King's College London

Research portal

Professor Michael Malim

Research interests

Professor Malim received his DPhil in Biochemistry from Oxford University in 1987, and was then a post-doctoral fellow at Duke University in North Carolina before joining the faculty at the University of Pennsylvania in 1992. After nine years in Philadelphia, Professor Malim returned to his native U.K. as Professor and Head of the Department of Infectious Diseases.

Professor Malim received an Elizabeth Glaser Pediatric AIDS Foundation Scientist Award in 2001, was awarded the 2010 M Jeang Retrovirology Prize,and was elected as a Fellow of the Academy of Medical Sciences (FMedSci) in 2003, as a Member of the European Molecular Biology Organisation (EMBO) in 2005, and as a Fellow of the Royal Society (FRS) in 2007.

The laboratory utilises molecular genetic, cultured cell, biochemical, structural, bioinformatic and cohort-based methodologies to study the biological principles that underpin HIV replication and pathogenesis (AIDS). Current areas of interest include host-virus interactions, cell-encoded mechanisms of anti-viral resistance and virus particle assembly.

Public lecture/debate/seminar

Nature Publishing Group Conference–Debate on Emerging Infectious Diseases, Fundación Ramón Areces, Madrid

Michael Malim (Contributor), 7 Feb 2013

Activity: Public engagement and outreachPublic lecture/debate/seminar

Café Scientifique, Frisco, CO

Michael Malim (Presenter), 24 Mar 2009

Activity: Public engagement and outreachPublic lecture/debate/seminar

Editorial activity

EMBO REPORTS

Michael Malim (Peer reviewer), 2013 → …

Activity: Editorial work or peer review of publicationsEditorial activity

Virology

Michael Malim (Editor), Sep 2008 → …

Activity: Editorial work or peer review of publicationsEditorial activity

Philosophical Transactions of the Royal Society B

Michael Malim (Editorial board member), 20082013

Activity: Editorial work or peer review of publicationsEditorial activity

PLoS Pathogens

Michael Malim (Editor), 2007 → …

Activity: Editorial work or peer review of publicationsEditorial activity

Cell Host & Microbe

Michael Malim (Editorial board member), 2006 → …

Activity: Editorial work or peer review of publicationsEditorial activity

Reviewing Editors, Science

Michael Malim (Editorial board member), 20062008

Activity: Editorial work or peer review of publicationsEditorial activity

PLoS Pathogens

Michael Malim (Editor), 20052007

Activity: Editorial work or peer review of publicationsEditorial activity

PLoS Pathogens

Michael Malim (Editorial board member), 20052007

Activity: Editorial work or peer review of publicationsEditorial activity

Virology

Michael Malim (Editorial board member), 20022008

Activity: Editorial work or peer review of publicationsEditorial activity

Journal of General Virology

Michael Malim (Editorial board member), 20022006

Activity: Editorial work or peer review of publicationsEditorial activity

Journal of Acquired Immune Deficiency Syndromes

Michael Malim (Editorial board member), 2000 → …

Activity: Editorial work or peer review of publicationsEditorial activity

Molecular and Cellular Biology

Michael Malim (Editorial board member), 19992004

Activity: Editorial work or peer review of publicationsEditorial activity

Journal of Virology

Michael Malim (Editorial board member), 19952006

Activity: Editorial work or peer review of publicationsEditorial activity

Participation in conference

Organising Committee and Speaker, 3rd Frontiers of Retrovirology Conference – Complex Retroviruses, Retroelements and their Hosts, Cambridge

Michael Malim (Member of programme committee), 16 Sep 201318 Sep 2013, Organising Committee and Speaker, 3rd Frontiers of Retrovirology Conference – Complex Retroviruses, Retroelements and their Hosts, Cambridge

Activity: Conference participationParticipation in conference

30 Years of HIV Science: Imagine the Future, Pasteur Institute, Paris

Michael Malim (Invited speaker), 21 May 201323 May 2013, 30 Years of HIV Science: Imagine the Future, Pasteur Institute, Paris

