Search results

• Active

  Cardiac myosin-binding protein C (cMyC) fragmentation patterns in different types of myocardial infarction

  Marber, M. (Primary Investigator), Marber, M. (Primary Investigator) & Mayr, M. (Co-Investigator)

  BHF British Heart Foundation

  5/10/2022 → 4/10/2025

  Project: Research

• Finished

  Investigation into the Mechanisms of Leaflet Thrombosis Following Trans-catheter Aortic Valve Implantation

  Redwood, S. (Primary Investigator), Lee, J. (Co-Investigator), Marber, M. (Co-Investigator) & Marber, M. (Co-Investigator)

  BMA British Medical Association

  1/10/2020 → 31/10/2024

  Project: Research

• Using protein-protein inhibitors to target p38α during myocardial ischemia

  De Nicola, G. (Primary Investigator) & Marber, M. (Co-Investigator)

  MRC Medical Research Council

  19/05/2019 → 18/03/2020

  Project: Research

  • Protein Inhibitor 100%
  • Heart Muscle Ischemia 100%
  • Protein 100%

• BHF Research Excellence Award

  Shah, A. (Primary Investigator), Botnar, R. (Co-Investigator), Chowienczyk, P. (Co-Investigator), Eaton, P. (Co-Investigator), Garcia-Manyes, S. (Co-Investigator), Gautel, M. (Co-Investigator), Giacca, M. (Co-Investigator), Irving, M. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), Otsu, K. (Co-Investigator), Ourselin, S. (Co-Investigator), Parsons, M. (Co-Investigator), Razavi, R. (Co-Investigator), Schnabel, J. (Co-Investigator), Shanahan, C. (Co-Investigator), Xu, Q. (Co-Investigator) & Phinikaridou, A. (Co-Investigator)

  BHF British Heart Foundation

  1/04/2019 → 31/03/2024

  Project: Research

• The biological variability of cardiac myosin-binding protein C (cMyC) and its ability to assist in the early triage of patients with suspected acute myocardial infarction

  Marber, M. (Primary Investigator)

  BHF British Heart Foundation

  1/02/2019 → 31/01/2021

  Project: Research

• Microvascular Inflammation in heart failure with preserved ejection fraction (HFpEF)

  Redwood, S. (Primary Investigator), Marber, M. (Co-Investigator) & Allen, C. (Co-Investigator)

  BHF British Heart Foundation

  1/01/2019 → 31/12/2021

  Project: Research

• Non-invasive Differentiation of Microvascular Disease from CAD by Perfusion CMR: Validation Against Invasive Indices of Microvascular Function.

  Chiribiri, A. (Primary Investigator), Ismail, T. (Co-Investigator), Marber, M. (Co-Investigator) & Redwood, S. (Co-Investigator)

  1/09/2017 → 31/08/2020

  Project: Research

• Cardiac Myosin-Binding Protein C (cMyC) in myocardial infarction

  Marber, M. (Primary Investigator)

  1/08/2017 → 31/07/2020

  Project: Research

• NIHR Biomedical Research Centre. Funding for Financial Years 2017/18, 2018/19

  Wolfe, C. (Primary Investigator), Parsons, M. (Primary Investigator), Gould, H. (Primary Investigator), Corrigan, C. (Primary Investigator), Greenough, A. (Primary Investigator), Peakman, M. (Primary Investigator), Vyse, T. (Primary Investigator), Antoniou, M. (Primary Investigator), Oakey, R. (Primary Investigator), McGrath, J. (Primary Investigator), Karagiannis, S. (Primary Investigator), Barker, J. (Primary Investigator), Flohr, C. (Primary Investigator), Tziotzios, C. (Primary Investigator), Whittaker, S. (Primary Investigator), Spector, T. (Primary Investigator), Watt, F. (Primary Investigator), Hayday, A. (Primary Investigator), Spencer, J. (Primary Investigator), Cope, A. (Primary Investigator), Malim, M. (Primary Investigator), Martin Serrano, J. (Primary Investigator), Edgeworth, J. (Primary Investigator), Cason, J. (Primary Investigator), Lord, G. (Primary Investigator), Dorling, A. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Lombardi, G. (Primary Investigator), Ostermann, M. (Primary Investigator), Shah, A. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Wells, C. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Sawyer, E. (Primary Investigator), Maher, J. (Primary Investigator), Tribe, R. (Primary Investigator), Ilic, D. (Primary Investigator), Poston, L. (Primary Investigator), Rutherford, M. (Primary Investigator), Gee, T. (Primary Investigator), Blower, P. (Primary Investigator), Edwards, D. (Primary Investigator), Sharpe, P. (Primary Investigator), Streit, A. (Primary Investigator), Naglik, J. (Primary Investigator), Tavassoli, M. (Primary Investigator) & McNaughton, P. (Primary Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2017 → 31/03/2022

