Search results

• Finished

  Using protein-protein inhibitors to target p38α during myocardial ischemia

  De Nicola, G. & Marber, M.

  MRC Medical Research Council

  19/05/2019 → 18/03/2020

  Project: Research

  • Inhibitor 100%
  • Protein 100%

• The biological variability of cardiac myosin-binding protein C (cMyC) and its ability to assist in the early triage of patients with suspected acute myocardial infarction

  Marber, M.

  BHF British Heart Foundation

  1/02/2019 → 31/01/2021

  Project: Research

• Microvascular Inflammation in heart failure with preserved ejection fraction (HFpEF)

  Redwood, S., Marber, M. & Allen, C.

  BHF British Heart Foundation

  1/01/2019 → 31/12/2021

  Project: Research

• Non-invasive Differentiation of Microvascular Disease from CAD by Perfusion CMR: Validation Against Invasive Indices of Microvascular Function.

  Chiribiri, A., Ismail, T., Marber, M. & Redwood, S.

  1/09/2017 → 31/08/2020

  Project: Research

• Cardiac Myosin-Binding Protein C (cMyC) in myocardial infarction

  Marber, M.

  1/08/2017 → 31/07/2020

  Project: Research

• NIHR Biomedical Research Centre. Funding for Financial Years 2017/18, 2018/19

  Wolfe, C., Parsons, M., Gould, H., Corrigan, C., Greenough, A., Peakman, M., Vyse, T., Antoniou, M., Oakey, R., McGrath, J., Karagiannis, S., Barker, J., Flohr, C., Tziotzios, C., Whittaker, S., Spector, T., Watt, F., Hayday, A., Spencer, J., Cope, A., Malim, M., Martin Serrano, J., Edgeworth, J., Cason, J., Lord, G., Dorling, A., Sacks, S., Sanchez Fueyo, A., Lombardi, G., Ostermann, M., Shah, A., Marber, M., Mayr, M., Chowienczyk, P., Wells, C., Grigoriadis, A., Sawyer, E., Maher, J., Tribe, R., Ilic, D., Poston, L., Rutherford, M., Gee, T., Blower, P., Edwards, D., Sharpe, P., Streit, A., Naglik, J., Tavassoli, M. & McNaughton, P.

  NIHR National Institute For Health & Care Research

  1/04/2017 → 31/03/2022

  Project: Research

  • Research Centre 100%
  • Medical Research 100%

• King’s NMR Facility for structural biology, metabolic profiling and drug discovery

  Conte, M., Avkiran, M., Blower, P., Dodding, M., Eaton, P., Gautel, M., Irving, M., Malim, M., Marber, M., Mayr, M., McDonnell, J., Otsu, K., Pastore, A., Pfuhl, M., Poston, L., Shah, A., Shanahan, C., Shattock, M. & Williamson, C.

  BHF British Heart Foundation, Wellcome Trust

  1/01/2017 → 31/12/2021

  Project: Research

• Developing inhibitors of the p38a-TAB1 protein interaction

  De Nicola, G. & Marber, M.

  1/01/2017 → 30/06/2018

  Project: Research

• Non-invasive Differentiation of Microvascular Disease from CAD by Perfusion CMR: Validation Against Invasive Indices of Microvascular Function.

  Chiribiri, A., Marber, M. & Redwood, S.

  1/09/2016 → 31/08/2019

  Project: Research

• Mechanisms of action of intervention in the PHOENIX trial: in women with preterm pre-eclampsia does planned delivery improve postpartum maternal cardiac function through attenuation of myocardial ischaemia at time of disease (PHOEBE study)?

  McCarthy, F., Chappell, L., Marber, M., Poston, L. & Seed, P.

  NIHR National Institute For Health & Care Research

  1/01/2016 → 30/09/2019

  Project: Research

• Characterising novel, and discovering new, biomarkers of early myocardial injury

  Marber, M., Kaier, T., Mayr, M. & Perera, D.

  BHF British Heart Foundation

  1/10/2015 → 30/09/2018

  Project: Research

• Investigating the haemodynamic and physiological principles underlying exercise induced angina, and glyceryl trinitrates anti-anginal effect, using invasive coronary and ventricular measures of coronary flow and cardiac work

  Redwood, S., Joseph, J. & Marber, M.

  BHF British Heart Foundation

  1/10/2015 → 5/10/2018

  Project: Research

• Physiological role of RSK-mediated cardiac myosin-binding protein C phosphorylation

  Avkiran, M., Gautel, M. & Marber, M.

