: European Journal of Immunology. 51, 3, p. 544-556 13 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
118 Citations (Scopus)

107 Downloads (Pure)
Translational aspects of biologicals: monoclonal antibodies and antibody-drug conjugates as examples
Karagiannis, S. N., Hoffmann, M., Nakamura, M., Crescioli, S., Bax, H. J., Chenoweth, A., Cheung, A., Tsoka, S., Spicer, J., Lacy, K. E. & Thurston, D., 15 Jul 2021, Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition. Wehling, M. (ed.). 3rd ed. Academic Press, p. 329-350 22 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter
2020
Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)
Hoffmann, R. M., Mele, S., Cheung, A., Larcombe-Young, D., Bucaite, G., Sachouli, E., Zlatareva, I., Morad, H. O. J., Marlow, R., McDonnell, J. M., Figini, M., Lacy, K. E., Tutt, A. J. N., Spicer, J. F., Thurston, D. E., Karagiannis, S. N. & Crescioli, S., 1 Jun 2020, In: Scientific Reports. 10, 1, p. 8869 8869.
Research output: Contribution to journal › Article › peer-review

Open Access
File
13 Citations (Scopus)

84 Downloads (Pure)
Rapid conjugation of antibodies to toxins to select candidates for the development of anti-cancer Antibody-Drug Conjugates (ADCs)
Hoffmann, M., Mele, S., Cheung, A., Larcombe-Young, D., Bucaite, G., Sachouli, E., Zlatareva, I., Morad, H., Marlow, R., McDonnell, J., Figini, M., Lacy, K. E., Tutt, A., Spicer, J., Thurston, D., Karagiannis, S. N. & Crescioli, S., 1 Jun 2020, In: Scientific Reports. 10, 1, 22 p., 8869.
Research output: Contribution to journal › Article › peer-review

Open Access
File
199 Downloads (Pure)
2019
Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma
Khair, D. O., Bax, H. J., Mele, S., Crescioli, S., Pellizzari, G., Khiabany, A., Nakamura, M., Harris, R. J., French, E., Hoffmann, R. M., Williams, I. P., Cheung, K. K. A., Thair, B., Beales, C. T., Touizer, E., Signell, A. W., Tasnova, N. L., Spicer, J. F., Josephs, D. H. & Geh, J. L. C. & 5 others, MacKenzie Ross, A., Healy, C., Papa, S. E., Lacy, K. E. & Karagiannis, S. N., 19 Mar 2019, In: Frontiers in Immunology. MAR, 453.
Research output: Contribution to journal › Article › peer-review

Open Access
File
190 Citations (Scopus)

430 Downloads (Pure)
2018
Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)
Hoffmann, R. M., Coumbe, B. G. T., Josephs, D. H., Mele, S., Ilieva, K. M., Cheung, A., Tutt, A. N., Spicer, J. F., Thurston, D. E., Crescioli, S. & Karagiannis, S. N., 2018, In: OncoImmunology. 7, 3, p. e1395127-e1395127-11 12 p., e1395127.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
139 Citations (Scopus)

523 Downloads (Pure)
Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer
Cheung, A., Opzoomer, J. W., Ilieva, K. M., Gazinska, P., Hoffmann, R. M., Mirza, H., Marlow, R., Francesch-Domenech, E., Fittall, M. W., Dominguez Rodriguez, D., Clifford, A., Badder, L., Patel, N., Mele, S., Pellizzari, G., Bax, H. J., Crescioli, S., Petranyi, G., Larcombe-Young, D. & Josephs, D. H. & 9 others, Canevari, S., Figini, M., Pinder, S. E., Nestle, F. O., Gillett, C., Spicer, J., Grigoriadis, A., Tutt, A. & Karagiannis, S. N., 15 Oct 2018, In: Clinical Cancer Research. 24, 20, p. 5098-5111
Research output: Contribution to journal › Article › peer-review

Open Access
File
69 Citations (Scopus)

254 Downloads (Pure)
2017
BRAF inhibitors: resistance and the promise of combination treatments for melanoma
Griffin, M., Scotto, D., Josephs, D. H., Mele, S., Crescioli, S., Bax, H. J., Pellizzari, G., Wynne, M. D., Nakamura, M., Hoffmann, R. M., Ilieva, K. M., Cheung, A., Spicer, J. F., Papa, S., Lacy, K. E. & Karagiannis, S. N., 2017, In: Oncotarget. 8, 44, p. 78174-78192 19 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
85 Citations (Scopus)

313 Downloads (Pure)
2016
Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome
Woollard, W. J., Pullabhatla, V., Lorenc, A., Patel, V. M., Butler, R. M., Bayega, A., Begum, N., Bakr, F., Dedhia, K., Fisher, J., Aguilar-Duran, S., Flanagan, C., Ghasemi, A. A., Hoffmann, R. M., Castillo-Mosquera, N., Nuttall, E. A., Paul, A., Roberts, C. A., Solomonidis, E. G. & Tarrant, R. & 8 others, Yoxall, A., Beyers, C. Z., Ferreira, S., Tosi, I., Simpson, M. A., de Rinaldis, E., Mitchell, T. J. & Whittaker, S. J., 30 Jun 2016, In: Blood. 127, 26, p. 3387-97 11 p.
Research output: Contribution to journal › Article › peer-review
92 Citations (Scopus)

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