  Project: Research

  • Biomedical Research 100%

• Developing inhibitors of the p38a-TAB1 protein interaction

  De Nicola, G. (Primary Investigator) & Marber, M. (Co-Investigator)

  1/01/2017 → 30/06/2018

  Project: Research

• King’s NMR Facility for structural biology, metabolic profiling and drug discovery

  Conte, M. (Primary Investigator), Avkiran, M. (Co-Investigator), Blower, P. (Co-Investigator), Dodding, M. (Co-Investigator), Eaton, P. (Co-Investigator), Gautel, M. (Co-Investigator), Irving, M. (Co-Investigator), Malim, M. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Otsu, K. (Co-Investigator), Pastore, A. (Co-Investigator), Pfuhl, M. (Co-Investigator), Poston, L. (Co-Investigator), Shah, A. (Co-Investigator), Shanahan, C. (Co-Investigator), Shattock, M. (Co-Investigator) & Williamson, C. (Co-Investigator)

  BHF British Heart Foundation, Wellcome Trust

  1/01/2017 → 31/12/2021

  Project: Research

• Non-invasive Differentiation of Microvascular Disease from CAD by Perfusion CMR: Validation Against Invasive Indices of Microvascular Function.

  Chiribiri, A. (Primary Investigator), Marber, M. (Co-Investigator) & Redwood, S. (Co-Investigator)

  1/09/2016 → 31/08/2019

  Project: Research

• Mechanisms of action of intervention in the PHOENIX trial: in women with preterm pre-eclampsia does planned delivery improve postpartum maternal cardiac function through attenuation of myocardial ischaemia at time of disease (PHOEBE study)?

  McCarthy, F. (Primary Investigator), Chappell, L. (Primary Investigator), Marber, M. (Co-Investigator), Poston, L. (Co-Investigator) & Seed, P. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/01/2016 → 30/09/2019

  Project: Research

• Investigating the haemodynamic and physiological principles underlying exercise induced angina, and glyceryl trinitrates anti-anginal effect, using invasive coronary and ventricular measures of coronary flow and cardiac work

  Redwood, S. (Primary Investigator), Joseph, J. (Co-Investigator) & Marber, M. (Co-Investigator)

  BHF British Heart Foundation

  1/10/2015 → 5/10/2018

  Project: Research

• Physiological role of RSK-mediated cardiac myosin-binding protein C phosphorylation

  Avkiran, M. (Primary Investigator), Gautel, M. (Co-Investigator) & Marber, M. (Co-Investigator)

  1/10/2015 → 30/09/2018

  Project: Research

• Characterising novel, and discovering new, biomarkers of early myocardial injury

  Marber, M. (Primary Investigator), Kaier, T. (Co-Investigator), Mayr, M. (Co-Investigator) & Perera, D. (Co-Investigator)

  BHF British Heart Foundation

  1/10/2015 → 30/09/2018

  Project: Research

• Comparison between Propofol and Inhaled Anaesthesia on cardiovascular morbidity and mortality following cardiac survery (COPIA) - a Multicentre Randomised Controlled Trial

  academic, A. (Primary Investigator) & Marber, M. (Co-Investigator)

  1/09/2015 → 31/08/2020

  Project: Research

• C-terminal phosphorylation of the sarcomeric Z-disk protein telethonin in the heart: Functional role and molecular mechanisms

  Avkiran, M. (Primary Investigator), Gautel, M. (Co-Investigator) & Marber, M. (Co-Investigator)

  1/07/2015 → 30/06/2019

  Project: Research

• Non-invasive differentiation of myocardial microvascular disease from epicardial coronary artery disease by perfusion CMR: validation against invasive indices of microvascular function.

