Min Zhang

2023

Circ-sh3rf3/GATA-4/miR-29a regulatory axis in fibroblast-myofibroblast differentiation and myocardial fibrosis

Ma, C-X., Wei, Z-R., Sun, T., Yang, M-H., Sun, Y-Q., Kai, K-L., Shi, J-C., Zhou, M-J., Wang, Z-W., Chen, J., Li, W., Wang, T-Q., Zhang, S-F., Xue, L., Zhang, M., Yin, Q. & Zang, M-X., 24 Jan 2023, In: Cellular and molecular life sciences : CMLS. 80, 2, p. 50 50.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Nicotinamide Adenosine Dinucleotide Phosphate Oxidase-Mediated Signaling in Cardiac Remodeling

Visnagri, A., Oexner, R., Kmiotek-Wasylewska, K., Zhang, M., Zoccarato, A. & Shah, A., 1 Feb 2023, In: Antioxidants & redox signaling. 38, 4-6, p. 371-387 17 p.

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

2022

Celastrol: A Promising Agent Fighting against Cardiovascular Diseases

Li, Z., Zhang, J., Duan, X., Zhao, G. & Zhang, M., Aug 2022, In: Antioxidants. 11, 8, 1597.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Citations (Scopus)

Editorial: Chronic inflammation and pharmacological interventions in cardiovascular diseases

Wang, X., Zhang, M. & Wang, X., 24 Aug 2022, In: Frontiers in Pharmacology. 13, 993569.

Research output: Contribution to journal › Editorial › peer-review

Open Access

2021

Endothelial NADPH oxidase 4 protects against angiotensin II-induced cardiac fibrosis and inflammation

Wang, M., Murdoch, C. E., Brewer, A. C., Ivetic, A., Evans, P., Shah, A. M. & Zhang, M., Apr 2021, In: ESC Heart Failure. 8, 2, p. 1427-1437 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Citations (Scopus)

Endothelial Nox2 Limits Systemic Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4

Trevelin, S. C., Sag, C. M., Zhang, M., Alves-Filho, J. C., Cunha, T. M., Santos, C. X. D., Sawyer, G., Murray, T., Brewer, A., Laurindo, F. R. M., Protti, A., Lopes, L. R., Ivetic, A., Cunha, F. Q. & Shah, A. M., 1 Aug 2021, In: Shock (Augusta, Ga.). 56, 2, p. 268-277 10 p.

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Enhanced Heart Failure in Redox-Dead Cys17Ser PKARIα Knock-In Mice

Islam, M. M. T., Tarnowski, D., Zhang, M., Trum, M., Lebek, S., Mustroph, J., Daniel, H., Moellencamp, J., Pabel, S., Sossalla, S., El-Armouche, A., Nikolaev, V. O., Shah, A. M., Eaton, P., Maier, L. S., Sag, C. M. & Wagner, S., 5 Oct 2021, In: Journal of the American Heart Association. 10, 19, p. e021985 e021985.

Research output: Contribution to journal › Article › peer-review

Open Access

NADPH oxidase-4 promotes eccentric cardiac hypertrophy in response to volume overload

Schnelle, M., Sawyer, I., Anilkumar, N., Mohamed, B. A., Richards, D. A., Toischer, K., Zhang, M., Catibog, N., Sawyer, G., Mongue-Din, H., Schröder, K., Hasenfuss, G. & Shah, A. M., 1 Jan 2021, In: Cardiovascular Research. 117, 1, p. 178-187 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Citations (Scopus)

Role of oxidative stress in calcific aortic valve disease and its therapeutic implications

Z E Greenberg, H., Zhao, G., Shah, A. & Zhang, M., 21 Apr 2021, In: Cardiovascular Research.