  1/10/2015 → 30/09/2018

  Project: Research

• Comparison between Propofol and Inhaled Anaesthesia on cardiovascular morbidity and mortality following cardiac survery (COPIA) - a Multicentre Randomised Controlled Trial

  academic, A. & Marber, M.

  1/09/2015 → 31/08/2020

  Project: Research

• C-terminal phosphorylation of the sarcomeric Z-disk protein telethonin in the heart: Functional role and molecular mechanisms

  Avkiran, M., Gautel, M. & Marber, M.

  1/07/2015 → 30/06/2019

  Project: Research

• Non-invasive differentiation of myocardial microvascular disease from epicardial coronary artery disease by perfusion CMR: validation against invasive indices of microvascular function.

  Chiribiri, A., Marber, M. & Redwood, S.

  1/07/2015 → 30/06/2018

  Project: Research

• Comparing the Diagnostic and Prognostic Performance of Myosin Binding Protein C to Troponin I and Troponin T in Patients Presenting with Chest Pain

  Marber, M.

  BHF British Heart Foundation

  1/06/2015 → 30/04/2016

  Project: Research

• An ischaemic cardiogenic shock swine model and randomised clinical study on the effects of cardiac assist strategies on coronary haemodynamics and myocardial oxygen consumption.

  Perera, D. & Marber, M.

  1/06/2015 → 1/12/2017

  Project: Research

• The haemodynamic effects of cardiac assist strategies.

  Perera, D. & Marber, M.

  1/06/2015 → 30/11/2017

  Project: Research

• Understanding the interaction between p38alpha mitogen-activated protein kinase and TAB1

  Marber, M. & Conte, M.

  BHF British Heart Foundation

  18/05/2015 → 17/05/2019

  Project: Research

• A cardiogenic shock swine model and clinical randomised study on the effects of cardiac assist strategies on myocardial oxygen supply and demand.

  Perera, D. & Marber, M.

  3/05/2015 → 2/11/2017

  Project: Research

• Comparison between Propofol and Inhaled Anaesthesia on cardiovascular morbidity and mortality following cardiac surgery (COPIA) - a Multicentre Randomised Controlled Trial

  academic, A., Clark, J., Marber, M. & Mayr, M.

  1/05/2015 → 30/04/2016

  Project: Research

• A proof of concept study for improved clinical management of patients with acute myocarditis based on a novel imaging algorithm T1 mapping

  Nagel, E., Marber, M., Mayr, M. & Puntmann, V.

  1/01/2015 → 31/12/2018

  Project: Research

• Strategies for optimal iron repletion in chronic heart failure

  Okonko, D., Marber, M. & Shah, A.

  1/09/2014 → 1/09/2017

  Project: Research

• Comparison of propofol with isoflurane anaesthesia and clinical outcome after cardiac surgery (COPIA): a multicentre randomised controlled trial

  Ballard, C. & Marber, M.

  1/09/2014 → 31/08/2018

  Project: Research

• A randomised haemodynamic study on IABP and Impella in a swine model and in patients undergoing high risk PCI

  Marber, M.

  1/05/2014 → 1/05/2017

  Project: Research

• Comparison of the pathophysiological aetiology of exercise vs mental stress-induced myocardial ischaemia

  Redwood, S. & Marber, M.

  BHF British Heart Foundation

  2/10/2013 → 31/12/2016

  Project: Research

• REVIVED - REVascularisation of Ischaemic Ventricular Dysfunction

  Perera, D., Marber, M. & Redwood, S.

  NIHR National Institute For Health & Care Research

  1/06/2013 → 31/12/2022

  Project: Research

• The assessment of cMyBP-C as a new diagnostic biomarker of myocardial infarction

  Marber, M. & Redwood, S.

  1/04/2013 → 31/03/2016

  Project: Research

• Elucidating the development of uremic cardiomyopathy in chronic kidney disease patients - are circulating cardiotonic steroids the missing link?

  Pavlovic, D. & Marber, M.

  10/01/2013 → 9/01/2018

  Project: Research

• Developing inhibitors of the p38α:TAB1 interaction

  Marber, M.

  KHP King's Health Partners

  7/01/2013 → 31/10/2014

  Project: Research

• Investigating the haemodynamic and physiological principles underlying cold induced angina using invasive coronary measures of flow and cardiac workload

  Marber, M. & Redwood, S.