  Chiribiri, A. (Primary Investigator), Marber, M. (Co-Investigator) & Redwood, S. (Co-Investigator)

  1/07/2015 → 30/06/2018

  Project: Research

• Comparing the Diagnostic and Prognostic Performance of Myosin Binding Protein C to Troponin I and Troponin T in Patients Presenting with Chest Pain

  Marber, M. (Primary Investigator)

  BHF British Heart Foundation

  1/06/2015 → 30/04/2016

  Project: Research

• An ischaemic cardiogenic shock swine model and randomised clinical study on the effects of cardiac assist strategies on coronary haemodynamics and myocardial oxygen consumption.

  Perera, D. (Primary Investigator) & Marber, M. (Co-Investigator)

  1/06/2015 → 1/12/2017

  Project: Research

• The haemodynamic effects of cardiac assist strategies.

  Perera, D. (Primary Investigator) & Marber, M. (Co-Investigator)

  1/06/2015 → 30/11/2017

  Project: Research

• Understanding the interaction between p38alpha mitogen-activated protein kinase and TAB1

  Marber, M. (Primary Investigator) & Conte, M. (Co-Investigator)

  BHF British Heart Foundation

  18/05/2015 → 17/05/2019

  Project: Research

• A cardiogenic shock swine model and clinical randomised study on the effects of cardiac assist strategies on myocardial oxygen supply and demand.

  Perera, D. (Primary Investigator) & Marber, M. (Co-Investigator)

  3/05/2015 → 2/11/2017

  Project: Research

• Comparison between Propofol and Inhaled Anaesthesia on cardiovascular morbidity and mortality following cardiac surgery (COPIA) - a Multicentre Randomised Controlled Trial

  academic, A. (Primary Investigator), Clark, J. (Co-Investigator), Marber, M. (Co-Investigator) & Mayr, M. (Co-Investigator)

  1/05/2015 → 30/04/2016

  Project: Research

• A proof of concept study for improved clinical management of patients with acute myocarditis based on a novel imaging algorithm T1 mapping

  Nagel, E. (Primary Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator) & Puntmann, V. (Co-Investigator)

  1/01/2015 → 31/12/2018

  Project: Research

• Strategies for optimal iron repletion in chronic heart failure

  Okonko, D. (Primary Investigator), Marber, M. (Co-Investigator) & Shah, A. (Co-Investigator)

  1/09/2014 → 1/09/2017

  Project: Research

• Comparison of propofol with isoflurane anaesthesia and clinical outcome after cardiac surgery (COPIA): a multicentre randomised controlled trial

  Ballard, C. (Primary Investigator) & Marber, M. (Co-Investigator)

  1/09/2014 → 31/08/2018

  Project: Research

• A randomised haemodynamic study on IABP and Impella in a swine model and in patients undergoing high risk PCI

  Marber, M. (Primary Investigator)

  1/05/2014 → 1/05/2017

  Project: Research

• Comparison of the pathophysiological aetiology of exercise vs mental stress-induced myocardial ischaemia

  Redwood, S. (Primary Investigator) & Marber, M. (Co-Investigator)

  BHF British Heart Foundation

  2/10/2013 → 31/12/2016

  Project: Research

• REVIVED - REVascularisation of Ischaemic Ventricular Dysfunction

  Perera, D. (Primary Investigator), Marber, M. (Co-Investigator) & Redwood, S. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/06/2013 → 31/12/2022

  Project: Research

• The assessment of cMyBP-C as a new diagnostic biomarker of myocardial infarction

  Marber, M. (Primary Investigator) & Redwood, S. (Co-Investigator)

  1/04/2013 → 31/03/2016

  Project: Research

• Elucidating the development of uremic cardiomyopathy in chronic kidney disease patients - are circulating cardiotonic steroids the missing link?

  Pavlovic, D. (Primary Investigator) & Marber, M. (Co-Investigator)

  10/01/2013 → 9/01/2018

  Project: Research

• Developing inhibitors of the p38α:TAB1 interaction

  Marber, M. (Primary Investigator)

  KHP King's Health Partners

  7/01/2013 → 31/10/2014

  Project: Research

• Investigating the haemodynamic and physiological principles underlying cold induced angina using invasive coronary measures of flow and cardiac workload

  Marber, M. (Primary Investigator) & Redwood, S. (Primary Investigator)

  BHF British Heart Foundation

  1/01/2013 → 1/10/2017

  Project: Research

• The assessment of coronary blood flow and myocardial work in patients with warm-up angina; increased flow or reduced need?

