Search results

• 2010

  A2UCOE Lentiviral Vector Resists DNA Methylation-Mediated Silencing, Conferring Long-Term Expression in HSCs Following Serial Transplantation In Vivo

  Zhang, F., Antoniou, M. N. & Thrasher, A., 2010, In: Human Gene Therapy. 21, 4, p. 514 - 515 2 p.

  Research output: Contribution to journal › Meeting abstract

• Conditional Expansion of Human Skeletal Muscle Satellite Cells by the Tamoxifen-Inducible c-mycERTAM Fusion Protein Following Lentiviral Vector Transduction for Cell Therapy Purposes

  Rossi, C. A., Campanella, M., Zia, S., Leclere, P., Rapisarda, C., Pierro, A., Antoniou, M. & De Coppi, P., 2010, In: Human Gene Therapy. 21, 4, p. 523 - 523 1 p.

  Research output: Contribution to journal › Meeting abstract

• Congenic Fetal Delivered Lentivirus UCOE-Luciferase Transduced Amniotic Fluid Stem Cells Preferentially Engraft in the Liver

  Shaw, S. W. S., David, A. L., Antoniou, M., Meola, M., Ward, N., De Coppi, P. & Waddington, S. N., 2010, In: Human Gene Therapy. 21, 4, p. 522 - 522 1 p.

  Research output: Contribution to journal › Meeting abstract

• Development of In Utero Lentiviral Vector Gene Therapy Approaches for Inherited Diseases

  Ferreira, S., Kao, V., Waddington, S., Ward, N., Thrasher, A. J. & Antoniou, M. N., 2010, In: Human Gene Therapy. 21, 4, p. 524 - 524 1 p.

  Research output: Contribution to journal › Meeting abstract

• Evaluation of Several DNA Expression Constructs for the Level and Longevity of Expression of the Pancreatic Transcription Factor pdx1 in Rat Liver

  Cim, A., Sawyer, G. J., Zhang, H., Su, H., Collins, L., Antoniou, M., Lipps, H. & Fabre, J. W., 2010, In: Human Gene Therapy. 21, 4, p. 517 - 517 1 p.

  Research output: Contribution to journal › Meeting abstract

• Insertional Mutagenesis by Lentiviral Vectors

  Knight, S. B., Bokhoven, M., Gubta, A., Zhang, F., Antoniou, M., Thrasher, A., Collins, M. & Takeuchi, Y., 2010, In: Human Gene Therapy. 21, 4, p. 496 - 497 2 p.

  Research output: Contribution to journal › Meeting abstract

• Nonviral Delivery of the Rat PDX1 Gene to Rat Liver For the In Vivo Transdifferentiation of Liver Cells to Pancreatic Beta-Cells

  Cim, A., Sawyer, G., Zhang, X., Su, H., Collins, L., Jones, P., Antoniou, M., Lipps, H. J. & Fabre, J., 2010, In: Human Gene Therapy. 21, 9, p. 1182 - 1182 1 p.

  Research output: Contribution to journal › Meeting abstract

• Systemic Gene Therapy of SCID-ADA: Improving Transgene Expression in the Erythrocyte Lineage

  Montiel-Equihua, C. A., Antoniou, M., Thrasher, A. J. & Gaspar, H. B., 2010, In: Human Gene Therapy. 21, 4, p. 497 - 497 1 p.

  Research output: Contribution to journal › Meeting abstract

• TREATMENT OF COLLAGEN-INDUCED ARTHRITIS WITH LENTIVIRAL BIP IMPROVES CLINICAL PARAMETERS OF DISEASE

  Shields, A. M., Wooley, P. H., Thompson, S. J., Klavinskis, L. S., Panayi, G. S., Antoniou, M. & Corrigall, V. M., 2010, In: Annals of the Rheumatic Diseases. 69

  Research output: Contribution to journal › Meeting abstract
• 2009

  Lentiviral Gene Therapy Strategies for the Nuclear Protein Aggregation Disorder Oculopharyngeal Muscular Dystrophy (OPMD)

  Bales, O., Trollet, C., van der Maarel, S., Dickson, G. & Antoniou, M. N., 2009, In: Molecular Therapy. 17, p. S363 - S363

  Research output: Contribution to journal › Meeting abstract

• Oculopharyngeal muscular dystrophy (OPMD): Physiopathological mechanisms and gene therapy approaches

  Trollet, C., Bales, O., Anvar, Y., Foster, K., Mamchaoui, K., 't Hoen, P. A., Raz, V., van der Maarel, S., Antoniou, M., Mouly, V., Butler-Browne, G. & Dickson, G., 2009, In: Neuromuscular Disorders. 19, 8-9, p. 579 - 579 1 p.