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Citations (Scopus)

X-box binding protein 1-mediated COL4A1s secretion regulates communication between vascular smooth muscle and stem/progenitor cells

Angbohang, A., Huang, L., Li, Y., Zhao, Y., Gong, Y., Fu, Y., Mao, C., Morales, J., Luo, P., Ehteramyan, M., Gao, Y., Margariti, A., Gu, W., Zhang, M., Smith, A., Shah, A. M., Li, T., Kong, W. & Zeng, L., 1 Jan 2021, In: Journal of Biological Chemistry. 296, 100541.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Citations (Scopus)

2020

A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation

Yang, J., Moraga, A., Xu, J., Zhao, Y., Luo, P., Lao, K. H., Margariti, A., Zhao, Q., Ding, W., Wang, G., Zhang, M., Zheng, L., Zhang, Z., Hu, Y., Wang, W., Shen, L., Smith, A., Shah, A. M., Wang, Q. & Zeng, L., Apr 2020, In: Stem Cells. 38, 4, p. 556-573 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

4 Citations (Scopus)

115 Downloads (Pure)

Celastrol Alleviates Aortic Valve Calcification Via Inhibition of NADPH Oxidase 2 in Valvular Interstitial Cells

Liu, H., Wang, L., Pan, Y., Wang, X., Ding, Y., Zhou, C., Shah, A. M., Zhao, G. & Zhang, M., 1 Jan 2020, In: JACC: Basic to Translational Science. 5, 1, p. 35-49 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Citations (Scopus)

Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)–Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells

Harrison, C., Cellone Trevelin, S., Richards, D., Xavier Da Costa Dos Santos, C., Sawyer, G., Markovinovic, A., Zhang, X., Zhang, M., Brewer, A., Yin, X., Mayr, M. & Shah, A., 15 Oct 2020, (E-pub ahead of print) In: Arteriosclerosis, Thrombosis, and Vascular Biology.

Research output: Contribution to journal › Article › peer-review

Open Access

File

21 Citations (Scopus)

71 Downloads (Pure)

Nitric oxide fine-tunes NHE1 to control cardiomyocyte pH

Zhang, M. & Shah, A. M., 1 Oct 2020, In: Cardiovascular Research. 116, 12, p. 1925-1926 2 p.

Research output: Contribution to journal › Editorial › peer-review

2019

Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension

Rudyk, O., Rowan, A., Prysyazhna, O., Krasemann, S., Hartmann, K., Zhang, M., Shah, A. M., Ruppert, C., Weiss, A., Schermuly, R. T., Ida, T., Akaike, T., Zhao, L. & Eaton, P., 25 Jun 2019, In: PNAS. 116, 26, p. 13016-13025 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

13 Citations (Scopus)

146 Downloads (Pure)

2018

Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions

Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., 5 Feb 2018, In: Developmental Cell. 44, 3, p. 326-336

Research output: Contribution to journal › Article › peer-review

Open Access

File

88 Citations (Scopus)

66 Downloads (Pure)

Echocardiographic evaluation of diastolic function in mouse models of heart disease

Schnelle, M., Catibog, N., Zhang, M., Nabeebaccus, A. A., Anderson, G., Richards, D. A., Sawyer, G., Zhang, X., Toischer, K., Hasenfuss, G., Monaghan, M. J. & Shah, A. M., 1 Jan 2018, In: Journal of Molecular and Cellular Cardiology. 114, p. 20-28 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

87 Citations (Scopus)

186 Downloads (Pure)

Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise

Hancock, M., Hafstad, A. D., Nabeebaccus, A. A., Catibog, N., Logan, A., Smyrnias, I., Hansen, S. S., Lanner, J., Schröder, K., Murphy, M. P., Shah, A. M. & Zhang, M., 27 Dec 2018, In: eLife. 7

Research output: Contribution to journal › Article › peer-review

Open Access

36 Citations (Scopus)

2017

Both cardiomyocyte and endothelial cell Nox4 mediate protection against hemodynamic overload-induced remodelling

Zhang, M., Mongue-Din, H., Martin, D., Catibog, N., Smyrnias, I., Zhang, X., Yu, B., Wang, M., Brandes, R. P., Schröder, K. & Shah, A. M., 13 Oct 2017, (E-pub ahead of print) In: Cardiovascular Research.