  BHF British Heart Foundation

  1/01/2013 → 1/10/2017

  Project: Research

• The assessment of coronary blood flow and myocardial work in patients with warm-up angina; increased flow or reduced need?

  Marber, M., Redwood, S., Chowienczyk, P., Perera, D. & academic, A.

  BHF British Heart Foundation

  1/10/2012 → 30/09/2015

  Project: Research

• Role of the type 2A phosphatase regulatory subunit PPP2R5A in cardiac protein phosphorylation and function

  Avkiran, M., Marber, M. & Mayr, M.

  BHF British Heart Foundation

  1/10/2012 → 30/04/2016

  Project: Research

• Identifying cardiac substrates of p38a mitogen-activated protein kinase

  Marber, M.

  1/06/2012 → 31/05/2015

  Project: Research

• Identifying cardiac substrates of p38alpha mitogen-activated protein kinase

  Marber, M.

  MRC Medical Research Council

  1/05/2012 → 30/04/2016

  Project: Research

• Role of the type 2A phosphatase regulatory subunit PPP2R5A/B56alpha in cardiac protein phosphorylation and function

  Avkiran, M., Marber, M. & Mayr, M.

  1/04/2012 → 31/03/2016

  Project: Research

• Unravelling the mechanisms and potential treatments for exercise-induced angina in coronary artery disease by Magnetic Resonance Imaging and invasive assessment of coronary haemodynamics

  Chowienczyk, P., Marber, M., Redwood, S. & academic, A.

  2/01/2012 → 1/01/2015

  Project: Research

• Unravelling the mechanisms of exercise-induced angina and the actions of GTN by magnetic resonance imaging and invasive assessment of coronary haemodynamics

  Asrress, K., Redwood, S., Chowienczyk, P., Marber, M. & academic, A.

  BHF British Heart Foundation

  1/01/2012 → 31/12/2014

  Project: Research

• Describing the haemodynamic modification of coronary and aortic disease in severe aortic stenosis

  Redwood, S., Khawaja, M., Marber, M. & Smith, N.

  BHF British Heart Foundation

  1/01/2012 → 30/04/2015

  Project: Research

• Dual-sensor pressure and flow measurements in the assessment of impaired coronary microvascular and endothelial function

  Lockie, T., Marber, M. & Piek, J.

  BHF British Heart Foundation

  1/10/2011 → 30/09/2014

  Project: Research

• Cardiac, aortic and peripheral haemodynamic effects of intravenous glyceryl trinitrate in patients with severe aortic stenosis

  Redwood, S., Smith, N. & Marber, M.

  1/10/2011 → 30/09/2014

  Project: Research

• Unraveling the mechanisms and potential treatments for exercise-induced angina in Coronary Artery Disease

  Redwood, S., Chowienczyk, P., Marber, M. & academic, A.

  1/10/2011 → 30/09/2014

  Project: Research

• The role of the growth arrest and DNA damage-inducible gene 45 (GADD45) in experimental heart failure

  Marber, M.

  1/09/2011 → 31/08/2014

  Project: Research

• REVascularisation of Ischaemic Ventricular Dysfunction (REVIVED). A randomised comparison coronary intervention versus medical therapy for treatment of heart failure

  Perera, D., Marber, M. & Redwood, S.

  1/05/2011 → 30/04/2016

  Project: Research

• Validation of serum cardiac myosin binding protein C as a biomarker of myocardial injury

  Marber, M. & academic, A.

  1/04/2011 → 31/03/2014

  Project: Research

• Liraglutide-stimulated cardioprotection: is it novel and can it be an anti-anginal agent?

  Marber, M. & Redwood, S.

  BHF British Heart Foundation

  1/02/2011 → 31/01/2015

  Project: Research

• C6-substitution of lysine in mice to find binding partners of an established and novel cardiac kinase

  Marber, M.

  GSK GlaxoSmithKline Research & Development Ltd

  1/01/2011 → 5/09/2015

  Project: Research

• Preventing TAB1-mediated p38 activation during myocardial infarction

  Conte, M., Marber, M. & Sutton, B.

  MRC Medical Research Council

  1/12/2010 → 28/02/2015

  Project: Research

• Preventing TAB1-mediated p38 activation during myocardial infarction

  Conte, M., Marber, M. & Sutton, B.

  1/12/2010 → 30/11/2013

  Project: Research