  Research output: Contribution to journal › Meeting abstract

• Ubiquitous Chromatin Opening Element (UCOE)-Driven Transgenes within Lentiviral Vectors Are Not Subject to DNA Methylation Mediated Silencing

  Zhang, F., Antoniou, M. N. & Thrasher, A. J., 2009, In: Molecular Therapy. 17, p. S161 - S161

  Research output: Contribution to journal › Meeting abstract
• 2008

  A comparative study for efficient transgene expression from non-integrating lentiviral vectors

  Ferreira, S., Leclere, P., Kao, V., Talbot, G. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 4, p. 420 - 420 1 p., 81.

  Research output: Contribution to journal › Meeting abstract

• An enhancer-less ubiquitous chromatin opening element (UCOE) provides highly reproducible and stable transgene expression in haematopoietic cells.

  Antoniou, M., Zhang, F. & Adrian, T., 2008, In: Molecular Therapy. 16, p. S382 - S382

  Research output: Contribution to journal › Meeting abstract

• Comparative analysis of UCOE-based lentiviral vectors in a murine neonatal intravascular delivery system

  Ferreira, S., Waddington, S. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 10, p. 1202 - 1202 1 p.

  Research output: Contribution to journal › Meeting abstract

• Evaluation of self-inactivating lentiviral vectors containing myeloid specific promoters in combination with the ubiquitously acting chromatin opening element (UCOE) for gene therapy of X-CGD

  Santilli, G., Blundell, M., Haria, S., Kinnon, C., Antoniou, M., Grez, M. & Thrasher, A., 2008, In: Human Gene Therapy. 19, 4, p. 417 - 417 1 p., 72.

  Research output: Contribution to journal › Meeting abstract

• Expression and siRNA targeting of PABPN1 as a model for oculopharyngeal muscular dystrophy (OPMd)

  Trollet, C., Benstead, J., Graham, I., Yanez, R., Antoniou, M. & Dickson, G., 2008, In: Human Gene Therapy. 19, 4, p. 420 - 420 1 p., 80.

  Research output: Contribution to journal › Meeting abstract

• Expression and siRNA targeting of PABPN1 as a model for oculopharyngeal muscular dystrophy (OPMD)

  Trollet, C., Benstead, J., Graham, I., Yanez, R., Antoniou, M. & Dickson, G., 2008, In: Neuromuscular Disorders. 18, 9-10, p. 799 - 799 1 p.

  Research output: Contribution to journal › Meeting abstract

• Gene therapy strategy for occulopharyngeal muscular dystrophy (OPMD)

  Trollet, C., Benstead, J., Bales, O., Foster, H., Graham, I., Butler-Browne, G., Antoniou, M. & Dickson, G., 2008, In: Human Gene Therapy. 19, 10, p. 1080 - 1081 2 p.

  Research output: Contribution to journal › Meeting abstract
  4 Citations (Scopus)

• Insertional mutagenesis by retroviral and lentiviral vectors

  Knight, S., Bokhoven, M., Gupta, A., Ceylan, M., Zhang, F., Antoniou, M., Thrasher, A., Takeuchi, Y. & Collins, M., 2008, In: Human Gene Therapy. 19, 10, p. 1190 - 1190 1 p.

  Research output: Contribution to journal › Meeting abstract

• Lentiviral-based gene therapy for oculopharyngeal muscular dystrophy

  Bales, O., Yanez, R., Talbot, G., van der Maarel, S. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 4, p. 415 - 415 1 p., 64.

  Research output: Contribution to journal › Meeting abstract

• Lentiviral-based gene therapy for oculopharyngeal muscular dystrophy

  Bales, O., Yanez, R., Talbot, G., Trollet, C., Dickson, G., van der Maarel, S. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 10, p. 1177 - 1177 1 p.

  Research output: Contribution to journal › Meeting abstract

• Lentiviral vectors for gene-therapy of X-CGD: specific and high expression of gp91phox restricted to granulocytes

  Brendel, C., Stein, S., Antoniou, M. & Grez, M., 2008, In: Human Gene Therapy. 19, 10, p. 1132 - 1132 1 p.

  Research output: Contribution to journal › Meeting abstract

• Lentiviral vectors transduce human skeletal myoblasts with a far greater efficiency than murine myoblasts

  Bales, O., Leclere, P., Lecomte, M., Dickson, G. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 10, p. 1177 - 1178 2 p.

  Research output: Contribution to journal › Meeting abstract

• Novel lentiviral vectors for haemophilia gene therapy

  Kao, V., Waddington, S., Thrasher, A. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 10, p. 1134 - 1134 1 p.