Research output: Contribution to journal › Article › peer-review

Open Access

File

49 Citations (Scopus)

157 Downloads (Pure)

NADPH Oxidase-4 Driven Cardiac Macrophage Polarization Protects Against Myocardial Infarction–Induced Remodeling

Mongue-Din, H., Patel, A. S., Looi, Y. H., Grieve, D. J., Anilkumar, N., Sirker, A., Dong, X., Brewer, A. C., Zhang, M., Smith, A. & Shah, A. M., 25 Dec 2017, (E-pub ahead of print) In: JACC: Basic to Translational Science. 2, 6, p. 688-698 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

37 Citations (Scopus)

178 Downloads (Pure)

Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

Nabeebaccus, A. A., Zoccarato, A., Hafstad, A. D., Santos, C. X., Aasum, E., Brewer, A. C., Zhang, M., Beretta, M., Yin, X., West, J. A., Schröder, K., Griffin, J. L., Eykyn, T. R., Abel, E. D., Mayr, M. & Shah, A. M., 21 Dec 2017, (E-pub ahead of print) In: JCI Insight. 2, 24, p. 1-16 10.1172/jci.insight.96184.

Research output: Contribution to journal › Article › peer-review

Open Access

File

41 Citations (Scopus)

180 Downloads (Pure)

2016

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

Trevelin, S. C., Dos Santos, C. X., Ferreira, R. G., de Sá Lima, L., Silva, R. L., Scavone, C., Curi, R., Alves-Filho, J. C., Cunha, T. M., Roxo-Júnior, P., Cervi, M-C., Laurindo, F. R. M., Hothersall, J. S., Cobb, A. M., Zhang, M., Ivetic, A., Shah, A. M., Lopes, L. R. & Cunha, F. Q., 4 Oct 2016, In: Scientific Reports. 6, 34581.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Citations (Scopus)

Cell-specific effects of Nox2 on the acute and chronic response to myocardial infarction

Sirker, A., Murdoch, C. E., Protti, A., Sawyer, G. J., Santos, C. X. C., Martin, D., Zhang, X., Brewer, A. C., Zhang, M. & Shah, A. M., Sept 2016, In: Journal of Molecular and Cellular Cardiology. 98, p. 11-17 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

34 Citations (Scopus)

165 Downloads (Pure)

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling

Santos, C. X., Hafstad, A. D., Beretta, M., Zhang, M., Molenaar, C., Kopec, J., Fotinou, D., Murray, T. V., Cobb, A. M., Martin, D., Zeh Silva, M., Anilkumar, N., Schröder, K., Shanahan, C. M., Brewer, A., Brandes, R. P., Blanc, E., Parsons, M., Belousov, V., Cammack, R., & 3 othersHider, R. C., Steiner, R. A. & Shah, A. M., 1 Feb 2016, In: The EMBO journal. 35, 2, p. 319-334 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

85 Citations (Scopus)

463 Downloads (Pure)

2015

Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart

Nabeebaccus, A., Hafstad, A., Eykyn, T., Yin, X., Brewer, A., Zhang, M., Mayr, M. & Shah, A., 26 Feb 2015, In: Lancet. 385 Suppl 1, p. S73

Research output: Contribution to journal › Article › peer-review

Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

Zhang, M., Prosser, B. L., Bamboye, M. A., Gondim, A. N. S., Santos, C. X., Martin, D., Ghigo, A., Perino, A., Brewer, A. C., Ward, C. W., Hirsch, E., Lederer, W. J. & Shah, A. M., 21 Jul 2015, In: Journal of the American College of Cardiology. 66, 3, p. 261-272 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

73 Citations (Scopus)

127 Downloads (Pure)

Nicotinamide adenine dinucleotide phosphate oxidase-4-dependent upregulation of nuclear factor erythroid-derived 2-like 2 protects the heart during chronic pressure overload

Smyrnias, I., Zhang, X., Zhang, M., Murray, T. V. A., Brandes, R. P., Schröder, K., Brewer, A. C. & Shah, A. M., 4 Mar 2015, In: Hypertension. 65, 3, p. 547-553 7 p.

Research output: Contribution to journal › Article › peer-review

56 Citations (Scopus)

Nox4 is dispensable for exercise induced muscle fibre switch

Vogel, J., De Rezende, F. F., Rohrbach, S., Zhang, M. & Schröder, K., 17 Jun 2015, In: PL o S One . 10, 6, e0130769.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Citations (Scopus)

Nox4 supports proper capillary growth in exercise and retina neo-vascularization

Vogel, J., Kruse, C., Zhang, M. & Schröder, K., 11 May 2015, In: The Journal of Physiology. 593, 9, p. 2145-2154 10 p.