Activity: Conference participationParticipation in conference

Keystone Symposium on Immune Activation in HIV Infection: Basic Mechanisms and Clinical Implications

Michael Malim (Invited speaker), 3 Apr 20137 Apr 2013, Keystone Symposium on Immune Activation in HIV Infection: Basic Mechanisms and Clinical Implications

Activity: Conference participationParticipation in conference

Organiser, Third Crick Symposium, Genetics to Molecules to Therapies, London

Michael Malim (Organiser), 11 Mar 2013, Organiser, Third Crick Symposium, Genetics to Molecules to Therapies, London

Activity: Conference participationParticipation in conference

Second Crick Symposium, Infection and Immunity, London

Michael Malim (Invited speaker), 1 Nov 2012, Second Crick Symposium, Infection and Immunity, London

Activity: Conference participationParticipation in conference

Keynote Speaker; International Meeting on Molecular Biology of Hepatitis B Viruses, Oxford

Michael Malim (Keynote/plenary speaker), 22 Sep 2012, Keynote Speaker; International Meeting on Molecular Biology of Hepatitis B Viruses, Oxford

Activity: Conference participationParticipation in conference

ANRS Basic Research Symposium on HIV and Hepatitis Viruses Replication, Pasteur Institute, Paris

Michael Malim (Invited speaker), 2 May 2012, ANRS Basic Research Symposium on HIV and Hepatitis Viruses Replication, Pasteur Institute, Paris

Activity: Conference participationParticipation in conference

Fifth Annual Meeting of the Cambridge Retrovirologists

Michael Malim (Invited speaker), 26 Jan 2012, Fifth Annual Meeting of the Cambridge Retrovirologists

Activity: Conference participationParticipation in conference

Twelfth NCI/DRP Symposium on Antiviral Drug Resistance, Hershey, PA

Michael Malim (Invited speaker), 5 Nov 20119 Nov 2011, Twelfth NCI/DRP Symposium on Antiviral Drug Resistance, Hershey, PA

Activity: Conference participationParticipation in conference

Frontiers of Retrovirology, Amsterdam

Michael Malim (Invited speaker), 3 Oct 20115 Oct 2011, Frontiers of Retrovirology, Amsterdam

Activity: Conference participationParticipation in conference

Gordon Research Conference on RNA Editing, Galveston, TX

Michael Malim (Invited speaker), 9 Jan 201113 Jan 2011, Gordon Research Conference on RNA Editing, Galveston, TX

Activity: Conference participationParticipation in conference

EMBO Meeting, At the joint edge of Cellular Microbiology & Cell Biology, Kraków

Michael Malim (Invited speaker), 9 Oct 201013 Oct 2010, EMBO Meeting, At the joint edge of Cellular Microbiology & Cell Biology, Kraków

Activity: Conference participationParticipation in conference

Cambridge Immunology Forum on Innate Immunity and Viral Evasion

Michael Malim (Invited speaker), 23 Sep 2010, Cambridge Immunology Forum on Innate Immunity and Viral Evasion

Activity: Conference participationParticipation in conference

Symposium on Principles of Molecular Biology, Pathogenesis and Control of Human Viruses, Zurich

Michael Malim (Invited speaker), 15 Sep 201017 Sep 2010, Symposium on Principles of Molecular Biology, Pathogenesis and Control of Human Viruses, Zurich

Activity: Conference participationParticipation in conference

Centennial Retrovirus Meeting, Prague

Michael Malim (Invited speaker), 29 Apr 20102 May 2010, Centennial Retrovirus Meeting, Prague

Activity: Conference participationParticipation in conference

Keystone Symposium on HIV Biology and Pathogenesis

Michael Malim (Invited speaker), 11 Jan 201015 Jan 2010, Keystone Symposium on HIV Biology and Pathogenesis