  Research output: Contribution to journal › Meeting abstract

• Novel lentiviral vectors for targeting the red blood cell lineage

  Kao, V., Waddington, S., Thrasher, A. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 4, p. 415 - 415 1 p., 63.

  Research output: Contribution to journal › Meeting abstract

• Tissue specific expression from integration deficient lentiviral vectors

  Ferreira, S., Leclere, P., Kao, V., Talbot, G., Bales, O. & Antoniou, M., 2008, In: Human Gene Therapy. 19, 10, p. 1200 - 1200 1 p.

  Research output: Contribution to journal › Meeting abstract

• Ubiquitous chromatin opening element (UCOE)-driven transgenes within lentiviral vectors are not subject to DNA methylation mediated silencing

  Zhang, F., Antoniou, M. & Thrasher, A., 2008, In: Human Gene Therapy. 19, 10, p. 1093 - 1093 1 p.

  Research output: Contribution to journal › Meeting abstract

  5 Citations (Scopus)

• UCOE (ubiquitous chromatin opening element) mediates copy dependent expression of gp91phox in lentiviral vectors

  Brendel, C., Stein, S., Antoniou, M. & Grez, M., 2008, In: Blood Cells Molecules and Diseases. 40, 2, p. 257 - 258 2 p., 15.

  Research output: Contribution to journal › Meeting abstract
• 2007

  A lentiviral vector containing a chromatin opening element mediates high, persistent, and copy-dependent expression of gp91(phox)

  Brendel, C., Stein, S., Antoniou, M. & Grez, M., 2007, In: Human Gene Therapy. 18, 10, p. 1038 - 1039 2 p.

  Research output: Contribution to journal › Meeting abstract

• A novel UCOE promoter provides reproducible and stable transgene expression

  Zhang, F., Thornhill, S., Howe, S. J., Schambach, A., Gaspar, B., Kinnon, C., Antoniou, M. & Thrasher, A., 2007, In: Human Gene Therapy. 18, 10, p. 990 - 990 1 p.

  Research output: Contribution to journal › Meeting abstract

• Expression and siRNA targeting of PABPN1 as a model for oculopharyngeal muscular dystrophy

  Trollet, C., Benstead, J., Foster, H., Graham, I., Yanez-Munoz, R. J., Antoniou, M. & Dickson, G., 2007, In: Human Gene Therapy. 18, 10, p. 986 - 986 1 p.

  Research output: Contribution to journal › Meeting abstract

• Gene expression profiling in a skeletal muscle cell model of oculopharyngeal muscular dystrophy reveals an extracellular matrix defect

  Sterrenburg, E., Routledge, S., van der Sluijs, B., van der Wees, C., van Engelen, B., Antoniou, M. & van der Maarel, S., 2007, In: Neuromuscular Disorders. 17, 9-10, p. 809 - 809 1 p., G.P.7.13.

  Research output: Contribution to journal › Meeting abstract
• 2006

  Gene therapy for beta thalassemia: preclinical studies on human cells.

  Roselli, EA., Cesari, R., Miccio, A., Tiboni, F., Corbella, P., Rossi, C., Biral, E., Marktel, S., Antoniou, M., Andreani, M., Lucarelli, G. & Ferrari, G., 2006, In: Molecular Therapy. 13, p. S257 - S257 667.

  Research output: Contribution to journal › Meeting abstract

• Long term correction of beta-thalassemia by transplantation of transduced hematopoietic stem cells.

  Miccio, A., Cesari, R., Lotti, F., Rossi, C., Tiboni, F., Sanvito, F., Ponzoni, M., Routledge, S., Antoniou, M. & Ferrari, G., 2006, In: Molecular Therapy. 13, p. S30 - S30 70.

  Research output: Contribution to journal › Meeting abstract
• 2005

  Gene expression profiling reveals a new molecular pathway involved in oculopharyngeal muscular dystrophy.

  Sterrenburg, E., Routledge, S. J. E., van der Sluijs, B. M., van Engelen, B. G., Antoniou, M. & van der Maarel, S. M., 2005, In: Neuromuscular Disorders. 15, 9-10, p. 708 - 708 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2002

  Genomic characterisation of the human prion protein (PrP) gene locus

  Makrinou, E., Antoniou, M., Collinge, J. & Collinge, J., 2002, In: European Journal of Human Genetics. 10, p. 168 - 168 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2001

  Genomic characterisation of the human PRNP/PRND locus.

  Makrinou, E., Collinge, J. & Antoniou, M., 2001, In: American Journal of Human Genetics. 69, 4, p. 369 - 369 1 p.

  Research output: Contribution to journal › Meeting abstract