Research output per year
Research output per year
Personal profile
Research interests
My interests lie in the development of new methods for the analysis of genetic data, with various fields of application ranging from medicine to forensics to genetic history. Of particular interest to me is the analysis of large-scale association data, either via genomewide SNP chips or via Next Generation Sequencing. I also work on population genetic questions arising from these genomewide data, such as the ability to query one's biogeographic origins based on one's DNA alone. Other research include data integration, gene-gene and genome-genome interaction, forensics, expression QTLs and selection.
Research interests (short)
Statistical genetics; genetic epidemiology; population genetics
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Master of Science, Biometry (with Distinction), University of Reading
Award Date: 1 Jan 1998
Doctor of Philosophy, Degrees of Visible Polymorphism and New Methods for Measuring Frequency-Dependent Selection by Predators, University of Southampton
Award Date: 1 Jan 1992
Bachelor of Science, Biology with Computer Studies, University of Southampton
Award Date: 1 Jan 1987
Fingerprint
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- 1 Similar Profiles
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Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals: Genomic Precision Medicine May Dispense With Ethnicity
Iniesta, R., Campbell, D., Venturini, C., Faconti, L., Singh, S., Irvin, M. R., Cooper-DeHoff, R. M., Johnson, J. A., Turner, S. T., Arnett, D. K., Weale, M. E., Warren, H., Munroe, P. B., Cruickshank, K., Padmanabhan, S., Lewis, C. & Chowienczyk, P., 1 Sept 2019, In: Hypertension (Dallas, Tex. : 1979). 74, 3, p. 614-622 9 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population
The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, 1 Aug 2019, In: American Journal of Transplantation. 19, 8, p. 2262-2273 12 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy
Guelfi, S., Botia, J. A., Thom, M., Ramasamy, A., Perona, M., Stanyer, L., Martinian, L., Trabzuni, D., Smith, C., Walker, R., Ryten, M., Reimers, M., Weale, M. E., Hardy, J. & Matarin, M., Jun 2019, In: Brain : a journal of neurology. 142, 6, p. 1616-1630 15 p.Research output: Contribution to journal › Article › peer-review
49 Citations (Scopus) -
Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study
United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3, Jun 2018, In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)132 Downloads (Pure) -
Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?
Verbelen, M., Weale, M. E. & Lewis, C. M., 13 Jun 2017, (E-pub ahead of print) In: The pharmacogenomics journal. 17, 5, p. 395-402Research output: Contribution to journal › Article › peer-review
Open AccessFile188 Citations (Scopus)351 Downloads (Pure)
Projects
- 11 Finished
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USING COMPUTATION, METABOLOMICS AND NEXT GENERATION SEQUENCING TO STUDY THE METABOLISM OF THE FAILING HEART
Edwards, L. (Primary Investigator), Clark, J. (Co-Investigator), Shattock, M. (Co-Investigator) & Weale, M. (Co-Investigator)
1/05/2014 → 30/04/2017
Project: Research
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Ancestry and biological Informative Markers for stratification of Hypertension: the AIM HY study
Chowienczyk, P. (Primary Investigator), Brown, M. (Co-Investigator), Chaturvedi, N. (Co-Investigator), Cruickshank, K. (Co-Investigator), Delaney, B. (Co-Investigator), Heagerty, A. (Co-Investigator), Hughes, A. (Co-Investigator), Lewis, C. (Co-Investigator), Mander, A. (Co-Investigator), Mant, J. (Co-Investigator), Martini, G. (Co-Investigator), McKevitt, C. (Co-Investigator), Parkin, D. (Co-Investigator), Prevost, T. (Co-Investigator), Spector, T. (Co-Investigator), Valdes, A. (Co-Investigator), Weale, M. (Co-Investigator), Wilkinson, I. (Co-Investigator) & Wolfe, C. (Co-Investigator)
14/04/2014 → 31/12/2023
Project: Research
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The Brazilian Bipolar Family Study : A 5 year follow-up study and molecular characterisation of phenotypes and mutations
Breen, G. (Primary Investigator), McGuffin, P. (Co-Investigator) & Weale, M. (Co-Investigator)
1/04/2014 → 31/03/2017
Project: Research
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The prevention and treatment of the complications of transplantation by stratification of risk
Lord, G. (Primary Investigator), Hernandez Fuentes, M. (Co-Investigator) & Weale, M. (Co-Investigator)
1/01/2014 → 31/12/2017
Project: Research
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Understanding the genetics of healthy skeletal muscle, the gatekeeper at the nexus between human health and disease
Edwards, L. (Primary Investigator), Harridge, S. (Primary Investigator) & Weale, M. (Co-Investigator)
1/01/2014 → 31/12/2016
Project: Research