Activity: Conference participationParticipation in conference

13th Annual Resistance Meeting, London

Michael Malim (Invited speaker), Sep 2009, 13th Annual Resistance Meeting, London

Activity: Conference participationParticipation in conference

Keystone Symposium on HIV Immunobiology

Michael Malim (Invited speaker), Mar 2009, Keystone Symposium on HIV Immunobiology

Activity: Conference participationParticipation in conference

New Investigators and Trainees at 16th Conference on Retroviruses & Opportunistic Infections, Montreal

Michael Malim (Invited speaker), Feb 2009, New Investigators and Trainees at 16th Conference on Retroviruses & Opportunistic Infections, Montreal

Activity: Conference participationParticipation in conference

Plenary Speaker, XIV International Congress of Virology, Istanbul

Michael Malim (Keynote/plenary speaker), Aug 2008, Plenary Speaker, XIV International Congress of Virology, Istanbul

Activity: Conference participationParticipation in conference

Royal Society Discussion Meeting on DNA Deamination in Immunity, Virology and Cancer, London

Michael Malim (Invited speaker), Jun 2008, Royal Society Discussion Meeting on DNA Deamination in Immunity, Virology and Cancer, London

Activity: Conference participationParticipation in conference

Meeting Organiser, 25 Years of HIV, Pasteur Institute, Paris

Michael Malim (Organiser), May 2008, Meeting Organiser, 25 Years of HIV, Pasteur Institute, Paris

Activity: Conference participationParticipation in conference

25 Years of HIV, Pasteur Institute, Paris

Michael Malim (Invited speaker), May 2008, 25 Years of HIV, Pasteur Institute, Paris

Activity: Conference participationParticipation in conference

Keystone Symposium on Cell Biology of Virus Entry, Replication and Pathogenesis

Michael Malim (Invited speaker), Apr 2008, Keystone Symposium on Cell Biology of Virus Entry, Replication and Pathogenesis

Activity: Conference participationParticipation in conference

Keystone Symposium on Molecular Mechanisms of HIV Pathogenesis

Michael Malim (Invited speaker), Mar 2008, Keystone Symposium on Molecular Mechanisms of HIV Pathogenesis

Activity: Conference participationParticipation in conference

EMBO Conference on Infectious Diseases, Pasteur Institute, Paris

Michael Malim (Invited speaker), Nov 2007, EMBO Conference on Infectious Diseases, Pasteur Institute, Paris

Activity: Conference participationParticipation in conference

Genetics and mechanisms of susceptibility to infectious diseases

Michael Malim (Organiser), Sep 2007, Genetics and mechanisms of susceptibility to infectious diseases

Activity: Conference participationParticipation in conference

ELSO 2007 Conference, Dresden

Michael Malim (Invited speaker), Sep 2007, ELSO 2007 Conference, Dresden

Activity: Conference participationParticipation in conference

MRC Showcase – Investigating Infection & Immunity, Birmingham

Michael Malim (Invited speaker), Apr 2007, MRC Showcase – Investigating Infection & Immunity, Birmingham

Activity: Conference participationParticipation in conference

Lead Organiser, Keystone Symposium on HIV Pathogenesis

Michael Malim (Chair), Mar 2007, Lead Organiser, Keystone Symposium on HIV Pathogenesis

Activity: Conference participationParticipation in conference

Plenary Speaker, 29th Annual Zürich Symposium on Infectious Diseases, Swiss Society for Infectious Diseases

Michael Malim (Keynote/plenary speaker), Mar 2007, Plenary Speaker, 29th Annual Zürich Symposium on Infectious Diseases, Swiss Society for Infectious Diseases

Activity: Conference participationParticipation in conference

New Investigator Workshop at 14th Conference on Retroviruses & Opportunistic Infections, Los Angeles, CA

Michael Malim (Invited speaker), Feb 2007, New Investigator Workshop at 14th Conference on Retroviruses & Opportunistic Infections, Los Angeles, CA