  Marber, M. (Primary Investigator), Redwood, S. (Primary Investigator), Chowienczyk, P. (Co-Investigator), Perera, D. (Co-Investigator) & academic, A. (Co-Investigator)

  BHF British Heart Foundation

  1/10/2012 → 30/09/2015

  Project: Research

• Role of the type 2A phosphatase regulatory subunit PPP2R5A in cardiac protein phosphorylation and function

  Avkiran, M. (Primary Investigator), Marber, M. (Co-Investigator) & Mayr, M. (Co-Investigator)

  BHF British Heart Foundation

  1/10/2012 → 30/04/2016

  Project: Research

• Identifying cardiac substrates of p38a mitogen-activated protein kinase

  Marber, M. (Primary Investigator)

  1/06/2012 → 31/05/2015

  Project: Research

• Identifying cardiac substrates of p38alpha mitogen-activated protein kinase

  Marber, M. (Primary Investigator)

  MRC Medical Research Council

  1/05/2012 → 30/04/2016

  Project: Research

• Role of the type 2A phosphatase regulatory subunit PPP2R5A/B56alpha in cardiac protein phosphorylation and function

  Avkiran, M. (Primary Investigator), Marber, M. (Co-Investigator) & Mayr, M. (Co-Investigator)

  1/04/2012 → 31/03/2016

  Project: Research

• Unravelling the mechanisms and potential treatments for exercise-induced angina in coronary artery disease by Magnetic Resonance Imaging and invasive assessment of coronary haemodynamics

  Chowienczyk, P. (Primary Investigator), Marber, M. (Co-Investigator), Redwood, S. (Co-Investigator) & academic, A. (Co-Investigator)

  2/01/2012 → 1/01/2015

  Project: Research

• Unravelling the mechanisms of exercise-induced angina and the actions of GTN by magnetic resonance imaging and invasive assessment of coronary haemodynamics

  Asrress, K. (Primary Investigator), Redwood, S. (Primary Investigator), Chowienczyk, P. (Co-Investigator), Marber, M. (Co-Investigator) & academic, A. (Co-Investigator)

  BHF British Heart Foundation

  1/01/2012 → 31/12/2014

  Project: Research

• Describing the haemodynamic modification of coronary and aortic disease in severe aortic stenosis

  Redwood, S. (Primary Investigator), Khawaja, M. (Co-Investigator), Marber, M. (Co-Investigator) & Smith, N. (Co-Investigator)

  BHF British Heart Foundation

  1/01/2012 → 30/04/2015

  Project: Research

• Unraveling the mechanisms and potential treatments for exercise-induced angina in Coronary Artery Disease

  Redwood, S. (Primary Investigator), Chowienczyk, P. (Co-Investigator), Marber, M. (Co-Investigator) & academic, A. (Co-Investigator)

  1/10/2011 → 30/09/2014

  Project: Research

• Dual-sensor pressure and flow measurements in the assessment of impaired coronary microvascular and endothelial function

  Lockie, T. (Primary Investigator), Marber, M. (Primary Investigator) & Piek, J. (Co-Investigator)

  BHF British Heart Foundation

  1/10/2011 → 30/09/2014

  Project: Research

• Cardiac, aortic and peripheral haemodynamic effects of intravenous glyceryl trinitrate in patients with severe aortic stenosis

  Redwood, S. (Primary Investigator), Smith, N. (Primary Investigator) & Marber, M. (Co-Investigator)

  1/10/2011 → 30/09/2014

  Project: Research

• The role of the growth arrest and DNA damage-inducible gene 45 (GADD45) in experimental heart failure

  Marber, M. (Primary Investigator)

  1/09/2011 → 31/08/2014

  Project: Research

• REVascularisation of Ischaemic Ventricular Dysfunction (REVIVED). A randomised comparison coronary intervention versus medical therapy for treatment of heart failure

  Perera, D. (Primary Investigator), Marber, M. (Co-Investigator) & Redwood, S. (Co-Investigator)

  1/05/2011 → 30/04/2016

  Project: Research

• Validation of serum cardiac myosin binding protein C as a biomarker of myocardial injury

  Marber, M. (Primary Investigator) & academic, A. (Primary Investigator)

  1/04/2011 → 31/03/2014

  Project: Research

• Liraglutide-stimulated cardioprotection: is it novel and can it be an anti-anginal agent?

  Marber, M. (Primary Investigator) & Redwood, S. (Primary Investigator)

  BHF British Heart Foundation

  1/02/2011 → 31/01/2015

  Project: Research