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription

Murray, T. V. A., Smyrnias, I., Schnelle, M., Mistry, R. K., Zhang, M., Beretta, M., Martin, D., Anilkumar, N., de Silva, S. M., Shah, A. M. & Brewer, A. C., 1 Feb 2015, In: Journal of Molecular and Cellular Cardiology. 79, p. 54-68 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

2014

Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through pro-inflammatory effects and endothelial-mesenchymal transition

Murdoch, C., Chaubey, S., Zeng, L., Yu, B., Ivetic, A., Walker, S. J., Vanhoutte, D., Heymans, S., Grieve, D. J., Cave, A. C., Brewer, A. C., Zhang, M., Shah, A. M. & Ivetic, A., 24 Jun 2014, In: Journal of the American College of Cardiology. 63, 24, p. 2734-2741 8 p.

Research output: Contribution to journal › Article › peer-review

149 Citations (Scopus)

Erratum to: Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction (Basic Res Cardiol (2011) 106, (527-538) DOI:10.1007/s00395-011-0179-7)

Murdoch, C. E., Alom-Ruiz, S. P., Wang, M., Zhang, M., Walker, S., Yu, B., Brewer, A. & Shah, A. M., 2014, In: Basic Research in Cardiology. 109, 3, 410.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

ROS signalling between endothelial cells and cardiac cells

Zhang, M. & Shah, A. M., 1 May 2014, In: Cardiovascular Research. 102, 2, p. 249-257 9 p.

Research output: Contribution to journal › Literature review › peer-review

Open Access

77 Citations (Scopus)

2013

Gene Network and Proteomic Analyses of Cardiac Responses to Pathological and Physiological Stress

Drozdov, I., Didangelos, A., Yin, X., Zampetaki, A., Abonnenc, M., Murdoch, C., Zhang, M., Ouzounis, C. A., Mayr, M., Tsoka, S. & Shah, A. M., Dec 2013, In: Circulation-Cardiovascular Genetics. 6, 6, p. 588-597 10 p.

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

NADPH Oxidases in Heart Failure: Poachers or Gamekeepers?

Zhang, M., Perino, A., Ghigo, A., Hirsch, E. & Shah, A. M., 20 Mar 2013, In: ANTIOXIDANTS AND REDOX SIGNALING. 18, 9, p. 1024-1041 18 p., N/A.

Research output: Contribution to journal › Literature review › peer-review

161 Citations (Scopus)

2012

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

Schroeder, K., Zhang, M., Benkhoff, S., Mieth, A., Pliquett, R., Kosowski, J., Kruse, C., Luedike, P., Michaelis, U. R., Weissmann, N., Dimmeler, S., Shah, A. M. & Brandes, R. P., 27 Apr 2012, In: Circulation Research. 110, 9, p. 1217-1225 8 p.

Research output: Contribution to journal › Article › peer-review

499 Citations (Scopus)

Response to the Letter by Schmidt et al Regarding "Nox4 Is a Janus-Faced Reactive Oxygen Species Generating NADPH Oxidase"

Schroeder, K., Benkhoff, S., Mieth, A., Pliquett, R., Kosowski, J., Kruse, C., Michaelis, U. R., Dimmeler, S., Brandes, R. P., Zhang, M., Shah, A. M., Luedike, P. & Weissmann, N., 22 Jun 2012, In: Circulation Research. 111, 1, p. E17-E18 2 p.

Research output: Contribution to journal › Letter › peer-review

2011

Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo

Ray, R., Murdoch, C. E., Wang, M., Santos, C. X., Zhang, M., Alom-Ruiz, S., Anilkumar, N., Ouattara, A., Cave, A. C., Walker, S. J., Grieve, D. J., Charles, R. L., Eaton, P., Brewer, A. C. & Shah, A. M., Jun 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 6, p. 1368-1376 9 p.

Research output: Contribution to journal › Article › peer-review

261 Citations (Scopus)

NADPH oxidases and cardiac remodelling

Nabeebaccus, A., Zhang, M. & Shah, A. M., Jan 2011, In: Heart Failure Reviews. 16, 1, p. 5 - 12 8 p.

Research output: Contribution to journal › Article › peer-review

116 Citations (Scopus)

NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies

Sirker, A., Zhang, M. & Shah, A. M., Sept 2011, In: Basic Research in Cardiology. 106, 5, p. 735 - 747 13 p.