Activity: Conference participationParticipation in conference

Almroth Wright Lecture on “APOBEC Proteins, Cytidine Deamination and Intrinsic Resistance to HIV Infection”, Imperial College, London

Michael Malim (Invited speaker), 2006 → …, Almroth Wright Lecture on “APOBEC Proteins, Cytidine Deamination and Intrinsic Resistance to HIV Infection”, Imperial College, London

Activity: Conference participationParticipation in conference

Cold Spring Harbor Meeting on Retroviruses

Michael Malim (Keynote/plenary speaker), 2006 → …, Cold Spring Harbor Meeting on Retroviruses

Activity: Conference participationParticipation in conference

10th Annual Bernard Fields Memorial Lecture, “Natural Resistance to HIV Infection: the Vif-APOBEC Interaction”

Michael Malim (Invited speaker), 2005 → …, 10th Annual Bernard Fields Memorial Lecture, “Natural Resistance to HIV Infection: the Vif-APOBEC Interaction”

Activity: Conference participationParticipation in conference

Co-Organiser, Keystone Symposium on HIV Pathogenesis

Michael Malim (Organiser), 2005 → …, Co-Organiser, Keystone Symposium on HIV Pathogenesis

Activity: Conference participationParticipation in conference

Plenary Speaker, 16th Annual Australasian Society for HIV Medicine (ASHM) Conference, Canberra Keynote Speaker 44th Interscience Conference on Antimicrobial Agents & Chemotherapy (ICAAC), Washington DC

Michael Malim (Keynote/plenary speaker), 2004 → …, Plenary Speaker, 16th Annual Australasian Society for HIV Medicine (ASHM) Conference, Canberra Keynote Speaker 44th Interscience Conference on Antimicrobial Agents & Chemotherapy (ICAAC), Washington DC

Activity: Conference participationParticipation in conference

Co-Organiser, Keystone Symposium on HIV Pathogenesis

Michael Malim (Organiser), 2004 → …, Co-Organiser, Keystone Symposium on HIV Pathogenesis

Activity: Conference participationParticipation in conference

Plenary Speaker 10th Conference on Retroviruses & Opportunistic Infections (CROI), Boston

Michael Malim (Keynote/plenary speaker), 2003 → …, Plenary Speaker 10th Conference on Retroviruses & Opportunistic Infections (CROI), Boston

Activity: Conference participationParticipation in conference

the Conference on Retroviruses and Opportunistic Infections

Michael Malim (Organiser), 2001 → …, the Conference on Retroviruses and Opportunistic Infections

Activity: Conference participationParticipation in conference

Membership of peer review panel or committee

Royal Society/Wellcome Trust Sir Henry Dale Fellowship Interview Committee

Michael Malim (Member), 2012 → …

Activity: External academic engagementMembership of peer review panel or committee

MRC Institute Review Committee, National Institute for Medical Research

Michael Malim (Member), 31 Aug 20111 Sep 2011

Activity: External academic engagementMembership of peer review panel or committee

MRC Subcommittee, Review of Cell Biology Unit at UCL

Michael Malim (Member), 18 Jul 201119 Jul 2011

Activity: External academic engagementMembership of peer review panel or committee

MRC Infections and Immunity Research Board

Michael Malim (Member), 20092013

Activity: External academic engagementMembership of peer review panel or committee

Reviewer for the Royal Society's International Conference Grants & Short Visits, Panel 6: Biochemistry

Michael Malim (Member), 2001 → …

Activity: External academic engagementMembership of peer review panel or committee

Ad hoc reviewer, EMBO

Michael Malim (Member), 2001 → …

Activity: External academic engagementMembership of peer review panel or committee

Ad hoc reviewer, Wellcome Trust

Michael Malim (Member), 2001 → …

Activity: External academic engagementMembership of peer review panel or committee

