Research output per year
Research output per year
Personal profile
Research interests
We are interested in the basic processes that lead to myocardial necrosis and subsequent remodelling of the heart. Clincally these relate to myocardial infarction and heart failure. Our main focus is on the intracellular signals that drive these processes, in particular the role of protein kinases. Clincal research projects are mainly descriptive and are designed to increase understanding of how the heart adapts to exercise, myocardial ischaemia and other stresses.
Research interests (short)
Myocardial infarction; cardiac protection; signal transduction
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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ChaMP-CMD: A Phenotype-Blinded, Randomized Controlled, Cross-Over Trial
Sinha, A., Rahman, H., Douiri, A., Demir, O. M., De Silva, K., Clapp, B., Webb, I., Gulati, A., Pinho, P., Dutta, U., Ellis, H., Shah, A. M., Chiribiri, A., Marber, M., Webb, A. J. & Perera, D., 2 Jan 2024, In: Circulation. 149, 1, p. 36-47 12 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Rethinking False Positive Exercise Electrocardiographic Stress Tests by Assessing Coronary Microvascular Function
Sinha, A., Dutta, U., Demir, O. M., De Silva, K., Ellis, H., Belford, S., Ogden, M., Li Kam Wa, M., Morgan, H. P., Shah, A. M., Chiribiri, A., Webb, A. J., Marber, M., Rahman, H. & Perera, D., 16 Jan 2024, In: Journal of the American College of Cardiology. 83, 2, p. 291–299 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)206 Downloads (Pure) -
Characterizing Mechanisms of Ischemia in Patients With Myocardial Bridges
Sinha, A., Rahman, H., Rajani, R., Demir, O. M., Li Kam Wa, M. E., Morgan, H., Ezad, S. M., Ellis, H., Hogan, D., Gulati, A., Shah, A. M., Chiribiri, A., Webb, A., Marber, M. & Perera, D., 6 Nov 2023, (E-pub ahead of print) In: Circulation. Cardiovascular interventions. 17, 1, p. E013657Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Direct Comparison of the Circadian Rhythm of Cardiac Myosin-Binding Protein C (cMyC) and Cardiac Troponin
Alaour, B., Kaier, T. E., Hasselbalch, R. B., van Doorn, W., Meex, S. & Marber, M., 1 Jul 2023, In: The journal of applied laboratory medicine. 8, 4, p. 831-834 4 p.Research output: Contribution to journal › Letter › peer-review
1 Citation (Scopus) -
Viability and Outcomes with Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction: Prespecified analysis of the REVIVED-BCIS2 randomized clinical trial
Perera, D., Ryan, M., Morgan, H., Greenwood, J. P., Petrie, M. C., Dodd, M., Weerackody, R., Masci, P.-G., Nazir, M., Papachristids, A., Chahal, N. S., Khattar, R. S., Ezad, S., Kapetanakis, S., Dixon, L. J., De Silva, K., McDiarmid, A. K., Marber, M., McDonagh, T. A. & McCann, G. P. & 3 others, , 21 Aug 2023, (Accepted/In press) In: JAMA Cardiology.Research output: Contribution to journal › Article › peer-review
File24 Downloads (Pure)
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Support for final product development and regulatory submission of an ultrasensitive point of care troponin test
Marber, M. (Primary Investigator) & Marber, M. (Primary Investigator)
NIHR National Institute For Health & Care Research
1/05/2024 → 31/07/2026
Project: Research
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Cardiac myosin-binding protein C (cMyC) fragmentation patterns in different types of myocardial infarction
Marber, M. (Primary Investigator), Marber, M. (Primary Investigator) & Mayr, M. (Co-Investigator)
5/10/2022 → 11/11/2025
Project: Research
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Investigation into the Mechanisms of Leaflet Thrombosis Following Trans-catheter Aortic Valve Implantation
Redwood, S. (Primary Investigator), Lee, J. (Co-Investigator), Marber, M. (Co-Investigator) & Marber, M. (Co-Investigator)
BMA British Medical Association
1/10/2020 → 31/10/2024
Project: Research
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Using protein-protein inhibitors to target p38α during myocardial ischemia
De Nicola, G. (Primary Investigator) & Marber, M. (Co-Investigator)
19/05/2019 → 18/03/2020
Project: Research
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BHF Research Excellence Award
Shah, A. (Primary Investigator), Botnar, R. (Co-Investigator), Chowienczyk, P. (Co-Investigator), Eaton, P. (Co-Investigator), Garcia-Manyes, S. (Co-Investigator), Gautel, M. (Co-Investigator), Giacca, M. (Co-Investigator), Irving, M. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), Otsu, K. (Co-Investigator), Ourselin, S. (Co-Investigator), Parsons, M. (Co-Investigator), Razavi, R. (Co-Investigator), Schnabel, J. (Co-Investigator), Shanahan, C. (Co-Investigator), Xu, Q. (Co-Investigator) & Phinikaridou, A. (Co-Investigator)
1/04/2019 → 31/03/2024
Project: Research
Activities
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Health Technology Appraisals by the National Institute for Clinical Excellence
Marber, M. (Member)
2001 → …Activity: Other › Types of Business and Community - Work on advisory panel to industry or government or non-government organisation
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the British Cardiac Society
Marber, M. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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the Cardiovascular Panel (Panel 1) for the UK Research Assessment Exercise 2008
Marber, M. (Member)
2001 → 2008Activity: Other › Types of External academic engagement - Membership of external research organisation
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Emerging Diagnostics Theme of the Guy's and St Thomas' Charity
Marber, M. (Chair)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation
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the Strategy Committee of the Guy's and St Thomas' Charity
Marber, M. (Member)
2001 → …Activity: Other › Types of External academic engagement - Membership of external research organisation