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Michael Curtis

Dr

  • Phone020 7188 1095
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Personal profile

Research interests

Our research is focused on sudden cardiac death. We have developed several animal models for studying ventricular arrhythmias, the effects of drugs, and the effects of transgenic target modification. Our aim is simple: to identify the best ways of targeting the pathology and its associated electrophysiological dysfunction that causes cardiac arrhythmias during ischaemic heart disease - still the single largest cause of death in the UK population. We are strong proponents of bioassay, generation of clinically-relevant animal models, and pharmacological interrogation of drug action (concentration-response analysis). We work as a small team, engaging with other teams to pursue specific goals. We are keen to collaborate with the pharmaceutical industry in translational drug discovery research, and also have an interest in safety pharmacology, particularly the development of models for detecting drug-induced torsades de pointes (proarrhythmia).

Research interests (short)

Cardiac arrhythmias; antiarrhythmic drugs; ischaemic heart disease; torsades de pointes; coronary control.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water

External positions

External Examiner University of Dundee, University of Dundee

1 Sept 20211 Sept 2024

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