Invited talk

Distinguished Lecturer; Fox Chase Cancer Center, Philadelphia

Michael Malim (Speaker), 12 Feb 2009

Activity: External academic engagementInvited talk

Work on advisory panel to industry or government or non-government organisation

External Scientific Advisory Board, MRC Centre for Virus Research, Glasgow

Michael Malim (Member), 2013 → …

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Scientific Advisory Board, Institut Cochin, Paris

Michael Malim (Member), 2011 → …

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Scientific Advisory Board, MRC Centre for Medical Molecular Virology, University College London

Michael Malim (Member), 2011 → …

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Scientific Advisory Committee, Division of Microbiology at the New England Primate Research Center, Harvard University

Michael Malim (Advisor), Jun 2009

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Drucker Laboratory for Infectious Diseases, Northwestern University

Michael Malim (Advisor), Oct 2008 → …

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Viracept EMS Toxicology Expert Panel for F. Hoffman-La Roche Ltd

Michael Malim (Member), May 2008

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Pfizer's Infectious Disease Therapeutic Area Scientific Advisory Panel (TASAP)

Michael Malim (Advisor), 20082010

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Gladstone Institute of Virology and Immunology

Michael Malim (Advisor), 2006 → …

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Gladstone Institute of Virology and Immunology

Michael Malim (Advisor), 2006

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

OyaGen Inc

Michael Malim (Advisor), 20052009

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

OyaGen Inc

Michael Malim (Advisor), 2005 → …

Activity: Business and communityWork on advisory panel to industry or government or non-government organisation

Election to learned society

Fellowship of King’s College London (FKC)

Michael Malim (Recipient), 2013 → …

Activity: AwardsElection to learned society

Elected to Fellow of the Royal Society (FRS)

Michael Malim (Recipient), 2007 → …

Activity: AwardsElection to learned society

Elected to Fellow of the American Academy of Microbiology

Michael Malim (Recipient), 2005 → …

Activity: AwardsElection to learned society

Member of the European Molecular Biology Organisation (EMBO)

Michael Malim (Recipient), 2005 → …

Activity: AwardsElection to learned society

Elected to Fellow of the Academy of Medical Sciences

Michael Malim (Recipient), 2003 → …

Activity: AwardsElection to learned society

Publication peer-review

Review for many scientific journals, both disciplinary and inter-disciplinary (e.g., Nature, Cell, Science)

Michael Malim (Editor), 2001 → …

Activity: Editorial work or peer review of publicationsPublication peer-review

Honorary degree

DSc honoris causa, University of Bristol

Michael Malim (Recipient), 13 Jul 2010

Activity: AwardsHonorary degree

Prize (including medals and awards)

Fourth Annual Joklik Distinguished Lectureship; Duke University

Michael Malim (Recipient), 7 Sep 2013

Activity: AwardsPrize (including medals and awards)

Ninth Annual Neal Nathanson Lectureship; University of Pennsylvania

Michael Malim (Recipient), 22 Jun 2011

Activity: AwardsPrize (including medals and awards)

Sir Michael Stoker CVR Award Lecture; MRC-University of Glasgow Centre for Virus Research

Michael Malim (Recipient), 1 Jun 2011

Activity: AwardsPrize (including medals and awards)

M Jeang Retrovirology Prize

Michael Malim (Recipient), 2010

Activity: AwardsPrize (including medals and awards)

Graduate School Supervisory Excellence Award, King’s College London

Michael Malim (Recipient), 2010

Activity: AwardsPrize (including medals and awards)

Membership of external research organisation

the American Academy of Microbiology

Michael Malim (Fellow), 2005 → …

Activity: External academic engagementMembership of external research organisation

the European Molecular Biology Organisation (EMBO)

Michael Malim (Member), 2005 → …

Activity: External academic engagementMembership of external research organisation

the Academy of Medical Sciences

Michael Malim (Fellow), 2003 → …

Activity: External academic engagementMembership of external research organisation

refer to "august bodies

Michael Malim (Member), 2001 → …

Activity: External academic engagementMembership of external research organisation

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