Research output per year
Research output per year
Personal profile
Research interests
Regulation and function of ion translocating proteins in cardiac muscle in health and disease. Current research focuses on the regulation of the cardiac Na/K ATPase by its accessory protein phospholemman.
Research interests (short)
Regulation and function of ion translocating proteins in cardiac muscle in health and disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Disrupting Na+ ion homeostasis and Na+/K+ ATPase activity in breast cancer cells directly modulates glycolysis in vitro and in vivo.
Michaels, A. M., Zoccarato, A., Hoare, Z., Firth, G., Chung, Y. J., Kuchel, P. W., Shah, A. M., Shattock, M. J., Southworth, R. & Eykyn, T. R., 24 May 2024, In: Cancer & metabolism. 12, 1, p. 15Research output: Contribution to journal › Article › peer-review
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Elevated Na is a dynamic and reversible modulator of mitochondrial metabolism in the heart: Intracellular Na reversibly alters myocardial metabolism and energetics
Chung, Y. J., Hoare, Z., Baark, F., Yu, C. S., Gun, J., Fuller, W., Southworth, R., Katschinski, D. M., Murphy, M. P., Eykyn, T. & Shattock, M., 20 May 2024, In: Nature Communications. 15, 1, 4277.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of a novel cardiac-specific myosin modulator using artificial intelligence-based virtual screening
Parijat, P., Attili, S., Hoare, Z., Shattock, M., Kenyon, V. & Kampourakis, T., 13 Nov 2023, In: Nature Communications.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)135 Downloads (Pure) -
Empagliflozin improves cardiac energetics during ischaemia/reperfusion by directly increasing cardiac ketone utilization: EMPA increases cardiac ketone utilisation independent of supply
Chase, D., Eykyn, T. R., Shattock, M. J. & Chung, Y. J., Nov 2023, In: Cardiovascular Research. 119, 16, p. 2672-2680 9 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Dynamic but discordant alterations in zDHHC5 expression and palmitoylation of its substrates in cardiac pathologies
Main, A., Boguslavskyi, A., Howie, J., Kuo, C. W., Rankin, A., Burton, F. L., Smith, G. L., Hajjar, R., Baillie, G. S., Campbell, K. S., Shattock, M. J. & Fuller, W., 5 Oct 2022, In: Frontiers in Physiology. 13, 1023237.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus)
Projects
- 45 Finished
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The Virtual Rat Heart Bioassay
Niederer, S., Curtis, M. & Shattock, M.
2/10/2017 → 1/10/2020
Project: Research
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The Na/K ATPase in cardiovascular health and disease
Shattock, M., Aksentijevic, D., Basalay, M. & Tokar, S.
1/10/2017 → 30/06/2022
Project: Research
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Targeting the repair and regeneration of the damaged and aged heart
Ellison, G., Oakey, R. & Shattock, M.
1/05/2017 → 30/04/2022
Project: Research
Activities
- 1 Types of External academic engagement - Membership of external research organisation
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European Society of Cardiology (ESC) Working Groups on Cellular Biology
Michael Shattock (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation