Mike Weale

Mike Weale

Dr

 https://orcid.org/0000-0003-4593-1186
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  • 2019

    Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals: Genomic Precision Medicine May Dispense With Ethnicity

    Iniesta, R., Campbell, D., Venturini, C., Faconti, L., Singh, S., Irvin, M. R., Cooper-DeHoff, R. M., Johnson, J. A., Turner, S. T., Arnett, D. K., Weale, M. E., Warren, H., Munroe, P. B., Cruickshank, K., Padmanabhan, S., Lewis, C. & Chowienczyk, P., 1 Sept 2019, In: Hypertension (Dallas, Tex. : 1979). 74, 3, p. 614-622 9 p.

    Research output: Contribution to journal › Article › peer-review

    17 Citations (Scopus)

  • The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

    The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, 1 Aug 2019, In: American Journal of Transplantation. 19, 8, p. 2262-2273 12 p.

    Research output: Contribution to journal › Article › peer-review

    12 Citations (Scopus)

  • Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy

    Guelfi, S., Botia, J. A., Thom, M., Ramasamy, A., Perona, M., Stanyer, L., Martinian, L., Trabzuni, D., Smith, C., Walker, R., Ryten, M., Reimers, M., Weale, M. E., Hardy, J. & Matarin, M., Jun 2019, In: Brain : a journal of neurology. 142, 6, p. 1616-1630 15 p.

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    45 Citations (Scopus)
  • 2018

    Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study

    United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3, Jun 2018, In: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

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    44 Citations (Scopus)
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  • 2017

    Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?

    Verbelen, M., Weale, M. E. & Lewis, C. M., 13 Jun 2017, (E-pub ahead of print) In: The pharmacogenomics journal. 17, 5, p. 395-402

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    178 Citations (Scopus)
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  • Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

    Smith, B. N., Topp, S. D., Fallini, C., Shibata, H., Chen, H-J., Troakes, C., King, A., Ticozzi, N., Kenna, K. P., Soragia-Gkazi, A., Miller, J. W., Sato, A., Dias, D. M., Jeon, M., Vance, C., Wong, C. H., de Majo, M., Kattuah, W., Mitchell, J. C., Scotter, E. L., & 36 othersParkin, N. W., Sapp, P. C., Nolan, M., Nestor, P. J., Simpson, M., Weale, M., Lek, M., Baas, F., Vianney de Jong, J. M., Ten Asbroek, A. L. M. A., Redondo, A. G., Esteban-Pérez, J., Tiloca, C., Verde, F., Duga, S., Leigh, N., Pall, H., Morrison, K. E., Al-Chalabi, A., Shaw, P. J., Kirby, J., Turner, M. R., Talbot, K., Hardiman, O., Glass, J. D., De Belleroche, J., Maki, M., Moss, S. E., Miller, C., Gellera, C., Ratti, A., Al-Sarraj, S., Brown, R. H., Silani, V., Landers, J. E. & Shaw, C. E., 3 May 2017, In: Science Translational Medicine. 9, 388, 16 p., eaad9157.

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    115 Citations (Scopus)
    504 Downloads (Pure)

  • Novel genetic loci associated with hippocampal volume

    Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L., & 312 othersAxelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van der Grond, J., Van der Lee, S. J., Van der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C-Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., DeCarli, C., Delanty, N., Depondt, C., DeStefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B-C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J-J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J-L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van der Brug, M., van der Lugt, A., van der Wee, N. J. A., Van Haren, N. E. M., van 't Ent, D., Van Tol, M-J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., 18 Jan 2017, In: Nature Communications. 8, p. 13624 12 p.

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    211 Citations (Scopus)
    216 Downloads (Pure)

  • The Genetic Legacy of Zoroastrianism in Iran and India: Insights into Population Structure, Gene Flow, and Selection

    López, S., Thomas, M. G., van Dorp, L., Ansari-Pour, N., Stewart, S., Jones, A. L., Jelinek, E., Chikhi, L., Parfitt, T., Bradman, N., Weale, M. E. & Hellenthal, G., 7 Sept 2017, In: American Journal of Human Genetics. 101, 3, p. 353-368

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    10 Citations (Scopus)
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  • 2016

    Frontotemporal dementia: Insights into the biological underpinnings of disease through gene co-expression network analysis

    Ferrari, R., Forabosco, P., Vandrovcova, J., Botia Blaya, J., Guelfi, S., Warren, J. D., Momeni, P., Weale, M. E., Ryten, M. & Hardy, J., 24 Feb 2016, In: Molecular Neurodegeneration. 11, 1, 85.

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    33 Citations (Scopus)
    185 Downloads (Pure)

  • Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

    Psychosis Endophenotypes International Consortium, 23 Feb 2016, In: Nature Neuroscience. 19, 3, p. 420-431 12 p.

    Research output: Contribution to journal › Article › peer-review

    167 Citations (Scopus)

  • Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's

    Gagliano, S. A., Pouget, J. G., Hardy, J., Knight, J., Barnes, M. R., Ryten, M. & Weale, M. E., 27 Sept 2016, (Accepted/In press) In: Annals of Clinical and Translational Neurology.

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  • Novel genetic loci underlying human intracranial volume identified through genome-wide association

    Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van Der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., & 322 othersArmstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., Mckay, D. R., Mcwhirter, R., Milaneschi, Y., Mirza-schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van Der Grond, J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C., Cichon, S., Cookson, M. R., Corvin, A., Crespo-facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Delanty, N., Depondt, C., Destefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Longstreth, W. T., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J., Mattay, V. S., Mcdonald, C., Mcintosh, A. M., Mcmahon, K. L., Mcmahon, F. J., Mecocci, P., Melle, I., Meyer-lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Duijn, C. M., Van Haren, N. E. M., Van ′t Ent, D., Van Tol, M., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., Decarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., 31 Dec 2016, In: Nature Neuroscience. 19, 12, p. 1569-1582

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  • Systematic assessment of the influence of complement gene polymorphisms on kidney transplant outcome

    Ermini, L., Weale, M. E., Brown, K. M., Mesa, I. R., Howell, W. M., Vaughan, R., Chowdhury, P., Sacks, S. H. & Sheerin, N. S., Apr 2016, In: Immunobiology. 221, 4, p. 528–534

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    10 Citations (Scopus)
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  • 2015

    Common genetic variants influence human subcortical brain structures

    Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K., & 31 othersCuellar-Partida, G., den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Macare, C., Ramasamy, A., Walton, E., Johnson, R., Perez-Iglesias, R., Schofield, P. R., Williams, R. W., Davies, G. E., Fisher, S. E., Lovestone, S., McDonald, C., Simmons, A., Weale, M. E., Schumann, G. & The Alzheimer’s Disease Neuroimaging Initiative, 9 Apr 2015, In: NATURE. 520, 7546, p. 224-229 21 p.

    Research output: Contribution to journal › Article › peer-review

    611 Citations (Scopus)

  • Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD

    Yu, D., Mathews, C. A., Scharf, J. M., Neale, B. M., Davis, L. K., Gamazon, E. R., Derks, E. M., Evans, P., Edlund, C. K., Crane, J., Fagerness, J. A., Osiecki, L., Gallagher, P., Gerber, G., Haddad, S., Illmann, C., McGrath, L. M., Mayerfeld, C., Arepalli, S., Barlassina, C., & 135 othersBarr, C. L., Bellodi, L., Benarroch, F., Berrió, G. B., Bienvenu, O. J., Black, D. W., Bloch, M. H., Brentani, H., Bruun, R. D., Budman, C. L., Camarena, B., Campbell, D. D., Cappi, C., Silgado, J. C. C., Cavallini, M. C., Chavira, D. A., Chouinard, S., Cook, E. H., Cookson, M. R., Coric, V., Cullen, B., Cusi, D., Delorme, R., Denys, D., Dion, Y., Eapen, V., Egberts, K., Falkai, P., Fernandez, T., Fournier, E., Garrido, H., Geller, D., Gilbert, D. L., Girard, S. L., Grabe, H. J., Grados, M. A., Greenberg, B. D., Gross-Tsur, V., Grünblatt, E., Hardy, J., Heiman, G. A., Hemmings, S. M. J., Herrera, L. D., Hezel, D. M., Hoekstra, P. J., Jankovic, J., Kennedy, J. L., King, R. A., Konkashbaev, A. I., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J. F., Lennertz, L., Liu, C., Lochner, C., Lowe, T. L., Lupoli, S., Macciardi, F., Maier, W., Manunta, P., Marconi, M., McCracken, J. T., Mesa Restrepo, S. C., Moessner, R., Moorjani, P., Morgan, J., Muller, H., Murphy, D. L., Naarden, A. L., Nurmi, E., Ochoa, W. C., Ophoff, R. A., Pakstis, A. J., Pato, M. T., Pato, C. N., Piacentini, J., Pittenger, C., Pollak, Y., Rauch, S. L., Renner, T., Reus, V. I., Richter, M. A., Riddle, M. A., Robertson, M. M., Romero, R., Rosário, M. C., Rosenberg, D., Ruhrmann, S., Sabatti, C., Salvi, E., Sampaio, A. S., Samuels, J., Sandor, P., Service, S. K., Sheppard, B., Singer, H. S., Smit, J. H., Stein, D. J., Strengman, E., Tischfield, J. A., Turiel, M., Valencia Duarte, A. V., Vallada, H., Veenstra-VanderWeele, J., Walitza, S., Wang, Y., Weale, M., Weiss, R., Wendland, J. R., Westenberg, H. G. M., Shugart, Y. Y., Hounie, A. G., Miguel, E. C., Nicolini, H., Wagner, M., Ruiz-Linares, A., Cath, D. C., McMahon, W., Posthuma, D., Oostra, B. A., Nestadt, G., Rouleau, G. A., Purcell, S., Jenike, M. A., Heutink, P., Hanna, G. L., Conti, D. V., Arnold, P. D., Freimer, N. B., Stewart, S. E., Knowles, J. A., Cox, N. J. & Pauls, D. L., Jan 2015, In: The American Journal of Psychiatry. 172, 1, p. 82-93 12 p.

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    114 Citations (Scopus)

  • Network-informed gene ranking tackles genetic heterogeneity in exome-sequencing studies of monogenic disease

    Dand, N., Schulz, R., Weale, M. E., Southgate, L., Oakey, R. J., Simpson, M. A. & Schlitt, T., 1 Dec 2015, In: Human Mutation. 36, 12, p. 1135-1144 10 p.

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    6 Citations (Scopus)
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  • Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): A genetic association study in UK Biobank

    Wain, L. V., Shrine, N., Miller, S., Jackson, V. E., Ntalla, I., Artigas, M. S., Billington, C. K., Kheirallah, A. K., Allen, R., Cook, J. P., Probert, K., Obeidat, M., Bossé, Y., Hao, K., Postma, D. S., Paré, P. D., Ramasamy, A., Mägi, R., Mihailov, E., Reinmaa, E., & 138 othersMelén, E., O'Connell, J., Frangou, E., Delaneau, O., Freeman, C., Petkova, D., McCarthy, M., Sayers, I., Deloukas, P., Hubbard, R., Pavord, I., Hansell, A. L., Thomson, N. C., Zeggini, E., Morris, A. P., Marchini, J., Strachan, D. P., Tobin, M. D., Hall, I. P., Farrall, M., Barroso, I., Anderson, C. A., Botía, J., Vandrocova, J., Guelfi, S., D'Sa, K., Ryten, M., Trabzuni, D., Matarin, M., Hardy, J. A., Weale, M. E., Varghese, V., Forabosco, P., Farmer, A., McGuffin, P., Zgaga, L., Wilson, J. F., Wild, S. H., Campbell, H., Rudan, I., Smith, C., Walker, R., Liu, J. Z., Tozzi, F., Muglia, P., Waterworth, D. M., Pillai, S. G., Yuan, X., Mooser, V., Middleton, L., Kooner, J., Chambers, J. C., Berrettini, W., Knouff, C. W., Waeber, G., Vollenweider, P., Preisig, M., Wareham, N. J., Zhao, J. H., Loos, R. J. F., Khaw, K. T., Grundy, S., Barter, P., Mahley, R., Kesaniemi, A., McPherson, R., Vincent, J. B., Strauss, J., Kennedy, J. L., Day, R., Matthews, K., Bakke, P., Gulsvik, A., Lucae, S., Ising, M., Brueckl, T., Horstmann, S., Wichmann, H. E., Rawal, R., Wichmann, H. E., Lamina, C., Dahmen, N., Polasek, O., Kolcic, I., Huffman, J., Campbell, S., Vitart, V., Hayward, C., Wright, A. F., Burnett, M. S., Devaney, J. M., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Epstein, S., Reilly, M. P., Li, M., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Rader, D. J., Ellinghaus, D., Lieb, W., Franke, A., Uda, M., Busonero, F., Terracciano, A., Schlessinger, D., Xiao, X., Scheet, P., St Clair, D., Rujescu, D., Abecasis, G. R., Grabe, H. J., Teumer, A., Völzke, H., Petersmann, A., John, U., Wright, B. J., Thompson, J. R., Balmforth, A. J., Hall, A. S., Samani, N. J., Ahmad, T., Mathew, C. G., Parkes, M., Satsangi, J., Caulfield, M., Munroe, P. B., Dominiczak, A., Worthington, J., Thomson, W., Eyre, S., Barton, A. & Francks, C., Oct 2015, In: The Lancet Respiratory Medicine. 3, 10, p. 769-781 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    284 Citations (Scopus)

  • Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes

    Prescott, N. J., Lehne, B., Stone, K., Lee, J. C., Taylor, K., Knight, J., Papouli, E., Mirza, M. M., Simpson, M. A., Spain, S. L., Lu, G., Fraternali, F., Bumpstead, S. J., Gray, E., Amar, A., Bye, H., Green, P., Chung-Faye, G., Hayee, BH., Pollok, R., & 10 othersSatsangi, J., Parkes, M., Barrett, J. C., Mansfield, J. C., Sanderson, J., Lewis, C. M., Weale, M. E., Schlitt, T., Mathew, C. G. & UK IBD Genetics Consortium, 11 Feb 2015, In: PL o S Genetics. 11, 2, 19 p., e1004955.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Citations (Scopus)
  • 2014

    A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization

    Gagliano, S. A., Barnes, M. R., Weale, M. E. & Knight, J., 20 May 2014, In: PLOS One. 9, 5, 14 p., e98122.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Citations (Scopus)

  • A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis

    Fogh, I., Ratti, A., Gellera, C., Lin, K., Tiloca, C., Moskvina, V., Corrado, L., Sorarù, G., Cereda, C., Corti, S., Gentilini, D., Calini, D., Castellotti, B., Mazzini, L., Querin, G., Gagliardi, S., Del Bo, R., Conforti, F. L., Siciliano, G., Inghilleri, M., & 31 othersSaccà, F., Bongioanni, P., Penco, S., Corbo, M., Sorbi, S., Filosto, M., Ferlini, A., Di Blasio, A. M., Signorini, S., Shatunov, A., Jones, A., Shaw, P. J., Morrison, K. E., Farmer, A. E., Van Damme, P., Robberecht, W., Chiò, A., Traynor, B. J., Sendtner, M., Melki, J., Meininger, V., Hardiman, O., Andersen, P. M., Leigh, N. P., Glass, J. D., Shaw, C. E., Weale, M. E., Lewis, C. M., Al-Chalabi, A., Powell, J. & the SLAGEN Consortium Collaborators, 15 Apr 2014, In: Human Molecular Genetics. 23, 8, p. 2220-2231 12 p., N/A.

    Research output: Contribution to journal › Article › peer-review

    107 Citations (Scopus)

  • Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy

    Ferrari, R., Ryten, M., Simone, R., Trabzuni, D., Nicolaou, N., Hondhamuni, G., Ramasamy, A., Vandrovcova, J., Weale, M. E., Lees, A. J., Momeni, P., Hardy, J., de Silva, R. & UK Brain Expression Consortium, Jun 2014, In: Neurobiology of Aging. 35, 6, p. 1514.e1-1514.e12 12 p.

    Research output: Contribution to journal › Article › peer-review

    32 Citations (Scopus)

  • Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme CYP24A1 in multiple sclerosis

    Ramasamy, A., Trabzuni, D., Forabosco, P., Smith, C., Walker, R., Dillman, A., Sveinbjornsdottir, S., Hardy, J., Weale, M. E. & Ryten, M., Mar 2014, In: Multiple Sclerosis and Related Disorders. 3, 2, p. 211-219 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Citations (Scopus)

  • Genetic variability in the regulation of gene expression in ten regions of the human brain

    Ramasamy, A., Trabzuni, D., Guelfi, S., Varghese, V., Smith, C., Walker, R., De, T., Coin, L., de Silva, R., Cookson, M. R., Singleton, A. B., Hardy, J., Ryten, M., Weale, M. E. & UK Brain Expression Consortium, Oct 2014, In: Nature Neuroscience. 17, 10, p. 1418-1428 11 p.

    Research output: Contribution to journal › Article › peer-review

    492 Citations (Scopus)

  • Genome-Scale Methods Converge on Key Mitochondrial Genes for the Survival of Human Cardiomyocytes in Hypoxia

    Edwards, L. M., Sigurdsson, M. I., Robbins, P. A., Weale, M. E., Cavalleri, G. L., Montgomery, H. E. & Thiele, I., Aug 2014, In: Circulation-Cardiovascular Genetics. 7, 4, p. 407-415 16 p.

    Research output: Contribution to journal › Article › peer-review

    8 Citations (Scopus)

  • Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris

    Navarini, A. A., Simpson, M. A., Weale, M., Knight, J., Carlavan, I., Reiniche, P., Burden, D. A., Layton, A., Bataille, V., Allen, M., Pleass, R., Pink, A., Creamer, D., English, J., Munn, S., Walton, S., Willis, C., Deret, S., Voegel, J. J., Spector, T., & 4 othersSmith, C. H., Trembath, R. C., Barker, J. N. & Acne Genetic Study Grp, 13 Jun 2014, In: Nature Communications. 5, 1, 6 p., 4020.

    Research output: Contribution to journal › Article › peer-review

    61 Citations (Scopus)

  • Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

    Nalls, M. A., Pankratz, N., Lill, C. M., Do, C. B., Hernandez, D. G., Saad, M., DeStefano, A. L., Kara, E., Bras, J., Sharma, M., Schulte, C., Keller, M. F., Arepalli, S., Letson, C., Edsall, C., Stefansson, H., Liu, X., Pliner, H., Lee, J. H., Cheng, R., & 29 othersIkram, M. A., Ioannidis, J. P. A., Hadjigeorgiou, G. M., Bis, J. C., Martinez, M., Perlmutter, J. S., Goate, A., Marder, K., Fiske, B., Sutherland, M., Xiromerisiou, G., Myers, R. H., Clark, L. N., Stefansson, K., Hardy, J. A., Heutink, P., Chen, H., Wood, N. W., Houlden, H., Payami, H., Brice, A., Scott, W. K., Gasser, T., Bertram, L., Eriksson, N., Foroud, T., Singleton, A. B., International Parkinson's Disease Genomics Consortium (IPDGC) & Weale, M., Sept 2014, In: Nature Genetics. 46, 9, p. 989-93 5 p.

    Research output: Contribution to journal › Article › peer-review

    1440 Citations (Scopus)

  • Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

    Cruchaga, C., Karch, C. M., Jin, S. C., Benitez, B. A., Cai, Y., Guerreiro, R., Harari, O., Norton, J., Budde, J., Bertelsen, S., Jeng, A. T., Cooper, B., Skorupa, T., Carrell, D., Levitch, D., Hsu, S., Choi, J., Ryten, M., Hardy, J., Ryten, M., & 31 othersTrabzuni, D., Weale, M. E., Ramasamy, A., Smith, C., Sassi, C., Bras, J., Gibbs, J. R., Hernandez, D. G., Lupton, M. K., Powell, J., Forabosco, P., Ridge, P. G., Corcoran, C. D., Tschanz, J. T., Norton, M. C., Munger, R. G., Schmutz, C., Leary, M., Demirci, F. Y., Bamne, M. N., Wang, X., Lopez, O. L., Ganguli, M., Medway, C., Turton, J., Lord, J., Braae, A., Barber, I., Brown, K., Passmore, P. & UK Brain Expression Consortium, 23 Jan 2014, In: Nature. 505, 7484, p. 550-554 5 p.

    Research output: Contribution to journal › Article › peer-review

    375 Citations (Scopus)

  • The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

    Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C., Andreassen, O. A., & 31 othersApostolova, L. G., Appel, K., Armstrong, N. J., Aribisala, B., Bastin, M. E., Bauer, M., Bearden, C. E., Bergmann, O., Binder, E. B., Blangero, J., Bockholt, H. J., Bøen, E., Bois, C., Boomsma, D. I., Conrod, P., Delvecchio, G., Dima, D., Dimitrova, R., Frangou, S., Loth, E., Lourdusamy, A., McDonald, C., Phillips, M., Ramasamy, A., Scanlon, C., Simmons, A., Walker, R., Weale, M. E., Schofield, P. R., Lawrence, N. S. & the Alzheimer’s Disease Neuroimaging Initiative, EPIGEN Consortium, IMAGEN Consortium, Saguenay Youth Study (SYS) Group, 8 Jan 2014, (E-pub ahead of print) In: Brain Imaging and Behavior. N/A, N/A, p. N/A 30 p., N/A.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    570 Citations (Scopus)
  • 2013

    Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A

    Kasperaviciute, D., Catarino, C. B., Matarin, M., Leu, C., Novy, J., Tostevin, A., Leal, B., Hessel, E. V. S., Hallmann, K., Hildebrand, M. S., Dahl, H-H. M., Ryten, M., Trabzuni, D., Ramasamy, A., Alhusaini, S., Doherty, C. P., Dorn, T., Hansen, J., Krämer, G., Steinhoff, B. J., & 31 othersZumsteg, D., Duncan, S., Kälviäinen, R. K., Eriksson, K. J., Kantanen, A-M., Pandolfo, M., Gruber-Sedlmayr, U., Schlachter, K., Reinthaler, E. M., Stogmann, E., Zimprich, F., Théâtre, E., Smith, C., O'Brien, T. J., Meng Tan, K., Petrovski, S., Robbiano, A., Paravidino, R., Zara, F., Striano, P., Sperling, M. R., Buono, R. J., Hakonarson, H., Chaves, J., Costa, P. P., Silva, B. M., da Silva, A. M., de Graan, P. N. E., Koeleman, B. P. C., Weale, M. E. & UK Brain Expression Consortium, Oct 2013, In: Brain. 136, 10, p. 3140-3150 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    135 Citations (Scopus)