Research output: Contribution to journal › Literature review › peer-review

147 Citations (Scopus)

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

Brewer, AC., Murray, T., Arno, M., Zhang, M., Anilkumar, N., Mann, G. & Shah, AM., 1 Jul 2011, In: Free Radical Biology and Medicine. 51, 1, p. 205 - 215 11 p.

Research output: Contribution to journal › Article › peer-review

135 Citations (Scopus)

Redox signaling in cardiac myocytes

Xavier Da Costa Dos Santos, C. S., Anilkumar, N., Zhang, M., Brewer, A. C. & Shah, A. M., 1 Apr 2011, In: Free Radical Biology and Medicine. 50, 7, p. 777 - 793 17 p.

Research output: Contribution to journal › Literature review › peer-review

267 Citations (Scopus)

Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction

Murdoch, C., Alom-Ruiz, SP., Wang, M., Zhang, M., Yu, B., Brewer, AC. & Shah, AM., Jul 2011, In: Basic Research in Cardiology. 106, 4, p. 527 - 538 12 p.

Research output: Contribution to journal › Article › peer-review

128 Citations (Scopus)

2010

CARDIOMYOCYTE-SPECIFIC OVEREXPRESSION OF NOX4 ATTENUATES ADVERSE CARDIAC REMODELLING AFTER MYOCARDIAL INFARCTION

Zhang, M., Looi, Y. H., Brewer, A. C. & Shah, A. M., 2010, In: Heart. 96, 4

Research output: Contribution to journal › Meeting abstract

ENDOTHELIAL NOX4 NADPH OXIDASE ENHANCES VASODILATATION VIA HYDROGEN PEROXIDE-INDUCED HYPERPOLARISATION AND REDUCES BLOOD PRESSURE

Wang, M., Ray, R., Murdoch, C., Zhang, M., Walker, S. J., Brewer, A. C. & Shah, A. M., 2010, In: Heart. 96, 4

Research output: Contribution to journal › Meeting abstract

ENDOTHELIAL-SPECIFIC OVEREXPRESSION OF NOX2 ENHANCES ANGIOTENSIN II-INDUCED CARDIAC DYSFUNCTION AND FIBROSIS

Murdoch, C. E., Brewer, A., Zhang, M., Vanhoutte, D., Heymans, S. & Shah, A. M., 2010, In: Heart. 96, 4

Research output: Contribution to journal › Meeting abstract

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

Zhang, M., Brewer, A. C., Schröder, K., Xavier Da Costa Dos Santos, C. S., Grieve, D. J., Wang, M., Anilkumar, N., Yu, B., Dong, X., Walker, S. J., Brandes, R. P. & Shah, A. M., 19 Oct 2010, In: Proceedings of National Academy of Sciences USA. 107, 42, p. 18121-6 6 p.

Research output: Contribution to journal › Article › peer-review

379 Citations (Scopus)

The H2O2-producing NADPH Oxidase Nox4 Protects Against Angiotensin II Induced Vascular Hypertrophy and Inflammation

Schroeder, K., Mieth, A., Benkhoff, S., Zhang, M., Shah, A. M. & Brandes, R. P., 2010, In: Free Radical Biology and Medicine. 49, p. S29-S29

Research output: Contribution to journal › Meeting abstract

2009

Cardiomyocyte-specific Overexpression of Nox4 Attenuates Adverse Cardiac Remodeling After Myocardial Infarction

Zhang, M., Looi, Y. H., Brewer, A. C. & Shah, A. M., 2009, In: Circulation (Baltimore). 120, 18, p. S1097 - S1097

Research output: Contribution to journal › Meeting abstract

Defective peroxisomal proliferators activated receptor gamma activity due to dominant‐negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice

Kis, A., Murdoch, C., Zhang, M., Siva, A., Rodriguez-Cuenca, S., Carobbio, S., Lukasik, A., Blount, M., O'Rahilly, S., Gray, S. L., Shah, A. M. & Vidal-Puig, A., Jun 2009, In: EUROPEAN JOURNAL OF HEART FAILURE. 11, 6, p. 533 - 541 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Citations (Scopus)

Min Zhang

Research output

Search results