  • Fine-Mapping, Gene Expression and Splicing Analysis of the Disease Associated LRRK2 Locus

    Trabzuni, D., Ryten, M., Emmett, W., Ramasamy, A., Lackner, K. J., Zeller, T., Walker, R., Smith, C., Lewis, P. A., Mamais, A., de Silva, R., Vandrovcova, J., Hernandez, D., Nalls, M. A., Sharma, M., Garnier, S., Lesage, S., Simon-Sanchez, J., Gasser, T., Heutink, P., & 10 othersBrice, A., Singleton, A., Cai, H., Schadt, E., Wood, N. W., Bandopadhyay, R., Weale, M. E., Hardy, J., Plagnol, V. & International Parkinson Disease Genomics Consortium (IPDGC), 13 Aug 2013, In: PL o S One . 8, 8, 9 p., e70724.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    41 Citations (Scopus)

  • Gene expression changes with age in skin, adipose tissue, blood and brain

    Glass, D., Vinuela, A., Davies, M. N., Ramasamy, A., Parts, L., Knowles, D., Brown, A. A., Hedman, A. K., Small, K. S., Buil, A., Grundberg, E., Nica, A. C., Di Meglio, P., Nestle, F. O., Ryten, M., Durbin, R., McCarthy, M. I., Deloukas, P., Dermitzakis, E. T., Weale, M. E., & 4 othersBataille, V., Spector, T. D., UK Brain Expression Consortium & MuTHER Consortium, 26 Jul 2013, In: GENOME BIOLOGY. 14, 7, p. N/A 12 p., R75.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    216 Citations (Scopus)

  • Genetic Signatures Reveal High-Altitude Adaptation in a Set of Ethiopian Populations

    Huerta-Sanchez, E., DeGiorgio, M., Pagani, L., Tarekegn, A., Ekong, R., Antao, T., Cardona, A., Montgomery, H. E., Cavalleri, G. L., Robbins, P. A., Weale, M. E., Bradman, N., Bekele, E., Kivisild, T., Tyler-Smith, C. & Nielsen, R., Aug 2013, In: Molecular Biology and Evolution. 30, 8, p. 1877-1888 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    155 Citations (Scopus)

  • Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci

    Holton, P., Ryten, M., Nalls, M., Trabzuni, D., Weale, M. E., Hernandez, D., Crehan, H., Gibbs, J. R., Mayeux, R., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Schellenberg, G. D., Ramirez-Restrepo, M., Engel, A., Myers, A. J., Corneveaux, J. J., Huentelman, M. J., Dillman, A., Cookson, M. R., & 5 othersReiman, E. M., Singleton, A., Hardy, J., Guerreiro, R. & Alzheimer's Dis Genetics Consortiu, Mar 2013, In: Annals of Human Genetics. 77, 2, p. 85-105 21 p.

    Research output: Contribution to journal › Article › peer-review

    40 Citations (Scopus)

  • Insights into TREM2 biology by network analysis of human brain gene expression data

    Forabosco, P., Ramasamy, A., Trabzuni, D., Walker, R., Smith, C., Bras, J., Levine, A. P., Hardy, J., Pocock, J. M., Guerreiro, R., Weale, M. E. & Ryten, M., Dec 2013, In: Neurobiology of Aging. 34, 12, p. 2699-2714 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    139 Citations (Scopus)

  • Resolving the polymorphism-in-probe problem is critical for correct interpretation of expression QTL studies

    Ramasamy, A., Trabzuni, D., Gibbs, J. R., Dillman, A., Hernandez, D. G., Arepalli, S., Walker, R., Smith, C., Ilori, G. P., Shabalin, A. A., Li, Y., Singleton, A. B., Cookson, M. R., Hardy, J., Ryten, M., Weale, M. E., NABEC & UKBEC, Apr 2013, In: Nucleic Acids Research. 41, 7, 12 p., e88.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Citations (Scopus)

  • The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder

    Smith, B. N., Newhouse, S., Shatunov, A., Vance, C., Topp, S., Johnson, L., Miller, J., Lee, Y., Troakes, C., Scott, K. M., Jones, A., Gray, I., Wright, J., Hortobágyi, T., Al-Sarraj, S., Rogelj, B., Powell, J., Lupton, M., Lovestone, S., Sapp, P. C., & 26 othersWeber, M., Nestor, P. J., Schelhaas, H. J., Asbroek, A. A. T., Silani, V., Gellera, C., Taroni, F., Ticozzi, N., Van den Berg, L., Veldink, J., Van Damme, P., Robberecht, W., Shaw, P. J., Kirby, J., Pall, H., Morrison, K. E., Morris, A., de Belleroche, J., Vianney de Jong, J. M. B., Baas, F., Andersen, P. M., Landers, J., Brown, R. H., Weale, M. E., Al-Chalabi, A. & Shaw, C. E., Jan 2013, In: European Journal of Human Genetics. 21, 1, p. 102-108 7 p., N/A.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    190 Citations (Scopus)

  • Widespread sex differences in gene expression and splicing in the adult human brain

    Trabzuni, D., Ramasamy, A., Imran, S., Walker, R., Smith, C., Weale, M. E., Hardy, J., Ryten, M. & North American Brain Expression Consortium, 22 Nov 2013, In: Nature Communications. 4, 7 p., 2771.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    212 Citations (Scopus)
  • 2012

    Analysis of European case-control studies suggests that common inherited variation in mitochondrial DNA is not involved in susceptibility to amyotrophic lateral sclerosis

    Ingram, C. J. E., Weale, M. E., Plaster, C. A., Morrison, K. E., Goodall, E. F., Pall, H. S., Beck, M., Jablonka, S., Sendtner, M., Fisher, E. M. C., Bradman, N. & Kasperaviciute, D., Jun 2012, In: Amyotrophic Lateral Sclerosis (United Kingdom). 13, 4, p. 341-346 6 p.

    Research output: Contribution to journal › Article › peer-review

    13 Citations (Scopus)

  • Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS

    Ermini, L., Goodship, T. H. J., Strain, L., Weale, M. E., Sacks, S. H., Cordell, H. J., Fremeaux-Bacchi, V. & Sheerin, N. S., Jan 2012, In: Molecular Immunology. 49, 4, p. 640 - 648 9 p.

    Research output: Contribution to journal › Article › peer-review

    35 Citations (Scopus)

  • Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

    Knight, J., Spain, S. L., Capon, F., Hayday, A., Nestle, F. O., Clop, A., Wellcome Trust Case Control Consortium, Barker, J. N., Weale, M. E. & Trembath, R. C., Dec 2012, In: Human Molecular Genetics. 21, 23, p. 5185-92 8 p.

    Research output: Contribution to journal › Article › peer-review

    51 Citations (Scopus)

  • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, A. D., Smith, C. H., Cork, M. J., & 31 othersEstivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Onoufriadis, A., Weale, M. E., Campbell, L. E., Mathew, C. G., Plomin, R., Viswanathan, A. C., Gray, E., Weston, P., Barker, J. N. W. N., Trembath, R. C. & Collaborative Association Study of Psoriasis (CASP), Dec 2012, In: Nature Genetics. 44, 12, p. 1341-1348 8 p.

    Research output: Contribution to journal › Article › peer-review

    799 Citations (Scopus)

  • Identification of common variants associated with human hippocampal and intracranial volumes

    Stein, J. L., Medland, S. E., Vasquez, A. A., Hibar, D. P., Senstad, R. E., Winkler, A. M., Toro, R., Appel, K., Bartecek, R., Bergmann, Ø., Bernard, M., Brown, A. A., Cannon, D. M., Chakravarty, M. M., Christoforou, A., Domin, M., Grimm, O., Hollinshead, M., Holmes, A. J., Homuth, G., & 30 othersHottenga, J-J., Langan, C., Lopez, L. M., Hansell, N. K., Hwang, K. S., Kim, S., Laje, G., Lee, P. H., Liu, X., Loth, E., Lourdusamy, A., Mattingsdal, M., Mohnke, S., Maniega, S. M., Nho, K., Nugent, A. C., O'Brien, C., Papmeyer, M., Pütz, B., Ramasamy, A., Rasmussen, J., Rijpkema, M., Risacher, S. L., Roddey, J. C., Rose, E. J., Ryten, M., Shen, L., Schumann, G., Weale, M. E. & Alzheimer's Disease Neuroimaging Initiative, May 2012, In: Nature Genetics. 44, 5, p. 552-561 10 p.

    Research output: Contribution to journal › Article › peer-review

    516 Citations (Scopus)

  • Inferring separate parental admixture components in unknown DNA samples using autosomal SNPs

    Crouch, D. J. M. & Weale, M. E., Dec 2012, In: European Journal of Human Genetics. 20, 12, p. 1283-1289 7 p.

    Research output: Contribution to journal › Article › peer-review

    4 Citations (Scopus)

  • Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain

    Hernandez, D. G., Nalls, M. A., Moore, M., Chong, S., Dillman, A., Trabzuni, D., Gibbs, J. R., Ryten, M., Arepalli, S., Weale, M. E., Zonderman, A. B., Troncoso, J., O'Brien, R., Walker, R., Smith, C., Bandinelli, S., Traynor, B. J., Hardy, J., Singleton, A. B. & Cookson, M. R., Jul 2012, In: Neurobiology of Disease. 47, 1, p. 20-28 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    100 Citations (Scopus)

  • Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

    Patani, R., Lewis, P. A., Trabzuni, D., Puddifoot, C. A., Wyllie, D. J. A., Walker, R., Smith, C., Hardingham, G. E., Weale, M., Hardy, J., Chandran, S. & Ryten, M., Aug 2012, In: Journal of Neurochemistry. 122, 4, p. 738-751 14 p.

    Research output: Contribution to journal › Article › peer-review

    43 Citations (Scopus)

  • MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

    Trabzuni, D., Wray, S., Vandrovcova, J., Ramasamy, A., Walker, R., Smith, C., Luk, C., Gibbs, J. R., Dillman, A., Hernandez, D. G., Arepalli, S., Singleton, A. B., Cookson, M. R., Pittman, A. M., de Silva, R., Weale, M. E., Hardy, J. & Ryten, M., 15 Sept 2012, In: Human Molecular Genetics. 21, 18, p. 4094-4103 10 p., dds238.

    Research output: Contribution to journal › Article › peer-review

    170 Citations (Scopus)

  • Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies (Addendum)

    Trabzuni, D., Ryten, M., Walker, R., Smith, C., Imran, S., Ramasamy, A., Weale, M. & Hardy, J., 8 Dec 2012, In: Journal of Neurochemistry. 120, 3, p. 473 - 473 1 p.

    Research output: Contribution to journal › Article › peer-review

  • 2011

    A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease

    Plagnol, V., Nalls, M. A., Bras, J. M., Hernandez, D. G., Sharma, M., Sheerin, U-M., Saad, M., Simon-Sanchez, J., Schulte, C., Lesage, S., Sveinbjornsdottir, S., Amouyel, P., Arepalli, S., Band, G., Barker, R. A., Bellinguez, C., Ben-Shlomo, Y., Berendse, H. W., Berg, D., Bhatia, K., & 119 othersde Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J-F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Durif, F., Duerr, A., Edkins, S., Evans, J. R., Foltynie, T., Freeman, C., Gao, J., Gardner, M., Gibbs, J. R., Goate, A., Gray, E., Guerreiro, R., Gustafsson, O., Harris, C., Hellenthal, G., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jonsson, P. V., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., McNeill, A., Moorby, C., Moore, M., Morris, H., Morrison, K. E., Mudanohwo, E., O'Sullivan, S. S., Pearson, J., Pearson, R., Perlmutter, J. S., Petursson, H., Pirinen, M., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Sidransky, E., de Silva, R., Smith, C., Spencer, C. C. A., Stefansson, H., Steinberg, S., Stockton, J. D., Strange, A., Su, Z., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Vandrovcova, J., Velseboer, D., Vidailhet, M., Vukcevic, D., Walker, R., van de Warrenburg, B., Weale, M. E., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefansson, K., Martinez, M., Donnelly, P., Singleton, A. B., Hardy, J., Heutink, P., Brice, A., Gasser, T. & Wood, N. W., 2011, In: PL o S Genetics. 7, 6, e1002142.

    Research output: Contribution to journal › Article › peer-review

    250 Citations (Scopus)

  • Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

    Trabzuni, D., Ryten, M., Walker, R., Smith, C., Imran, S., Ramasamy, A., Weale, M. E. & Hardy, J., Oct 2011, In: Journal of Neurochemistry. 119, 2, p. 275-282 8 p., N/A.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    177 Citations (Scopus)

  • Using Functional Annotation for the Empirical Determination of Bayes Factors for Genome-Wide Association Study Analysis

    Knight, J., Barnes, M. R., Breen, G. & Weale, M. E., 2011, In: PL o S One . 6, 4, e14808.

    Research output: Contribution to journal › Article › peer-review

    27 Citations (Scopus)
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